Prednisolone vs. prednisone: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Prednisolone uye prednisone imwe neimwe inogadzira glucocorticoids inoshandiswa mumatambudziko akasiyana siyana anosanganisira kuzvimba uye autoimmune maitiro. Prednisolone ndiyo inoshanda metabolite ye prednisone. Prednisone inogadzirwa muchiropa kuenda kune prednisolone iyo inokwanisa kuyambuka membrane yesero. Kamwe mukati mechitokisi, prednisolone ine hukama hwakanyanya hwecytoplasmic receptors, uye nekusunga, inodzivirira mapuroteni synthesis. Pakupedzisira, iyo steroid's yakanangwa chiito ndechekudzivirira kweiyo leukocyte kupinda panzvimbo yekuzvimba, kupindira mukushanda kwevamiririri vekupindura kwekupemha, uye kudzvinyirira kweye humoral mhinduro.
Ndeupi musiyano mukuru pakati pe prednisolone uye prednisone?
Prednisolone mushonga wekurapa unoshandiswa mukushushikana uye autoimmune kusagadzikana. Iyo inoshanda metabolite ye prednisone. Kana ichinge yayambuka membrane yesero, inodzivirira kupindira kweanopisa uye ekudzivirira ekudzivirira mamaki.
Prednisolone inogona zvakare kudaidzwa nevamwe mazita ezita rezita senge Prelone, Pediapred, Millipred, Orapred ODT, kana Pred-Forte. Prednisolone inowanikwa mune ophthalmic madonhwe (kuturika uye mhinduro) uye jekiseni mhinduro. Mafomu emuromo anosanganisira mhinduro uye kusimudzira mune 5 mg / ml, 10 mg / ml, uye 15 mg / ml kusangana. Prednisolone inowanikwawo mu5 mg mapiritsi emuromo, pamwe nemapiritsi anoparadzira nemuromo mu10 mg, 15 mg, uye 30 mg simba.
Prednisone imishonga yekunyorera iyo inoshandiswawo mumhando dzakasiyana dzekuputira uye immune immune. Prednisone inogadzirwa necortisone uye inofanirwa kuve inochinjika nechiropa muchimiro chayo chinoshanda, prednisolone, kuitira kuyambuka membrane yesero.
Prednisone inogona zvakare kudaidzwa nemazita ayo ezita Deltasone kana Rayos. Inowanikwa mune 2.5 mg, 5 mg, 10 mg, 20 mg, uye 50 mg mapiritsi emuromo. Inowanikwawo mune mhinduro yemumuromo.
| Misiyano mikuru pakati pe prednisolone uye prednisone | ||
|---|---|---|
| Prednisolone | Prednisone | |
| Kirasi yemishonga | Synthetic glucocorticoid / corticosteroid | Synthetic glucocorticoid / corticosteroid |
| Brand / generic chinzvimbo | Brand uye generic inowanikwa | Brand uye generic inowanikwa |
| Chii chinonzi zita rechiratidzo? | Prelone, Millipred, Orapred ODT, kana Pred-Forte | Deltasone, Mwaranzi |
| Ndeapi mafomu (s) ayo mushonga unouya? | Ophthalmic anodonhedza, jekiseni mhinduro, yemumuromo mhinduro uye kumiswa, yemumuromo uye nemuromo inoparadzanisa mapiritsi | Piritsi yemuromo, mhinduro yemumuromo |
| Ndeipi muyero wakajairwa? | 40 mg kusvika 60 mg yakazara yezuva nezuva dhosi inowanzo kuve yakakamurwa kuita 2 doses | Chekutanga muyero we5 mg kusvika 60 mg ine titration zvichibva pakupindura uye kuongororwa |
| Inguva yakareba sei kurapwa kwacho? | Mazuva matatu kusvika gumi kana kupfuura zvichienderana nekuongororwa | Mazuva mashanu kusvika kumavhiki akati wandei kana kupfuura zvichienderana nekuongororwa. |
| Ndiani anowanzoshandisa mushonga? | Vacheche, vana, uye vakuru | Vacheche, vana, uye vakuru |
Unoda akanakisa mutengo pane prednisolone?
Saina for prednisolone mutengo chenjedzo uye uwane kuti kana mutengo wachinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu anorapwa ne prednisolone uye prednisone
Prednisolone inoshandiswa kurapa akasiyana siyana ehutachiona uye autoimmune kusagadzikana. Izvi zvinosanganisira rheumatic, kufema, allergic, endocrine, collagen, hematologic, gastrointestinal, uye ophthalmic kusagadzikana. Prednisone inogadziriswa kuti ive prednisolone, nekudaro, runyorwa rwayo rwezvinangwa zvekurapa zvakaenzana.
