Shingrix vs.Zostavax: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Parizvino pane majekiseni maviri anogona kupihwa kudzivirira herpes zoster, inowanzozivikanwa se 'shingles': Shingrix uye Zostavax. Mushonga wechipembenene unokurudzirwa kuvanhu vakuru kana vangosvitsa makore makumi mashanu.
Vazhinji vanhu vakatapukirwa neavicella zoster virus kana vakambove nehukukurum. Mushure mokunge chickenpox yagadziriswa, iyo varicella zoster virus inorara yakarara mumuviri kwemakore, kana zvisiri zvachose. Gare gare muhupenyu, hutachiona hunogona kumisazve semabhande uye hunokonzera kuputika kunorwadza kunowanzo kuputira kumeso kana torso.
Kunyangwe Shingrix naZostavax vachishanda nenzira dzakafanana dzekudzivirira shingles, pane misiyano yakakosha pakati pezviviri.
Ndeupi mutsauko mukuru pakati peShingrix naZostavax?
Shingrix (Chii chinonzi Shingrix?) Mushonga unodzokororazve, unogadziridza zoster uyo wakatanga kugamuchirwa neDAA muna 2017. Inoshandisa varicella-zoster glycoprotein E antigen kuburitsa mhinduro mumuviri mumuviri. Anonamatira, kana chinongedzo chakawedzerwa, chinobatsira kusimudzira mhinduro yemumuviri kuutachiona. Nekuti Shingrix mushonga usingashandiswe, unogona kushandiswa mune varwere vasina immunompompised varwere kana avo vane immune system isina kusimba.
Shingrix inoiswa sejekiseni mumhasuru (intramuscular). Inopihwa muzvikamu zviviri zvakasiyana ine nguva ye mwedzi miviri kusvika mitanhatu pakati. Chipiri chechipiri chakakosha kuti uve nechokwadi chekuita kwenguva refu.
Zostavax, inogamuchirwa muna 2006, inorarama inodzivirirwa herpes zoster vaccine. Mune mamwe mazwi, Zostavax ine isina kusimba vhezheni yehutachiona chaihwo kuburitsa immune immune. Neichi chikonzero, hazvikurudzirwe kune avo vasina immunocompromised. Kana zvisina kudaro, mushonga wacho pachawo unogona kukonzera hutachiona.
Zostavax inoshandiswa sejekiseni rimwe chete pasi peganda (subcutaneous). Iyo inouya mune chando vhezheni uye a firiji-yakagadzika vhezheni . Iyo vhezheni vhezheni inofanira kuchengetwa yakaoma nechando panguva yekufambisa uye yekuchengetedza kuti ive nechokwadi chekushanda kwayo nepo firiji-yakagadzikana Zostavax inogona kuchengetwa mufiriji kudzamara ichida kushandiswa.
| Misiyano mikuru pakati peShingrix naZostavax | ||
|---|---|---|
| Shingrix | Zostavax | |
| Kirasi yemishonga | Mushonga | Mushonga |
| Brand / generic chinzvimbo | Brand zita chete | Brand zita chete |
| Chii chinonzi generic zita? | Zoster Vaccine Recombinant, Yakagadziriswa | Zoster Vaccine Live |
| Ndeapi mafomu (s) ayo mushonga unouya? | Kumiswa kwejekiseni retsono | Kumiswa kweiyo subcutaneous jekiseni |
| Ndeipi muyero wakajairwa? | Batira 1 dosi (0.5 ml) uyezve imwe dosi (0.5 ml) pakati pemwedzi miviri ne6 gare gare | Batira imwe dose (0.65 ml) kamwe |
| Yakareba sei iyo yekurapa? | Kubaya nhomba kunopera mukati memwedzi miviri kusvika kumatanhatu mushure memadhosi maviri | Mishonga yakakwana mushure me1 dose |
| Ndiani anowanzoshandisa mushonga? | Vakuru vane makore makumi mashanu zvichikwira | Vakuru vane makore makumi mashanu zvichikwira |
Mamiriro ezvinhu anorapwa naShingrix naZostavax
Shingrix naZostavax ndivo FDA inogamuchirwa kudzivirira shingles (herpes zoster). Mishonga yekudzivirira miviri iyi inoratidzirwa kudzivirira shingles muvanhu vakuru vane makore makumi mashanu zvichikwira. Shingrix naZostavax havasi kushandiswa kudzivirira hutachiona hwevaricella hutachiona, inozivikanwawo sehukupukapo.
