Protonix vs. Nexium: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Protonix (pantoprazole) uye Nexium (esomeprazole) mishonga miviri inoshandiswa kurapa matambudziko egwara rekudya, senge gastroesophageal Reflux chirwere (GERD). GERD chirwere chisingaperi chinokura apo dumbu acid rinowanzoyerera richidzokera mudumbu kubva mudumbu. Izvi zvinogona kutungamira kuzviratidzo sekushungurudzika uye kuomarara zvakanyanya senge esophagitis.
Ose Protonix neNexium chikamu cheboka remishonga rinonzi proton pump inhibitors (PPIs). Ivo vanoshanda nekuvharira mapurotoni mapampu mudumbu, ayo anoitisa kugadzirwa kweacid. Mukuita, Protonix neNexium vanobatsira kudzora kugadzirwa kweasidhi mudumbu.
Ndeupi mutsauko mukuru pakati peProtonix neNexium?
Protonix, iyo inogadzirwa naPfizer, ndiro zita rekuti pantoprazole. Iyo mishonga yekunyorera iyo inoshandiswa kurapa erosive esophagitis muvakuru uye vana vane makore mashanu makore nekure. Inowanikwa se 20 mg uye 40 mg inononoka-kuburitsa piritsi, pamwe ne40 mg yemvura kuturika. Mune zvimwe zviitiko, Protonix inogona kupihwa seinopinda (IV) jekiseni.
Nexium inogadzirwa neAstraZeneca uye ndiro zita rezita re esomeprazole. Inowanikwa seyakanyorwa kana kupfuura-the-counter (OTC) mushonga unoshandiswa kurapa GERD muvakuru, vana, uye vacheche vane makore 1 mwedzi zvichikwira. Kusiyana neProtonix, Nexium inouya se20 mg uye 40 mg inononoka-kuburitsa capsule. Nexium inowanikwawo se 2.5 mg, 5 mg, 10 mg, 20 mg, uye 40 mg kusimiswa kwemvura.
| Misiyano mikuru pakati peProtonix neNexium | ||
|---|---|---|
| Protonix | Nexium | |
| Kirasi yemishonga | Proton pump pump inhibitor (PPI) | Proton pump pump inhibitor (PPI) |
| Brand / generic chinzvimbo | Brand uye generic vhezheni iripo | Brand uye generic vhezheni iripo |
| Chii chinonzi generic zita? | Pantoprazole | Esomeprazole |
| Ndeapi mafomu (s) ayo mushonga unouya? | Kunonoka-kuburitsa piritsi Granules packet yekumiswa kwemvura Inopinza poda yejekiseni | Kunonoka-kuburitsa kapsule Granules packet yekumiswa kwemvura Inopinza poda yejekiseni |
| Ndeipi muyero wakajairwa? | 40 mg kamwe pazuva | 20 kana 40 mg kamwe pazuva |
| Inguva yakareba sei kurapwa kwacho? | Kusvikira kumavhiki masere | 4 kusvika kumavhiki masere zvinoenderana nemamiriro ari kurapwa |
| Ndiani anowanzoshandisa mushonga? | Vakuru nevana vane makore mashanu zvichikwira | Vakuru, vana, uye vacheche vane makore 1 mwedzi zvichikwira |
Mamiriro ezvinhu anorapwa neProtonix neNexium
Protonix neNexium vanogona kurapa GERD nemamiriro akasanganiswa neGERD, senge acid Reflux (chirungurira). Ose ari maviri mishonga zvakare FDA inogamuchirwa kurapa erosive esophagitis, kana kuzvimba kwetambo yegurokuro.
Nexium zvakare FDA inogamuchirwa kurapa hutachiona hweHelicobacter pylori (H. pylori). Rudzi urwu rwehutachiona runokura apo H. pylori mabhakitiriya anokanganisa nzira yekugaya, izvo zvinogona kutungamira kune maronda. Mukuwedzera kune maronda anokonzerwa naH. Pylori, Nexium inogona kudzivirira njodzi yemaronda anosangana neasina-steroidal anti-anogumbura zvinodhaka (NSAIDs).
Zvese Protonix neNexium zvinogona kushandiswa kurapa hypersecretory mamiriro, senge Zollinger-Ellison syndrome. Aya mamiriro anozivikanwa nekuwedzeredza kugadzirwa kwemudumbu asidhi. Protonix neNexium inogona zvakare kushandiswa kurapa peptic ulcers, iyo inosanganisira zvese duodenal uye mudumbu maronda.
