Crestor vs. Lipitor: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Maererano neCenters for Disease Control and Prevention (CDC), vangangoita 38% yevakuru muU.S. vane cholesterol yakawanda. Kana uine cholesterol yakawanda, chiremba wako anogona kukuraira nezvekukosha kwekudya uye kurovedza muviri. Chiremba wako anogona kunge akataura zvakare kutanga statin mishonga. Statins inozivikanwa mishonga yemishonga, inozivikanwawo seHMG-CoA reductase inhibitors. Ivo vanoshanda nekudzivirira enzyme (inonzi HMG-CoA reductase) iyo muviri wako unoda kugadzira cholesterol.
Crestor uye Lipitor mairi maviri anozivikanwa mazita ezita anoshandiswa kudzikisa cholesterol mwero. Mishonga iyi miviri inogamuchirwa neU.S.Food and Drug Administration (FDA). Izvo zvinoshandiswa pamwe chete nechikafu chakaderera mumafuta akazara uye cholesterol kudzikisa cholesterol. Kunyangwe Crestor naLipitor vese vari ma statin, iwo haana kufanana. Enderera kuverenga kuti udzidze zvakawanda nezve Crestor uye Lipitor.
Ndeupi mutsauko mukuru pakati peCrestor neLipitor?
Crestor (Chii chinonzi Crestor?) Uye Lipitor (Chii chinonzi Lipitor?) Mishonga inoderedza lipid. Ivo vanozivikanwa zvakare se statins, kana HMG-CoA reductase inhibitors. Mishonga yese iri miviri inowanikwa muchiratidzo uye generic fomu uye semapiritsi chete. AstraZeneca inogadzira iyo inonzi-zita rekuti Crestor, uye Pfizer inogadzira iyo zita-zita Lipitor. Crestor neLipitor zvinonyanya kushandiswa muvakuru; zvisinei, mune dzimwe nguva, dzinogona kushandiswa muvana.
| Misiyano mikuru pakati peCrestor neLipitor | ||
|---|---|---|
| Crestor | Lipitor | |
| Kirasi yemishonga | HMG-CoA reductase inhibitor (inozivikanwawo set statin kana lipid-inoderedza mumiririri) | HMG-CoA reductase inhibitor (inozivikanwawo set statin kana lipid-inoderedza mumiririri) |
| Brand / generic chinzvimbo | Brand uye generic | Brand uye generic |
| Chii chinonzi generic zita? | Rosuvastatin | Atorvastatin |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa | Hwendefa |
| Ndeipi muyero wakajairwa? | Muenzaniso: 10 mg zuva nezuva | Muenzaniso: 20 mg zuva nezuva |
| Inguva yakareba sei kurapwa kwacho? | Nguva refu | Nguva refu |
| Ndiani anowanzoshandisa mushonga? | Vakuru; vana makore manomwe zvichikwira (mune dzimwe nguva) | Vakuru; vana vane makore gumi zvichikwira (mune dzimwe nguva) |
Mamiriro ezvinhu akarapwa neCrestor uye Lipitor
Crestor uye Lipitor zvinoshandiswa kudzikisa cholesterol. Crestor kana Lipitor inofanirwa kushandiswa, pamwe chete nechikafu chakaderera mumafuta akazara uye cholesterol, apo chikafu chega chisina kushanda zvakakwana kudzikisa cholesterol. Crestor uye Lipitor yakaderera yakazara cholesterol, LDL, ApoB, uye triglycerides . Ivo zvakare vanowedzera HDL cholesterol, iyo yakanaka mhando cholesterol.
