Incruse Ellipta vs. Spiriva: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Zvinoenderana ne American Lung Association , chisingaperi obstructive pulmonary chirwere, kana COPD, ndiyo yechitatu inotungamira kukonzera rufu nezvirwere muU.S. Vanopfuura mamirioni gumi nematanhatu vanhu vakaonekwa vaine COPD, nemamirioni angangove akabatwa asi asiri kuziva. COPD chirwere chisingaperi chinoputira mapapu. Varwere vane COPD vanowanzoona kunetseka kufema, kukosora, kufema, uye kugadzirwa kwemashure. COPD inosanganisira emphysema uye chisingaperi bronchitis. Mishonga miviri yakajairika inoshandiswa kubata COPD mishonga yemumuromo inhaled inonzi Incruse Ellipta naSpiriva.
Incruse Ellipta naSpiriva ese ari maviri mazita ezita remishonga anoratidzwa ekurapa kwenguva refu kurapwa kwe COPD . Mishonga iyi miviri inogamuchirwa neU.S.Food and Drug Administration (FDA). Ivo vanoiswa muboka remishonga inonzi anticholinergics. Ivo vanoshanda nekuzorodza mhasuru mumapapu, zvichiita kuti kufema kuve nyore.
Kunyangwe Incruse Ellipta uye Spiriva ari maviri anticholinergics anoshandiswa kuCOPD, iwo haana kunyatso kufanana. Enderera kuverenga pazasi kuti udzidze zvakawanda nezveumwe mushonga.
Ndeupi mutsauko mukuru pakati peIncruse Ellipta naSpiriva?
Incruse Ellipta uye Spiriva ese ari maviri anticholinergic mishonga, inowanikwa muzita rezita chete. Ivo vanozivikanwa zvakare sevanoshanda kwenguva refu muscarinic vanopikisa (LAMA).
Iyo kemikari zita reIncruse Ellipta is umeclidinium. Inowanikwa mune inhaler fomu chete. GlaxoSmithKline (GSK) inogadzira Incruse Ellipta.
Iyo kemikari zita reSpiriva ndeye tiotropium bromide. Inowanikwa seyemumuromo kapulepisi (yemumuromo inhalation, isingamedzwe- inonziwo poda yakaoma inhaler) uye nemuromo inhalation mhute. Boehringer Ingelheim Pharmaceuticals inogadzira Spiriva.
| Misiyano mikuru pakati peIncruse Ellipta naSpiriva | ||
|---|---|---|
| Incruse Ellipta | Spiriva | |
| Kirasi yemishonga | Anticholinergic | Anticholinergic |
| Brand / generic chinzvimbo | Brand | Brand |
| Chii chinonzi generic zita? | Umeclidinium | Tiotropium bromide |
| Ndeapi mafomu (s) ayo mushonga unouya? | Incruse Ellipta Inhaler (inhalation poda) | Spiriva Handihaler (capsules for inhalation), Spiriva Respimat (inhalation mhute) |
| Ndeipi muyero wakajairwa? | Imwe inhalation inhalation (62.5 mcg) kamwe zuva nezuva panguva imwechete mazuva ese | Spiriva Handihaler: Maviri emumuromo inhalations yehupfu zvirimo mune imwe Spiriva capsule (18 mcg) kamwe pazuva, neiyo Handihaler chishandiso (macapsuleti ndeemumuromo inhalation chete; kwete kumedzwa) Spiriva Respimat: 2 yemumuromo inhalations (ye1.25 mcg kana 2.5 mcg) kamwe pazuva |
| Yakareba sei iyo yekurapa? | Nguva refu | Nguva refu |
| Ndiani anowanzoshandisa mushonga? | Vakuru | Handihaler: Vakuru Respimat: Vakuru nevana makore matanhatu zvichikwira |
Mamiriro ezvinhu akarapwa naIncruse Ellipta naSpiriva
Incruse Ellipta uye Spiriva zvinoratidzirwa pakurapa kwekurapa kwechirwere chisingaperi chisingabvumirwe chemapapu (COPD). Kunyanya zvakanyanya, iyo Spiriva Handihaler yekugadzira ruzivo inonyora kuti inoshandiswa kudzikisira kuwedzera kwevarwere veCOPD.
Spiriva Respimat ine chimwezve chiratidzo - kurapwa kwekurapa kweasima muvarwere vane makore matanhatu zvichikwira.
