Mashandisiro anoita chirwere cheshuga Metformin kurapa PCOS

Zvinodhaka Info

Polycystic Ovary Syndrome (PCOS) iri hormonal kusagadzikana izvo zvinokanganisa zvakaomarara 5 mamirioni vakadzi muUnited States. Zviratidzo zvePCOS zvinosiyana munhu-nemunhu, izvo zvinogona kuita kuti zvive zvakaoma kuziva. Vakadzi vazhinji vanotambura chinyararire, vachirarama vasina kuziva kwemakore.

Masangano asiri-purofiti muUS ese anoshanda kuparadzira ruzivo nezve zviratidzo uye nzira dziripo dzekurapa - kubva pakuronga kubereka kusvika kune metformin. Asi inoramba iri imwe yeakanyanya kutsoropodza, asina kuchengetedzwa, asina kuongororwa uye ari pasi-mari mamiriro anokanganisa hutano hwevakadzi, anodaro Sasha Ottey, director director weiyo isiri purofiti PCOS Dambudziko Inc.

Sei vamwe vakadzi vachiwana PCOS, uye zvinovabata sei?

Dr. Felice Gersh , uyo anokunda mubairo-OB-GYN, anoti PCOS ndiyo yakajairika endocrine kusagadzikana kwevakadzi vane makore ekubereka-asi inosanganisira zvese zvikamu zvemuviri wemukadzi. Iyo inobata ese mashandiro emabasa pamwe neese maficha ekumwedzi uye kubereka. Zviratidzo zvakajairika inogona kusanganisira: hapana nguva, nguva isina kujairika, kana nguva inorema; kurwadziwa kwepamuviri; kuwedzera bvudzi kukura pachiso chako, inozivikanwa se hirsutism; acne; kurema kuwedzera kana matambudziko nekurasikirwa nehuremu hwemuviri uye zvigamba zveganda rakasviba gobvu.Maererano ne EndrocrineWeb , vakadzi vane PCOS vanogona kunge vane makumi maviri nemashanu kana anopfuura ma cysts pane ovary imwe chete.

Iko kune zvikonzero zvakasiyana siyana nei mukadzi ane zera rekubereka anogona kuvandudza PCOS, asi kutsvagurudza kunoratidza kuti genetics, insulin kushora, uye uyerogen yakawandisa (inozivikanwawo semahomoni echirume) zvese zvingangoita njodzi.

PCOS inobata vakadzi kubva kwakasiyana siyana mashure. Vakadzi vemarudzi ese uye madzinza vari panjodzi yeCPOS, anodaro Dr. Kate Killoran OB-GYN muMaine. Vakadzi vakafuta nevakadzi vane nhoroondo yemhuri vanowanzo kanganiswa.

Chii chinonzi kurapwa kwePCOS?

Kunyange pasina mushonga wePCOS, pane nzira dzekugadzirisa zviratidzo. Chirongwa chekurapa cheumwe neumwe murwere chichava chakati siyanei, zvichibva pane yavo chaiyo seti yezviratidzo.

Dr. Killoran vanoti kune mishoma mishonga inogona kupihwa varwere vePCOS, zvichienderana nekuti mamiriro acho anovabata sei. Ichi hachisi chinyorwa chakazara, asi chinosanganisira:

• Kudzora kubereka inogona kubatsira kudzora kukanganisika kwekuenda kumwedzi.
• Mishonga yekudzivirira izvo zvine estrogen inogona kubatsira kugadzirisa acne.
• Metformin kana imwe mishonga ye insulin senzwi inogona kubatsira nekukanganisa metabolic uye kunyange kugadzirisa kubereka.
• Letrozole inogona kukonzera ovulation apo vakadzi vane PCOS vari kuyedza kubata pamuviri.

Lifestyle modification, kunyanya kurovedza muviri uye macalorie-anorambidzwa dhayeti shanduko inogona kugadzirisa kana kudzosera PCOS, Dr. Killoran anowedzera.

Chii chinonzi metformin chinoitira PCOS?

Metformin mushonga unowanzo shandiswa kurapa zviratidzo zvePCOS. Iyo yakatanga kugadzirwa uye kazhinji inorayirwa kuti irape Type 2 Chirwere cheshuga, chirwere chemetabolism chakafanana nePCOS, anodaro Dr. Laurence Gerlis , chiremba mukuru muLondon, England.

Basa re metformin mumuviri kudzora shuga yeropa nekubatsira muviri kupindura zvirinani kune insulini inogadzira zvakasikwa, kudzikamisa huwandu hweshuga inogadzirwa nechiropa, uye kudzikira huwandu hweshuga ura hunowanwa kubva muchikafu, maererano neKudya. uye Drug Administration (FDA).

