Cymbalta vs. Lexapro: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Cymbalta neLexapro mishonga miviri yemishonga inowanzoshandiswa kurapa zvese zvakanyanya kushushikana kwepfungwa (MDD) uye yakajairika kunetseka kusagadzikana (GAD). Huru kushungurudzika kusagadzikana kuri inofungidzirwa kukanganisa vangangoita mamirioni gumi nematanhatu vakuru muUnited States. Iyo inoratidzirwa nemamiriro ekudzikira kweinenge vhiki mbiri-nguva. Varwere vanogona zvakare kuratidza kurasikirwa kwechido mune zviitiko zvavanowanzo farira kana simba rakaderera. Vamwe varwere vanorwadziwa pasina chero chikonzero chinozivikanwa.
Yakajairika kushungurudzika kusagadzikana kuri inofungidzirwa kukanganisa 6.8 mamirioni vakuru muUnited States. Iyo inoratidzirwa nekunyanyisa kunetseka nezve dzakasiyana nyaya dzinosanganisira mari, mhuri, hutano, uye basa. Inoonekwa kana varwere vachiratidza kunetseka pamusoro pemamwe mazuva pane kwete kwemwedzi mitanhatu.
Nepo Cymbalta neLexapro vari vaviri vachishandiswa kurapa aya mamiriro uye nevamwe vazhinji, pane misiyano yakakura pakati pemishonga iyi miviri.
Ndeupi mutsauko mukuru pakati peCymbalta neLexapro?
Cymbalta (duloxetine) imishonga yemishonga inoratidzwa mukurapa kweese MDD neGAD. Cymbalta ndeyeboka remishonga inodzvinyirira inozivikanwa seinosarudza serotonin-norepinephrine reuptake inhibitors (SNRIs). Mune iyo neuron synapse, Cymbalta inovhara iyo reuptake yeese norepinephrine uye serotonin. Izvi zvinosiya maurotransmitter anowanikwa zvirinyore kuti atambe chinhanho chakanaka pane manzwiro uye kukanganisa. Dzimwe SNRIs iwe dzaungave uchiziva nadzo ndeyeExpexor (venlafaxine) uye Pristiq (desvenlafaxine).
Cymbalta inowanikwa se 20 mg, 30 mg, uye 60 mg yemuromo capsule.
Lexapro (escitalopram) zvakare mishonga inonyorwa inoratidzwa mukurapa kweese MDD neGAD. Lexapro ndeyeboka remishonga inodzvinyirira inozivikanwa seinosarudza serotonin reuptake inhibitors (SSRIs). Lexapro inoshanda nekuvhara iyo reuptake yeserotonin pane iyo neuronal membrane yekufambisa pombi. Ichi chiito zvinobudirira chinosiya yakasununguka serotonin muiyo neuron synapse. Zvimwe SSRIs iwe unogona kunge uchiziva nezvazvo zvinosanganisira Prozac, Zoloft, Celexa, kana Paxil.
Lexapro inowanikwa sehwendefa remuromo musimba re5 mg, 10 mg, uye 20 mg. Inowanikwawo semhinduro yemumuromo mune 5 mg / 5 ml kusangana.
| Misiyano mikuru pakati peCymbalta neLexapro | ||
|---|---|---|
| Cymbalta | Lexapro | |
| Kirasi yemishonga | Inosarudza serotonin-norepinephrine reuptake inhibitor | Inosarudza serotonin reuptake inhibitor |
| Brand / generic chinzvimbo | Brand uye generic inowanikwa | Brand uye generic inowanikwa |
| Chii chinonzi generic zita? | Duloxetine | Escitalopram |
| Ndeapi mafomu (s) ayo mushonga unouya? | Oral capsules | Piritsi yemuromo uye mhinduro yemumuromo |
| Ndeipi muyero wakajairwa? | 60 mg kamwe pazuva | 10 mg kamwe pazuva |
| Yakareba sei iyo yekurapa? | Yakareba-nguva (mwedzi kusvika makore) | Yakareba-nguva (mwedzi kusvika makore) |
| Ndiani anowanzoshandisa mushonga? | Vechidiki nevakuru | Vechidiki nevakuru |
Mamiriro ezvinhu anorapwa neCymbalta uye Lexapro
Sezvambotaurwa, Cymbalta naLexapro vese vari vaviri vanoratidzirwa kubata ese makuru kushushikana kwepfungwa uye yakajairika kusagadzikana kusagadzikana. Cymbalta inogamuchirwa kune zvimwe zvakasarudzika zvinoratidza zvine chekuita neuropathic uye musculoskeletal kurwadziwa. Izvi zvinoratidza Cymbalta kunze kwemimwe mishonga yekudzvinyirira sezvo iriyo yega inogamuchirwa mukuongororwa kwakabatana nekurwadziwa. Lexapro dzimwe nguva inoshandiswa kure-kunyorera mamiriro akadai sekunyanyisa kusagadzikana kusagadzikana, bulimia nervosa, uye kudya zvakanyanya.
