Ozempic vs. Trulicity: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Kana iwe uine Type 2 chirwere cheshuga, wako endocrinologist kana wekutanga wezvehutano mupi anogona kunge akataura nezve kushandisa jekiseni mishonga kudzora yako yeropa shuga. Ozempic (semaglutide) uye Trulicity (dulaglutide) ndiwo mazita maviri anozivikanwa majekiseni anoshandiswa mukurapa rudzi rwechipiri chirwere cheshuga. Ozempic inogadzirwa naNovo Nordisk, uye Trulicity inogadzirwa naEli Lilly uye Kambani. Mishonga iyi miviri inogamuchirwa neDFA. Ivo vanoiswa muboka remishonga inonzi GLP-1 receptor agonists (glucagon-kunge peptide agonists).
Ozempic uye Trulicity mishonga inobaya chirwere cheshuga — asi kwete jekiseni . Ivo vanoshanda nekusimudzira insulin kuchengetedzwa uye kudzikisa glucagon secretion, nokudaro vachideredza mazinga eruglucose eropa. Iyi mishonga zvakare inononoka kunonoka gastric kupera, iyo inobatsira kudzora zvese chishuwo uye postprandial (mushure mekudya) huwandu hweshuga yeropa. Ivo vanobatsira kuonda kurasikirwa nekubatsira kudzikisa huremu hwemuviri.
Ozempic uye Trulicity zvakare inobatsira nehemoglobin A1c kudzikira (HbA1c), inova chiyero cheshuga kudzora kupfuura nguva. Kunyangwe ese ari maviri mishonga ari GLP-1 agonists, iwo ane misiyano, iyo yatichakurukura pazasi.
Ndeupi musiyano mukuru pakati peOzempic neTrulicity?
Ozempic uye Trulicity vari mukirasi yezvinodhaka inonzi GLP-1 agonists, kana glucagon-senge peptide agonists. Mishonga iyi yose inowanikwa muzita rezita chete. Chinhu chinoshanda muOzempic is semaglutide, uye chinhu chinoshanda muTrulicity ndi dulaglutide. Nekudaro, kana mushonga izvozvi zviripo mune generic fomu. Ose madhiragi anowanikwa mune fomu jekiseni fomu. Nemutero wega wega wevhiki, mushonga unopinda mukati medumbu, chidya, kana ruoko rwepamusoro.
| Misiyano mikuru pakati peOzempic uye Trulicity | ||
|---|---|---|
| Ozempic | Trulicity | |
| Kirasi yemishonga | Glucagon-yakaita peptide 1 (GLP-1) receptor agonist | Glucagon-yakaita peptide 1 (GLP-1) receptor agonist |
| Brand / generic chinzvimbo | Brand | Brand |
| Chii chinonzi generic zita? | Semaglutide | Dulaglutide |
| Ndeapi mafomu (s) ayo mushonga unouya? | Peni jekiseni jekiseni subcutaneous | Peni jekiseni jekiseni subcutaneous |
| Ndeipi muyero wakajairwa? | Kutanga dosi: 0.25 mg kamwe pasvondo. Mushure memasvondo mana, wedzera dose kusvika ku0,5 mg kamwe pasvondo. Inogona kuwedzera kusvika 1 mg kamwe pasvondo mushure memasvondo mana kana kuwedzerwa glycemic control kuchidikanwa. Maximum yakakurudzirwa dosi ndeye 1 mg vhiki nevhiki | Kutanga dosi: 0.75 mg kamwe pasvondo. Inogona kuwedzera kusvika 1.5 mg kamwe pasvondo kana yakawedzera glycemic control ichidikanwa. Maximum yakakurudzirwa dosi ndeye 1.5 mg kamwe pasvondo |
| Yakareba sei iyo yekurapa? | Zvinosiyana | Zvinosiyana |
| Ndiani anowanzoshandisa mushonga? | Vakuru vane makore gumi nemasere zvichikwira | Vakuru vane makore gumi nemasere zvichikwira |
Unoda yakanakisa mutengo paTrulicity?
