Metoprolol tartrate vs. metoprolol succinate: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Kana iwe wakasangana nekurwadziwa kwemoyo kana parizvino uchirarama neBP yakakwira, chiremba wako anogona kukuraira iwe mushonga senge metoprolol tartrate (Lopressor) kana metoprolol succinate (Toprol XL). Kunyangwe zvese zviri zviviri zvinodhaka zvine zvakafanana zvinoshandiswa zvinoshanda, zvinogona kushandiswa nenzira dzakasiyana.
Ose metoprolol tartrate uye metoprolol anotapira ndeekirasi yemishonga inonzi beta blockers . Ivo dzimwe nguva vanozivikanwawo se beta-1 inosarudza adrenoceptor blockers uye beta vanopikisa.
Iyi mishonga inoshanda nekuvharira mhedzisiro yehormone senge epinephrine uye norepinephrine mune inonzwira tsitsi tsinga system. Tsitsi dzinonzwira tsitsi ndidzo dzinokonzeresa iwo chaiwo maitiro ekurwa-kana-kutiza. Metoprolol inogona kubatsira kudzikisira kushushikana pamoyo, kuzorodza tsinga dzeropa kudzikisa BP, uye kudzikamisa kurwadziwa kwepfupa.
Ndeupi mutsauko mukuru pakati metoprolol tartrate uye metoprolol succinate?
Musiyano mukuru pakati metoprolol tartrate (Chii chinonzi metoprolol tartrate?) Uye metoprolol succinate (Chii chinonzi metoprolol succinate?) Iri mune yavo mafomati. Metoprolol tartrate ndiyo yekukurumidza-kuburitsa vhezheni ye metoprolol nepo metoprolol inotapira iri yakawedzerwa-kuburitsa vhezheni. Izvi zvinoreva kuti metoprolol succinate inoburitswa nekufamba kwenguva mumuviri zvinotungamira mukuita kwenguva refu.
Metoprolol tartrate ingangoda kutorwa kakawanda pazuva. Metoprolol succinate inogona kutorwa kamwe zuva nezuva nekuti inogara kwenguva yakareba kupfuura fomu yetartrate. Metoprolol succinate inogona zvakare kushandiswa muvana vane makore matanhatu nemakore zvichikwira nepo metoprolol tartrate inogona kungoshandiswa muvakuru.
| Misiyano mikuru pakati pemetoprolol tartrate uye metoprolol inotapira | ||
|---|---|---|
| Metoprolol Tartrate | Metoprolol Succinate | |
| Kirasi yemishonga | Beta blocker | Beta blocker |
| Brand / generic chinzvimbo | Brand uye generic vhezheni iripo | Brand uye generic vhezheni iripo |
| Chii chinonzi zita rechiratidzo? | Lopressor | Toprol XL |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa remuromo | Oral piritsi, yakawedzerwa-kusunungurwa |
| Ndeipi muyero wakajairwa? | 100 mg kusvika 400 mg zuva nezuva muzvikamu zvakapatsanurwa | 100 mg kamwe pazuva |
| Inguva yakareba sei kurapwa kwacho? | Ipfupi-temu kana -refu-kushandiswa sekurairwa nachiremba | Ipfupi-temu kana -refu-kushandiswa sekurairwa nachiremba |
| Ndiani anowanzoshandisa mushonga? | Vakuru | Vakuru nevana makore matanhatu zvichikwira |
Unoda akanakisa mutengo pane metoprolol tartrate?
Saina kune metoprolol tartrate mutengo machenjedzo uye uwane kuti kana mutengo wachinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu anorapwa ne metoprolol tartrate uye metoprolol succinate
Iyo tartrate uye succinate mafomu emetoprolol ari FDA-anotenderwa kurapa yakakwira BP (hypertension) uye kurwadziwa kwepfupa (angina pectoris).
Metoprolol tartrate zvakare FDA-inogamuchirwa senzira yekurapa mushure me kumira kurova kwemoyo (yakanyanya myocardial infarction). Kutora metoprolol tartrate mushure mekurwadziwa kwemoyo kunogona kubatsira kudzikisa njodzi yekuenderera mberi kwezviitiko zvemoyo uye kufa kunyanya kune avo vane chirwere checoronary arteri. Kurapa kunowanzo kutanga mukati memazuva matatu kusvika kugumi mushure mekurwadziwa kwemoyo.
Pamusoro pekuwedzera kweropa uye kurwadziwa pachipfuva, metoprolol inotapira zvakare FDA-inogamuchirwa kurapa congestive moyo kutadza . Kunyanya zvakanyanya, metoprolol inotapira inobata kusingaperi kwemoyo kukundikana izvo New York Mwoyo Sangano kirasi II kana III. Yakapihwa seyero yezuva nezuva, metoprolol succinate inogona kugadzirisa mhedzisiro uye kudzikisa njodzi yekufa muvarwere vekutadza kwemoyo.
