Methylprednisolone vs. prednisone: Misiyano, kufanana, uye chii chiri nani
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Methylprednisolone uye prednisone inogadzira glucocorticoids anoshandiswa mumatambudziko akasiyana siyana. Iyi mishonga yakafanana zvikuru nemahomoni anogadzirwa neadrenal gland yemuviri wako. Kana ichiiswa mune yakakwira doses kupfuura yako muviri yaiwanzozvigadzira yega, vanoshanda munzira dzakasiyana siyana kudzvinyirira mamwe maseru ekudzivirira uye ekuzvimba akadai se leukotrienes, prostaglandins, kinins, uye histamines. Iyi nzira yekuita inobvumidza iyi mishonga kuti ibudirire pakurapa zvirwere zvekufema, autoimmune kusagadzikana, uye kusagadzikana kwekuputira, kutumidza mashoma. Kunyange mishonga yese iri miviri ingangoshandiswa mumatambudziko akafanana, pane misiyano pakati pezviviri.
Ndeupi mutsauko mukuru pakati pemethylprednisolone uye prednisone?
Methylprednisolone mushonga unonyorwa unoshandiswa mumhando dzakasiyana dzematambudziko anosanganisira asthma, ulcerative colitis, rheumatoid arthritis, uye allergic reaction. Methylprednisolone inogadzirwa ne prednisolone, uye mashandiro ayo anoita kuti ive inobatsira mune dzakasiyana siyana dzekuputira uye immune immune. Methylprednisolone inoyambuka cellular membrane uye inosunga kune zvinogamuchira izvo zvinotitisa mapuroteni synthesis uye kugadzirwa kwecytokines. Cytokines inoita basa rakakosha mukuvhiringidza. Nenzira imwechete iyi, inomisawo kupindira kweeukotrienes uye mamwe mamaki ekudzivirira immune. Izvi zvinoita kuti mushonga ubudirire sezvose zviri zviviri anti-kuzvimba uye immunosuppressive mumiriri.
Methylprednisolone inowanikwa mu4 mg, 8 mg, 16 mg, uye 32 mg mapiritsi emuromo. Inowanikwawo mumhinduro dzinogona kupihwa seinisira kana jekiseni remutsipa. Iro zita rekuti methylprednisolone mahwendefa ndiMedrol. Methylprednisolone inogona kushandiswa mune vacheche, vana, uye vakuru.
Prednisone imishonga yekunyorera iyo inoshandiswawo mumhando dzakasiyana dzekuputira uye immune immune. Prednisone inogadzirwa necortisone uye inofanirwa kuve inochinjika nechiropa muchimiro chayo chinoshanda, prednisolone, kuitira kuyambuka membrane yesero. Kana ichinge yayambuka membrane, mashandiro ayo akafanana neaya emethylprednisolone mune iyo inodzivirira kupinda mukati kweanopisa uye ekudzivirira ekudzivirira mamaki.
Prednisone inogona zvakare kudaidzwa nezita rayo rekuti Deltasone. Inowanikwa mune 2.5 mg, 5 mg, 10 mg, 20 mg, uye 50 mg mapiritsi emuromo. Inowanikwawo mune mhinduro yemumuromo.
| Misiyano mikuru pakati pemethylprednisolone vs. prednisone | ||
|---|---|---|
| Methylprednisolone | Prednisone | |
| Kirasi yemishonga | Corticosteroid | Corticosteroid |
| Brand / generic chinzvimbo | Brand uye generic inowanikwa | Brand uye generic inowanikwa |
| Chii chinonzi zita rechiratidzo? | Medrol, SoluMedrol | Deltasone |
| Ndeapi mafomu (s) ayo mushonga unouya? | Oral piritsi, Solution yejekiseni | Piritsi yemuromo, mhinduro yemumuromo |
| Ndeipi muyero wakajairwa? | Chekutanga muyero we4 mg kusvika 48 mg ine titration zvichibva pakupindura uye kuongororwa | Chekutanga muyero we5 mg kusvika 60 mg ine titration zvichibva pakupindura uye kuongororwa |
| Inguva yakareba sei kurapwa kwacho? | Mazuva matanhatu kusvika kumavhiki akati wandei kana kupfuura zvichienderana nekuongororwa. | Mazuva mashanu kusvika kumavhiki akati wandei kana kupfuura zvichienderana nekuongororwa. |
| Ndiani anowanzoshandisa mushonga? | Vacheche, vana, uye vakuru | Vacheche, vana, uye vakuru |
Unoda mutengo wakanakisa pane prednisone?