Saina kuti Trulicity mutengo chenjedzo uye uwane kuti kana mutengo wachinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu anorapwa neOzempic uye Trulicity
Ose Ozempic uye Trulicity ane zviratidzo zviviri. Chiratidzo chekutanga ndechekuvandudza glycemic control muvanhu vakuru vane Type 2 chirwere cheshuga (pamwe chete nekudya uye kurovedza muviri). Chiratidzo chechipiri kudzikisa njodzi yezviitiko zvikuru zvemoyo (sitiroko, chirwere chemwoyo, kufa kwemoyo) kune varwere vane Type 2 cheshuga uye chirwere chemwoyo.
| Mamiriro | Ozempic | Trulicity |
| Batanidza kune kudya uye kurovedza muviri kuvandudza glycemic kutonga mune vanhu vakuru vane Type 2 chirwere cheshuga mellitus (DM) | Ehe | Ehe |
| Kuderedza njodzi yezviitiko zvakakomba zvemoyo zvevanhu vakuru vane Type 2 DM uye chirwere chemoyo | Ehe | Ehe |
Ko Ozempic kana Trulicity inoshanda zvakanyanya here?
Muchikamu 3b kliniki kuyedzwa . Zvisinei, zvakakosha kuziva kuti chidzidzo chacho chakaitwa naNovo Nordisk, mugadziri weOzempic. Hapana zvimwe zvidzidzo zvemusoro-kusvika-musoro zvakaitwa zvichifananidza Ozempic neTrulicity.
Mushonga unoshanda kwazvo kwauri unonyatso sarudzwa neako endocrinologist kana wekutanga wezvehutano mutapi, uyo anogona kufunga nezve ako mamiriro ezvehutano (s) uye nhoroondo yezvekurapa, pamwe nemimwe mishonga yaunotora.
Kuvhavha uye mutengo kuenzanisa kweOzempic vs. Trulicity
Ose Ozempic uye Trulicity akafukidzwa neinishuwarenzi mazhinji uye Medicare Chikamu D zvirongwa. Tarisa neyako inishuwarenzi mupi kuti uwane yakatarwa / mari yechirongwa chako.
Chirevo cheOzempic chinosvika madhora mazana mapfumbamwe nemakumi mapfumbamwe. Unogona kuitenga ne $ 711 neSingleCare Ozempic discount coupon.
Tsamba yeTrulicity inogona kumhanyisa madhora zviuru zviviri. Unogona kusevha neSingleCare uye ubhadhare $ 1,432 kuma pharmacies ari kutora chikamu.
| Ozempic | Trulicity | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Hongu (kazhinji) | Hongu (kazhinji) |
| Inowanzo kufukidzwa neMedare Chikamu D? | Hongu (kazhinji) | Hongu (kazhinji) |
| Standard muyero | 1 peni yakafetwa (inoburitsa 0.25 mg, 0.5 mg, kana 1 mg pajekiseni) | 1 bhokisi re4, imwechete-dhizaini mapeni (0.75 mg kana 1.5 mg pa 0.5 ml jekiseni) |
| Chaizvoizvo Medicare Chikamu D copay | $ 25- $ 888 | $ 25- $ 873 |
| SingleCare mutengo | $ 711 | $ 1,432 |
Zvakajairika mhedzisiro mhedzisiro yeOzempic vs. Trulicity
Mhedzisiro inowanzoitika yeOzempic ndeyekusvotwa, kurutsa, manyoka, kurwadziwa mudumbu, uye kupatira. Mhedzisiro inowanzoitika yeTrulicity kusvotwa, kurutsa, manyoka, kurwadziwa mudumbu, kuzvimbirwa, kushomeka kwekuda kudya, kuneta uye kuzvimbirwa. Hypoglycemia (yakaderera ropa shuga) inogona kuitika nemushonga. Iyi haisi rondedzero izere yemhedzisiro. Mimwe mhedzisiro yakaipa inogona kuitika. Bvunza wako mupi wezvehutano kuti uwane yakazara rondedzero yemhedzisiro