Protonix neNexium zvinokurudzirwa chete kuti zvishandiswe kwenguva pfupi, kana kusvika kumavhiki masere kazhinji.
| Mamiriro | Protonix | Nexium |
| Gastroesophageal Reflux chirwere (GERD) | Ehe | Ehe |
| Erosive esophagitis | Ehe | Ehe |
| Hypersecretory mamiriro | Ehe | Ehe |
| H. pylori hutachiona | Kunze-chitaridzi | Ehe |
| Njodzi yekudzora yeNSAID-inosanganisirwa maronda emudumbu | Kunze-chitaridzi | Ehe |
| Maronda ehudyu | Kunze-chitaridzi | Kunze-chitaridzi |
| Zvironda zvemudumbu | Kunze-chitaridzi | Kunze-chitaridzi |
| Kushungurudza | Kunze-chitaridzi | Ehe |
Protonix kana Nexium inoshanda zvakanyanya here?
Kliniki miedzo yakaratidza kuti pantoprazole uye esomeprazole zvakafanana zvinoshanda. Imwe kiriniki kuyedzwa achifananidza kubudirira ye40 mg ye pantoprazole kusvika 40 mg esomeprazole mune varwere vane GERD. Vanenge varwere mazana mashanu nemakumi masere vaisarudzika kuti vagamuchire kana pantoprazole kana esomeprazole pamusoro pe4, 8, kana masvondo gumi nemaviri ekurapwa. Kukwana kuregererwa kweGERD kwakawanikwa pamwe neese PPI pamitengo yakafanana.
Mune yakasarudzika, yakapofumara-bofu kiriniki kuyedzwa, kushanda kwepantoprazole uye esomeprazole kwakafananidzwa nekurapa GERD. Vanenge mazana maviri evarwere vakasarudzika kuti vagamuchire kana 40 mg yepantoprazole zuva nezuva kana 40 mg esomeprazole zuva nezuva. Ose maPPI akawanikwa ari zvakafanana zvinobudirira pamwe nekuchengetedzeka kwakaenzana uye kushivirira.
Bvunza mupi wezvehutano nezve yakanakisa yekurapa sarudzo yako. Wako wekutanga wekuchengeta anogona kukuendesa kuna chiremba uyo anonyanya kugadzirisa gastroenterology kuti uwane mamwe mazano ekurapa.
Kuvhavha uye mutengo kuenzanisa kweProtonix vs. Nexium
Mazhinji Medicare uye zvirongwa zveinishuwarenzi zvinovhara iyo generic vhezheni yeProtonix, pantoprazole. Medicare copays inogona kubva pamadhora 0 kusvika $ 17 epantoprazole. Pasina inishuwarenzi, avhareji yemari mutengo weProtonix iri $ 522. Nekudaro, neProtonix coupon kubva kuSingleCare, iyo generic mutengo unosvika madhora gumi nerimwe.
Mimwe Medicare uye zvirongwa zveinishuwarenzi zvinogona kuvhara Nexium kana yayo generic vhezheni, esomeprazole. Medicare copays ye esomeprazole inogona kubva pa $ 1 kusvika $ 41. Ivhareji mutengo wekutengesa weNexium iri $ 478 zvinoenderana nehuwandu uye simba rakatemwa. Uine SingleCare Nexium coupon, avhareji mutengo unogona kudzikiswa kusvika angangoita $ 27.
| Protonix | Nexium | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe, seyakajairika vhezheni | Ehe, seyakajairika vhezheni |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe, seyakajairika vhezheni | Ehe, seyakajairika vhezheni |
| Zvakawanda | Mahwendefa makumi matatu (40 mg) | Mahwendefa makumi matatu (40 mg) |
| Chaizvoizvo Medicare copay | $ 0– $ 17 | $ 1– $ 41 |
| SingleCare mutengo | $ 11 + | $ 27 + |
Zvakajairika mhedzisiro mhedzisiro yeProtonix vs. Nexium
Mhedzisiro inowanzoitika yeProtonix ndeyekutemwa nemusoro, manyoka, kuda kurutsa, kurwadziwa mudumbu, kurutsa, gasi, dzungu, uye kurwadziwa kwemajoini.
Zvinowanzoitika mhedzisiro yeNexium zvinosanganisira kurwadziwa nemusoro, manyoka, kuda kurutsa, gasi, kurwadziwa mudumbu, kuzvimbirwa, uye kuoma muromo.