Iyi inotevera chati inopa rondedzero yemamiriro akabatwa naCymbalta naLexapro. Zvinogona kusasanganisira zvese zvingangoshandiswa, uye iwe unofanirwa kugara uchikurukura neyako nyanzvi yehutano kuti uone kana imwe yemishonga iyi yakakunakira iwe.
| Mamiriro | Cymbalta | Lexapro |
| Huru kushungurudzika kusagadzikana | Ehe | Ehe |
| Chirwere chekuzvidya mwoyo | Ehe | Ehe |
| Fibromyalgia | Ehe | Kwete |
| Husingaperi musculoskeletal kurwadziwa | Ehe | Kwete |
| Neuropathic kurwadziwa kwakabatana nechirwere cheshuga mellitus | Ehe | Kwete |
| Chemotherapy-inosimudzira peripheral neuropathy | Kunze-chitaridzi | Kwete |
| Kushungurudza urinary kusagadzikana (varume) | Kunze-chitaridzi | Kwete |
| Binge kudya kusagadzikana | Kwete | Kunze-chitaridzi |
| Bulimia nervosa | Kwete | Kunze-chitaridzi |
| Kucherekedza kusagadzikana kusagadzikana | Kwete | Kunze-chitaridzi |
| Panic kusagadzikana | Kwete | Kunze-chitaridzi |
| Posttraumatic kusagadzikana kusagadzikana | Kwete | Kunze-chitaridzi |
| Premenstrual dysphoric kusagadzikana | Kwete | Kunze-chitaridzi |
| Nguva isati yakwana ejaculation | Kwete | Kunze-chitaridzi |
Cymbalta kana Lexapro inoshanda zvakanyanya here?
TO meta-ongororo akaongorora zvidzidzo achienzanisa duloxetine kune escitalopram uye mamwe akajairwa SSRIs. Chidzidzo chacho chakawana kuti maererano nekurapa kwekushungurudzika kukuru, duloxetine inokundikana kuratidza mukana wakakosha maererano nekubudirira kwekurapa pamusoro peSSRIs. Zvisinei, maererano nekuongorora uku, varwere vanowanzorega duloxetine nekuda kwezviitiko zvakashata. Sekondi meta-ongororo yakaratidza izvi zvakawanikwa. Zvinogona kusakwanisika kutaura kana Cymbalta kana Lexapro iri nani pane imwe maererano nekurapa kushushikana. Iyo yakawedzera mwero wemhedzisiro neCymbalta chingave chinhu chakakosha kufunga nezvayo pakusarudza kurapwa.
Kuvhara uye kuenzanisa kwemutengo weCymbalta vs. Lexapro
Cymbalta imishonga yemishonga inowanzo kuvharwa nezvose zviri zviviri zvekutengeserana uye zveMedare zvirongwa zvemushonga. Mutengo wekunze kwehomwe weCymbalta 60 mg unogona kudarika $ 300, asi nekoponi kubva kuSingleCare, unogona kuwana generic yakaderera seUS $ 15 kuma Pharmacies ari kutora chikamu.
Lexapro zvakare iri mishonga yemishonga inowanzo kuvharwa nezvose zviri zviviri zvekutengeserana uye zveMedare zvirongwa zvemushonga. Mutengo wekunze-wehomwe kwemazuva makumi matatu ekuwanikwa kweLexapro 10 mg inogona kusvika pamadhora mazana mana. SingleCare inopa coupon yegeneric Lexapro, iyo inogona kudzikisa mutengo kusvika kumadhora gumi kana pasi.