| Ozempic | Trulicity | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Nausea | Ehe | 15.8-20.3% * | Ehe | 12.4-21.1% * |
| Kusvipa | Ehe | 5.0-9.2% | Ehe | 6.0-12.7% |
| Manyoka | Ehe | 8.5-8.8% | Ehe | 8.9-12.6% |
| Marwadzo emudumbu | Ehe | 5.7-7.3% | Ehe | 6.5-9.4% |
| Kuzvimbirwa | Ehe | 3.1-5.0% | Ehe | 3.7-3.9% |
| Hypoglycemia (yakaderera ropa shuga) | Ehe | Zvinosiyana | Ehe | Zvinosiyana |
| Kuderedza kudya | Ehe | % haina kutaurwa | Ehe | 4.9-8.6% |
| Kuneta | Ehe | > 0.4% | Ehe | 4.2-5.6% |
| Dyspepsia (indigestion) | Ehe | 2.7-3.5% | Ehe | 4.1-5.8% |
* Inoenderana nedosi
Kwayaka: DailyMed ( Ozempic ), Zuva Nezuva ( Trulicity ).
Kubatana kwezvinodhaka kweOzempic vs. Trulicity
Kushandisa Ozempic kana Trulicity ine insulin kana insulin secretagogues (mamwe emuromo mishonga yeshuga mishonga) inogona kuwedzera njodzi ye hypoglycemia. Kana iwe ukatora uyu mubatanidzwa wemishonga, wako wekunyora anowanzo gadzirisa dosing ye insulini yako kana mushonga wemuromo. Zvakare, nekuti Ozempic kana Trulicity inokonzeresa kunonoka gastric kubvisa, kunwa kwemuromo mishonga kunogona kukanganisa kana kutorwa panguva imwe chete. Muzvidzidzo, kusangana uku hakuna kuitika kune degree rakakodzera rekiriniki; zvisinei, izano rakanaka kubvunza mupi wezvehutano nezvenguva yemishonga yako.
Mishonga ine yakamanikana yekurapa index inofanira kunyanya kuongororwa. Izvi zvinosanganisira zvinodhaka uko kune hwindo diki pakati pekurapa maitiro uye huturu hwakadai seCoumadin (warfarin), Lanoxin (digoxin), uye mishonga yekubvuta.
Iri harisi runyorwa ruzere rwekubatana kwezvinodhaka. Bvunza wako mupi wezvehutano kuti uwane yakazara runyorwa rwekudyidzana zvinodhaka.
| Zvinodhaka | Kirasi yemishonga | Ozempic | Trulicity |
| Meglitinides (nateglinide, repaglinide) Sulfonylureas (glimepiride, glipizide, glyburide) | Insulin zvakavanzika | Ehe | Ehe |
| Basaglar Humalog Lantus Levemir Novolog Toujeo Tresiba | Insulin | Ehe | Ehe |
| Oral mishonga | Oral mishonga | Hongu (pamwe) | Hongu (pamwe) |
Yambiro yeOzempic uye Trulicity
Nekuti mishonga yese iri mukirasi imwe chete yezvinodhaka, yambiro uye matanho anonyanya kufanana. Iwe unozogamuchira gwara remushonga chero nguva iwe paunozadza mushonga weOzempic kana Trulicity, iyo inopfuura pamusoro pemhedzisiro uye yambiro.
Iko kune yambiro yebhokisi yeOzempic uye Trulicity, inova yambiro yakakomba inodiwa neDFA. Mumakonzo, Ozempic kana Trulicity inokonzera thyroid C-cell tumors, kusanganisira MTC (medullary thyroid carcinoma). Hazvizivikanwe kana izvi zvichikonzerwa nevanhu. Zvakare, varwere vane nhoroondo (kana nhoroondo yemhuri) yeMTC kana neakawanda endocrine neoplasia syndrome mhando 2 (MEN 2) havafanirwe kutora Ozempic kana Trulicity.