Hapana mushonga unofanirwa kushandiswa pakurwisa kwakanyanya.
| Mamiriro | Incruse Ellipta | Spiriva |
| Kuchengetedza kurapwa kweCOPD | Ehe | Hongu (Handihaler uye Respimat) |
| Kuchengetedza kurapwa kweasthma muvarwere makore matanhatu zvichikwira | Kwete | Hongu (Respimat) |
Incruse Ellipta kana Spiriva inoshanda here?
Iko kune mashoma data achienzanisa iyo miviri mishonga zvakananga. A 12-vhiki kudzidza yakafananidza kushanda pamwe nekuchengeteka kweIncruse Ellipta uye Spiriva mune vangangopfuura chiuru chevarwere vane COPD. Iyo yekupedzisira yekupedzisira yaive yekumanikidza yakamanikidzwa kufema vhoriyamu mune imwe sekondi (inonziwo FEV1) pazuva 85. Varwere vakaongororwa vachishandisa St George's Respiratory Questionnaire uye kumwe kuongorora. Ose madhiragi airatidza kunatsiridza zvine mutsindo muhupenyu hwehupenyu uye ainyatsoshivirirwa maererano nekuchengetedza. Chidzidzo chacho chakagumisa Incruse Ellipta kuti ibudirire kupfuura Spiriva.
Chete mupi wako wekuchengetedza hutano ndiye anogona kuona yakanyanya inoshanda mishonga kwauri. Iye kana iye anogona kutarisa kuomarara kwezviratidzo zvako uye nhoroondo yako yekurapa, pamwe chete nemimwe mishonga yaunotora iyo inogona kusangana neIncruse Ellipta kana Spiriva.
Kuvhavha uye mutengo kuenzanisa kweIncruse Ellipta vs. Spiriva
Inishuwarenzi inoronga uye Medicare Chikamu D inovhara zvese Incruse Ellipta uye Spiriva, asi huwandu hwekuvhara hunosiyana nechirongwa.
Mutengo wekunze kwehomwe weIncruse Ellipta inhaler unosvika madhora mazana mana nemakumi manomwe nemanomwe, asi unogona kushandisa kadhi reSingleCare kudzikisa mutengo kusvika pamadhora mazana matatu nemakumi matanhatu.
Mutengo wekunze kwehomwe weSpiriva Handihaler unosvika madhora mazana matanhatu nemakumi matanhatu nemana, uye Spiriva Respimat inenge madhora mazana matanhatu. Kushandisa CouponCare koponi kunodzikisa mutengo kusvika pamadhora mazana mana nemakumi mana mana eHandihaler kana iyo Respimat.
| Incruse Ellipta | Spiriva | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 1 inhaler | 1 Handihaler kana 1 Respimat |
| Chaizvoizvo Medicare copay | $ 8- $ 395 | $ 3- $ 524 |
| SingleCare mutengo | $ 306 + | $ 404 + |
Zvakajairika mhedzisiro mhedzisiro yeIncruse Ellipta vs. Spiriva
Mhedzisiro inowanzoitika yeIncruse Ellipta ndeye nasopharyngitis (yakajairika kutonhora), yepamusoro yekufema chirwere chetachiona, uye kukosora.
Spiriva inowanzoitika mhedzisiro hutachiona hwepamusoro hwekufema, sinusitis, kurwadziwa pachipfuva, mukanwa wakaoma, kuzvimbirwa, uye hutachiona hwehutachiona.
Iri harisi rondedzero izere yemhedzisiro. Mimwe mhedzisiro yakaipa inogona kuitika. Bata wako mupi wezvehutano kuti uwane izere runyorwa rwemhedzisiro mhedzisiro yeIncruse Ellipta uye Spiriva.
| Incruse Ellipta | Spiriva | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Nasopharyngitis / pharyngitis | Ehe | 8% | Ehe | 9% |
| Utachiona hwepamusoro hwekufema | Ehe | 5% | Ehe | 41% |
| Kukosora | Ehe | 3% | Ehe | > 3% |
| Kurwadziwa pachifuva | Kwete | - | Ehe | 7% |
| Muromo wakaoma | Kwete | - | Ehe | 16% |
| Kuzvimbirwa | Kwete | - | Ehe | 4% |
| Kusvipa | Kwete | - | Ehe | 4% |
| Sinusitis | Ehe | Hazvina kutaurwa | Ehe | gumi neimwe% |
| Mapundu | Ehe | Hazvina kutaurwa | Ehe | 4% |
| Arthralgia (kurwadziwa pamwe chete) | Ehe | piri% | Ehe | 4.2% |
| Urinary turakiti hutachiona | Ehe | Hazvina kutaurwa | Ehe | 7% |
Kwayaka: DailyMed ( Incruse Ellipta ), Zuva Nezuva ( Spiriva )
Kubatana kwezvinodhaka kweIncruse Ellipta vs. Spiriva
Nekuti Incruse Ellipta uye Spiriva mishonga yeanticholinergic, haifanire kushandiswa nemimwe mishonga yeanticholinergic. Iko kusanganisa kunogona kukonzera kuwedzera kwemhedzisiro, sekuchengeta weti kana yakatetepa-kona glaucoma.