Yakakomba mhedzisiro mhedzisiro yePPIs inowanzo kuve yakabatana nekureba-kwenguva refu kushandiswa. Zvimwe zvakakomba mhedzisiro zvinogona kusanganisira osteoporosis-inoenderana nekuputsika kwemapfupa, vhitamini B12 kushomeka, uye yakaderera magnesium mazinga (hypomagnesemia).
| Protonix | Nexium | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kutemwa nemusoro | Ehe | 12% | Ehe | ≥1% |
| Manyoka | Ehe | 9% | Ehe | ≥1% |
| Kuzvimbirwa | Ehe | <2% | Ehe | ≥1% |
| Muromo wakaoma | Ehe | <2% | Ehe | ≥1% |
| Nausea | Ehe | 7% | Ehe | ≥1% |
| Dumbu kurwadziwa | Ehe | 6% | Ehe | ≥1% |
| Kusvipa | Ehe | 4% | Ehe | <1% |
| Dzungu | Ehe | 3% | Ehe | <1% |
| Gasi | Ehe | 4% | Ehe | ≥1% |
| Joint kurwadziwa | Ehe | 3% | Kwete | - |
Kakawanda hakubvi pane data kubva kumusoro-kuenda-kumusoro kutongwa. Izvi zvinogona kunge zvisiri rondedzero izere yemhedzisiro mhedzisiro inogona kuitika. Ndokumbira utarise kuna chiremba wako kana mupi wezvehutano kuti udzidze zvimwe.
Kwayaka: DailyMed ( Protonix ), Zuva Nezuva ( Nexium )
Kubatana kwezvinodhaka zveProtonix vs. Nexium
Protonix neNexium, semamwe maPPI, vanobatana nemazhinji emimwe mishonga. Aya maPPI anofanirwa kuongororwa kana kudzivirirwa nemamwe madhiragi anoenderana nedumbu acidity yekumwa. Zvinodhaka zvinoenderana nedumbu acidity yekumwa zvinosanganisira simbi munyu, erlotinib, ketoconazole, uye mycophenolate mofetil.
Protonix neNexium vanogona zvakare kudyidzana nemishonga yemaARV, kana mishonga inowanzo shandiswa kurapa HIV. PPIs dzinogona kuwedzera kana kudzikisa huwandu hweropa hwemishonga yema antiretroviral, izvo zvinogona kukonzeresa kune njodzi yekuwedzera huturu kana kudzikisira kushanda nemishonga yemaARV.
Iko kushandiswa kweProtonix kana Nexium ine warfarin kunogona kuwedzera njodzi yekubuda ropa.
Nexium inofanira kuongororwa kana kudzivirirwa ne diazepam nekuti inogona kuwedzera huwandu hweropa re diazepam uye inotungamira kune yakanyanya njodzi yemhedzisiro. Iko kushandiswa kweNexium uye clopidogrel pamwechete kunofanira kudzivirirwa. Nexium inogona kudzikisira mashandiro anoita clopidogrel mumuviri, izvo zvinogona kuwedzera njodzi yekugwamba kweropa.
| Zvinodhaka | Rudzi rwezvinodhaka | Protonix | Nexium |
| Atazanavir Rilpivirine Nelfinavir Saquinavir | Antiretrovirals | Ehe | Ehe |
| Ketoconazole | Antifungal | Ehe | Ehe |
| Ferrous sulfate Ferrous gluconate Ferrous fumarate | Iron munyu | Ehe | Ehe |
| Mycophenolate mofetil Methotrexate | Immunosuppressant | Ehe | Ehe |
| Erlotinib | Chemotherapy | Ehe | Ehe |
| Digoxin | Cardiac glycoside | Ehe | Ehe |
| Warfarin | Anticoagulant | Ehe | Ehe |
| Diazepam | Benzodiazepine | Kwete | Ehe |
| Clopidogrel | Antiplatelet | Kwete | Ehe |
Bvunza nyanzvi yezvehutano kune kumwe kudyidzana kwezvinodhaka
Yambiro dzeProtonix neNexium
Iko kushandiswa kwenguva refu kwePPIs kunogona kutungamira kune yakawedzera njodzi yekutyoka kwemapfupa, kunyanya kune vanhu vakatowanikwa vaine osteoporosis. Bone mineral density inogona kuda kuongororwa mukati menguva refu kurapwa nePPIs.
Vamwe varwere vakaona acute tubulointerstitial nephritis (TIN) vachitora Protonix kana Nexium. Nephritis ndiko kuzvimba kweitsvo, izvo zvinogona kutungamira mukudzikira kweitsvo.
Iko kushandiswa kwePPIs kunogona kuve kwakabatana neyakawedzera njodzi yeClostridium difficile-inosanganisirwa manyoka. Avo vanosangana nemanyoka anoramba aripo vangangoda kuongororwa, kunyanya muchipatara.