Aya corticosteroids akave anoratidzwa anoshanda mumwaka wegoregic rhinitis, allergic reaction, uye bronchial asthma, zvichibatsira kudzora mweya kuzvimba uye kurerutsa nzira yekufema. Prednisolone uye prednisone zvinoshandawo muanorgic corneal marginal ulcers, herpes zoster ophthalmicus, uye anterior segment kuzvimba kweziso. Prednisolone's topical ophthalmic gadziriro inogona kuratidza kunyanya kubatsira mumatambudziko eziso.
Iyi tafura inotevera, nepo yakazara, inogona kusanyora kushandiswa kwese kwemishonga iyi miviri. Ndokumbira ubvunze nemubatsiri wako wezvehutano kuti uwane rumwe ruzivo nezve zvinoratidza kushandiswa.
| Mamiriro | Prednisolone | Prednisone |
| Kuberekwa adrenal hyperplasia | Ehe | Ehe |
| Nonsuppurative thyroiditis | Ehe | Ehe |
| Rheumatoid arthritis | Ehe | Ehe |
| Ankylosing spondylitis | Ehe | Ehe |
| Yakanaka bursitis | Ehe | Ehe |
| Synovitis yeosteoarthritis | Ehe | Ehe |
| Psoriatic arthritis | Ehe | Ehe |
| Systemic lupus erythematosus | Ehe | Ehe |
| Yakakomba seborrheic dermatitis | Ehe | Ehe |
| Yakanyanya psoriasis | Ehe | Ehe |
| Optic neuritis | Ehe | Ehe |
| Allergic corneal marginal maronda | Ehe | Ehe |
| Herpes zoster ophthalmicus | Ehe | Ehe |
| Anterior chikamu kuzvimba | Ehe | Ehe |
| Allergic conjunctivitis | Ehe | Ehe |
| Zviratidzo sarcoidosis | Ehe | Ehe |
| Aspiration pneumonitis | Ehe | Ehe |
| Idiopathic thrombocytopenic purpura | Ehe | Ehe |
| Ulcerative colitis | Ehe | Ehe |
| Kuwedzera kwakanyanya kweMultiple Sclerosis | Ehe | Ehe |
Is prednisolone kana prednisone inoshanda here?
Kana tichienzanisa kushanda kwe prednisolone uye prednisone, zvakakosha kuyeuka kuti prednisone ndiyo inotungamira kune inoshanda metabolite, prednisolone. Kana uchiongorora kushanda kwechimwe chinodhaka, chekutanga uye chakakosha kufunga kugona kwemurwere kushandura prednisone kune yayo inoshanda metabolite. Prednisone inogadziriswa muchiropa kune prednisolone, uye kumhanya uye kukura kwekushanduka kunoenderana nehepatic function.
Vatsvakurudzi zvichienzaniswa iko kushandurwa kwe prednisone mune varwere vakaratidza kuora hutachiona kune varwere vane zvakajairika chiropa basa. Iko plasma yevasungwa ye prednisolone yaisarudzika musiyano muvarwere vane hepatic chirwere, nevamwe varwere vachiratidza kusatombo shanduka mushonga. Vatsvakurudzi vakagumisa kuti paive nekusiyana kukuru kwekushandurwa kwe prednisone, uye nekudaro varwere vane chirwere chehepatic vangangotadza kushandura prednisone kune yavo inoshanda metabolite.
Varwere vane hutano hwakanaka hwechiropa basa vangatarisira kuti chero prednisolone kana prednisone inoshanda. Prednisolone inofananidzwa ne prednisone pane mg kusvika mg mg. Prednisone inowanikwa mumapiritsi epamusoro, zvichiita kuti kuiswa kwemadhosi epamusoro kuve kwakaomarara. Prednisolone mafomati angafarirwa mune mumwe munhu ane hurema hwechiropa basa kuti abvise kunetseka pamusoro pekutendeuka kwe prednisone.
Unoda mutengo wakanakisa pane prednisone?
Saina kuti uwane prednisone mitengo yambiro uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Kuvhavha uye mutengo kuenzanisa kwe prednisolone vs. prednisone
Prednisolone imushonga yemishonga inowanzo kuvharwa nezvirongwa zvekutengesa uye zveMedicare. Wepakati mutengo wekutengesa we prednisolone 15 mg / 5ml inogona kudarika $ 36 kwemasere maunzii emvura. Nekoponi kubva kuSingleCare, uyu mutengo unodonha kusvika kudzikira kunge $ 27.85.