Kunze-chitaridzi inoshandisa metoprolol inosanganisira supraventricular tachycardia (isina kujairika kukurumidza kurova kwemoyo) uye dutu redziviriro (mamiriro ane njodzi anokonzerwa nekuwedzeredza kwehomoni yehomoni). Zvimwe zvisiri zvekushandisa zvinogona kusanganisira kurapwa kweasina kujairika moyo mutinhimira (arrhythmia) uye kushanda kunetseka .
| Mamiriro | Metoprolol Tartrate | Metoprolol Succinate |
| Kuwedzera kweropa | Ehe | Ehe |
| Kusingaperi kurwadziwa kwepfupa | Ehe | Ehe |
| Kurwara kwemoyo kwakanyanya | Ehe | Kunze-chitaridzi |
| Kutadza kwemoyo | Kunze-chitaridzi | Ehe |
| Supraventricular tachycardia | Kunze-chitaridzi | Kunze-chitaridzi |
| Thyroid dutu | Kunze-chitaridzi | Kunze-chitaridzi |
| Arrhythmia | Kunze-chitaridzi | Kunze-chitaridzi |
| Kuita kunetseka | Kunze-chitaridzi | Kunze-chitaridzi |
Ko metoprolol tartrate kana metoprolol inotapira zvakanyanya?
Metoprolol tartrate uye metoprolol succinate zvese zvakafanana mukubata kwekurapa yakakwira BP uye kusingaperi kurwadziwa kwepfupa. Zvisinei, metoprolol tartrate inogona kushanda zvakanyanya sekurapa kwekurwadziwa kwemoyo kwakanyanya apo metoprolol succinate inogona kushanda zvakanyanya sekurapa kwekusingaperi kwemoyo kutadza.
Clinical miedzo vakaratidza kuti metoprolol tartrate inoshanda pakukwira kweropa uye kudzivirira mhedzisiro yakaipa mushure mekurwadziwa kwemoyo. Pane zvinopesana, zvidzidzo zvinosanganisira iyo Merit-HF kuyedza ndaratidza iyo metoprolol inotapira iri nani pane metoprolol tartrate yekusingaperi kwemoyo kutadza.
Metoprolol succinate inogona kudzokorodza kushanya kwechipatara nekufa kubva mukushaya kwemoyo. Zvisinei, carvedilol , imwe yakajairika beta blocker, inogona kunge ichinyanya kushanda kupfuura metoprolol succinate, sekuyedza kwakaburitswa mu Lancet .
Nekuti metoprolol tartrate inotorwa kakati wandei mukati mezuva, huwandu hwezvinodhaka mumuviri hunogona kunge husingaenderane. Izvi zvinogona kukonzeresa kumimwe mhedzisiro uye kushomeka kushoma kana zvichienzaniswa neyakawedzerwa-kuburitsa succinate fomu. Poshi kuongorora akawana kuti mhedzisiro senge inononoka kurova kwemoyo (bradycardia) inogona kuve inogona kuitika nekukurumidza-kuburitsa metoprolol tartrate.
Kuvhavha uye mutengo kuenzanisa kwemetoprolol tartrate vs. metoprolol succinate
Metoprolol tartrate inogona kutengwa seyakajairwa mushonga mushonga uyo unowanzo kuvharwa neMedare uye nezvimwe zvirongwa zveinishuwarenzi. Pasina inishuwarenzi, avhareji mari yemutengo wegeneric metoprolol tartrate iri madhora mashanu. SingleCare makadhi ekuderedzwa anogona kushandiswa kumafarmacy anotora chikamu kudzikisa mutengo wechirwere ichi. Unogona kuwana mutengo padyo ne $ 4 nekaponi yekuchengetedza.
Metoprolol inotapira kana yakawedzerwa-kuburitsa metoprolol inowanikwa semushonga wakajairika wakafukidzwa nemazhinji maMedare uye zvirongwa zveinishuwarenzi. Generic metoprolol succinate inowanzo kuve yakavharwa kupfuura iyo zita rezita Toprol XL. Wepakati mutengo wekutengesa we generic Toprol XL iri kutenderera $ 56. Tarisa neyefamasi yako kuti uone kana iwe uchigona kusevha yakawanda neiyo SingleCare yekuchengetedza kadhi. Kana ichigamuchirwa, unogona kudzikisa mutengo kusvika pa $ 9.