Saina kuti uwane prednisone mitengo yambiro uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu anorapwa ne methylprednisolone vs. prednisone
Methylprednisolone inoshandiswa pakurapa kweakasiyana siyana ehurwere mamiriro uye kusagadzikana. Maitiro ayo pane yekuzvimba maitiro anoita kuti ive inobatsira mune rheumatic kusagadzikana senge rheumatoid uye psoriatic arthritis, spondylitis, uye bursitis. Iyo inoshandiswawo kurapa maronda akaomarara eabronchial asthma. Iyo immunosuppressive zvimiro zve methylprednisolone inoita kuti ive mushonga unoshanda mumamiriro ezvinhu ehurwere senge acute allergic rhinitis, kubata dermatitis, uye kugadzikana kwekunzwa zvinodhaka. Inoshandiswawo mu endocrine, collagen, hematologic, gastrointestinal, uye ophthalmic kusagadzikana.
Prednisone inoshandiswawo kurapa akasiyana siyana ehutachiona uye autoimmune kusagadzikana kwakafanana ne methylprednisolone. Izvi zvinosanganisira rheumatic, kufema, allergic, endocrine, collagen, hematologic, gastrointestinal, uye ophthalmic kusagadzikana.
Iyi tafura inotevera, nepo yakazara, inogona kusanyora kushandiswa kwese kwemishonga iyi miviri. Ndokumbira ubvunze nemubatsiri wako wezvehutano kuti uwane rumwe ruzivo nezve zvinoratidza kushandiswa.
| Mamiriro | Methylprednisolone | Prednisone |
| Kuberekwa adrenal hyperplasia | Ehe | Ehe |
| Nonsuppurative thyroiditis | Ehe | Ehe |
| Rheumatoid arthritis | Ehe | Ehe |
| Ankylosing spondylitis | Ehe | Ehe |
| Yakanaka bursitis | Ehe | Ehe |
| Synovitis yeosteoarthritis | Ehe | Ehe |
| Psoriatic arthritis | Ehe | Ehe |
| Systemic lupus erythematosus | Ehe | Ehe |
| Yakakomba seborrheic dermatitis | Ehe | Ehe |
| Yakanyanya psoriasis | Ehe | Ehe |
| Optic neuritis | Ehe | Ehe |
| Allergic conjunctivitis | Ehe | Ehe |
| Zviratidzo sarcoidosis | Ehe | Ehe |
| Aspiration pneumonitis | Ehe | Ehe |
| Idiopathic thrombocytopenic purpura | Ehe | Ehe |
| Ulcerative colitis | Ehe | Ehe |
| Kuwedzera kwakanyanya kweMultiple Sclerosis | Ehe | Ehe |
Ko methylprednisolone kana prednisone inoshanda zvakanyanya?
Kune nzira dzakawanda dzekuenzanisa methylprednisolone uye prednisone nekuda kwavo kwakawanda kushandiswa. Mune akawanda maitiro ekuzvimba, kurapwa ne corticosteroids kunogumira kune pfupi pfupi kushandiswa mukukomba uye kwakanyanya kuwedzera kwechirwere. Kana tichienzanisa methylprednisolone uye prednisone zvakananga, 4 mg ye methylprednisolone yakaenzana ne5 mg ye prednisone. Nekudaro, kana madosi akagadziriswa uye kuongororwa kuti apindure, yega yega inogona kushanda pakurapa.
Imwe fundo yakatsvaga kuenzanisa iyo mhedzisiro ye intravenous methylprednisolone kumuromo prednisone muacute asthma kuwedzera mune vana. Mapoka maviri ekurapa akasarudzika kuti agamuchire kana 30 mg ye intravenous methylprednisolone kana 30 mg yemuromo prednisone. Mapoka ese ari maviri akagamuchira albuterol, uye vaongorori vakaongorora zororo rezviratidzo, yepamusoro kufema kwekuyerera (PEF), uye kupomba kuverenga oximetry. Kuverengwa kwakatorwa kweboka rega rega pamaawa maviri, mana, uye matanhatu mushure mekutanga kurapwa. Pakange pasina kiriniki kana huwandu hwakakosha musiyano panguva yega yega pakati pemapoka maviri aya. Vatsvakurudzi vakagumisa kuti oral prednisone yaizove sarudzo yepamusoro nekuda kwemutengo wakaderera uye neanoshungurudza manejimendi.
Unoda akanakisa mutengo pane methylprednisolone?
