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Propranolol mhedzisiro uye kudyidzana, uye maitiro ekuzvidzivirira

Zvinodhaka Info

Propranolol (generic Inderal) mushonga unorapwa unobata zviratidzo zveBP, zvakadai sekurwadziwa pachipfuva. Usati watora mushonga uyu, varwere vanofanira kuziva nezvepropranolol mhedzisiro, yambiro, uye kudyidzana. Dzidza maitiro ekudzivirira aya mhedzisiro pazasi.

Chii chinonzi propranolol?

Propranolol imhando generic mishonga inotengeswa sezita-zita Inderal LA , Inderal XL, InnoPran XL, uye Hemangeol. Izvo ndezve beta-adrenergic blocking vamiririri (kana beta-blockers ) kirasi yemishonga, iyo inobatsira kurova kwemoyo nyore uye nesimba shoma. Propranolol inongowanikwa chete nemushonga. Heano mamwe ehutano mamiriro ayo Chikafu neDrug Administration (FDA) yakatendera propranolol kurapa:

Arrhythmia: Kurova kwemoyo zvisina kujairika uko kunonoka kana kukurumidza.
Angina: Kurwadziwa pachifuva kunoitika kana ropa risina kunyatsoyerera richienda pamoyo.
Kudengenyeka: Kufambisa uye kuita zvine mutsindo kwemaoko, kumeso, tambo dzenzwi, kana musoro.
Hypertension: Kuwedzera kweropa nekuda kwesimba reropa pamadziro etsinga arikanyanya. Kuwedzera kweropa mazinga chero chinhu chiri pamusoro pe140 / 90. Propranolol-HCTZ , mushonga unobatanidza propranolol ine diuretic, inobata hypertension.
Kurwisa kwemoyo: Kurwadziwa kwemoyo (myocardial infarction) kunoitika kana kuyerera kweropa kuenda pamoyo kwakavharwa. Propranolol inogona kubatsira kudzivirira uye kubata chirwere chemwoyo.
Migraine misoro: Migraines yakanyanya kutemwa nemusoro iyo propranolol inogona kubatsira kudzivirira. Vatsvagiri vanofunga kuti propranolol yakanaka kune migraines nekuti inovhara iyo hormone adrenaline kubva mukukonzeresa kusagadzikana mumuviri.
Infantile hemangioma: Chirwere chetsinga cheropa chinogona kukanganisa vacheche kusvika pamwedzi mishanu.

Propranolol inogona kubata mamwe mamiriro, senge kushushikana uye kutya kwekutyisa , pane imwe nyaya nenyaya. Vatsvakurudzi vari kutsvaga kuti propranolol inogona sei kubata mamwe marudzi e gomarara . Dosero repropranolol rinosiyana zvichienderana nemamiriro acho uye rinogona kubva pa10 mg kusvika 160 mg.

RELATED: Chii chinonzi Inderal LA? | Chii chinonzi Propranolol?

Zvakajairika mhedzisiro mhedzisiro yepropranolol

Sezvakaita chero mishonga, panogara paine mukana wemhedzisiro. Heano mamwe akajairika mhedzisiro mhedzisiro yepropranolol:

Dzungu
Musoro wakareruka
Kuneta
Yakadzikira bonde drive
Nausea
Dumbu kurwadziwa
Manyoka
Kuzvimbirwa

Yakakomba mhedzisiro mhedzisiro yepropranolol

Kutora propranolol kunogona kukonzera zvakakomba mhedzisiro. Heano mamwe eakakomba uye anogona kunge akareba-nguva mhedzisiro mhedzisiro yekuziva kana uchifunga kana kutora propranolol:

Hallucinations
Maoko anotonhora kana tsoka
Tsvina kushaya simba
Tsandanyama tsandanyama
Kufema kwekufema
Kurasikirwa kwendangariro
Kuchengetwa kwemvura
Ropa shuga inoshanduka
Kusarara uye kurota zvinotyisa
Allergic reaction
Kusvipa
Kuzununguka
Kurera huremu
Mapundu eganda

Vamwe vanhu vanonzwa kunetsekana kuti hunhu hwavo huchashanduka kubva pakutora propranolol, uye kunyangwe zvisingawanzo, izvi zvinogona kuitika. Propranolol inogona kukonzera kushanduka kwemanzwiro uye kushushikana. Inogona zvakare kukonzera matambudziko ekurangarira nekuda kwenzira yainoita norepinephrine uye epinephrine, ayo akasungirirwa mukushanda kwendangariro. Chero shanduko yemanzwiro inofanirwa kutaurwa kuna chiremba nekukurumidza sezvazvinogona.

