Minocycline vs doxycycline: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Minocycline uye doxycycline ndiwo tetracycline mishonga inorwisa mabhakitiriya inowanzo shandiswa pakurapa mburwa uye zvimwe zvinowanzoitika chirwere cheganda chinetso. Aya maantibayoti anofukidza huwandu hwakasiyana hwemhando dzehutachiona dzinovaita kuti dzibudirire mune dzakasiyana dzimwe nzira dzekutapukira futi. Acne ndiyo inonyanya kuzivikanwa ganda mamiriro muAmerica. Vanopfuura mamirioni makumi mashanu emaAmerican vanotambura neacne gore rega. Nepo zvese minocycline uye doxycycline zvichikwanisa kunyatso kurapa acne, pane misiyano yakakura pakati pemishonga iyi miviri.
Ndeupi mutsauko mukuru pakati pe minocycline ne doxycycline?
Minocycline mushonga unorwisa mabhakitiriya uri weboka remushonga rinozivikanwa se tetracyclines. Inowanzo shandiswa kurapa acne, rosacea, chirwere chekufema, hutachiona hwehutachiona, uye zvimwe zvirwere zvepabonde. Minocycline inopindirana neprotein synthesis nekusunga kune mRNA ribosome yakaoma. Gram-positive mabhakitiriya anonyanya kubatwa ne minocycline kupfuura gram-negative bacteria.
Minocycline inowanikwa seyemumuromo-kuburitsa makapuleti uye mapiritsi mu50 mg, 75 mg, uye 100 mg simba. Inowanikwawo mune akawedzera-kuburitswa makapisi uye mapiritsi. Minocycline inowanikwawo sehupfu hunogadziriswazve jekiseni pamwe neyemusoro-chete yekushandisa furo.
Doxycycline mushonga unorwisa mabhakitiriya iyo zvakare iri yekirasi yetetracycline mishonga inorwisa mabhakitiriya. Doxycycline inoratidzirwa kurapa acne, rosacea, hutachiona hwekufema, uye isiri-gonococcal urethritis uye cervicitis. Doxycycline inoshanda zvakafanana kune minocycline, nekudzivirira mapuroteni mukati mebacteria cell. Nekudaro, doxycycline inoshanda kurwisa zvese zviri zviviri gram-yakanaka uye gramu-isina mabhakitiriya.
Doxycycline inowanikwa mune maviri mafomu emunyu, doxycycline hyclate uye doxycycline monohydrate. Doxycycline hyclate ndiyo inonyanya kusungunuka yemhando mbiri dzemunyu. Doxycycline hyclate inowanikwa mumahwendefa ekukurumidza-kuburitsa mune masimba e20 mg, 50 mg, 75 mg, 100 mg, uye 150 mg, macompule-anosunungura macapsule, uye sekumiswa kwemuromo.
Doxycycline hyclate inowanikwawo mukunonoka-kuburitsa makapuleti uye mapiritsi. Iyo yekupedzisira fomu ye doxycycline hyclate ipoda inofanirwa kugadziriswazve jekiseni.
Doxycycline monohydrate inowanikwa seinoburitsa kapuleti, bi-phasic kuburitsa piritsi, pamwe nekumiswazve kwemuromo mune 25 mg / 5 ml wevasungwa.
| Misiyano mikuru pakati pe minocycline uye doxycycline | ||
|---|---|---|
| Minocycline | Doxycycline | |
| Kirasi yemishonga | Tetracycline mishonga inorwisa mabhakitiriya | Tetracycline mishonga inorwisa mabhakitiriya |
| Brand / generic chinzvimbo | Brand uye generic inowanikwa | Brand uye generic inowanikwa |
| Chii chinonzi zita rechiratidzo? | Dynacin, Minocin, Ximino, Solodyn | Vibramycin, Doryx, Targadox, Acticlate, Periostat, Monodox, Adoxa, Oracea |
| Ndeapi mafomu (s) ayo mushonga unouya? | Mahwendefa epakarepo uye akawedzerwa-kuburitswa uye makapisi, jekiseni, furo remusoro | Pakarepo uye akawedzera-kusunungura mahwendefa uye macapsule, emuromo emvura, jekiseni |
| Ndeipi muyero wakajairwa? | 100 mg zuva nezuva | 100 mg kaviri pazuva |
| Inguva yakareba sei kurapwa kwacho? | Mazuva makumi matatu | Mazuva gumi |
| Ndiani anowanzoshandisa mushonga? | Vana vane makore 8 ekuberekwa uye vakuru, vachiri kuyaruka, vakuru | Vana vane makore 8 ekuberekwa uye vakuru, vachiri kuyaruka, vakuru |
Mamiriro ezvinhu anorapwa ne minocycline vs. doxycycline
Minocycline uye doxycycline mugove wekuratidzira kweanowanzoitika hutachiona maitiro, asi zvakare imwe neimwe ine yakasarudzika mashandisirwo mukiriniki maitiro. Acne rosacea uye acne vulgaris ndiwo maviri ekushandisa zvakanyanya kune ese minocycline uye doxycycline. Acne vulgaris inogona kuitika muviri wese uye inowanzoitika kune vechidiki. Iyo inogona kuunza nemhando dzakasiyana dzemaronda anosanganisira madema, pustules, uye ma nodule. Acne rosacea inowanzoitika kune vanhu vane makore makumi matatu zvichikwira uye inowanzo kuve yakasarudzika kumeso. Chimwe nechimwe chezvirwere izvi zvinotapukira chingangoda remuromo maantibiotic kurapa kuti uwane kuregererwa kwezviratidzo.