Saina kune methylprednisolone mutengo wekuzivisa uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Kuvhavha uye mutengo kuenzanisa kwemethylprednisolone vs. prednisone
Methylprednisolone mushonga unonyorwa unowanzo kuvharwa nezvirongwa zveinishuwarenzi zvekutengeserana pamwe neMedicare. Kosi yemazuva matanhatu emapiritsi e21 emasimba e4 mg anogona kuita madhora zana ezita rezita. Nekoponi kubva kuSingleCare, unogona kuwana methylprednisolone yakaderera se $ 15.
Prednisone zvakare iri mishonga yemishonga inowanzo kuvharwa nezvose zviri zviviri zvekutangisa inishuwarenzi zvirongwa uye Medicare. Wepakati mutengo wekutengesa we prednisone wakakomberedza $ 22 pamapiritsi gumi e20 mg. Iwe unogona kukwanisa kuwana uyu mushonga wepasi pemadhora mana nekamwe kadhi coupon.
Izvo zvakakosha kuti uzive kuti kune zvimwe zvirwere zvirevo, corticosteroids inogona kunge isingavharidzwe pasi pemishonga yemubatsiro, asi inogona kuvharwa pasi peMedare Chikamu B. Mufemesi wako anogona kupa rumwe ruzivo nezve kufukidzwa.
| Methylprednisolone | Prednisone | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare? | Ehe | Ehe |
| Standard muyero | 21, 4 mg mahwendefa | 10, 20 mg mahwendefa |
| Chaizvoizvo Medicare copay | Kazhinji<$10 but may vary depending on the plan | Kazhinji<$10 but may vary depending on the plan |
| SingleCare mutengo | $ 15 + | $ 4- $ 6 |
Zvakajairika mhedzisiro mhedzisiro yemethylprednisolone uye prednisone
Prednisone inogadziriswa kune yayo inoshanda metabolite prednisolone nechiropa. Prednisolone uye methylprednisolone zvakafanana nemakemikari, uye nekudaro yavo mhedzisiro mhedzisiro vanonamira pamwe.
Glucocorticoids inozivikanwa kuti inokonzera kusaenzana kwemvura uye electrolyte izvo zvinogona kutungamira mukuchengetwa kwesodium uye fluid, yakakwira BP, uye mune zvimwe zviitiko, congestive moyo kutadza. Methylprednisolone uye prednisone zvinogona zvakare kutungamira kukundikana kwemhasuru uye kurasikirwa kwemhasuru. Glucocorticoids inozivikanwa kunge inokanganisa dumbu uye inogona kutungamira mukusvotwa, kurutsa, kana kuzvimba mudumbu. Steroid inogona kunonoka kupora kwemaronda. Kushandiswa kwenguva refu kwemethylprednisolone uye prednisone kunogona kudzora kukura kwevana, uye nekuda kweichi chikonzero, kushandiswa kwavo kunofanirwa kugumira kune ipfupi kwenguva yakareba sezvinobvira kuti vawane kuregererwa kwezviratidzo.
Glucocorticoids inogona kukanganisa mhinduro yemuviri kune insulin. Varwere pane yakareba-kwenguva steroid kurapa vanogona kusvika kanokwana kana mukana wekukura chirwere cheshuga. Varwere vanovimba neinopinda jekiseni insulin kana zvimwe antidiabetic zvinodhaka vangangodaro vachiwedzera mwero wavo pavanenge vari pasteroid. Hazvisi zvisingazivikanwi kune vane chirwere cheshuga chinodzorwa zvakanaka kuti vaone kusimuka kweshuga reropa ravo kunyangwe pane pfupi-pfupi dhizaini yesteroid.
Iyi tafura inotevera haina kuitirwa kuti ive yakazara rondedzero yemhedzisiro. Ndokumbirawo ubvunze wemishonga wako kana chiremba kuti uwane rondedzero izere yemhedzisiro.
| Methylprednisolone | Prednisone | |||
| Kuchengetwa kwesodium | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kuchengetwa kwemvura | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Hypertension | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kuunganidzwa kwemoyo kukundikana | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kurera huremu | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Tsvina kushaya simba | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Osteoporosis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kutsemuka kwemapfupa marefu | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Peptic ulcer | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Pancreatitis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Abdominal distension | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kukanganiswa kwekupora ronda | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Chiso erythema | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kuwedzera kudikitira | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kutemwa nemusoro | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Vertigo | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Maitiro anochinja | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kukura kudzvinyirira | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Insulin kuramba | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Glaucoma | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
Kunobva: Methylprednisolone (Mazuva eseMed) Prednisone (Mazuva eseMed)
Kubatana kwezvinodhaka kwemethylprednisolone uye prednisone
Methylprednisolone uye prednisone ndiwo ega masitendi eiyo cytochrome P450 enzyme 3A4. Iyo P450 enzyme system iri muchiropa ndiyo inokonzeresa metabolism yemishonga yakawanda, uye nekudaro pane mukana wekupindirana kwezvinodhaka.