Prednisone zvakare iri mishonga yemishonga inowanzo kuvharwa nezvose zviri zviviri zvekutangisa inishuwarenzi zvirongwa uye Medicare. Wepakati mutengo wekutengesa we prednisone wakakomberedza $ 22 pamapiritsi gumi e20 mg. Iwe unogona kukwanisa kuwana uyu mushonga wepasi pemadhora mana nekamwe kadhi coupon.
Izvo zvakakosha kuti uzive kuti kune zvimwe zvirwere zvirevo, corticosteroids inogona kunge isingavharirwe pasi peMedicare mushonga wekubatsira, asi inogona kuvharwa pasi peMedare Chikamu B. Mufemesi wako anogona kupa rumwe ruzivo nezve kufukidzwa.
| Prednisolone | Prednisone | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare? | Ehe | Ehe |
| Standard muyero | 8oz, 10 mg / ml mvura | 10, 20 mg mahwendefa |
| Chaizvoizvo Medicare copay | Zvinosiyana zvichienderana nekuumbwa uye kuronga | Kazhinji<$10 but may vary depending on the plan |
| SingleCare mutengo | $ 340- $ 500 | $ 4- $ 6 |
Zvakajairika mhedzisiro mhedzisiro ye prednisolone vs. prednisone
Prednisone inogadziriswa kune yayo inoshanda metabolite prednisolone nechiropa, nekudaro izvo zvinogona kuve mhedzisiro mhedzisiro yemushonga wega wega zvinonamirana.
Glucocorticoids inozivikanwa kuti inokonzera kusaenzana kwemvura uye electrolyte, izvo zvinogona kutungamira mukuchengetwa kwesodium uye fluid, yakakwira BP, uye mune zvimwe zviitiko, congestive moyo kutadza. Kurera huremu kwakajairika mhedzisiro yecorticosteroids.
Kushandiswa kwenguva refu kweSteroid kunogona kunonoka kukura kwevana, uye nekuda kwechikonzero ichi, kushandiswa kwavo kunofanirwa kungogumira kune ipfupi kwenguva yakareba sezvinobvira kuti vawane kuregererwa kwezviratidzo.
Glucocorticoids inogona kukanganisa kupindura kwemuviri kune insulin. Varwere vanovimba neinopinda jekiseni insulin kana mamwe antidiabetic madhiragi vangatofanira kugadzirisa yavo madosi pavanenge vari pasteroid. Vanorwara nechirwere cheshuga vanogona kuona kusimuka mushuga yavo yeropa kunyangwe pane pfupi-pfupi yeyero steroid. Vasiri-cheshuga varwere pane yakareba-kwenguva steroid kurapa kunogona kusvika kanokwana kana mukana wekukura chirwere cheshuga.
Iyi inotevera tafura haina kuitirwa kuti ive yakazara rondedzero yemhedzisiro mhedzisiro mhedzisiro ye prednisone uye prednisolone. Ndokumbirawo ubvunze wemishonga wako kana chiremba kuti uwane rondedzero izere yemhedzisiro.
| Prednisolone | Prednisone | |||
| Side Migumisiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kuchengetwa kwemvura | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Hypertension | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kuchengetwa kwesodium | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kuunganidzwa kwemoyo kukundikana | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kurera huremu | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Tsvina kushaya simba | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Osteoporosis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kutsemuka kwemapfupa marefu | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Peptic ulcer | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Pancreatitis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Abdominal distension | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kukanganiswa kwekupora ronda | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Chiso erythema | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kuwedzera kudikitira | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kutemwa nemusoro | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Vertigo | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Maitiro anochinja | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kukura kudzvinyirira | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Insulin kuramba | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Glaucoma | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
Kunobva: Prednisolone (Mazuva eseMed) Prednisone (Mazuva eseMed)
Kubatana kwezvinodhaka zve prednisolone uye prednisone
Prednisolone uye prednisone ese ari maviri masitepisi eiyo cytochrome P450 enzyme 3A4. Izvi zvinomutsa mukana wekupindirana kwezvinodhaka nekuti yakawanda mimwe mishonga inogadzirwawo neiyo P450 system.
Itraconazole uye ketoconazole zvakajairika antifungal vamiririri. Iwo zvakare ane simba inhibitors eCYP 3A4 enzymes. Iyi mishonga, saka, inononoka metabolism yemushonga unoshanda, prednisolone. Izvi zvinotungamira mukuwedzera serum kuwanda kwe prednisolone. Nepo mishonga ichigona kupihwa pamwechete kwenguva pfupi, varwere vanofanirwa kuongororwa kuti vawedzere mhedzisiro yeglucocorticoid.