Zvimwe zvinongedzo zvakanyorwa mune chati iri pazasi. Crestor naLipitor havana kudzidza mukurapwa kwaFredrickson Type I uye V dyslipidemias.
| Mamiriro | Crestor | Lipitor |
| Hyperlipidemia uye yakavhenganiswa dyslipidemia muvakuru | Ehe | Ehe |
| Yemhuri Hypercholesterolemia muvana | Ehe | Ehe |
| Hypertriglyceridemia muvakuru | Ehe | Ehe |
| Primary dysbetalipoproteinemia (Type III hyperlipoproteinemia) muvakuru | Ehe | Ehe |
| Homozygous yemhuri hypercholesterolemia muvakuru | Ehe | Ehe |
| Inononoka atherosclerosis kufambira mberi muvakuru | Ehe | Ehe |
| Kudzivirira chirwere chemwoyo (chirwere chemwoyo, chirwere chemwoyo) | Ehe | Ehe |
Crestor kana Lipitor inoshanda zvakanyanya here?
Vatsvagidzi vakafananidza akati wandei ma statin mukiriniki yekuyedza inonzi iyo STELLAR kutongwa (Statin Therapies yeakakwidziridzwa Lipid Levels Inofananidzwa Pakati peDosi neRosuvastatin). Vakatarisa mhedzisiro yeLipitor, Crestor, Zocor, uye Pravachol pakudzikisa LDL (low-density lipoprotein) cholesterol mushure memavhiki matanhatu.
Chidzidzo ichi chakagumisa kuti Crestor yakadzikisa LDL cholesterol ne8.2% kupfuura Lipitor, uye Crestor yakadzora cholesterol yakazara zvakanyanya kupfuura mamwe ma statins ese akadzidziswa. Crestor yakawedzerawo HDL cholesterol (mhando yakanaka yecholesterol) kupfuura izvo Lipitor akaita. Mune varwere vakatora Crestor, zvinoenderana nedosi, 82-89% yakawana LDL cholesterol zvibodzwa, zvichienzaniswa ne69-85% yevarwere vakatora Lipitor. Ma statins ese aibvumidzwa zvakafanana.
Chimwe chidzidzo chakadaidza iyo SATURN kutongwa (Kudzidza kweCoronary Atheroma neIntravascular Ultrasound: Mhedzisiro yeRosuvastatin maringe neAtorvastatin) yakatarisa madosi epamusoro eCrestor-40 mg zuva nezuva uye Lipitor 80 mg zuva nezuva- uye nemhedzisiro yavo pakufambira mberi kwecoronary atherosclerosis. Coronary atherosclerosis ndiko kudzikira kwemitsipa yeropa uye kuwanda kwecalcium nemafuta anoiswa mumatsinga, zvichiita kuti zvive zvakaoma kuti ropa risvike pamwoyo, uye kuwedzera njodzi yehosha yemwoyo.
Chidzidzo chakatarisawo kuchengetedzeka pamwe nemhedzisiro. Mushure memakore maviri ehupamhi dosing, iro boka reCrestor raive nemazinga ezasi eLDL uye zvishoma zvishoma HDL mazinga kupfuura iro Lipitor boka. (Kunyangwe, zvingave zvakakosha kuti uzive kuti AstraZeneca, inogadzira Crestor, yakabhadharisa chidzidzo ichi. Zvakare, iyi mishonga yakapihwa pamiyero yepamusoro, izvo zvisina kujairika munzvimbo yekiriniki yemurwere wepakati.) Crestor naLipitor vakaita kudzoreredza kweatherosclerosis kusvika padanho rakafanana. Ose mairi madhiragi akange akaregererwa zvakanaka uye aive neakaderera zviitiko zvekusagadzikana kwebazi.
Mune kiriniki yekumisikidza, ese ari maviri madhiragi akajairwa zvakanyanya uye anoregererwa-zvakanaka. Mushonga unonyanya kushanda kwauri unogona kusarudzwa nemupi wako wezvehutano, uyo anogona kufunga nezvehutano hwako, nhoroondo, uye mishonga yaunotora iyo inogona kusangana neCrestor kana Lipitor.
Kuvhavha uye mutengo kuenzanisa kweCrestor vs. Lipitor
Crestor kana Lipitor yakafukidzwa neinishuwarenzi yakawanda uye zvirongwa zveMedare zvinorayirwa mumhando yavo yerosuvastatin kana atorvastatin. Kusarudza zita rezita-chigadzirwa kungangoita kuti ive yepamusoro copay kana inogona kunge isina kuvharwa.