Corticosteroids inowanzo shandiswa muvarwere vari zvakare kune mamwe maanosuppressant vamiririri. Kudzora kupindurwa kwemuviri mukuisirwa nhengo uye kumwe autoimmune kusagadzikana kunogona kuda kushandiswa kweanopfuura imwechete immunosuppressive mumiriri. Mumwe mumiriri anogona kukanganisa metabolism yemumwe, asi anogona achiri kushandiswa pamwechete kana akaongororwa zvakakodzera. Semuenzaniso, tacrolimus uye cyclosporine ndeimwe inhibitors yeCYP 3A4. Izvi zvinogona kutungamira mukuwedzera serum kuwanda kwemethylprednisolone kana prednisone painoshandiswa pamwechete. Pakave nezviitiko zvekugwinha zvinotaurwa nekushandiswa kunoitwa cyclosporine uye methylprednisolone, asi izvi hazviwanzo.
Loop diuretics inobatsira kugadzirisa chinwiwa chemvura mumuviri nekusefa potasium. Kana uchinge wapiwa ne methylprednisolone kana prednisone, zvisinei, pane mukana wekuti muviri urasikirwe yakawanda potasium. Izvi zvinogona kuve nemhedzisiro pamaitiro emoyo. Varwere vanofanirwa kutora izvi pamwechete vanofanirwa kuve nemamiriro avo e electrolyte anotariswa zvakanyanya.
Iyi inotevera tafura haisi rondedzero yezvose zvingaite mhedzisiro. Ndokumbirawo ubvunze wako wekuchengeta hutano kuti uwane yakazara runyorwa.
| Zvinodhaka | Kirasi Yezvinodhaka | Methylprednisolone | Prednisone |
| Baricitinib Dabrafenib Erdafitinib Ivosidenib Larotrectinib Tofacitinib Upadacitinib | Chiratidzo transduction inhibitors (STI): Immunosuppressants | Ehe | Ehe |
| Denosumab Natalizumab Nivolumab Ocrelizumab Sarilumab Siltuximab | Immunoglobulins: Immunosuppressants | Ehe | Ehe |
| Tacrolimus | Calcineurin inhibitor: Immunosuppressant | Ehe | Ehe |
| Cyclosporine | Cyclic peptide: Immunosuppressant | Ehe | Ehe |
| Aprepitant Fosaprepitant | NK1 mupikisi anopikisa: Anti-nausea | Ehe | Ehe |
| Ketoconazole Itraconazole | Azole antifungals | Ehe | Ehe |
| Desmopressin | Vasopressin analogineni | Ehe | Ehe |
| Diltiazem | Calcium chiteshi blocker | Ehe | Ehe |
| Isoniazid Rifampin | Antitubercular | Ehe | Ehe |
| Phenytoin | Anticonvulsant | Ehe | Ehe |
| Bumetanide Furosemide Torsemide | Loop Diuretics | Ehe | Ehe |
| Aspirin Ibuprofen Naproxen Diclofenac Meloxicam Celecoxib | NSAIDs | Ehe | Ehe |
| Chlorthalidone Hydrochlorothiazide | Thiazide diuretics | Ehe | Ehe |
Yambiro dze methylprednisolone uye prednisone
Corticosteroids inogona kuvhara zviratidzo zvehutachiona uye inogona kunonoka kuwanikwa kwehutachiona hutsva. Kushandiswa kwenguva refu kwemethylprednisolone uye prednisone kunogona kutungamira kumakata uye glaucoma.
Pakave pasina kuongororwa kwakachengetedzwa zvakanaka kwecorticosteroids mune vakadzi vane nhumbu, nekudaro kushandiswa kwavo mukuzvitakura kunofanirwa kuitika chete kana zvave pachena kuti bhenefiti inodarika chero njodzi. Vacheche vakaberekerwa vanaamai vaishandisa corticosteroids panguva yekuzvitakura vanofanirwa kucherechedzwa kune hypoadrenalism.
Corticosteroids, kunyanya muzvikamu zvepamusoro, zvinodzivirira kugona kwemuviri kuburitsa masoja ekudzivirira kana kupihwa majekiseni. Mishonga yekudzivirira zvirwere inogona kusashanda muvarwere vanogamuchira steroid. Urarame majekiseni, senge chibhokisi, haafanire kupihwa kune varwere vari kurapwa corticosteroid kurapwa. Varwere vanotora immunosuppressive vamiririri vari panjodzi yekuwedzera yehutachiona kubva kune chaiwo majekiseni.