Corticosteroids inowanzo shandiswa muvarwere vari zvakare kune mamwe maanosuppressant vamiririri. Mumwe mumiriri anogona kukanganisa zviito zveumwe, asi anogona achiri kushandiswa pamwechete kana akaongororwa zvakakodzera. Semuenzaniso, Prolia (denosumab), inova immunosuppressant uye bone inoshandura mumiririri inoshandiswa mukushushikana kwekuzvidzivirira uye osteoporosis, inogona kuwedzera njodzi yehutachiona hwakakomba kune varwere pane corticosteroids. Kushandiswa kwavo panguva imwe chete dzimwe nguva kunodikanwa, uye varwere vanofanirwa kutariswa zvakanyanya nekuda kwezviratidzo zvehutachiona.
Loop diuretics inobatsira kugadzirisa chinwiwa chemvura mumuviri nekusefa potasium. Kana uchinge wapiwa ne prednisolone kana prednisone, zvisinei, pane mukana wekuti muviri urasikirwe yakawanda potasium. Izvi zvinogona kuve nemhedzisiro pamaitiro emoyo. Varwere vanofanirwa kutora izvi pamwechete vanofanirwa kuve nemamiriro avo e electrolyte anotariswa zvakanyanya.
Iyi tafura inotevera haisi rondedzero yezvose zvingave zvakakomba mhedzisiro. Ndokumbirawo ubvunze wako wekuchengeta hutano kuti uwane yakazara runyorwa.
| Zvinodhaka | Kirasi Yezvinodhaka | Prednisolone | Prednisone |
| Baricitinib Dabrafenib Erdafitinib Ivosidenib Larotrectinib Tofacitinib Upadacitinib | Chiratidzo transduction inhibitors (STI): Immunosuppressants | Ehe | Ehe |
| Denosumab Natalizumab Nivolumab Ocrelizumab Sarilumab Siltuximab | Immunoglobulins: Immunosuppressants | Ehe | Ehe |
| Tacrolimus | Calcineurin inhibitor: Immunosuppressant | Ehe | Ehe |
| Cyclosporine | Cyclic peptide: Immunosuppressant | Ehe | Ehe |
| Aprepitant Fosaprepitant | NK1 mupikisi anopikisa: Anti-nausea | Ehe | Ehe |
| Ketoconazole Itraconazole | Azole antifungals | Ehe | Ehe |
| Desmopressin | Vasopressin analogineni | Ehe | Ehe |
| Diltiazem | Calcium chiteshi blocker | Ehe | Ehe |
| Isoniazid Rifampin | Antitubercular | Ehe | Ehe |
| Phenytoin | Anticonvulsant | Ehe | Ehe |
| Bumetanide Furosemide Torsemide | Loop Diuretics | Ehe | Ehe |
| Aspirin Ibuprofen Naproxen Diclofenac Meloxicam Celecoxib | NSAIDs | Ehe | Ehe |
| Chlorthalidone Hydrochlorothiazide | Thiazide diuretics | Ehe | Ehe |
Yambiro dze prednisolone uye prednisone
Pakave pasina kuongororwa kwakachengetedzwa zvakanaka kwecorticosteroids mune vakadzi vane nhumbu, nekudaro kushandiswa kwavo mukuzvitakura kunofanirwa kuitika chete kana zvave pachena kuti bhenefiti inodarika chero njodzi. Vacheche vakaberekerwa vanaamai vaishandisa corticosteroids panguva yekuzvitakura vanofanirwa kucherechedzwa kune hypoadrenalism. Zviratidzo zvinogona kusanganisira kudya kwakadzika, kurasikirwa uremu, kusagadzikana, uye shuga shoma yeropa.
Corticosteroids, kunyanya muzvikamu zvepamusoro, zvinodzivirira kugona kwemuviri kuburitsa masoja ekudzivirira kana kupihwa majekiseni. Mishonga yekudzivirira zvirwere inogona kusashanda muvarwere vanogamuchira steroid. Urarame majekiseni, senge chibhokisi, haafanire kupihwa kune varwere vari kurapwa corticosteroid kurapwa. Varwere vanotora immunosuppressive vamiririri vari panjodzi yekuwedzera yehutachiona kubva kune chaiwo majekiseni.
Corticosteroids inogona kuvhara zviratidzo zvehutachiona uye inogona kunonoka kuwanikwa kwehutachiona hutsva. Kugara uchishandisa prednisolone uye prednisone kunogona kutungamira kumakata uye glaucoma.