kadhi rinodzora
| Cymbalta | Lexapro | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare? | Ehe | Ehe |
| Standard muyero | 30, 60 MG capsules | 30, 10 mg mahwendefa |
| Chaizvoizvo Medicare copay | Asingasviki $ 10 | Asingasviki $ 10 |
| SingleCare mutengo | $ 15 + | $ 10 + |
Zvakajairika mhedzisiro mhedzisiro yeCymbalta vs. Lexapro
Cymbalta neLexapro vane mikana yekukonzera mhedzisiro, asi vamwe vanowanzo kuve neumwe kana mumwe mumiririri. Nausea, semuenzaniso, yaingotaurwa mu5% yevarwere vanotora Lexapro mumakiriniki miedzo maringe ne23% yevarwere vanotora Cymbalta. Kunyangwe kusvotwa kusinga garire kwenguva refu mhedzisiro, kunogona kukanganisa hupenyu hwemunhu. Izvo zvinowanzoitika mumavhiki ekutanga ekurapwa, uye zvichipiwa kuti mishonga iyi kazhinji inotora chero kubva pamasvondo maviri kusvika matanhatu kuratidza kukanganisa kushushikana kana zviratidzo zvekushushikana, kuda kusvotwa kunogona kuve chikonzero chekumira kutanga kusati kwanyatsobatsira mushonga unozivikanwa.
Kufembera, kana kudikitira, kunoitika pamwero wakaenzana pakati pemishonga iyi miviri. Iyi divi mhedzisiro inogona kukanganisa hupenyu hwezuva nezuva hwemunhu uye kuzviremekedza, uye zvinogona kuve chikonzero varwere vanosarudza kurega mushonga.
Iyi inotevera runyorwa haina kuitirwa kuti ive izere runyorwa rweakashata zviitiko. Ndokumbirawo ubvunze wemishonga, chiremba, kana mumwe chiremba wezvekurapa kuti uwane yakazara rondedzero yemhedzisiro.
| Cymbalta | Lexapro | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Nausea | Ehe | 2. 3% | Ehe | 5% |
| Muromo wakaoma | Ehe | 13% | Ehe | 5% |
| Kudikitira | Ehe | 6% | Ehe | 5% |
| Manyoka | Ehe | 9% | Ehe | 8% |
| Kuzvimbirwa | Ehe | 9% | Ehe | 3% |
| Dyspepsia | Kwete | n / a | Ehe | 3% |
| Dzungu | Ehe | 9% | Kwete | n / a |
| Kukotsira | Ehe | 10% | Ehe | 6% |
| Kutemwa nemusoro | Ehe | 14% | Kwete | n / a |
| Kuwedzera kweropa | Ehe | piri% | Kwete | n / a |
| Kuderedza kudya | Ehe | 7% | Ehe | 3% |
| Yakadzikira libido | Kwete | n / a | Ehe | piri% |
Kunobva: Cymbalta ( Zuva Nezuva Lexapro ( Zuva Nezuva )
Kubatana kwezvinodhaka zveCymbalta vs. Lexapro
Cymbalta neLexapro imwe neimwe inogadziriswa neiyo cytochrome enzyme system iri muchiropa. Cymbalta ndiyo huru substrate yeCYP1A2, uye ine mwero inhibitor yeCYP2D6. Izvo zvakakosha kuti uzive kuti vamwe varwere vanogona kutambura nekusagadzikana kwekutarisa mukuwedzera kune kushushikana uye kusagadzikana kwekushushikana. Varwere vazhinji vane kusagadzikana kwekutarisa vanorapwa neamphetamines. Cymbalta inogona kuwedzera iyo serum yevasungwa yeamphetamines kuburikidza nekudzivirira kwayo kweCYP2D6. Varwere vanotora musanganiswa uyu vanofanirwa kuongororwa zvakanyanya.
Lexapro iri substrate hombe yeCYP2C19 uye CYP3A4, uye isina simba inhibitor yeCYP2D6.
Iko kushandiswa kweLexapro ine tricyclic antidepressants, senge amitriptyline, kunogona kuwedzera njodzi yekuwedzera kweQT uye serotonin syndrome. Kazhinji, kusanganiswa uku kunofanirwa kudzivirirwa.
Iyi inotevera rondedzero haina kuitirwa kuti ive izere runyorwa rwekudyidzana zvinodhaka. Zvakanakisisa kubvunza wako mupi kana wemishonga kune yakazara runyorwa.