Pamushonga chaiwo wemakumi matatu, 10 mg mahwendefa erosuvastatin (generic Crestor), mutengo wekunze-muhomwe ungangoita anenge $ 134. Iwe unogona kushandisa yemahara SingleCare coupon kudzikisa mutengo kusvika $ 11 kuma pharmacies anotora chikamu.
Chairo chinyoreso chemakumi matatu, makumi maviri emigiramu mapiritsi eatorvastatin (generic Lipitor) yaizotora madhora makumi masere nemaviri kana ukabhadhara muhomwe. Iyo SingleCare generic Lipitor coupon inogona kuunza mutengo pasi kusvika pamadhora gumi nemashanu.
Sezvo zvirongwa zvichisiyana uye zvichichinja, bata kambani yako yeinishuwarenzi kuti uwane ruzivo maererano neCrestor uye Lipitor's kufukidza.
| Crestor | Lipitor | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Hongu (zvakajairika) | Hongu (zvakajairika) |
| Inowanzo kufukidzwa neMedare Chikamu D? | Hongu (zvakajairika) | Hongu (zvakajairika) |
| Zvakawanda | Muenzaniso: 30, 10 mg mahwendefa | Muenzaniso: 30, 20 mg mahwendefa |
| Chaizvoizvo Medicare copay | $ 0- $ 20 | $ 0- $ 15 |
| SingleCare mutengo | $ 11 + | $ 15 + |
Wana kadhi reSpecialCare rekutora kadhi
Zvakajairika mhedzisiro mhedzisiro yeCrestor vs. Lipitor
Mhedzisiro inowanzoitika yeCrestor musoro, kurwadziwa kwemhasuru, kurwadziwa mudumbu, kuda kurutsa, uye kushaya simba.
Lipitor's yakajairika mhedzisiro mhedzisiro ndiyo yakajairwa kutonhora, kurwadza kwemajoini, manyoka, kurwadziwa mumagumo, uye urineti turakiti hutachiona.
Chinhu chisingawanzo asi chakakomba mhedzisiro yeCrestor uye Lipitor ndeye myopathy (kushomeka kwemhasuru) uye rhabdomyolysis (kuparara kwemhasuru yemhasuru, iyo inogona kukuvadza kwazvo). Ona chikamu cheyambiro kuti uwane rumwe ruzivo.
Iko kuitika kwemhedzisiro kunogona kusiyaniswa neyero. Iyi haisi rondedzero izere yemhedzisiro. Zvimwe, zvakakomba mhedzisiro mhedzisiro inogona kuitika. Taura nemupi wako wezvehutano nezve izvo mhedzisiro yaunotarisira kubva kuCrestor kana Lipitor, uye nemaitiro ekugadzirisa.
| Crestor | Lipitor | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kutemwa nemusoro | Ehe | 5.5% | Kwete | - |
| Nausea | Ehe | 3.4% | Ehe | 4% |
| Tsvina aches / kurwadziwa | Ehe | 2.8% | Ehe | 3.8% |
| Joint kurwadziwa | Ehe | Zvinosiyana | Ehe | 6.9% |
| Marwadzo mumativi | Kwete | - | Ehe | 6% |
| Urinary turakiti hutachiona | Kwete | - | Ehe | 5.7% |
| Kushaya simba | Ehe | 2.7% | Ehe | 6.9% |
| Kuzvidya mwoyo | Kwete | - | Ehe | 4.7% |
| Kuzvimbirwa | Ehe | 2.4% | Kwete | - |
| Manyoka | Kwete | - | Ehe | 6.8% |
| Marwadzo emudumbu | Ehe | ≥2% | Ehe | % haina kutaurwa |
| Kazhinji kutonhora | Kwete | - | Ehe | 8.3% |
Kwayaka: DailyMed ( Crestor ), Zuva Nezuva ( Lipitor )
Kubatana kwemishonga kweCrestor vs. Lipitor
Mhedzisiro yakakosha yekuziva nezve Lipitor ndeyekuti haufanire kunwa yakawandisa huwandu hwemuzambiringa wemazambiringa (anopfuura 1,2 litita pazuva). Yakawandisa mazambiringa mazambiringa anokwanisa kuwedzera Lipitor mazinga mumuviri wako, zvichikuita iwe mukana wekuti uwane myopathy (kushomeka kwemhasuru) uye rhabdomyolysis (mhasuru nyama kuputsika, iyo inogona kukuvadza zvakanyanya)
Aya matambudziko emhasuru anowanzoitika nekudyiwa kwepamusoro kwemuto wemazambiringa, asi zvinogona kuitika nemari shoma. Kana iwe ukadya grapefruit kana kunwa jisi remuzambiringa uye uchitora Lipitor, bvunza chiremba wako kuti yakadii yakachengeteka kushandisa, kana kana zviri nani kutora mumwe mushonga usingabatanidze ne grapefruit. Crestor haina kusangana kwemazambiringa muchero.