Kutora Protonix kana Nexium kunogona kuwedzera njodzi yekudzikira kweropa re magnesium (hypomagnesemia) kana vhitamini B12 (kushomeka kwevhitamini B12). Pane njodzi yakawedzera ye hypomagnesemia uye kushomeka kwevhitamini B12 kune avo vari kurapwa kwenguva refu nemaPPIs.
Bvunza wako mupi wezvehutano nezve zvimwe zvinogona kunyeverwa uye matanho usati watora PPI.
Inowanzo bvunzwa mibvunzo nezve Protonix vs. Nexium
Chii chinonzi Protonix?
Protonix inonyorwa-chete PPI mishonga iyo inonyanya kushandiswa kurapa erosive esophagitis inosangana neGERD. Protonix inowanikwa sekunonoka-kuburitsa piritsi uye kumiswa kwemvura. Zita rakajairika reProtonix ndi pantoprazole.
Chii chinonzi Nexium?
Nexium mushonga wePPI uyo unoshandiswa kurapa acid Reflux uye chirungurira, pamwe ne erosive esophagitis inosangana neGERD. Inowanikwa uine mushonga kana pamusoro pekambani. Nexium inonyanya kuuya sekunonoka-kuburitsa kapuleti kana kumiswa kwemvura. Iro zita rekuti Nexium isomeprazole.
Protonix neNexium zvakafanana here?
Protonix neNexium mishonga miviri yePPI inogona kubata GERD, hypersecretory mamiriro, uye peptic ulcers. Nekudaro, izvo zvine zvakasiyana zvinoshandiswa zvinoshandiswa uye zvinouya nenzira dzakasiyana. Protonix ine pantoprazole uye Nexium ine esomeprazole. Protonix inogona kubata GERD muvakuru uye vana vane makore mashanu uye nepamusoro apa Nexium inogona kubata GERD muvanhu vakuru, vana, uye vacheche vane mwedzi mumwe kana kupfuura.
Protonix kana Nexium iri nani here?
Protonix neNexium zvakafanana mukubudirira. Iyo yakakodzera kwazvo PPI ichagadziriswa zvichienderana nezera, kurapwa mamiriro, mutengo, inishuwarenzi, uye mimwe mishonga iri kutorwa.
Ndinogona here kushandisa Protonix kana Nexium nepamuviri?
Protonix kana Nexium inogona kuva yakachengeteka kutora paunenge uine pamuviri. Nekudaro, iwo anofanirwa kushandiswa chete kana mabhenefiti akakunda njodzi. Parizvino, hapana zvakakwana zvidzidzo zvekutaridza kuti Protonix kana Nexium yakachengeteka zvachose kushandisa panguva yekuzvitakura. Bvunza mupi wezvehutano nezvezvehutano hwakanakisisa kurapwa kweGERD uchiri nepamuviri.
Ndinogona here kushandisa Protonix kana Nexium nedoro?
Nepo doro risingazivikanwe kuti rinobatana neProtonix kana Nexium, inogona kukuvadza asidhi Reflux uye yekucheresa zviratidzo mune vamwe vanhu. Kunwa doro kunogona kuchengetedzeka zvine mwero uchitora Protonix kana Nexium, asi kazhinji haina kukurudzirwa.
Ndeipi inonyanya kushanda proton pombi inhibitor?
Iyo inoshanda kwazvo PPI inoenderana nemamiriro ari kurapwa, kuyerwa kwePPI, uye mimwe mishonga munhu angave ari kutora. Mutengo wePPI unofanirwawo kutorwa mukufungwa kana uchifunga sarudzo inoshanda.
Chii chandinga tore pane Nexium?
Nexium (esomeprazole) ipurotoni pombi inhibitor. Dzimwe proton pump inhibitors dzinosanganisira Prilosec (omeprazole), Prevacid (lansoprazole), Aciphex (rabeprazole), uye Protonix (pantoprazole). Kana zviratidzo zveGERD zvikasavandudzika nePPI, mupi wezvehutano anogona kukurudzira H2 blocker mishonga pachinzvimbo. Mienzaniso yeH2 blockers inosanganisira Pepcid (famotidine), Zantac (ranitidine), uye Tagamet (cimetidine).
Nexium inogona kuita kuti reflux iwedzere?
Nexium inoshandiswa kurapa acid Reflux. Kurega Nexium kurapwa pakutanga pane kukurudzirwa nemupi wezvehutano kunogona kutungamira kudzoka kwezviratidzo zve reflux. Nexium inogona kusashanda zvakafanana kune wese munhu. Kana zviratidzo zvikasavandudzika neNexium, dzimwe nzira dzekurapa dzinogona kukurudzirwa.