| Zvinodhaka | Kirasi yemishonga | Cymbalta | Lexapro |
| Acalabrutinib Dabrafenib Erdafitinib Gilteritinib Ibrutinib | Antineoplastics | Ehe | Ehe |
| Almotriptan Eletriptan Oxitriptan | 5HT Agonist / Triptans (antimigraine vamiririri) | Ehe | Ehe |
| Amphetamine munyu Dexmethylphenidate Methylphenidate | Amphetamine | Ehe | Ehe |
| Alosetron Ondansetron Ramosetron | 5HT3 Vapikisi (anti-nausea vamiririri) | Kwete | Ehe |
| Apixaban Edoxaban | Antiplatelets | Ehe | Ehe |
| Aripiprazole | Antipsychotic | Ehe | Ehe |
| Aspirin Ibuprofen Naproxen Diclofenac | Nonsteroidal anti-anogumbura zvinodhaka (NSAIDs) | Ehe | Ehe |
| Bemiparin Enoxaparin Heparin | Anticoagulants | Kwete | Ehe |
| Bupropion | Dopamine / norepinephrine reuptake inhibitor | Kwete | Ehe |
| Buspirone | Kufunganya | Ehe | Ehe |
| Carbamazepine | Anticonvulsant | Kwete | Ehe |
| Enzalutamide | Chemotherapy mumiririri | Kwete | Ehe |
| Esomeprazole Omeprazole | Proton pombi inhibitor | Kwete | Ehe |
| Fluconazole | Antifungal | Kwete | Ehe |
| Fluoxetine Duloxetine Paroxetine Sertraline | SSRIs | Ehe | Ehe |
| Hydroxychloroquine | Aminoquinolone / Antimalarial | Kwete | Ehe |
| Linezolid | Mishonga inorwisa mabhakitiriya | Ehe | Ehe |
| Metaxalone | Tsandanyama dzinozorodza | Ehe | Ehe |
| Pimozide | Antipsychotic | Kwete | Ehe |
| Selegiline Phenelzine Rasagiline | Monoamine oxidase inhibitor (MAOI) | Ehe | Ehe |
| Wort St. | Mishonga yekuwedzera | Ehe | Ehe |
| Hydrochlorothiazide Chlorthalidone Metolazone | Thiazide diuretics | Kwete | Ehe |
| Tramadol | Opiate pain reliever | Ehe | Ehe |
| Amitriptyline Clomipramine Doxepin Nortriptyline | Tricyclic antidepressants | Ehe | Ehe |
| Venlafaxine | Kusarudza norepinephrin / serotonin reuptake inhibitor (SNRIs) | Ehe | Ehe |
Yambiro dzeCymbalta uye Lexapro
Cymbalta neLexapro hazvigadzirise iko kuregererwa kwekukurumidza kwezviratidzo zvekushushikana kwepfungwa kana kusagadzikana kusagadzikana. Zvinotora hushoma hwemavhiki maviri kuti uone chero shanduko muvazhinji varwere, uye kusvika kumavhiki mana kusvika matanhatu kuti vazive mhedzisiro yemushonga. Zvakakosha kuti varwere vanzwisise izvi saka havafaniri kurega mishonga yavo vasati vatanga nekutenda kuti haisi kushanda.
Varwere vane MDD vanogona kusangana nekuwedzera kwekushushikana kana kuzviuraya pfungwa kana ivo vari kutora antidepressant mishonga. Aya mamiriro anogona kuwedzera kusvika kuregererwa kwawanikwa. Cymbalta uye Lexapro kurapa kunogona kuwedzera kuzviuraya uye kufunga pakati pevechidiki nevakuru vechidiki, kunyanya mumatanho ekutanga ekurapa pasati paitwa chero rudzi rwekuregererwa. Varwere ava vanofanirwa kuongororwa zvakanyanya kana kurapwa uku kuchionekwa sekukosha kwachiremba. Shanduko yekurapa inogona kudikanwa kana zviratidzo zvikangoerekana zvamuka kana kuwedzera kuipa.
Pakave nemishumo yekutadza kwechiropa, dzimwe nguva kuuraya, neCymbalta. Aya makesi anogona kuunza nekurwadziwa mudumbu uye akakwirisa echiropa enzymes ane kana asina jaundice. Kunwa doro kunogona kuwedzera njodzi iyi, uye nekudaro musanganiswa uyu unofanirwa kudzivirirwa.
Serotonin syndrome yakataurwa nezvose SSRIs uye SNRIs, kusanganisira Cymbalta uye Lexapro. Ichi chiitiko chakanangana neasina kukwirira mazinga eserotonin uye zvinogona kukonzera kuti murwere anzwe kushushikana, kutenderera, uye kuwedzerwa kurova kwemoyo. Izvi zvinogona kuunzwa nekushandiswa kwemaviri serotonergic zvinodhaka pamwechete. Izvo zvakakosha kuti utaure kune iro ruzivo rwemugadziri pamusoro pekudyidzana kwemishonga kana uchipa mishonga iyi.