Crestor naLipitor vane kumwe kudyidzana kwezvinodhaka, semuenzaniso, ne cyclosporine, gemfibrozil, niacin, fenofibrate, colchicine, uye mimwe mishonga yekurwisa hutachiona inoshandiswa kuHIV. Kubatanidza Crestor kana Lipitor neimwe yemishonga iyi kunogona kuwedzera huwandu hwe statin, zvichikonzera njodzi yakanyanya ye myopathy uye rhabdomyolysis. Zvichienderana nekubatanidzwa kwemishonga uye nhoroondo yako yekurapa / mamiriro, chiremba wako angangoda kugadzirisa yako muyero wemushonga kana kusarudza mumwe mushonga.
Usati watora Crestor kana Lipitor, udza chiremba wako nezve yese mishonga yaunotora, kusanganisira tsamba, pamusoro-the-counter (OTC), uye mavitamini, kuti vagone kuona kana Crestor kana Lipitor yakachengeteka kwauri.
| Zvinodhaka | Kirasi yemishonga | Crestor | Lipitor |
| Cyclosporine | Immunosuppressant | Ehe | Ehe |
| Gemfibrozil | Mishonga yeiyo yakakwirira triglycerides | Ehe | Ehe |
| Mimwe antiviral mishonga yeHIV | Antiviral HIV mishonga | Ehe | Ehe |
| Itraconazole | Azole antifungal | Kwete | Ehe |
| Clarithromycin | Macrolide mishonga inorwisa mabhakitiriya | Kwete | Ehe |
| Darolutamide | Androgen receptor inhibitors yekenza yeprostate | Ehe | Kwete |
| Regorafenib | Kinase inhibitor yekenza | Ehe | Kwete |
| Warfarin | Anticoagulant | Ehe | Kwete |
| Niacin | Antilipemic mumiriri | Ehe | Ehe |
| Fenofibrate | Antilipemic mumiriri | Ehe | Ehe |
| Colchicine | Anti-kuravira mumiriri | Ehe | Ehe |
| Maalox Mylanta Rolaids | Antacids | Ehe | Kwete |
| Muchero wemazambiringa | Muchero wemazambiringa | Kwete | Ehe |
| Rifampin | Antimycobacterial | Kwete | Ehe |
| Mishonga yekudzivirira | Mishonga yekudzivirira | Kwete | Ehe |
| Digoxin | Cardiac glycosides | Kwete | Ehe |
Yambiro dzeCrestor uye Lipitor
- Muzviitiko zvisingawanzoitika, kushomeka kwemhasuru uye kuputsika kunogona kuitika nekuda kwemushonga wepasitini. Izvi zvinogona kuitika nechero chipimo chemushonga asi zvakajairika nedosi dzakakwirira. Shandisa nekuchenjerera kune varwere vane makore makumi matanhatu nemashanu kana kupfuura, varwere vane matambudziko eitsvo, uye varwere vane hypothyroidism iyo isiri pasi pekutonga. Njodzi idzi dzinowedzerawo kana mimwe mishonga ikatorwa pamwe chete neCrestor kana Lipitor, senge fenofibrate, niacin, cyclosporine, colchicine, kana imwe mishonga yemishonga inorwisa hutachiona inoshandiswa kuHIV. Kana iwe uine maronda asingatsanangurike emhasuru, kana kushaya simba kwemhasuru, kana hunyoro, kunyanya kana iwe uchinzwawo kuneta uye / kana uine fever, zivisa chiremba wako nekukasira. Crestor kana Lipitor inofanirwa kumiswa kana iwe wakanyanya kuwedzera creatine kinase mazinga kana kufungidzira myopathy.