Kumwe kudyidzana kwezvinodhaka kunogona kuitika. Bvunza wako mupi wezvehutano kuti uwane yakazara runyorwa rwekudyidzana zvinodhaka.
| Zvinodhaka | Kirasi yemishonga | Incruse Ellipta | Spiriva |
| Belladonna alkaloids Benztropine Clidinium Darifenacin Dicyclomine Diphenhydramine Hyoscyamine Ipratropium Orphenadrine Oxybutynin Scopolamine Solifenacin Tolterodine Trihexyphenidyl | Anticholinergics | Ehe | Ehe |
Yambiro dzeIncruse Ellipta naSpiriva
- Usashandise Incruse Ellipta kana Spiriva kana iwe uine hypersensitivity yakasimba kumukaka mapuroteni kana chero chipi zvacho chemidziyo.
- Incruse Ellipta kana Spiriva haina kuitirwa kuti ishandiswe mukudzikira nekukurumidza kana kuti inogona kutyisidzira hupenyu COPD episodes yakaoma. Iyi mishonga haisati yadzidzwa muzvikamu zvakanyanya uye haifanirwe kushandiswa kudzikisira zviratidzo zvakakomba. Usatore mimwe mibairo yekusunungurwa kwezviratidzo zvakanyanya. Mubatsiri wako wezvehutano anofanira kukupa rairo pamusoro pekutarisira chiitiko chakakomba - ungangoshandisa imwe, inhaler ipfupi-kuita sekununura inhaler.
- Incruse Ellipta kana Spiriva inogona kukonzeresa kutyisidzira hupenyu kushamisa bronchospasm (kuwedzera kufema kana kufema), iyo inofanirwa kurapwa nekukasira-kuita bronchodilator inhaler. Kana izvi zvikaitika, rega Incruse Ellipta kana Spiriva nekukasira. Mubatsiri wako wehutano anogona kupa imwe nzira yekurapa.
- Incruse Ellipta kana Spiriva inogona kukonzera hypersensitivity reaction, kusanganisira anaphylaxis, angioedema, kuchenesa, kana kukurumidza. Regedza Incruse Ellipta kana Spiriva uye bata wako wezvehutano mupi kana chero chezviitiko izvi zvikaitika. Kana iwe uchinetseka kufema kana kusangana nekuzvimba kwakatenderedza miromo yako, rurimi, uye muromo, tsvaga kurapwa kwekukurumidza.
- Shandisa Incruse Ellipta kana Spiriva nekuchenjerera kune varwere vane rakatetepa-angle glaucoma. Varwere uye avo vanoraira vanofanirwa kutsvaga zviratidzo zveacute yakamanikana-angle glaucoma (kurwadziwa kweziso, kuona kwakashata, kuona halos). Tsvaga wako mupi wezvehutano nekukurumidza kana chimwe chezviratidzo izvi chikaitika.
- Shandisa Incruse Ellipta kana Spiriva nekuchenjerera kune varwere vane weti yekuchengetedza. Varwere uye vanyoreri vanofanirwa kuziva zviratidzo zvekuchengeta weti, sekurwadziwa kuita weti uye kunetseka kuita weti. Bvunza wako mupi wezvehutano nekukurumidza kana iwe ukawana izvi zviratidzo.
Spiriva chete:
- Tarisa varwere vane mwero kusvika kwakanyanya kukanganiswa kweitsvo kweanticholinergic mhedzisiro.
- Macapsule ndeemumuromo inhalation chete uye haafanire kumedzwa. Shandisa macapsule chete neiyo Handihaler chishandiso.
Inowanzo bvunzwa mibvunzo nezve Incruse Ellipta vs. Spiriva
Chii chinonzi Incruse Ellipta?
Incruse Ellipta mushonga weanticholinergic unoshandiswa kuCOPD. Inobatsira kusunungura mapapu, zvichiita kuti kufema kuve nyore.