Dzimwe yambiro dzinosanganisira:
- Acute pancreatitis inogona kuitika. Varwere vanofanirwa kunyatso cherechedzwa zviratidzo nezviratidzo zvepancreatitis, kusanganisira zvinoramba zvichirwadza zvakanyanya mudumbu, izvo zvinogona kupenya kumusana, uye zvinogona kana kusaperekedzwa nekurutsa. Kana pancreatitis iri kufungidzirwa, Ozempic kana Trulicity kurapwa kunofanira kumiswa uye kwakakodzera manejimendi inofanirwa kutangwa. Kana pancreatitis yakasimbiswa, mushonga wacho haufanire kutangwazve.
- Dhiyabhorosi retinopathy zvinetso zvinogona kuitika-iyo njodzi yakakwira kune varwere vane nhoroondo yeshuga retinopathy. Kukurumidza kugadzirisa kweshuga yeshuga yekudzora kunogona kusanganiswa nekuwedzera kwechinguvana kwechirwere cheshuga retinopathy. Varwere vanofanirwa kuongororwa.
- Ozempic kana Trulicity matanga haafanire kugoverwa pakati pevarwere, kunyangwe tsono ikashandurwa, nekuda kwenjodzi yakawedzera yekutapukira kwezvirwere zvinotakurwa neropa. Trulicity peni mapena-anoshandisa-imwe peni yeTrulicity inoshandiswa kamwe chete.
- Shuga yeropa yakadzika inogona kuitika apo Ozempic kana Trulicity inotorwa ne insulin kana insulin secretagogue mishonga. Dose kugadzirisa insulin kana insulin secretagogue inogona kudiwa.
- Kukuvara kwetsvo kwakanyanya uye kuwedzera kwekusingaperi kweitsvo kukundikana kunogona kuitika, izvo zvingangoda dialysis. Zviratidzo zvinogona kusanganisira kuda kurutsa, kurutsa, manyoka, uye / kana kupera mvura mumuviri. Itsvo basa rinofanira kuongororwa.
- Yakakomba hypersensitivity reaction (anaphylaxis kana angioedema) yakataurwa. Kana izvi zvikaitika, Ozempic kana Trulicity inofanira kumiswa. Varwere vane yapfuura hypersensitivity reaction havafanire kushandisa Ozempic kana Trulicity.
- Nekuda kwenjodzi ingangoitika kumucheche, Ozempic kana Trulicity kazhinji haifanire kushandiswa mukuzvitakura, kunze kwekunge mabhenefiti akakunda njodzi. Mubatsiri wako wehutano angangowana imwe nzira yekurapa yekushandisa.
- Pamusoro pezvo, ruzivo rwekugadzira zvinhu rweTrulicity rwunoti mushonga unogona kuve unosanganisirwa nemaitiro emudumbu (GI), dzimwe nguva akaomarara. Nekuti Trulicity haina kuongororwa mune varwere vane chirwere chakakomba cheGI, kusanganisira chakakomba gastroparesis, haina kukurudzirwa kuti ishandiswe mune ava varwere.
Inowanzo bvunzwa mibvunzo nezve Ozempic vs. Trulicity
Chii chinonzi Ozempic?
Ozempic iri kamwe-vhiki inopihwa jekiseni mishonga inoshandiswa mukurapa Type 2 chirwere cheshuga. Inozivikanwa seGLP-1 receptor agonist.
Chii chinonzi Trulicity?
Trulicity jekiseni kamwe-vhiki rinoshandiswa pakurapa Type 2 chirwere cheshuga. Iyo GLP-1 receptor agonist.