- Mune zvisingawanzo zviitiko, mamiriro anonzi immune-mediated necrotizing myopathy (IMNM) anogona kuitika kubva kuchirapa. Zviratidzo uye zviratidzo zvinosanganisira mhasuru kushaya simba uye shanduko mumaragi.
- Varwere vanofanirwa kuve neropa enzyme lab miedzo vasati vatanga Crestor kana Lipitor, panguva yekurapa kana paine chero zviratidzo zvezvinetso zveropa, uye / kana kana chiremba paanonzwa kuti zvakakodzera kuongororwa kweropa uku. Statin mishonga inogona kuwedzera AST kana ALT mazinga. Muzviitiko zvisingawanzoitika, kutadza kwechiropa (kunouraya kana kusingauraye) kwakaitika kune varwere vanotora statins. Crestor kana Lipitor inofanirwa kumiswa nekukurumidza kana kukuvara kwechiropa kwakakomba kuchiitika. Kana iwe uine zviratidzo zvekuneta, kushaiwa kudya, weti yakasviba, kana yero yeganda kana maziso, bata chiremba wako ipapo ipapo.
- Shandisa Crestor kana Lipitor nekuchenjerera kune varwere vanonwa doro rakawanda.
- Shandisa Crestor kana Lipitor nekuchenjerera kune varwere vane nhoroondo yechiropa chirwere. Vanhu vane chirwere chiropa chinoshanda havafanirwe kushandisa Crestor kana Lipitor.
- Shanduko mumazinga eglucose uye hemoglobin A1C mazinga anogona kuitika kubva kuCrestor kana Lipitor. Iyo njodzi inowedzera pamwe nekushandisa pamwe kwe ketoconazole, spironolactone, kana cimetidine.
- Muzviitiko zvisingawanzoitika, kurasikirwa ndangariro kana kuvhiringidzika kunogona kuitika. Bata nyanzvi yako yehutano nekukurumidza kuti ubatsirwe kana iwe kana munhu waunoda akacherechedza chero shanduko.
- Usatore madosi maviri eCrestor kana Lipitor mukati maawa gumi nemaviri eumwe.
- Crestor kana Lipitor inogona kutorwa pamwe kana pasina chikafu chero nguva yezuva. Kumedza piritsi rakazara.
- Crestor kana Lipitor haifanire kushandiswa mukuzvitakura nekuda kwenjodzi yekukuvara kwechibereko. Usamwisa mwana paunenge uchitora Crestor kana Lipitor.
Kuwedzera Crestor yambiro:
- Varwere vanotora anticoagulant (senge warfarin) vanofanirwa kuongororwa zvakaringana vasati vatora Crestor, uye kazhinji pakutanga kwekurapwa kwesitina, kuona kuti INR inoramba yakatsiga.
- Varwere vanotora antacid ine aluminium uye magnesium vanofanirwa kutora iyo antacid kweinenge maawa maviri vatora Crestor.
Kuwedzera Lipitor yambiro:
- Kuwedzeredzwa kunwiwa kwe grapefruit uye / kana grapefruit muto (anopfuura 1.2 litita zuva nezuva) kusanganiswa neLipitor kunogona kuwedzera myopathy uye rhabdomyolysis njodzi.
Inowanzo bvunzwa mibvunzo nezve Crestor vs. Lipitor
Chii chinonzi Crestor?
Crestor is statin, kana HMG-CoA reductase inhibitor, inowanzo shandiswa kurapa yakakwira cholesterol. Zita rayo rinowanzoitwa rosuvastatin. Crestor inowanikwa mune zvese mhando uye generic fomu uye sehwendefa.