Zvimwe zvinokanganisa zvepropranolol zvinoda kurapwa nekukurumidza zvinosanganisira kunetseka kufema, kufema, kuzvimba kwemaoko kana kumeso, uye kuputika kweganda. Zviratidzo izvi zvinoratidza kusagadzikana, izvo zvinogona kutyisidzira hupenyu.

Iwe unofanirwa kumira kutora propranolol kana zvakakomba mhedzisiro ikaitika, asi chete pasi pekutungamira kwechiremba, sekuenderana nedosi uye mhedzisiro, chiremba wako angangoda kuti iwe ubvise zvishoma propranolol, anodaro Reuben Elovitz, MD, muvambi uye CEO we Yakavanzika Hutano Dallas . Pane zvinokonzeresa nekumira nekukasira mishonga zvichienderana nechikonzero chawakatangwa pamushonga.

Kunyangwe kutora propranolol kunogona kukonzera mhedzisiro, ichiri mushonga unogona kuita zvakawanda zvakanaka. Inobatsira moyo kushanda, haizokuvadze moyo, uye ine maitiro akanaka pane immune system nekuwedzera huwandu hweT masero mumuviri. Pachagara paine zvayakanakira nezvayakaipira kumushonga wega wega, uye kune vanhu vazhinji, bhenefiti yepropranolol inopfuura zvakanyanya kuderera.

Anotora nguva yakareba sei propranolol mhedzisiro?

Mhedzisiro mhedzisiro yepropranolol inogona kugara chero kubva mazuva kusvika mavhiki. Mazhinji mhedzisiro anozoenda mukati memazuva mashoma muviri uchichinjira kumushonga. Kune vamwe, ino nguva yekugadzirisa inogona kutora nguva yakareba. Mhedzisiro inogona kuwedzera kana kuve nani sezvo madosi achiwedzera kana kuderera. Yenguva refu-mhedzisiro mhedzisiro yepropranolol inogoneka, asi izvi hazviitike kune wese munhu.

Propranolol yambiro

Propranolol haisi yemunhu wese. Dr. Elovitz vanotsanangura kuti vanhu vane zvinotevera zvehutano havafanirwe kutora propranolol:

Bradycardia (isina kujairika inononoka kurova kwemoyo)
Chirwere (kunetseka kufema kubva kune yakadzvanywa nemhepo)
Kudzora moyo kusadzora (moyo usinga pombi mushe)
Peripheral vascular chirwere (yakavharirwa kana kupaza mitsipa yeropa)
Chirwere cheshuga (chirwere cheshuga yakakwira muropa)
Pheochromocytoma (bundu readrenal gland tishu)
Myasthenia gravis (isina kusimba tsandanyama chirwere)
Hypotension (yakaderera BP)
Orthostatic hypotension (yakaderera BP iyo inoitika kana wakamira kubva wakagara kana wakarara pasi)

Vanhu vanorarama ne hyperthyroidism (yakanyanyisa utachiona), chirwere chaRaynaud, chirwere chechiropa, chirwere cheitsvo, chirwere chemapapu, kana chirwere chemwoyo, vanofanirwa kutaura nemubatsiri wavo wehutano vasati vatora propranolol. Kuva neaya mamiriro ekurapa kunogona kukonzera kusagadzikana kuita propranolol, zvichitungamira kune mamwe matambudziko ehutano.

Propranolol panguva yekuzvitakura

Propranolol inogona kunge isina kuchengetedzeka kune vakadzi vane nhumbu kutora. Iko hakuna kuve nezvakakwana zvidzidzo zvakaitwa kuratidza kuti propranolol inobata sei fetus, asi ongororo inoratidza kuti mushonga unogona kupfuura kubva kuna amai kuenda kune vacheche kuburikidza nemukaka wemukaka. Vakadzi vane nhumbu kana avo vanogona kuve nepamuviri vanofanirwa kubvunza kune avo vezvehutano vasati vatora kana nekukurumidza kurega propranolol.