Minocycline inoratidzwa mune meningococcal prophylaxis pamwe nekurapa meningitis. Inotakurawo chiratidzo chekurapa kwechlamydial hutachiona hweziso.
Doxycycline inoratidzwa muprophylaxis yezvose anthrax nedenda. Doxycycline yakave zvakare yakaratidza kushanda muvanhu-yakawanikwa pneumonia.
Iyi inotevera runyorwa inogona kusasanganisira mashandisiro ese e minocycline uye doxycycline. Bvunza wako mupi wezvehutano nemibvunzo nezve chaiyo yekushandisa.
| Mamiriro | Minocycline | Doxycycline |
| Acne rosacea | Ehe | Ehe |
| Acne vulgaris | Ehe | Ehe |
| Bhakitiriya conjunctivitis | Kwete | Ehe |
| Chlamydia | Ehe | Ehe |
| Chlamydial conjunctivitis | Ehe | Kwete |
| Gonorrhea | Ehe | Ehe |
| Malaria prophylaxis | Kwete | Ehe |
| Gungwa-hutachiona ne listeria | Ehe | Kwete |
| Necrotizing ulcerative gingivitis | Ehe | Ehe |
| Asiri-gonococcal urethritis (NGU) | Ehe | Ehe |
| Q fivha | Ehe | Ehe |
| Kudzokorora fivhiri | Ehe | Ehe |
| Rickettsialpox | Ehe | Ehe |
| Rocky Mountain yakaonekwa nefivha | Ehe | Ehe |
| Tsvina typhus | Kwete | Ehe |
| Sinusitis | Kwete | Ehe |
| Ganda uye ganda chimiro hutachiona | Ehe | Ehe |
| Urinary turakiti hutachiona (URI) | Ehe | Ehe |
| Rheumatoid arthritis | Kunze-chitaridzi | Kwete |
Iri harisi runyorwa rwakakwana rwekurapa.
Minocycline kana doxycycline inoshanda zvakanyanya here?
Kubudirira kwe minocycline kana doxycycline kunoenderana nechiratidzo chiri kuenzaniswa. Chimwe chezvinyanya kuwiriranwa zvinoratidza izvi zviviri zvinodhaka acne acne rosacea. A randomised inodzorwa kuyedzwa , yakaburitswa muna2017, yakatsvaga kuenzanisa kushanda pamwe nekuchengetedzeka kwemishonga iyi miviri pakurapa rosacea. Vane makumi masere varwere vane rosacea yakapfava kusvika kune yakaoma vaisarudzika kuita doxycycline 40 mg kana minocycline 100 mg. Mhedzisiro yeongororo iyi yakawana kuti mamakisi ekuvandudza aive ari nani zvakanyanya kuboka re minocycline. Boka re minocycline zvakare raive nekudzokedzana kushoma muzviratidzo uye raive nenguva yakareba yekuregererwa. Pakange pasina musiyano wakakosha mukuchengeteka pakati pemishonga iyi miviri.
TO kuongorora kwakarongeka yezvinyorwa zvakaitwa zvakare kuenzanisa uye kuyedza kuchengetedzeka uye zviitiko zvakashata pakati pe minocycline ne doxycycline. Ongororo yakatarisa pamakore gumi nemashanu e data. Doxycycline yakatemwa katatu kazhinji pane minocycline. Nepo zviitiko zvakashata zvechero zvinodhaka zvakaderera, doxycycline yaibatanidzwa nezviitiko zvishoma zvakashata pane minocycline.
Kuvhavha uye mutengo kuenzanisa kweminocycline vs. doxycycline
Minocycline mushonga wekunyorerwa mushonga unowanzo kuvharwa nezvose zviri zviviri zvekutengeserana uye zveMedare zvinorayirwa zvirongwa zvemishonga Mutengo wekunze-muhomwe weyakajairwa minocycline mushonga unogona kunge ungangoita madhora zana nemakumi matatu. Nekoponi kubva kuSingleCare, mutengo unodonhera kusvika pamadhora makumi matatu nematatu.
Doxycycline mushonga wekunyorerwa mushonga uyo unowanzo kuvharwa nezvirongwa zvekutengeserana uye zveMedicare zvemushonga. Mutengo wekunze kwehomwe we doxycycline hyclate unogona kudarika $ 200. Mutengo une SingleCare coupon unogona kunge wakaderera kunge $ 31.
| Minocycline | Doxycycline | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 30, 100 MG capsules | 20, 100 MG capsules |
| Chaizvoizvo Medicare copay | $ 10 kana pasi | $ 10 kana pasi |
| SingleCare mutengo | $ 39- $ 54 | $ 31- $ 55 |
Zvakajairika mhedzisiro mhedzisiro ye minocycline vs. doxycycline
Minocycline uye doxycycline imwe neimwe ine tsika yekukonzera gastrointestinal mhedzisiro mhedzisiro inosanganisira kusvotwa, kurutsa, manyoka, uye anorexia. Iyi mhedzisiro inogona kuve yakaoma kutsungirira kwenguva yakareba uye inogona kuve nemhosva yekumisa nguva isati yasvika yekurapa nekuda kwekusagadzikana.
Minocycline yave ichibatanidzwa nezviitiko zvisingawanzoitika zvechiropa kutadza uye hepatitis. Varwere vane kuzivikanwa kwekuremara kwehepatic vanofanirwa kudzivirira minocycline kana kuongororwa zvakanyanya pavanotora.
Doxycycline yakabatanidzwa neyakajairika asi yakakomba chiitiko chakashata cheStevens-Johnson syndrome. SJS inogona kuunza ine diki yepepuru kana tsvuku makwapa, mablisters, ganda rinobvaruka, uye / kana kuputika. Icho chiitiko chakakomba kwazvo chinoda kurapwa nekukurumidza.
Iyi inotevera rondedzero haina kuitirwa kuti ive izere runyorwa rweakashata zviitiko. Ndokumbirawo ubvunze wemishonga, chiremba, kana mumwe chiremba wezvekurapa kuti uwane yakazara rondedzero yemhedzisiro inogona kuitika.
| Minocycline | Doxycycline | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Anorexy | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Nausea | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Kusvipa | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Manyoka | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Glossitis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Dysphagia | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Enterocolitis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Pancreatitis | Ehe | Hazvina kutsanangurwa | Kwete | n / a |
| Wedzera mumakemikari echiropa | Ehe | Hazvina kutsanangurwa | Kwete | n / a |
| Hepatitis | Ehe | Hazvina kutsanangurwa | Kwete | n / a |
| Chiropa kutadza | Ehe | Hazvina kutsanangurwa | Kwete | n / a |
| Mapundu | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Exfoliative dermatitis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Urticaria | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Edema | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Pericarditis | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Anemia | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Thrombocytopenia | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Neutropenia | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Stevens-Johnson chirwere | Kwete | n / a | Ehe | Hazvina kutsanangurwa |
Kwayaka: Minocycline ( Zuva Nezuva ), Doxycycline ( Zuva Nezuva )
Kubatana kwezvinodhaka kweminocycline vs. doxycycline
Minocycline uye doxycycline ese ari maviri maantibhakitiriya kubva mukirasi imwechete yetetracyclines, uye yavo runyorwa rweanogona kusangana madhiragi akafanana. Kazhinji antacids ine aluminium hydroxide, yakadai seGaviscon, inogona kukanganisa kunwa kweminocycline uye doxycycline. Izvi zvinogona kutungamira mukudzikira kwekushanda kweminocycline uye doxycycline. Kuti udzivise kusangana uku, antacids haifanire kutorwa nemishonga iyi. Sezvineiwo, pangave neanoda maawa maviri pakati pekutungamira kweantacid uye ingave minocycline kana doxycycline.
Tetracycline antibiotic yakadai se minocycline uye doxycycline inopindirana nehutachiona hwechimwe chikamu chinowanzoitwa maantibayoti, penicillin. Kirasi iyi inosanganisira anowanzoitwa maantibhakitiriya akadai amoxicillin uye penicillin. Pane zviitiko apo varwere vangangoda kutora anopfuura maantibayoti imwe panguva, uye zvakakosha kuti uzive kubatana uku pakusarudza marapirwo.
Iyi inotevera rondedzero haina kuitirwa kuti ive izere runyorwa rwekudyidzana zvinodhaka. Zvakanakisisa kubvunza wako mupi kana wemishonga kune yakazara runyorwa.
| Zvinodhaka | Kirasi yemishonga | Minocycline | Doxycycline |
| Aluminium hydroxide Bismuth salicylate Magnesium hydroxide Sodium bicarbonate | Antacids | Ehe | Ehe |
| Amoxicillin Ampicillin Carbenicillin Dicloxacillin Penicillin Piperacillin | Penicillin mishonga inorwisa mabhakitiriya | Ehe | Ehe |
| Calcium kabhoni Calcium acetate Karusiyamu chloride Karusiyamu gluconate | Calcium makomponi | Ehe | Ehe |
| Zinc munyu | Zinc inowedzera | Ehe | Ehe |
| Cholestyramine Colesevelam Colestipol | Bheri asidhi sequestrant | Ehe | Ehe |
| Didanosine | Antiretroviral | Ehe | Ehe |
| Digoxin | Antiarrhythmic | Ehe | Ehe |
| Drospirenone, Estradiol, progestin | Mishonga yekudzivirira | Ehe | Ehe |
| Quinapril | Angiotensin inoshandura enzyme (ACE) inhibitor | Ehe | Ehe |
| Iron Iron munyu Iron sucrose Sodium ferric gluconate yakaoma Ferric pyrophosphate citrate | Iron inowedzera | Ehe | Ehe |
| Isotretinoin | Retinoid | Ehe | Ehe |
| Lomitapide | Microsomal triglyceride transfer protein (MTP) inhibitor | Ehe | Ehe |
| Magnesium Magnesium Citrate Magnesium munyu | Magnesium inowedzera / Laxatives | Ehe | Ehe |
| Methotrexate (MTX) | Folate antimetabolite / immunosuppressant | Ehe | Ehe |
| Pyridostigmine | Parenteral cholinesterase inhibitor | Ehe | Ehe |
Yambiro dze minocycline uye doxycycline
Minocycline uye doxycycline zvakakamurwa neKudya neDrug Administration (FDA) seboka D chinodhaka, zvichireva kuti kune humbowo hwakanaka hwekuti ingangove njodzi yemwana. Iyi mishonga inofanirwa kushandiswa chete kana paine njodzi kuhupenyu kuna amai. Pane humbowo hwehunhu hwakashata pane kukura kwemabhonzo emucheche.
Iko kushandiswa kwetetracycline mishonga inorwisa mabhakitiriya panguva yekukura kwemeno kunogona kukonzera kusingaperi kwemazino kuva yero, pfumbu, kana shava ruvara. Mhedzisiro iyi yakajairika nekushandisa kwenguva refu, kunyangwe zvave zvichionekwa nekushandisa kwenguva pfupi zvakare. Kana zvichikwanisika, kushandiswa kwetetracycline mishonga inorwisa mabhakitiriya kunofanirwa kudzivirirwa mukati mehafu yekupedzisira yepamuviri kuburikidza nemakore gumi nemasere pazvinogoneka.
Minocycline yanga ichibatanidzwa neDrash Rash neEosinophilia uye Systemic Syndrome (DRESS) syndrome. Izvi zvinoonekwa nekumhanyisa, fivhiri, uye kukuvara kwemitezo, kazhinji chiropa neitsvo. Dzimwe zviitiko zvinogona kuuraya.
Tetracyclines yakabatanidzwa ne photosensitivity. Varwere vanowanzotarisana nekupiswa nezuva pavanotora mishonga iyi uye vanofanirwa kutora matanho sekudzivirira zuva, nhovo, uye sunscreen.
Intracranial hypertension (IH) yakave zvakare ichibatanidzwa nekushandiswa kwetetracyclines senge minocycline uye doxycycline. IH inogona kuunza nemusoro, kusaona chiratidzo, diplopia, uye / kana kurasikirwa kwemaonero. Vakadzi vane zera rekubereka avo vakafuta zvakanyanya vane njodzi yakakwira yeH.
Inowanzo bvunzwa mibvunzo nezve minocycline vs. doxycycline
Chii chinonzi minocycline?
Minocycline inorayirwa tetracycline antibiotic inoshandiswa kazhinji kurapa mamiriro eganda senge acne vulgaris uye acne rosacea, chirwere chekufema, hutachiona hwehutachiona, uye zvimwe zvirwere zvepabonde. Minocycline inowanikwa mumapiritsi uye macapsule mune akasiyana ekukurumidza uye akawedzeredzwa-mafomu ekuburitsa.
Chii chinonzi doxycycline?
Doxycycline inorayirwa tetracycline mishonga inorwisa mabhakitiriya inowanzo shandiswa muacne vulgaris, acne rosacea, hutachiona hwekufema, uye isiri-gonococcal urethritis uye cervicitis. Doxycycline inowanikwa mumapiritsi uye macapsule mune akasiyana ekukurumidza uye akawedzeredzwa-mafomu ekuburitsa.
Minocycline uye doxycycline zvakafanana here?
Minocycline uye doxycycline ese ari maviri tetracycline mishonga inorwisa mabhakitiriya, asi iwo haana kufanana mushonga. Ivo vane zvishoma zvakasiyana mabhakitiriya kufukidza, izvo zvinoita kuti iwo ega abatsire mune mamwe akasarudzika hutachiona.
Minocycline kana doxycycline iri nani here?
Kana uchiongorora varwere vari kurapwa zvakanyanya acne acne rosacea, imwe kliniki yekuongorora yakaratidza kuti minocycline yakabatanidzwa nekuregererwa kwenguva refu kwezviratidzo. Kuongorora kwakasiyana kwemabhuku kunoratidza kuti doxycycline inogona kusangana nezviitiko zvishoma zvakashata pane minocycline. Ose madhiragi aya aratidzwa kuti anoshanda pazviratidzo zvavo zvakagamuchirwa.
Ndinogona here kushandisa minocycline kana doxycycline ndichiine nhumbu?
Minocycline uye doxycycline ane nhumbu chikamu D, zvichireva kuti pane humbowo hwekuti kutora mishonga iyi panguva yekuzvitakura kunogona kukuvadza mwana. Iko kushandiswa kwemishonga iyi mukuzvitakura kunofanirwa kungogumira pakurapa chete mamiriro ekutyisidzira hupenyu ayo pasina imwe sarudzo yakachengeteka.
Ndinogona here kushandisa minocycline kana doxycycline nedoro?
Tetracycline mishonga inorwisa mabhakitiriya yakaita se minocycline uye doxycycline yakabatana nechiropa chepfu. Doro rinoshandisa uchitora mishonga iyi rakaodzwa moyo, kunyanya kune avo varwere vane nhoroondo yekukanganiswa kwechiropa kana hepatitis.
Minocycline mushonga unorwisa mabhakitiriya here?
Minocycline inovhara huwandu hwakawanda hwehutachiona mhando, kusanganisira imwe gramu-isina uye akawanda mabhakitiriya. Iyi yekuvhara inoita kuti ibudirire mune dzakasiyana ganda, weti, kufema, uye zvepabonde.
Sei usingakwanise kurara mushure mekutora minocycline?
Minocycline inogona kukonzera esophageal kutsamwa kana ulceration uye nekudaro inofanirwa kupihwa apo murwere anogona kuramba akamira kweinenge maminetsi makumi matatu kusvika paawa rimwe. Kuisa pasi kunogona kunonoka kufambisa kwemushonga kuburikidza nesophagus uye kuwedzera mukana wekutsamwa kana ulceration.
Ini ndinofanira kutora minocycline mangwanani kana husiku?
Kana murwere achitora minocycline kamwe chete zuva nezuva, zvine hungwaru chirwere ichi chingaitika mangwanani sezvo varwere vangatarisira kuve vakamira kwenguva yakareba vachitevera dhizaini yemangwanani. Kana chinodikanwa chemanheru chichifanira, zvakanakisa kuti muyero wemanheru unopihwa pachine nguva zvakakwana kuti ubvumire murwere kuti ave akatwasuka kwemaminitsi makumi matatu kusvika paawa rimwe asati arara.