Postherpetic neuralgia ndeye yakajairika mhando yemitsipa kurwadziwa iyo inomuka ne shingles. Nekuti Shingrix naZostavax vanogona kudzivirira shingles, vanogona zvakare kudzivirira postherpetic neuralgia (PHN) uye zvimwe zvinorwadza zvinokonzeresa kubva kune shingles. Zvisinei, majekiseni aya haana kunyorwa kuti arape PHN.
| Mamiriro | Shingrix | Zostavax |
| Kudzivirira kwehepe zoster (shingles) | Ehe | Ehe |
Shingrix kana Zostavax inoshanda zvakanyanya here?
Shingrix naZostavax vese vakaratidzirwa kudzivirira shingles. Zvisinei, Shingrix mushonga mutsva unoonekwa seunoshanda kupfuura Zostavax. Shingrix inokurudzirwa kune avo vakatowana mushonga weZostavax munguva yakapfuura.
Kliniki miedzo yakaratidza kuti Shingrix iri 97% inoshanda pakudzivirira shingles muvakuru vane makore makumi mashanu kusvika makumi matanhatu nemapfumbamwe ekuberekwa. Shingrix inoshanda zvakare mukudzivirira shingles muvakuru vakuru-vakuru vane makore anodarika makumi manomwe, Shingrix iri 91% inoshanda .
Zostavax ine 70% kushanda mwero mukudzivirira shingles muvanhu vakuru vane makore makumi mashanu kusvika makumi matanhatu nemapfumbamwe ekuberekwa, maererano neZoster Efficacy uye Safety Trial (ZEST). Mhedzisiro kubva ku Shingles Kudzivirira Kudzidza yakaratidza kuti Zostavax ine 51% inoshanda kurwisa shingles. Inofananidzwa naShingrix, kushanda kweZostavax kunoderera mumapoka akwegura. Kubva pamhedzisiro yeSPS, Zostavax ine 64% inoshanda muvakuru vane makore makumi matanhatu kusvika makumi matanhatu nemapfumbamwe ekuberekwa; 41% inoshanda muvakuru vane makore makumi manomwe kusvika makumi manomwe nemapfumbamwe ekuberekwa; uye 18% inoshanda muvakuru vane makore makumi masere zvichikwira.
Mutapi wako wezvehutano angangokurudzira Shingrix pamusoro peZostavax. Shingrix inonyanya kukurudzirwa kune varwere vasina immunocompromised sezvo iri isiri yekurarama mushonga. Kumbira chiremba wako kana wemishonga nezve iyo shingles jekiseni yakakunakira iwe.
Kuvhavha uye mutengo kuenzanisa kweShingrix vs.Zostavax
Kune vanhu vakuru vane makore makumi mashanu zvichikwira, zvirongwa chete ine Medicare Chikamu D kufukidza ichavhara mushonga weShingrix. Zvisinei, panogona kunge paine copay kunyangwe aine Medicare Chikamu D kufukidzwa. Ivhareji yemari yemutengo weimwe Shingrix dhizeti iri $ 167, kunyange iwe uchikwanisa kushandisa mushonga wekutora kadhi kudzikisa mutengo uyu. Tarisa nekemikari yako yemuno kuti uone kana uchikwanisa kushandisa kadhi yeShingrix SingleCare.
SaShingrix, Zostavax inonyanya kufukidzwa neMedare Chikamu D zvirongwa kana Medicare Advantage zvirongwa neMedare Chikamu D kufukidza. Iyo copay yeZostavax ine inishuwarenzi inogona kusiyana. Nemutengo wepakati wemari we $ 278, Zostavax inogona kudhura neinishuwarenzi. Kushandisa kadhi rekutora rekunyorera Zostavax inogona kudzikisira mutengo uyu.
| Shingrix | Zostavax | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 1 jekiseni (0.5 ml) uyezve imwe jekiseni (0.5 ml) mwedzi miviri kusvika mitanhatu gare gare | 1 jekiseni rimwe chete (0.65 ml) |
| Chaizvoizvo Medicare copay | $ 0– $ 164 | $ 0– $ 237 |
| SingleCare mutengo | $ 155 + | N / A. |
Zvakajairika mhedzisiro yeShingrix vs. Zostavax
Mhedzisiro inowanzoitika yeShingrix uye Zostavax inosanganisira maitiro panzvimbo yejekiseni. Mushure mejekiseni reShingrix kana Zostavax, unogona kurwadziwa, kutsvuka, kana kuzvimba kwakatenderedza jekiseni saiti. Iwe unogona zvakare kunzwa kushushikana kana kuchemerwa kutenderedza nzvimbo yejekiseni.