Methylprednisolone uye prednisone inogona kuchinja mhedzisiro yekuedzwa kweganda kana kumwe kuyedzwa kweanorwara. Kune mhedzisiro yakanyatsoita, steroid kurapa kunofanirwa kumiswa mazuva asati apa bvunzo idzi.
Steroid inongofanirwa kupihwa kwenguva pfupi sezvinobvira kuzadzisa zvaunoda. Kana kushandiswa kwenguva refu kweSteroids kuri kwekurapa kuchidikanwa, vanofanirwa kuchengetwa pane yakaderera inoshanda dosi.
Inowanzo bvunzwa mibvunzo nezve methylprednisolone vs. prednisone
Chii chinonzi methylprednisolone?
Methylprednisolone inogadzira glucocorticoid inoshandiswa kurapa kwakasiyana kusagadzikana uye autoimmune kusagadzikana. Inowanikwa sehwendefa remuromo uye sejekiseni. Nguva yakajairika yekurapwa mazuva matanhatu ekurapwa nemuromo.
Chii chinonzi prednisone?
Prednisone iglucocorticoid iyo inogadziriswa nechiropa kune fomu yayo inoshanda, prednisolone. Iyo zvakare inoshandiswa mune dzakawanda kupisa uye autoimmune hosha. Prednisone inowanikwa mumapiritsi emuromo uye nemumuromo mhinduro mafomu. Kushandisa kwakanyanya kwe prednisone kazhinji kune regimen yemazuva mashanu.
Methylprednisolone uye prednisone zvakafanana here?
Kunyangwe iwo ari maviri glucocorticoids, methylprednisolone uye prednisone hazvina kunyatsofanana. Prednisone inofanirwa kuve inogadziriswa kune yayo inoshanda fomu, prednisolone, kuitira kuti ive nemhedzisiro mumuviri. Muyero we4 mg yemethylprednisolone yakaenzana ne5 mg prednisone.
Is methylprednisolone kana prednisone zvirinani?
Methylprednisolone uye prednisone imwe neimwe inogona kuwana kuregererwa kwechiratidzo kana madosi avo atangwa zvakakodzera. Mafomu emuromo anogona kuve anodikanwa pamusoro peiyo jekiseni mafomati nekuda kwemutengo wakaderera uye kurerukirwa kwekutonga.
Ndinogona here kushandisa methylprednisolone kana prednisone ndichiri nepamuviri?
Methylprednisolone uye prednisone vane nhumbu nenjodzi chikamu C. Izvi zvinoreva kuti hapana zvinodzorwa zvevanhu zvidzidzo zvinoratidza kuti mushonga wakachengeteka pakuzvitakura. Iyi mishonga inofanirwa kushandiswa chete kana bhenefiti yacho ichidarika njodzi.
Ndinogona here kushandisa methylprednisolone kana prednisone nedoro?
Doro rinogadzirwa nechiropa. Kuramba uchinwa doro kunogona kukanganisa kugona kwemuviri kugadzirisa prednisone muhunhu hwayo. Doro uye glucocorticoids inogona zvese kuve nemhedzisiro pane iyo gastrointestinal system. Kunwa doro kunonyanya kuderedzwa panguva dzechirapa kurapwa.
Methylprednisolone yakasimba steroid?
Ipo methylprednisolone ingangoita makumi maviri muzana zvine simba kupfuura prednisone, inongova chikamu chimwe chete muzvishanu pasimba remamwe maglucocorticoid senge dexamethasone kana betamethasone. Nekudaro, iyo yakapetwa kashanu zvine simba kupfuura hydrocortisone.
Zvinotora nguva yakareba sei kutora methylprednisolone kutanga kushanda? / Methylprednisolone inokurumidza kuita?
Methylprednisolone inokurumidza kutanga. Inosvika pakukwirisa kwayo mukati meawa kana maviri maawa mushure memudhara wemumuromo, uye mukati meawa rimwe chete reropa rinopinza. Inogadziriswa nechiropa kuita isingashandi metabolism iyo inoburitswa mumugini. Hafu-yehupenyu yemethylprednisolone ndeye 18 kusvika kumaawa makumi matanhatu nematanhatu zvinoreva kuti zvinogona kutora mazuva maviri kusvika manomwe kuti ubvise mushonga zvachose kubva mumuviri.