Ko Ozempic uye Trulicity zvakafanana here?
Ozempic uye Trulicity vese vari mukirasi yemishonga inonzi GLP-1 receptor agonists. Ivo vakafanana chaizvo, asi kwete zvakangofanana. Ruzivo rwuri pamusoro rwunopinda zvakadzama nezvemushonga wega wega. Mimwe mishonga iri mukirasi yeGLP-1 receptor agonist inosanganisira Victoza (liraglutide), Byetta (exenatide), Bydureon (yakawedzera-kuburitsa exenatide), uye Adlyxin (lixisenatide). Iko kune zvakare yemumuromo semaglutide piritsi inowanikwa, ine imwecheteyo chinhu muOzempic. Hwendefa remuromo unonzi Rybelsus.
Ko Ozempic kana Trulicity zvirinani here?
Ose madhiragi anoita kunge akafanana mukubudirira maererano nekuwana glycemic control uye kubatsira kudzikisa huremu. Chimwe chidzidzo (ona pamusoro) chakafananidza mishonga iyi miviri uye vakawana Ozempic iri nani zvishoma. Asi zvakakosha kuti uzive kuti kudzidza kwakaitwa nemugadziri weOzempic. Bvunza wako mupi wezvehutano kuti uone kana Ozempic kana Trulicity ingave iri yakakodzera mishonga iwe.
Ndinogona here kushandisa Ozempic kana Trulicity ndichiri nepamuviri?
Iko kune mashoma data paOzempic uye Trulicity mukuzvitakura. Zvinogona kukonzera kukuvara kwechibereko. Bvunza wako mupi wezvehutano kuti akutungamire. Kana iwe uri kutotora Ozempic kana Trulicity uye uone kuti iwe une nhumbu, bata wako OB-GYN nekukurumidza kuti utungamirirwe.
Ndinogona here kushandisa Ozempic kana Trulicity nedoro?
Zvakanakisa kunwa doro uchishandisa Ozempic kana Trulicity. Doro rinogona kukonzera shuga yakadzika muropa, uye Ozempic kana Trulicity inogona kukonzeresa shuga yeropa zvakare. Iko kusanganisa kunogona kukonzera kwakakomba kana kwenguva refu yakaderera ropa shuga.
Ozempic yakafanana nemetformin here?
Kwete. Ozempic jekiseni kana metformin mushonga wemumuromo unogona kushandiswa mukubatana ne insulin uye / kana imwe mishonga yemumuromo, pamwe nekudya uye kurovedza muviri, pakurapa Type 2 chirwere cheshuga. (Ozempic haina kuratidzwa pakurapa kweType 1 chirwere cheshuga kana kurapwa kwechirwere cheshuga ketoacidosis).
Zvinotora nguva yakareba sei kuti Ozempic itange kushanda?
Ukangobaya Ozempic, iwo mwero wepamusoro unosvitswa mune rimwe chete kana mazuva matatu. Zvisinei, zvinogona kutora nguva yakareba kuti zvione zvainoita. Mushonga wakajairika ndewokutangira pa0.25 mg kamwe pavhiki uye mushure memavhiki mana, iwe uchawedzera muyero kusvika ku0.5 mg kamwe pasvondo. Kana mushure memamwe masvondo mana, iwe uchizoda kutonga kwakawanda, iwe unowedzera kusvika 1 mg kamwe pasvondo. Anopa hutano hwako anokutungamira pane iwo muyero wakakodzera.
Ozempic inokonzera kunetseka here?
Iyo Ozempic ruzivo rwemugadziri haina kunyora kushushikana senge divi mhedzisiro. Nekudaro, Ozempic inogona kukonzera hypoglycemia (yakaderera ropa shuga), uye kushushikana kunogona kuve chimwe chezviratidzo zvakawanda zveshuga muropa. Kana iwe uri paOzempic uye uine kusagadzikana kwausati wamboona, bvunza wako mupi wezvehutano.