Zvichienzaniswa neZostavax, Shingrix anonzi akonzeresa kuita kwakawanda kwehurongwa senge kutemwa nemusoro, kupisa muviri, kurwadziwa kwemhasuru (myalgia), uye kuneta. Nepo iyi mhedzisiro inogona kunetsa, ivo vanowanzo nyoro uye vanonyangarika vega.
| Shingrix | Zostavax | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kutsvuka panzvimbo yejojo | Ehe | 39% | Ehe | 36% |
| Marwadzo panzvimbo yejojo | Ehe | 86% | Ehe | 3. 4% |
| Kuzvimba panzvimbo yejojo | Ehe | 29% | Ehe | 26% |
| Itching panzvimbo jekiseni | Ehe | piri% | Ehe | 7% |
| Kutemwa nemusoro | Ehe | Zvina. Zvishanu | Ehe | 1% |
| Kupindwa nechando | Ehe | 26% | Ehe | piri% |
| Kutambudzika kwemhasuru | Ehe | 53% | Kwete | * |
| Kuneta | Ehe | 51% | Kwete | * |
* haina kutaurwa
Kakawanda hakubvi pane data kubva kumusoro-kuenda-kumusoro kutongwa. Izvi zvinogona kunge zvisiri runyorwa ruzere rwemhedzisiro mhedzisiro inogona kuitika. Ndokumbira utarise kuna chiremba wako kana mupi wezvehutano kuti udzidze zvimwe.
Kunobva: DailyMed (Shingrix) , DailyMed (Zostavax)
Kubatana kwezvinodhaka zveShingrix vs. Zostavax
Immunosuppressive zvinodhaka zvakadai se cyclosporine uye tacrolimus zvinogona kudzikisira kushanda kwemishonga. Steroid, senge prednisone, uye chemotherapy inogona zvakare kuve nematanho ekuzvidzivirira anogona kushandura majekiseni.
Avo vari pamushonga unodzivirira muviri vanofanirwa kunzvenga Zostavax zvachose; Zostavax ine hutachiona hwehupenyu, hunogona kukonzera hutachiona.
Mishonga yeAntiviral yakadai seacyclovir uye famciclovir inogona kukanganisa mhedzisiro yechirwere cheZostavax. Advisory Committee on Immunization Practices (ACIP) inokurudzira kuti vanhu vari pamushonga wehutachiona varege kumwa mishonga yemaantiviral. Maawa makumi maviri nemana zvisati zvaitika kuwana mushonga weZostavax. Kurapa nemishonga inorwisa hutachiona haifanire kutangwazve kwemazuva gumi nemana mushure mekudzivirira neZostavax.
| Zvinodhaka | Kirasi Yezvinodhaka | Shingrix | Zostavax |
| Cyclosporine Tacrolimus Prednisone Chemotherapy | Immunosuppressive kurapwa | Ehe | Ehe |
| Acyclovir Valacyclovir Famciclovir | Antiviral vamiririri | Kwete | Ehe |
Bvunza nyanzvi yezvehutano kune kumwe kudyidzana kwezvinodhaka
Yambiro dzeShingrix naZostavax
Shingrix naZostavax zvinogona kukonzera hypersensitivity, kana allergic, maitiro mune avo vane allergies kuzvidzivirira zvigadzirwa. Zostavax inogona kukonzera kukanganiswa kwakanyanya kune avo vane allergies inozivikanwa kune gelatin kana neomycin. Kuwedzera kweanogadzirisa maitiro kunogona kutungamira kukurumidza kupenga uye kunetseka kufema (anaphylaxis).
Zostavax inofanira kudzivirirwa kune avo vanotora zvinodzivirira uye avo vanokanganiswa nemamiriro ekurapa anoderedza immune system.
Kumbira chiremba wako kana wemishonga nezve zvimwe zvekuchengetedza usati wawana mushonga we shingles.
Inowanzo bvunzwa mibvunzo nezve Shingrix vs. Zostavax
Chii chinonzi Shingrix?