| Metoprolol Tartrate | Metoprolol Succinate | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare? | Ehe | Ehe |
| Standard muyero | 50 mg mahwendefa | 100 mg mapiritsi |
| Chaizvoizvo Medicare copay | $ 0- $ 65 | $ 0- $ 20 |
| SingleCare mutengo | $ 4 | $ 9 |
Tora kadhi rekudzikisira chemishonga
Zvakajairika mhedzisiro mhedzisiro yemetoprolol tartrate vs. metoprolol inotapira
Metoprolol tartrate uye metoprolol succinate inogona kukonzera mhedzisiro yakafanana. Mhedzisiro inowanzoitika yemetoprolol inosanganisira kuneta kana kuneta, dzungu, kushushikana, kufema kwekufema (dyspnea), uye inononoka kurova kwemoyo (bradycardia). Zvimwe zvinokonzeresa zvinosanganisira manyoka, kusvotwa, kurutsa, uye kuoma mukanwa.
Hypersensitivity reaction sekumhanyisa kana kuchenesa kunogona kuitika kana uchitora chero fomu metoprolol. Kubva pane iyo FDA chitaridzi , metoprolol tartrate inogona kunge ichikonzera mimwe mhedzisiro.
| Metoprolol Tartrate | Metoprolol Succinate | |||
| Side Migumisiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kuneta | Ehe | 10% | Ehe | > 2% |
| Dzungu | Ehe | 10% | Ehe | > 2% |
| Mapundu | Ehe | 5% | Ehe | > 2% |
| Kushungurudzika | Ehe | 5% | Ehe | > 2% |
| Manyoka | Ehe | 5% | Ehe | > 2% |
| Kufema kwekufema | Ehe | 3% | Ehe | > 2% |
| Kunonoka kurova kwemoyo | Ehe | 3% | Ehe | > 2% |
| Muromo wakaoma | Ehe | 1% | Ehe | * haina kutaurwa |
| Nausea | Ehe | 1% | Ehe | * |
| Kushungurudza | Ehe | 1% | Ehe | * |
| Kuzvimbirwa | Ehe | 1% | Ehe | * |
Iri rinogona kunge risiri runyorwa rwakakwana. Bvunza chiremba wako kana wemishonga kuti uwane mhedzisiro.
Kunobva: Mazuva eseMed (metoprolol tartrate) , DailyMed (metoprolol inotapira)
Kubatana kwezvinodhaka kwemetoprolol tartrate vs. metoprolol succinate
Metoprolol tartrate uye metoprolol succinate inogona kusangana nemazhinji emimwe mishonga. Mimwe mishonga ine zviito zvakafanana kana kukanganisa metabolism ye beta blockers inogona kusangana nemhando mbiri dze metoprolol.
Metoprolol haifanire kutorwa necatecholamine-inopedza zvinodhaka. Kutora mishonga iyi pamwechete kunogona kuwedzera mhedzisiro ye beta blockers uye kukonzere zviitiko zvakashata senge yakaderera BP. hypotension ) uye inononoka kurova kwemoyo (bradycardia). Mimwe mhedzisiro yakaipa inogona kusanganisira dzungu nekufenda.
Metoprolol inogadziriswa zvakanyanya neCYP2D6 enzyme. Naizvozvo, zvinodhaka zvinodzivisa iyi enzyme zvinogona kukonzera kuwedzera metoprolol mazinga mumuviri. Kuwedzera metoprolol mazinga anogona kuwedzera njodzi yemhedzisiro.
Digoxin nemishonga inonzi calcium chiteshi blockers inogona kuve neinowedzera mhedzisiro painopihwa ne metoprolol. Kutora chero eaya madhiragi ne metoprolol kunogona kukonzera mhedzisiro mumoyo.
| Zvinodhaka | Kirasi Yezvinodhaka | Metoprolol Tartrate | Metoprolol Succinate |
| Reserpine Tetrabenazine | Catecholamine-inopedza mishonga | Ehe | Ehe |
| Quinidine Fluoxetine Fluvoxamine Sertraline Bupropion Paroxetine Propafenone Haloperidol Diphenhydramine Hydroxychloroquine Terbinafine | CYP2D6 inhibitor | Ehe | Ehe |
| Digoxin | Cardiac glycoside | Ehe | Ehe |
| Diltiazem Verapamil | Calcium chiteshi blocker | Ehe | Ehe |
| Clonidine Guanethidine Betanidine | Alpha-adrenergic mumiriri | Ehe | Ehe |
Izvi zvinogona kunge zvisiri rondedzero izere yezvinobvira kudyidzana kwezvinodhaka. Bvunza chiremba nemishonga yose yaungave uri kutora.