Chii chinonzi Spiriva?
Spiriva zvakare iri anticholinergic mishonga inoshandiswa kuCOPD. Inowanikwa seyakafemereka kapisi uye zvakare seyakafemesa mhute.
Incruse Ellipta naSpiriva vakafanana here?
Ose ari maviri mishonga akafanana uye muchikamu chimwe chete chemishonga. Nekudaro, ivo vane misiyano, senge mhedzisiro uye muyero, yakadomwa pamusoro.
Incruse Ellipta kana Spiriva zvirinani here?
Yakatemwa data iripo ichienzanisa Incruse Ellipta kuna Spiriva. Imwe ongororo yakaratidza Incruse Ellipta kuti ibudirire, asi mishonga yese iri miviri yakachengeteka. Mubatsiri wako wehutano anogona kuona kuti ndeupi mushonga uri nani kwauri.
Ndinogona here kushandisa Incruse Ellipta kana Spiriva ndichiri nepamuviri?
Iko hakuna kukwana ruzivo pamusoro pemhedzisiro yeIncruse Ellipta kana Spiriva mukuzvitakura. Bvunza OB-GYN yako kuti uwane mazano ekurapa. Kana iwe uri kutotora Incruse Ellipta kana Spiriva uye uone kuti iwe une nhumbu, bvunza OB-GYN yako.
Ndinogona here kushandisa Incruse Ellipta kana Spiriva nedoro?
Kunyangwe Incruse Ellipta kana Spiriva isingadyidzane nedoro, kunwa doro kwenguva yakareba kunogona kuwedzera zviratidzo zveCOPD uye kunetesa immune system yako, zvichiwedzera zviratidzo zvako zveCOPD. Bvunza wako mupi wezvehutano kuti uwane rumwe ruzivo nezve doro neCOPD.
Incruse Ellipta isteroid here?
Kwete Incruse Ellipta haisi steroid. Inotorwa semushonga weanticholinergic. Iyo inodzoreredza mhasuru dziri mumhepo nzira kuti kufema kuve nyore.
Mimwe inhalers ine inhaled corticosteroid uye inoshandiswa kurapa COPD. Advair ine fluticasone (steroid) uye salmeterol (yakareba-inoshanda beta-agonist). Mumwe muenzaniso ndeyeBreo Ellipta, iyo ine fluticasone furoate (steroid) uye vilanterol (yakareba-inoshanda beta-agonist).
Ndeipi inhaler yakaenzana nespiriva?
Mimwe inhalers mune imwechete chikamu cheSpiriva uye Incruse Ellipta inosanganisira Tudorza Pressair (aclidinium) uye Seebri Neohaler (glycopyrrolate).
Ndeipi yakanyanya inhaler yeCOPD?
Ndiwo mubvunzo wakaoma. Zvinoenderana nezvinhu zvishoma, senge kuomarara uye mhando yezviratidzo, nhoroondo yako yekurapa, uye mimwe mishonga yaunotora. Mutapi wako wezvehutano anogona kuona kuti ndeipi inhaler yakakunakira iwe.
Kune akawanda emishonga inhaled pamusika. Heano mashoma anowanzo kurayirwa inhaled kurapwa kweCOPD:
SABA (pfupi-inoshanda bronchodilators, kana pfupi-inoshanda beta-agonists): Albuterol HFA, Proair HFA, Proventil HFA, Ventolin HFA, Xopenex
LABAs (yakareba-inoshanda beta2 agonists): Brovana (arformoterol), Serevent (salmeterol)
LAMAs (marefu-anoita muscarinic vanopikisa): Incruse Ellipta (umeclidinium), Seebri (glycopyrrolate), Spiriva (tiotropium) Respimat kana Handihaler, Tudorza Pressair (aclidinium)
LAMA + LABA mubatanidzwa inhaler: Anoro Ellipta (umeclidinium / vilanterol), Bevespi Aerosphere (glycopyrrolate / formoterol), Stiolto Respimat (olodaterol / tiotropium),
Utibron Neohaler (indacaterol / glycopyrrolate)
Inhaled corticosteroids: Qvar RediHaler (beclomethasone), Pulmicort Flexhaler (budesonide)
Kusanganiswa corticosteroid + LABA: Symbicort (budesonide / formoterol), Advair (fluticasone / salmeterol), Breo (fluticasone / vilanterol), Dulera (mometasone / formoterol)