Shingrix ndeye mushonga unogadzirisazve yaishandiswa kudzivirira herpes zoster, kana shingles, muvanhu vakuru vane makore makumi mashanu kana kupfuura. Yakagamuchirwa muna2017, Shingrix mushonga usingashandiswe uyo usina iyo inorarama varicella-zoster hutachiona. Inotarisirwa muzvikamu zviviri zvine mwedzi miviri kusvika mitanhatu pakati peyero yekutanga uye wechipiri dosi. Shingrix inogadzirwa naGlaxoSmithKline.
Chii chinonzi Zostavax?
Zostavax inorarama inodzivirirwa zoster jekiseni raive FDA rakagamuchirwa muna 2006. Semushonga unorarama wakadzivirirwa, Zostavax ine inorarama, isina simba vhezheni yevaricella-zoster hutachiona. Zostavax inoshandiswa mune imwe chete muvanhu vakuru vane makore makumi mashanu kana kupfuura. Iyo inogadzirwa naMerck.
Shingrix naZostavax zvakafanana here?
Ose maviri Shingrix uye Zostavax anogona kudzora njodzi ye shingles. Nekudaro, ivo vanosiyana mukubudirira, manejimendi, uye mhedzisiro. Shingrix mushonga unodzokorodza zoster uye Zostavax mushonga unorarama. Zvinoreva, Shingrix ine fomu isingamisirwe yevaricella-zoster hutachiona uye Zostavax ine inorarama, isina simba fomu yehutachiona. Mumwe mutsauko ndewekuti Shingrix inorowa mumhasuru nepo Zostavax iri kujowa pasi peganda. Kuenzaniswa neZostavax, Shingrix mushonga mutsva we shingles.
Shingrix kana Zostavax zvirinani here?
Shingrix inoshanda kupfuura Zostavax. Shingrix ine 97% inoshanda pakudzivirira shingles muvakuru vane makore makumi mashanu kusvika makumi matanhatu nemapfumbamwe ekuberekwa asi Zostavax inongova 70% inoshanda mukudzivirira shingles mune rimwe zera boka. Shingrix inogara ichidzivirira shingles kune vakura vakuru nepo kushanda kweZostavax kuchiderera nekuwedzera zera. Nekudaro, Shingrix ine yakawanda systemic mhedzisiro kupfuura Zostavax.
Ndinogona here kushandisa Shingrix kana Zostavax ndichiri nepamuviri?
ICentral for Disease Control and Prevention (CDC) haina kukurudzira Shingrix kana Zostavax mune vakadzi vane nhumbu. Iko hakuna zvakakwana zvidzidzo kuti uone iyo kuchengetedzwa kweShingrix kana Zostavax mune vakadzi vane nhumbu . Bvunza chiremba wako kana mupi wezvehutano usati wawana jekiseni re shingles.
Ndinogona here kushandisa Shingrix kana Zostavax nedoro?
Kunwa doro hakuchinje kushanda kweShingrix kana Zostavax. Zvinowanzo chengeteka kunwa zvine mwero mushure mekubaiwa jekiseni nemushonga we shingles.
Mushonga weShingrix unotora nguva yakareba sei?
Kliniki miedzo yakaratidza kuti Shingrix inoramba ichishanda kweanosvika makore mana mushure mechipiri chipimo chemushonga. Zvinokurudzirwa kuti Shingrix inotora kunyange yakatopfuura ipapo. Zvakadaro, zvimwe zvidzidzo zviri kuitiswa mukushanda kweShingrix kwenguva refu.
Inguva yakareba sei Zostavax inoshanda?
Kudzivirirwa kubva kune shingles kunogara kwakatenderedza makore mashanu mushure mekudzivirira neZostavax . Mushure memakore mashanu, kushanda kweZostavax kunogona kuderera nekufamba kwenguva. ICDC inokurudzira kuwana mushonga mutsva we shingles, Shingrix, kunyangwe iwe watogamuchira mushonga weZostavax munguva yakapfuura.
Chii chinoitika kana iwe ukasawana chechipiri Shingrix kupfura?
Yechipiri Shingrix kupfura kwakakosha kuve nechokwadi chekuchengetedzwa kwakazara nemushonga. Nekudaro, iwe haufanire kunetseka kana kwapfuura mwedzi mitanhatu usati wagamuchira booster kupfura. Ingo ita shuwa kuti iwe unogamuchira kechipiri kupfura padhuze nemaviri kusvika matanhatu mwedzi yenguva yenguva sezvazvinogona.