Kurambidzwa kwezera

Propranolol dzimwe nguva inoshandiswa kurapa mamiriro ekurapa senge infantile hemangioma kune vamwe vana, asi izvi hazvireve kuti ndiwo mushonga wakakodzera wemwana wese. Chiremba anongopa propranolol kumwana kana zvichidikanwa.

Propranolol inorayirwa kune vakuru vakuru nekuchenjerera, kunyanya kune avo vane chiropa, itsvo, uye nemoyo mamiriro. Vamwe zvidzidzo inoratidza kuti vakuru vakura kupfuura makumi matanhatu vane hypertension havafanirwe kutora propranolol, asi vamwe varwere vane kutadza kwemoyo vanogona kuida Vanachiremba vanogara vachipa propranolol pane kesi-ne-kesi hwaro.

Kushandiswa kwenguva refu kweprranolol

Se beta-blocker, kushandiswa kwenguva refu kweprranolol kunogona kudzivirira kurwisa kwemoyo uye kuchengetedza hutano hweropa. Hazvishamise kuti mumwe munhu atore beta-blockers kwemakore akati wandei, kunyanya zvichitevera chirwere chemwoyo, asi vanachiremba vatanga kudaro mubvunzo kunyangwe kushandiswa kwenguva refu kuchidikanwa.

Kushandiswa kwenguva refu kwe beta-blockers kunogona kukonzera zvakajairika mhedzisiro ku kuwedzera . Inogona zvakare kuvhara zviratidzo zveshuga muropa mune vanhu vane chirwere cheshuga, icho chinogona kuve chinogona kutyisidzira hupenyu. Yakakwira dosi yepropranolol iyo inotorwa-yakareba inogona kutokonzeresa matambudziko emoyo uye kukonzera zvisina kujairika moyo moyo.

Propranolol haisi mushonga uyo mumwe munhu anogona kubva arega kutora, kunyangwe akave nemhedzisiro. Kungoerekana kumisa propranolol kunogona kukonzera kurwadza kwemoyo uye kurwadziwa kwepfupa kwakanyanya. Kubvunza chiremba ndiyo nzira yakanakisa yekuchengetedza izvi kuti zviitike.

Propranolol kudyidzana

Kungofanana nepropranolol haina kuitirwa kutorwa nemunhu wese, zvakare haifanire kutorwa nemimwe mishonga. Kutora propranolol nemishonga iyi kunogona kukonzera kusangana kwakashata:

Alpha anovharira: Prazosin
Anticholinergics: Scopolamine
Mimwe yakakwira BP. Clonidine , acebutolol , nebivolol, digoxin , metoprolol
Mimwe mishonga yemwoyo: Quinidine , digoxin , verapamil
Steroid mishonga: Prednisone
Nonsteroidal anti-anogumbura zvinodhaka (NSAIDs): Aspirin , ibuprofen
Zvimwe zvinodzvinyirira. Fluoxetine , fluvoxamine

Iyi rondedzero yemishonga haina kukwana. Vashandi vehutano vanogona kupa rondedzero izere yekudyidzana kwemishonga. Mazhinji mavitamini uye ekuwedzera akachengeteka kutora nepropranolol, asi mamwe akaita saSt. John's Wort anogona kunge asiri.

Kunze kwemishonga, propranolol haifanire kutorwa nedoro. Doro rinogona kuwedzera mwero weropa wepropranolol, ichikonzera kuti ive isina kuchengetedzeka. Kunwa zvakanyanya caffeine kunofanirawo kudzivirirwa nekuti caffeine inogona kuwedzera kushushikana uye kuwanda kweropa.

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Propranolol vs. propranolol ER mhedzisiro

Propranolol inouya nenzira mbiri dzakasiyana dzinoshanda zvishoma zvishoma zvakasiyana. Kugara waburitsa propranolol inofanirwa kutorwa kakawanda pazuva kuti ive nechokwadi chekuti inoshanda. Propranolol yakawedzerwa-kuburitswa (ER) inongoda kutorwa kamwe chete pazuva nekuti inononoka kuburitsa propranolol hydrochloride mumuviri.