Inowanzo bvunzwa mibvunzo nezve Cymbalta vs. Lexapro
Chii chinonzi Cymbalta?
Cymbalta mushonga unodzvinyirira unoshandiswa pakurapa kushushikana kukuru, kusagadzikana kwekushushikana kwepfungwa, uye dzakasiyana siyana neuropathic uye musculoskeletal pain kusagadzikana. Cymbalta inowanikwa seyemuromo capsule mu 20 mg, 30 mg, uye 60 mg simba.
Chii chinonzi Lexapro?
Lexapro mushonga unodzvinyirira unoshandiswa pakurapa kwekushungurudzika kukuru uye chirwere chekushushikana kwakazara. Lexapro inowanikwa sehwendefa yemuromo mu5 mg, 10 mg, uye 20 mg simba. Inowanikwawo semhinduro yemuromo.
Ko Cymbalta neLexapro zvakafanana here?
Kunyange vese vari vaviri Cymbalta naLexapro vachirapa kushushikana uye kusagadzikana, ivo havana kufanana. Cymbalta inovhara iyo reuptake yeese serotonin uye norepinephrine mune iyo neuronal synapse, nepo Lexapro ichivhara serotonin reuptake chete. Cymbalta inotakura zvimwe zvinoratidza marwadzo ekurwadziwa.
Cymbalta kana Lexapro iri nani here?
Cymbalta neLexapro zvinoita kunge zvakafanana pakubata kurapa kushushikana. Yakakura meta-kuongororwa kweakawanda ongororo inoratidza kuti yakakwira mwero wezviitiko zvakashata neCymbalta inogona kunge iri chikonzero chekuyedza Lexapro kutanga muvarwere vazhinji.
Ndinogona here kushandisa Cymbalta kana Lexapro ndichiri nepamuviri?
Chikafu neDrug Administration (FDA) inofunga zvese nezveCymbalta neLexapro nhumbu yechikamu C, zvichireva kuti pakange pasina zvakakwana zvidzidzo zvevanhu kuona kuchengetedzeka. NaCymbalta, isiri-teratogenic mhedzisiro yakaonekwa muvacheche zvichitevera kuitiswa kweCymbalta paine pamuviri. Izvi zvinosanganisira kutambudzika kwekufema, kunetseka kwekudya, uye kudedera. Nekushandisa kweLexapro, zvidzidzo zvemhuka zvakaratidza teratogenic mhedzisiro kumucheche, kusanganisira nemhedzisiro yemhedzisiro, uye zvakagadziriswa kuti inodarika iyo placenta yemunhu. Nezvikonzero izvi, kushandiswa kweCymbalta kana Lexapro mukuzvitakura kunofanira kuyerwa kubva pane zvinogona kukuvadza mwana.
Ndinogona here kushandisa cymbalta kana lexapro nedoro?
Doro rinogona kuwedzera huturu hweCymbalta neLexapro. Kunwa doro uchinwa mishonga iyi kunogona kukonzera kukanganisika kwepfungwa, uye nekuda kwechikonzero ichi, varwere vanorayirwa kuti vadzivise doro kana vakatora Cymbalta kana Lexapro. Sezvakambokurukurwa, kunwa doro paCymbalta kunowedzera mukana wekutadza kwehepatic.
Cymbalta inobatsira nekufunganya here?
Cymbalta inogamuchirwa mukurapa kweakajairika kunetseka kusagadzikana. Varwere vanofanirwa kudzidziswa kuti mushonga haugone kupa kuregererwa kwekukurumidza kwezviratidzo zvekushushikana, uye vamwe varwere vangangoda imwe mishonga yezviitiko zvakanyanya zvekushushikana.
Cymbalta inokuita kuti ufare here?
Cymbalta inoshanda nekuwedzera iripo norepinephrine uye serotonin. Aya maurotransmitter anoita basa rakakosha mukushushikana kana kukanganisa. Varwere vanotora Cymbalta vanogona kutaura vachinzwa kufara kana kusanyanya kushushikana, kunyanya mushure memavhiki mana kusvika matanhatu ekurapwa.
Cymbalta inoshandura hunhu hwako here?
Cymbalta inokanganisa mamood nekuwedzera iripo norepinephrine uye serotonin. Kune vazhinji varwere, izvi zvinokonzeresa shanduko yakanaka muhutano hwepfungwa. Kana iwe ukaona shanduko yakaipa mauri kana mumwe munhu waunotarisira uchitora Cymbalta, kusanganisira pfungwa dzekuzviuraya kana mazano, tsvaga rubatsiro nekukasira.