Yambiro dze metoprolol tartrate uye metoprolol succinate
Ose metoprolol tartrate uye metoprolol succinate haifanire kumiswa nekukasira. Kana kurapwa ne metoprolol kukamiswa nekukasira, vamwe vanhu vanogona kuwana njodzi yakakwira yekurwara nemoyo, zvisina kujairika moyo mutinhimira , uye kurwadziwa pachipfuva. Ngozi yezviitiko izvi yakakwira kune avo vane chirwere chepfungwa chepasi.
Beta blockers senge metoprolol haifanire kushandiswa mune chero munhu ane anotevera mamiriro:
- Yakanyanya bradycardia
- Moyo unovharira wakakura kupfuura wekutanga degree
- Cardiogenic kuvhunduka
- Yakadzora moyo kutadza
- Sick sinus syndrome isina pacemaker
- Hypersensitivity kune chero zvigadzirwa mumishonga iyi
Bvunza chiremba kuti uone kana iwe ungave uine chero eaya mamiriro usati watanga kurapwa.
Beta blockers anogona kuvhara zviratidzo nezviratidzo zve hypoglycemia, kana yakaderera ropa shuga. Vaya vane chirwere cheshuga vangangoda kuongorora shuga yavo yeropa vachitora beta blockers.
Inowanzo bvunzwa mibvunzo nezve metoprolol tartrate vs. metoprolol succinate
Chii chinonzi metoprolol tartrate?
Metoprolol tartrate izita rakajairika reLopressor. Iyo beta blocker inoshandiswa kurapa kukwirisa kweropa uye kusingaperi kurwadziwa kwepfupa. Inotenderwawo kurapwa kweacute heart attack kudzikisira njodzi yekufa.
Chii chinonzi metoprolol succinate?
Metoprolol succinate inozivikanwa zvakare nezita rezita rinonzi Toprol XL. Iyo ndiyo yakawedzerwa-kuburitsa fomu yemetoprolol. Metoprolol succinate inogamuchirwa kurapa kukwirisa kweropa, kurwadziwa kwepachechi kusingaperi, uye congestive kutadza kwemoyo .
Ko metoprolol tartrate uye metoprolol inotapira zvakafanana?
Kwete. Metoprolol tartrate ipiritsi rinoburitsa nekukasira nepo metoprolol inotapira iri yakawedzera-kuburitsa piritsi. Dzinogona kushandiswa nenzira dzakasiyana.
Iko metoprolol tartrate kana metoprolol inotapira zvirinani?
Metoprolol tartrate uye metoprolol succinate zvese zvinoshanda zvichienderana nemamiriro ari kurapwa. Metoprolol succinate inoshanda zvakanyanya pakurapa kutadza kwemoyo. Metoprolol inotapira inogona zvakare kunge isingaite mhedzisiro.
Ndinogona here kushandisa metoprolol tartrate kana metoprolol succinate ndichiri nepamuviri?
Metoprolol inofanira kungoshandiswa chete panguva yekuzvitakura kana mabhenefiti acho achinyanyisa kupfuura njodzi. Hazvina kukwana zvidzidzo zvakaitwa kuratidza kuti iyi mishonga iri 100% yakachengeteka panguva yekuzvitakura. Tsvaga chiremba kana iwe uri nepamuviri kana uchiyamwisa.
Ndinogona here kushandisa metoprolol tartrate kana metoprolol inotapira nedoro?
Kunwa doro uchitora metoprolol kunogona kuwedzera njodzi yekutsimwa uye dzungu. Izvo hazviwanzo kukurudzirwa kushandisa metoprolol ne doro .
Unogona here kushandura kubva metoprolol tartrate uchiita succinate?
Mune zvimwe zviitiko, metoprolol tartrate inogona kuchinjirwa kune metoprolol succinate. Metoprolol succinate inogona kuve yakasarudzika kune yayo kamwe-zuva nezuva dosing. Bvunza chiremba kuti uone nzira dzako dzekurapa kana uchinja mishonga.
Ndeipi nguva yausingafanirwe kutora metoprolol?
Metoprolol haifanire kutorwa kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge waita Izvo zvakakosha kuti ukurukure nhoroondo yako yekurapa nachiremba kuti uone kana uchifanira kunge uri pane metoprolol.
Chii chandinofanira kudzivisa pakutora metoprolol?
Doro uye mimwe mishonga inofanirwa kudzivirirwa uchitora metoprolol. Mimwe mishonga inosanganisira calcium chiteshi blockers, zvimwe mishonga inodzvinyirira , uye izvo zvakagadziriswa nenzira imwecheteyo se metoprolol inogona kuwedzera njodzi yemhedzisiro ine metoprolol.
Ko metoprolol mishonga ine njodzi huru here?
Ehe. Metoprolol inogona kutorwa seyakanyanya njodzi mishonga. Kana ikashandiswa zvisizvo, metoprolol inogona kukonzera kukuvara kukuru.