Chii chinonzi Lipitor?
Lipitor, senge Crestor, ndeye statin mishonga inoshandiswa kune yakakwira cholesterol. Iro zita rayo generic ndiyo atorvastatin. Inowanikwa mune fomu yepiritsi, mune zvese mhando uye generic.
Crestor neLipitor zvakafanana here?
Crestor uye Lipitor ese ari maviri ma statins. Ivo vanoshanda zvakafanana uye vane zvimwe zvakafanana. Nekudaro, ivo havana kunyatso kufanana. Iwe unogona kuverenga nezve mutsauko wavo mune ruzivo rwakataurwa pamusoro. Mamwe ma statins aungangodaro wakanzwa nawo anosanganisira Pravachol (pravastatin), Zocor (simvastatin), Livalo (pitavastatin), Lescol (fluvastatin), uye Mevacor (lovastatin).
Crestor kana Lipitor iri nani here?
Zvidzidzo zvinoratidza kuti madhiragi ese ari maviri anoshanda mukuderedza cholesterol (ona pamusoro chikamu). Zvimwe zvidzidzo zvinoratidza kuti Crestor inoshanda zvishoma; zvisinei, zvese zvinodhaka zvinoshanda uye zvinoregererwa zvakanaka. Kumbira mupi wako wezvehutano kana mumwe wemishonga iyi ungave wakakodzera iwe, zvichibva pane yako nhoroondo yekurapa.
Ndinogona here kushandisa Crestor kana Lipitor ndichiri nepamuviri?
Kwete Crestor kana Lipitor haifanire kutorwa nemukadzi ane nhumbu. Mishonga yese iri miviri yakapesana chaizvo kuti ishandiswe panguva yekuzvitakura. Vanogona kukonzera kukuvadza kune mwana asati aberekwa. Kana iwe uri kutora Crestor kana Lipitor uye woziva kuti iwe une nhumbu, rega kutora iyo statin uye bata chiremba wako nekukurumidza kune vekurapa kuraira.
Ndinogona here kushandisa Crestor kana Lipitor nedoro?
Kazhinji, zvakachengeteka kushandisa a diki kusvika pakati nepakati doro kana iwe ukatora Crestor kana Lipitor. Zvisinei, kana uine matambudziko echiropa, kana kunwa doro rakawandisa, bvunza nemupi wako wehutano usati wasanganisa statin nedoro. Vanhu vane chirwere chisingaperi chechiropa vanofanirwa kudzivirira doro zvachose pavanotora statin.
Crestor yakachengeteka kupfuura Lipitor here?
Crestor uye Lipitor vese vari vaviri vakashivirirwa zvakanaka. Chero chipi chinodhaka chine mhedzisiro, pamwe nezvimwe zvisingawanzo asi zvakakomba zvinogona kuve nemhedzisiro, futi. Zvidzidzo (ona pamusoro chikamu) zvakaratidza kuti mishonga yese yaibvumirwa mushe mumayedzo.
Ndezvipi zvekudya zvinofanirwa kudzivirirwa kana uchitora Crestor?
Paunotora Crestor (kana Lipitor), iwe unofanirwa kudya chikafu chine hutano chakaderera mumafuta akazara uye cholesterol.
Zvimwe zvekudya zvaungade kudzivirira ndezvakakora nyama, mukaka wakazara-mafuta, uye zviwitsi. Pane kudaro, tarisa pane zvekudya zvakaita semichero, miriwo, zviyo zvese, bhinzi, nzungu, uye mapuroteni akaonda sehuku nehove.
Kunyangwe Lipitor ichipindirana ne (yakawanda kwazvo) jisi remuzambiringa, Crestor yakachengeteka kutora nejusi remazambiringa.
Crestor inoita kuti uwedzere uremu here?
Crestor haina kubatana zvakanangana nekurema. Kana iwe uri kutora Crestor uye wobva waona shanduko yekurema, bata wako mupi wezvehutano.