Dr. Gerlis vanoti metformin yePCOS, painotorwa nguva zhinji, inoderedza mwero wehuga yeropa nekuyera insulini uye kudzikisira zvimwe zvinokanganisa mamiriro ezvinhu.

Pane here mhedzisiro yekutora metformin yePCOS?

Kune mashoma kwazvo ezvekuchengetedza nyaya zvine chekuita nekugara uchishandisa metformin, kunze kwekusunungura matumbo, Dr. Gerlis anodaro. Gesi, manyoka, uye kurwadziwa mudumbu zvimwe zvinowanzoitika mhedzisiro yemetformin.

Dr. Gersh, kune rumwe rutivi, haataure metformin kuvarwere vake nekuti yakaverengerwa se endocrine kuvhiringidza nevamwe vesainzi vezvakatipoteredza. Kunyangwe paine kupokana kukuru kwakavakomberedza, endocrine anovhiringidza vakafungidzirwa kuti vanobatanidzwa neakachinja basa rekubereka, gomarara repazamu, zvisirizvo zvekukura mapatani, uye zvimwe.

Yakawanda sei metformin yandinofanira kutora yePCOS? Inguva yakareba sei metformin inofanira kutorwa kune PCOS?

Iko hakuna kubvumirana pane yakajairwa dosi kana nguva ye metformin yeCPOS; wepakati muyero uri 1,500 mg zuva nezuva. Vanachiremba kazhinji tanga varwere pa500 mg Mazuva ese, uye wedzera dosi zvishoma nezvishoma kudzora mhedzisiro yemetformin.

Metformin inowanikwa kuburikidza nemushonga chete, uye yakagamuchirwa neKudya neDrug Administration (FDA) mu 1994 muUnited States. Metformin inotorwa nemuromo, uye ndizvo inowanikwa pasi pemhandoFortamet, Glucophage , Joke , uye Riomet.

Sezvo metformin yakanyatsogadzwa ine yakanaka chengetedzo profiles, zvinokurudzirwa kwazvo kuti utange pakutanga kwekutungamira kwePCOS, Dr. Gerlis vanopa zano.

Metformin inobatsira sei PCOS uye kurasikirwa uremu? Metformin inobatsira sei kushaya mbereko?

Yekureruka kurasikirwa uye kushaya mbereko, kushanda kwemetformin hakusi sekucheka kwakajeka.

Dr. Killoran anoti varwere vane PCOS vangangoda kuyedza metformin kurapa kugadzirisa zviratidzo zvavo vanowanzo nyanyisa kana kufutisa uye vachiedza kubata pamuviri, kana vari kuedza kudzivirira metabolic syndrome, chirwere chemoyo, kana kuwedzera chirwere cheshuga mellitus.

Nepo kushandiswa kwemetformin kuchisanganiswa nekudzikira uremu, mhedzisiro yacho haienderane, anodaro.

Pane here zvimwe zvakasarudzika nzira kune metformin yePCOS?

Dr. Gersh vanotenda kuti iyo nzira yekutanga nzira yekugadzirisa PCOS ndeyekuchinja mararamiro uye maitiro matsva, senge kudya chikafu chinodyarwa nemiti, kudzikisira kushushikana, kutarisa kurara, uye kubatanidza kurovedza muviri. Mishonga inowanzokurudzirwa kurapwa kwePCOS iri kutsvaga nzira dzekushanda zvakanyanya uye kudya zvakanyanya chikafu chizere.

Kune varwere vake, Dr. Gersh anokurudzira akasiyana mavitamini ekuwedzera, pamwe chete neshanduko yekudya uye kurovedza muviri kurapa zviratidzo zvePCOS. Semuenzaniso, vhitamini B12 inogona kukurudzirwa kutorwa pamwe kana mushure mekurapa metformin, sezvo malabsorption yevhitamini B12 inogona kuve mhedzisiro yemetformin kana ikashandiswa kwenguva refu.

Zvichakadaro, Dr. Killoran anoti PCOS inobata munhu wega zvakasiyana. Anoti zvakakosha kurapa PCOS kunyangwe zviratidzo zvevarwere zvisina kunetsa, zvakadaro. Vese vanofanirwa kuziva nezve njodzi yavo yezvekupedzisira matambudziko ezvehutano senge metabolic syndrome uye chirwere chemoyo, anopa zano. Sarudzo yekurapa PCOS uye nezvinofanirwa kuve zvinoenderana nezviri zviratidzo zvemukadzi asi zvakare kudzikisa njodzi.

Kana iwe uri kufunga nezve metformin, ronga kuteedzera nachiremba wako kuti uone zvakakunakira iwe.