Propranolol ER inowanikwa kutenga se60 mg, 80 mg, 120 mg, uye 160 mg capsules. Iyo muyero muyero yepropranolol ER ndeye 80 mg inotorwa kamwe pazuva, izvo zvakakwirira kupfuura muyero wekuburitsa propranolol nekukurumidza nekuti inongotorwa kamwe chete.

Vamwe vanhu vanofarira vhezheni-yakaburitswa vhezheni nekuti ivo vanongofanirwa kunetseka nezvekutora kwavo mishonga kamwe pazuva. Nekudaro, chiremba anozogona kuona kuti ndeipi vhezheni yakanakira mumwe munhu zvichibva pane zvavanoda uye zviratidzo.

Actavis Elizabeth anogadzira iyo generic vhezheni yepropranolol yakawedzerwa-kuburitswa. Iko zita repropranolol HCl ER ndiHemangeol. Shanduro dzemhando dzose dzemishonga dzinowanzo dhura pane shanduro dzemazita, asi dzinoshanda zvakafanana uye dzinoshanda zvakaenzana.

Iyo mhedzisiro mhedzisiro yeyakajairwa propranolol uye propranolol yakawedzerwa-kuburitswa ingangofanana. Iyo yambiro, chenjedzo, uye kudyidzana kwezvinodhaka zvepropranolol zvakare zvinomirira propranolol ER.

Maitiro ekudzivirira propranolol mhedzisiro

Nzira yakanakisa yekudzivirira propranolol mhedzisiro ndeyekutevera mirairo yekugadzira uye chero mirawo yakapihwa nachiremba.

Propranolol doses inoenderana nezera remurwere, zviratidzo zvega, uye nhoroondo yekurapa, asi iyo muyero muyero 40 mg inotorwa kaviri pazuva. Mapiritsi eprolololol anogara achingoburwa anofanirwa kutorwa padumbu risina chinhu kuti uve nechokwadi chekupinza mumuviri. Mahwendefa ePropranolol akawedzerwa-kuburitswa (ER) anogona kutorwa pamwe kana pasina chikafu, asi anofanirwa kugara achitorwa zvakaringana, kungave nekudya kana pasina chikafu, kuti uone kuti mwero isingachinjiki inodhonzwa nemuviri. Zvakare, kutora propranolol ER nechikafu kunogona kubatsira kudzivirira kushungurudzika mudumbu uye kuyeuka KUSA kutsenga kana kupwanya aya mapiritsi eEER kana iro rose danho rinogona kutorwa nekukurumidza. Propranolol inowanzo kutorwa kamwe mangwanani uye zvakare nguva yekurara isati yasvika, asi izvi zvinogona kuchinja zvichibva pane zvinokurudzirwa nemupi wezvehutano.

Mushonga wekushaya wepropranolol unogona zvakare kukonzera mhedzisiro. Kutora dhosi rakarasika munguva pfupi mushure mekurangarira zvinobatsira kudzivirira mhedzisiro kubva mukuitika kana kuwedzera. Nekudaro, kana ingangove nguva yekutora inotevera dosi, saka murwere haafanire kutora imwe yekuwedzera dosi kuti awane iyo yakashaikwa huwandu.

Propranolol inofanirwa kuchengetwa pane tembiricha yemukati kure nekupisa, zuva rakananga, uye tembiricha inotonhora. Izvi zvinhu zvakatipoteredza zvinogona kuchinja mishonga uye nemashandiro ayo. Chengetedza zvinodhaka kunze kwekusvika kwevana. Tsvaga zano rekurapa nekukasira kana mwana akanganisa kutora propranolol.

Kana iyo mhedzisiro mhedzisiro yepropranolol yakanyanyisa, vanachiremba vanogona kupa mushonga wakasiyana. Kungoti nekuti mumwe munhu anotanga kutora beta-blocker sepropranolol, hazvireve kuti vachatofanira kuitora zvachose. Mishonga senge ACE inhibitors uye maARB anobata mamwe mamiriro akafanana anoita beta-blockers, uye anogona kushanda zvirinani kune vamwe vanhu. Heano mamwe eanonyanya kutaurwa ACE inhibitors nemaARBs: