Levalbuterol vs. Albuterol: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Levalbuterol uye albuterol mishonga miviri inoshandiswa pakurapa bronchospasm inoenderana neasthma uye chisingaperi obstructive pulmonary chirwere (COPD). Asthma chirwere chekufema chinobata vanhu veese mazera. Iyo inoratidzirwa nekufema, kukosora, kupfupika kwemweya wekufema, uye chipfuva kuomarara. Inofungidzirwa kuti asima inobata vanhu vangangosvika mamirioni makumi maviri nemana muUnited States, kusanganisira vana mamirioni manomwe.
COPD , dzimwe nguva inonzi emphysema, ine maitiro akafanana neasthma, asi zvakare inosanganisira kugadzirwa kwemakonzo mukobvu mumhepo. Icho chinonyanya kukonzera asthma hachizivikanwe, asi ruzhinji rwevarwere vanokudziridza COPD vane nhoroondo yekuputa kana kwenguva refu kuratidzwa kwemapapu anogumbura.
Bronchospasm inotsanangura maitiro anoitika mune zvese asima neCOPD panobvumirana nendege, zvichiita kuti zviome kupfuudza mweya. Izvi dzimwe nguva zvinonzi bronchoconstriction. Levalbuterol uye albuterol vese vanorapa bronchospasm, asi vanoshanda zvakasiyana.
Ndeupi mutsauko mukuru pakati peLevalbuterol neAluteruter?
Levalbuterol imushonga wepiritsi unosarudzika zvine mutsindo, pfupi-inoshanda beta-2-receptor agonist (SABA). Levalbuterol ndiyo inonyanya kushanda R-enantiomer yemusanganiswa wealbuterol racemic. Levalbuterol inosimudzira iyo beta receptors inounza kuzorora kweye bronchial uye tracheal inotsvedzerera mhasuru uye yakavhurika nzira yemhepo. Levalbuterol inowanikwa se metered-dose inhaler (MDI) inoburitsa 45 mcg dose paactuation. Iyo zvakare inowanikwa semhinduro yekushandisa mune nebulizer muchina. Iyi nebulizer solution inowanikwa mukuwanda kwe 0.31 mg / 3 ml, 0.63 mg / 3 ml, uye 1.25 mg / 3ml.
Albuterol imushonga wenyanzvi uyo zvakare wakasarudzika zvine mutsindo, pfupi-inoshanda beta-2-receptor agonist (SABA). Albuterol musanganiswa werudzi rweR-enantiomers uye S-enantiomers ine R-enantiomer ichiva isomer inoshanda uye chinhu chinoshanda mu levalbuterol. Racemic albuterol inowanikwa mumatafura emuromo musimba rekusununguka-2 mg uye 4 mg uye yakawedzera-kuburitsa 4 mg uye 8 mg. Albuterol inowanikwawo mumhinduro yemuromo musanganiswa ye2 mg / 5 ml. Albuterol inouyawo mune metered-dose inhaler inoburitsa 90 mcg paactuation pamwe nemhando dzakasiyana dzemhinduro dze nebulizer.
| Misiyano mikuru pakati peLevalbuterol neAlbuterol | ||
|---|---|---|
| Levalbuterol | Albuterol | |
| Kirasi yemishonga | Zvine mwero kusarudza pfupi-inoshanda beta-2-agonist | Zvine mwero kusarudza pfupi-inoshanda beta-2-agonist |
| Brand / generic chinzvimbo | Brand uye generic inowanikwa | Brand uye generic inowanikwa |
| Chii chinonzi zita rechiratidzo? | Xopenex | ProAir, Proventil, Ventolin, Accuneb, Vospire |
| Ndeapi mafomu (s) ayo mushonga unouya? | Metered-dose inhaler, nebulizer mhinduro | Metered-dose inhaler, nebulizer solution, mapiritsi emuromo, mhinduro yemumuromo |
| Ndeipi muyero wakajairwa? | 0.63 mg kuburikidza nebulizer kana 45 mcg kuburikidza neMDC maawa ese 4-6 | 2.5 mg kuburikidza nebulizer kana 90 mcg kuburikidza neMDC maawa ese 4-6 |
| Inguva yakareba sei kurapwa kwacho? | Inopindirana, pfupi pfupi | Inopindirana, pfupi-pfupi |
| Ndiani anowanzoshandisa mushonga? | Vana vane makore mana ekuberekwa uye vakuru, vakuru | Vacheche, vana, vakuru |
Mamiriro ezvinhu akarapwa naLevalbuterol uye Albuterol
Levalbuterol uye albuterol ese anoshanda nekusimudzira beta receptors kukonzeresa kutsetseka kwemhasuru mumhepo, zvichidaro kubvumira nzira dzemhepo kuvhura uye kutakura mweya wakawanda kuenda kumapapu nekushomeka kushoma.
Ose maviri levalbuterol uye albuterol ari FDA anotenderwa pakurapa kwekuwedzera kweasthma, bronchospasms inononoka kana kufema, uye bronchospasm inoenderana neCOPD. Izvo zvakakosha kuti uzive kuti hapana mushonga unobvumidzwa seprophylaxis, kana kudzivirira, kune izvi zvinoratidza. Nekudaro, albuterol inogamuchirwa kuti ishandiswe muprophylaxis yekurovedza muviri-inosimudzira bronchospasm. Kazhinji, albuterol yaizopihwa maminetsi gumi neshanu isati yataridzirwa kurovedza muviri kuti ideredze mukana webronchospasm unokonzerwa nekurovedza muviri. Levalbuterol dzimwe nguva inoshandiswa isiri-yechiratidzo chechiratidzo ichi futi. Off-label zvinoreva kuti mushonga hauna kubvumidzwa kuti ushandiswe mune ichi chiratidzo neKudya neDrug Administration (FDA).
Chati inotevera inonyora zvinoshandiswa zvinowanzozivikanwa pamushonga uyu. Chete mupi wako wekuchengetedza hutano ndiye anogona kuona kana aya madhiragi akakodzera mamiriro ako. Mune zviitiko zveakanyanya asthma uye COPD bronchospasm, ndapota tsvaga kurapwa mune iripedyo dhipatimendi rekukurumidzira.
| Mamiriro | Levalbuterol | Albuterol |
| Kuwedzera kwechirwere | Ehe | Ehe |
| Inononoka bronchospasm / episodic kurira | Ehe | Ehe |
| Exercise-inosimudzira bronchospasm prophylaxis | Kunze-chitaridzi | Ehe |
| COPD inosanganisirwa bronchospasm | Ehe | Ehe |
| Kurapa kwakanyanya kwehyperkalemia | Kunze-chitaridzi | Kunze-chitaridzi |
| Inowirirana kurapwa kune neonatal mweya wekufema | Kwete | Kunze-chitaridzi |
Levalbuterol kana Albuterol inoshanda zvakanyanya here?
Levalbuterol uye albuterol zvakafananidzwa zvakanyanya zvine chekuita neasthma neCOPD mhedzisiro. A 2015 kudzidza vakaongorora vanhu vakuru vakaiswa muchipatara vaine asthma kana kuwedzera kweCOPD vaibatwa nelevalbuterol kana albuterol inotungamirwa nebulization. Mhedzisiro yeiyi kiriniki yekuyedza yakawana kuti zvabuda zvemakiriniki zvakange zvakafanana pakati pemishonga iyi miviri uye zvese zvaive zvinobudirira kudzikamisa zviratidzo zvebronchospasm. Nekudaro, mutengo welevalbuterol kurapwa waive wakanyanya kudhura kupfuura mutengo wealbuterol kurapwa, uye varwere veboka levalbuterol vaive nechipatara chakarebesa kupfuura varwere veboka realuteruterol. Kugara kwenguva refu muchipatara kunowedzerawo mutengo wepakati wekupindira.
TO meta-kuongorora uye kuongorora kwakarongeka yemayedzo manomwe akasiyana, anosanganisira varwere vanopfuura chiuru nemazana matanhatu, akaitwa achifananidza levalbuterol nealbuterol muacute asthma. Chidzidzo ichi hachina kuwana musiyano wakakura pakati pemushonga kana uchienzanisa mhedzisiro yemakiriniki senge mweya wekufema, oxygen saturation, uye shanduko muhuwandu hwemapapu. Lung vhoriyamu dzimwe nguva inonzi yakamanikidzwa kufuridzira vhoriyamu, kana FEV1, mune zvekurapa mabhuku. Ichi chidzidzo chakagumisa kuti pakanga pasina humbowo hwekutsigira kusarudza levalbuterol pamusoro pealbuterol mukurapa asthma.
Kunyange madhiragi ese ari maviri achishanda, vanyoreri vanogona kuyera kushayikwa kweuchapupu hwehukuru hwelevalbuterol uye nemutengo wakakwira kana uchisarudza kuti ndeupi mushonga wekupa. Levalbuterol inogamuchirwa chete muvarwere vevana makore mana zvichikwira, saka albuterol inogona kusarudzika muvechidiki vana vehuwandu. Chiremba wako chete ndiye anogona kusarudza chaiyo mishonga yemamiriro ako.
Tora mushonga unonyorwa
Kuvhavha uye mutengo kuenzanisa kweLevalbuterol vs. Albuterol
Levalbuterol imishonga yemishonga inowanzo kuvharwa nezvirongwa zveinishuwarenzi zvekutengesa. Inogona kuvharwa neiyo Medicare Chikamu D kana Chikamu B chirongwa zvichienderana nekutariswa. Pasina kufukidzwa, levalbuterol inogona kukubhadhara zvinodarika $ 170. YegaConcon coupon ye generic Levalbuterol inogona kudzikisa mutengo kusvika kumadhora makumi matatu kuma Pharmacies ari kutora chikamu.
Albuterol inogona kuvharwa neiyo Medicare Chikamu D kana Chikamu B chirongwa zvichienderana nekutariswa. Iyo zvakare inowanzo kuvharwa nezvirongwa zvekushambadzira zveinishuwarenzi. Albuterol inogona kuita madhora makumi mana pasina kufukidzwa, asi nekoponi kubva kuSingleCare, unogona kuwana fomu generic isingasviki madhora gumi kuma Pharmacies ari kutora chikamu.
| Levalbuterol | Albuterol | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Zvinoenderana nekuongororwa | Zvinoenderana nekuongororwa |
| Standard muyero | 25, 0.63 mg / 3 ml | 25, 2.5 mg / 3 ml |
| Chaizvoizvo Medicare copay | Zvinoenderana nechirongwa | Zvinoenderana nechirongwa |
| SingleCare mutengo | $ 30- $ 130 | $ 10- $ 20 |
Zvakajairika mhedzisiro mhedzisiro yeLevalbuterol vs. Albuterol
Nepo levalbuterol uye albuterol vari pakati nepakati kusarudza mabeta receptors pane yakatsetseka tsandanyama yemweya nzira, panogona kunge paine imwe yemoyo beta-receptor kukurudzira ichikonzera kuwedzera kweiyo yemoyo, inozivikanwa se tachycardia. Ose maviri levalbuterol uye albuterol anogona kukonzera kutya uye kudedera. Migraine uye dzungu rakaonekwa nelevalbuterol, asi kwete albuterol.
Izvi hazviitirwe kuti zvive zvakazara rondedzero yezvingaitika zvakashata mhedzisiro. Ndokumbirawo ubvunze wako mupi wezvehutano nezve runyorwa ruzere rwe madambudziko.
| Levalbuterol | Albuterol | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Tachycardia | Ehe | 2.7% | Ehe | 2.7% |
| Migraine | Ehe | 2.7% | Kwete | n / a |
| Dyspepsia | Ehe | 2.7% | Ehe | 1.4% |
| Makumbo emakumbo | Ehe | 2.7% | Ehe | 1.4% |
| Dzungu | Ehe | 2.7% | Kwete | n / a |
| Hypertension | Kwete | n / a | Ehe | 2.7% |
| Kutya | Ehe | 9.6% | Ehe | 8.1% |
| Kudedera | Ehe | 6.8% | Ehe | 2.7% |
| Kufunganya | Ehe | 2.7% | Kwete | n / a |
| Kuwedzera kukosora | Ehe | 4.1% | Ehe | 2.7% |
| Utachiona hwehutachiona | Ehe | 12.3% | Ehe | 12.2% |
| Rhinitis | Ehe | 2.7% | Ehe | 6.8% |
| Sinusitis | Ehe | 1.4% | Ehe | 2.4% |
| Turbinate edema | Ehe | 1.4% | Kwete | n / a |
Kwayaka: Levalbuterol ( Zuva Nezuva Albuterol ( Zuva Nezuva )
Kudyidzana kwemishonga yeLevalbuterol vs. Albuterol
Nekuda kwekufanana kwavo kwemakemikari, mukana wekupindirana kwezvinodhaka welevalbuterol uye albuterol zvakafanana. Azithromycin, inorwisa mabhakitiriya yakajairika inoshandiswa muzvirwere zvepamusoro zvekufema, inofanirwa kudzivirirwa pamwe chete nelevalbuterol kana albuterol pazvinogoneka. Azithromycin, kana ichitungamirwa neyepfupi-inoshanda beta-agonists, ine njodzi yakawedzera yekukonzeresa kuwedzera kweQT, rudzi rwemoyo arrhythmia. Kana musanganiswa uyu uchifanira kushandiswa, basa remwoyo wemurwere rinofanira kutariswa zvakanyanya. Izvo zvakakosha kuti uwane hwaro hwekutanga hwemoyo basa usati waisa aya madhiragi panguva imwe chete.
Beta blockers, inowanzo shandiswa kudzora kurova kwemoyo uye kuwedzerwa kweropa, zvinoshanda zvakapesana neBeta-agonists. Mabasa avo anozopesana. Kana murwere achifanira kuve ari maviri beta blocker uye beta-agonist, uchishandisa cardioselective beta blocker inosarudzwa. Mienzaniso ye cardioselective beta blockers inosanganisira atenolol uye metoprolol, pakati pevamwe.
Iri harisi runyorwa rwakakwana rwekupindirana kwezvinodhaka. Ndokumbirawo utsvage zano rezvehutano renyanzvi yezvehutano kuti unzwisise zvizere nezvekugona kudyidzana kwezvinodhaka.
| Zvinodhaka | Kirasi yemishonga | Levalbuterol | Albuterol |
| Caffeine | Xanthine yakabva / CNS inosimudzira | Ehe | Ehe |
| Phenylephrine Pseudoephedrine | Vanodzikisira | Ehe | Ehe |
| Acebutolol Atenolol Betaxolol Bisoprolol Carvedilol Metoprolol Nadolol Nebivolol Propranolol Sotalol | Beta blockers (beta vanopikisa) | Ehe | Ehe |
| Amiodarone Dronedarone | Anti-arrhythmics | Ehe | Ehe |
| Amitriptyline Clomipramine Nortriptyline | Tricyclic antidepressants | Ehe | Ehe |
| Citalopram Escitalopram Fluoxetine Sertraline | Kusarudza serotonin reuptake inhibitors (SSRIs) | Ehe | Ehe |
| Azithromycin Clarithromycin | Mishonga inorwisa mabhakitiriya | Ehe | Ehe |
| Fluconazole Itraconazole Ketoconazole | Antifungals | Ehe | Ehe |
Yambiro yeLevalbuterol uye Albuterol
Levalbuterol uye albuterol zvinogona kukonzera paradoxical bronchospasm, mamiriro apo bronchospasm yemurwere kana vhiri rinotonyanya kuwedzera pane kugadzirisa. Kana izvi zvikaitika, kurapwa kunofanirwa kumiswa nekukasika uye kurapwa kutsva kunofanira kutanga.
Kugadziriswa kweasima kunogona kuitika kwenguva yakareba, mazuva, kana kupfuura. Kana murwere weasthmatic akatanga kuda kuwedzera huwandu hwebronchodilator kudzora zviratidzo zveasima, ichi chingave chiratidzo chekuti kugadzikana kuri kuitika. Varwere vanoona izvi vangangoda anti-anogumbura marapirwo senge corticosteroids kana shanduko mune yavo yekuchengetedza mishonga regimen.
Levalbuterol uye albuterol, kunyanya pamadosi ari pamusoro pehuwandu hwakakurudzirwa, inogona kukonzera zvakakomba zvemoyo mhedzisiro sekuwedzera kwemoyo uye BP. Mune zvimwe zviitiko zvakakomba, kusungwa kwemoyo kwakaitika. Usambofa wakapfuudza iyo yakakurudzirwa dosing yako yakarairwa nachiremba wako.
Low serum potassium mazinga, kana hypokalemia, yakaonekwa nelevalbuterol uye albuterol. Izvi zvinogona kukonzerwa neyakavanzika masisitimu shunting. Nepo mishonga iyi dzimwe nguva ichishandiswa-kuregedzwa kudzikisa potasiamu nemaune, mhedzisiro iyi inofanira kuongororwa.
Inowanzo bvunzwa mibvunzo nezve Levalbuterol vs. Albuterol
Chii chinonzi Levalbuterol?
Levalbuterol imushonga wepiritsi iyo iri pfupi-inoshanda beta-agonist, inozivikanwawo seye bronchodilator. Inoshandiswa kurapa bronchospasm inoenderana neasthma neCOPD. Inoshandiswa zvakare off-label kubatsira kudzivirira kurovedza muviri-kunokonzerwa bronchospasm. Inowanikwa muchimiro chemeredhi-inhaler inhaler pamwe nemhinduro dzekushandisa mune nebulizer.
Chii chinonzi Albuterol?
Albuterol zvakare inonyorwa mushonga iyo iri pfupi-inoshanda beta-agonist. Iyo inozivikanwa zvakare seye bronchodilator uye inoshandiswa kurapa bronchospasm inoenderana neasthma neCOPD pamwe nekudzivirira kurovedza muviri-kunokonzerwa bronchospasm. Inowanikwa nenzira dzakasiyana siyana dzinosanganisira mapiritsi emuromo, mhinduro dzemumuromo, metered-dose inhalers, uye mhinduro dzinoshandiswa mune nebulizer.
Levalbuterol neAluterol zvakafanana here?
Levalbuterol uye albuterol zvakafanana nemakemikari, asi hazvina kunyatsofanana. Albuterol musanganiswa werusaruro wemakemikari enantiomers maviri, R-albuterol uye S-albuterol. Iyo dzimwe nguva inonzi seacademic albuterol. Levalbuterol inoumbwa neR-albuterol chete, inonyanya kushanda yemakomponi maviri.
Levalbuterol kana Albuterol iri nani here?
Kudzokororazve kuenzanisa zvidzidzo Yakazara yakaratidza kuti levalbuterol uye albuterol vane zvakafanana kiriniki mhedzisiro. Vamiriri vanogona kufunga nezvehunhu hwakadai mutengo uye zvinogona kukonzeresa mhedzisiro pavanosarudza imwe pamusoro peimwe.
Ndinogona here kushandisa Levalbuterol kana Albuterol ndichiri nepamuviri?
Levalbuterol uye albuterol ese ari maviri anoonekwa sepamuviri nharaunda C neCDA. Izvi zvinoreva kuti hapana zvakanaka zvekiriniki zvidzidzo kuratidza kuchengetedzeka pakubata. Iyi mishonga inofanirwa kungoshandiswa chete kana mabhenefiti akanyatso kuwanda panjodzi. Mune zviitiko izvi, albuterol inogona kusarudzika nekuda kwekuvapo kweimwe dhata yezvakaitika pakushandiswa kwayo mukuzvitakura.
Ndinogona here kushandisa Levalbuterol kana Albuterol nedoro?
Iko hakuna zvakananga zvinopesana nealbuterol uye doro. Nekudaro, doro rinogona kunonoka kufema uye kukanganisa mapapu, izvo zvinopesana nekurapa bronchospasm.
Is Levalbuterol kununura inhaler?
Ehe, levalbuterol HFA inunura inhaler inoratidzwa kuti ishandiswe pakurapa kweacute asthma kuwedzera kana bronchospasms nekuda kweCOPD.
Levalbuterol iri steroid?
Levalbuterol haisi steroid kana inopesana nekuzvimba uye haifanire kushandiswa panzvimbo yesteroid kana kushandiswa kwesteroin kuchiratidzwa, senge mukushaya mweya kwechirwere.
Inotora nguva yakareba sei Levalbuterol?
Paavhareji, mhedzisiro yedhizaini imwe yealevalbuterol inogona kutora maawa mashanu kusvika matanhatu. Levalbuterol inotanga kushanda maminetsi gumi nemashanu mushure mekutungamira.