Prednisolone uye prednisone inogona kuchinja mhedzisiro yekuedzwa kweganda kana kumwe kuyedzwa kweanorwara. Kune mhedzisiro yakanyatsoita, steroid kurapa kunofanirwa kumiswa mazuva asati apa bvunzo idzi.
Steroid inongofanirwa kupihwa kwenguva pfupi sezvinobvira kuzadzisa zvaunoda. Kana kushandiswa kwenguva refu kweSteroids kuri kwekurapa kuchidikanwa, vanofanirwa kuchengetwa pane yakaderera inoshanda dosi.
Inowanzo bvunzwa mibvunzo nezve prednisolone vs. prednisone
Chii chinonzi prednisolone?
Prednisolone inogadzirwa glucocorticoid inoshandiswa kurapa kwakasiyana kusagadzikana uye autoimmune kusagadzikana. Inowanikwa sedonhwe reziso, jekiseni remhinduro, mvura yemumuromo, piritsi inonyungudika, uye piritsi remuromo. Nguva yakajairika yekurapwa mazuva matatu kusvika gumi ekurapa kwemuromo.
Chii chinonzi prednisone?
Prednisone iglucocorticoid iyo inogadziriswa nechiropa kune fomu yayo inoshanda, prednisolone. Iyo zvakare inoshandiswa mune dzakawanda kupisa uye autoimmune hosha. Prednisone inowanikwa mumapiritsi emuromo uye nemumuromo mhinduro mafomu. Kushandisa kwakanyanya kwe prednisone kazhinji kune regimen yemazuva mashanu.
Prednisolone uye prednisone zvakafanana here?
Prednisolone uye prednisone ese ari maviri ekugadzira glucocorticoids. Prednisone inogadziriswa muchiropa kune inoshanda metabolite, prednisolone. Simba ravo rekuenzanisa pa milligram hwaro hwakaenzana, asi ivo havana kufanana mushonga.
Is prednisolone kana prednisone zvirinani?
Kunyange madhiragi ese ari maviri achizadzisa iwo maratidziro, prednisolone inogona kunge iri mushonga unodikanwa murwere ane chirwere chisina kukwana chiropa. Varwere vane hepatic chirwere vanogona kusakwanisa kutendeseka kutendeuka prednisone kuita prednisolone.
Ndinogona here kushandisa prednisolone kana prednisone ndichiri nepamuviri?
Prednisolone uye prednisone vane nhumbu nenjodzi chikamu C. Izvi zvinoreva kuti hapana zvinodzorwa zvevanhu zvidzidzo zvinoratidza kuti mushonga wakachengeteka pakuzvitakura. Iyi mishonga inofanirwa kushandiswa chete kana bhenefiti yacho ichidarika njodzi.
Ndinogona here kushandisa prednisolone kana prednisone nedoro?
Kugara uchinwa doro kunogona kukanganisa kugona kwemuviri kugaya prednisone muhunhu hwayo. Doro uye glucocorticoids inogona zvese kuve nemhedzisiro pane iyo gastrointestinal system. Kunwa doro kunonyanya kuderedzwa panguva dzechirapa kurapwa.
Chii chakaenzana ne prednisone?
Prednisolone uye prednisone doses zvakaenzana mumamiligiramu kusvika ku milligram kuenzanisa. Mune mamwe mazwi, 5 mg ye prednisolone yakasimba se5 mg ye prednisone. Prednisolone uye prednisone zvakapetwa kashanu pane hydrocortisone, asi imwe chete-yechitanhatu simba re dexamethasone.
Inguva yakareba sei prednisolone inotora kuti ishandire kuzvimba?
Prednisolone, painopihwa nemuromo, inosvika pakukwirisa kwayo muawa imwe chete kana maviri. Nepo varwere vangangotaura kuzorodzwa kwezviratidzo mumaawa mashoma, zvinogona kutora mazuva maviri kana matatu zviratidzo zvisati zvabatwa zvakanyanya, zvinoenderana nemamiriro uye kuomarara.
Iko prednisone yakaipa kune moyo wako?
Prednisone inozivikanwa kukonzera sodium uye kuchengetedza kwemvura, izvo zvinogona kuwedzera kushushikana pamoyo. Muzviitiko zvakanyanya, zvinogona kutungamira kukundikana kwemoyo kukundikana. Kuburikidza nekubatana kwayo nemishonga yakaita seye furosemide, prednisone inogona kukonzera kurasikirwa kweakawanda e potassium, zvichikonzera murwere kuita hypokalemic. Basa reCardiac rinofanira kuongororwa kana varwere vari pamakwara marefu ekurapa steroid.
