Etodolac vs. ibuprofen: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Hapana munhu anoda kurarama nekusagadzikana kana kurwadziwa kwenguva yakareba, kana zvachose nekuda kwechinhu ichocho. Neraki, mushonga uye pamusoro-pe-counter marwadzo ekudzora anowanikwa kune yako padyo chitoro chemishonga. Kunyange zvazvo vasina kusimba sekurwadziwa kweopioid, iyo inoda kuongororwa kwakadzama kwekurapa uye kunyorerwa, maNSAID akaita etodolac kana ibuprofen anoshanda pakurapa kurwadziwa kwakapfava kusvika pakati nepakati.
Zvikasadaro inozivikanwa seye nonsteroidal anti-anogumbura zvinodhaka, NSAIDs dzinoshanda nekudzivirira kugadzirwa kweprostaglandin. Muviri wako unogona kupindura kune mamwe marapirwo ekuburitsa prostaglandin, anova makemikari anokonzera kurwadziwa, kuzvimba, uye fivhiri. NSAIDs dzinovhara maprostaglandin-anogadzira enzyme-COX-1 uye COX-2-kudzora kupindirana kwemuviri uye kuderedza marwadzo.
Etodolac uye ibuprofen vanoiswa seNSAIDs. Nekudaro, ivo vane misiyano yakakosha.
Ndeupi mutsauko mukuru pakati peEtodolac uye ibuprofen?
Etodolac dzimwe nguva inozivikanwa neayo (ikozvino yagumiswa) zita rezita, Lodine. Inowanikwa seyakajairika mushonga uye inogona kungowanikwa chete nachiremba wechiremba.
Etodolac ine hafu-yehupenyu hweanosvika maawa matanhatu kusvika manomwe uye inosvika pakakwirira kukwirisa muropa imwe kana maawa maviri mushure mekuimedza. Inowanzo kutorwa kaviri kana katatu zuva nezuva nekuda kwekurwadziwa kubva kuArthritis. Iko kune zvakare etodolac yakawedzerwa-kuburitsa piritsi ine iyo yakareba hafu yehupenyu hweanosvika maawa masere uye inogona kutorwa kamwe zuva nezuva.
Ibuprofen ndiyo yakajairika NSAID iyo inowanikwa pamusoro peiyo-the-counter (OTC). Simba repamusoro reibuprofen rinowanikwawo nemushonga wechiremba. Mazita emazita anozivikanwa ebuprofen anosanganisira Advil, Motrin, uye Midol.
Ibuprofen inosvika pakakwirira muropa mukati meawa imwe kana maviri mushure mekutora. Nekudaro, kusiyana etodolac, ibuprofen ine ipfupi hafu-hupenyu hwekutenderera maawa maviri . Prescription-simba ibuprofen inouya muhwendefa iyo inowanzo kutorwa katatu kana kana zuva nezuva. Iyo OTC vhezheni inouya mumapiritsi emuromo, makapisi, uye kumiswa kwemvura.
| Misiyano mikuru pakati peetodolac uye ibuprofen | ||
|---|---|---|
| Etodolac | Ibuprofen | |
| Kirasi yemishonga | Nonsteroidal anti-anogumbura zvinodhaka (NSAID) | Nonsteroidal anti-anogumbura zvinodhaka (NSAID) |
| Brand / generic chinzvimbo | Generic inowanikwa (brand yakamiswa) | Brand uye generic inowanikwa |
| Chii chinonzi zita rechiratidzo? | Lodine | Advil, Motrin, Midol |
| Ndeapi mafomu (s) ayo mushonga unouya? | Oral capsules Hwendefa remuromo Oral piritsi, yakawedzerwa-kusunungurwa | Oral capsules Hwendefa remuromo Mvura yemumuromo Jekiseni (NeoProfen) |
| Ndeipi muyero wakajairwa? | Zvekurwadziwa: 200 kusvika 400 mg maawa matanhatu kusvika masere ese pazvinodiwa. Usapfuure yakakwira dhosi ye1200 mg pazuva. Kune osteoarthritis kana rheumatoid arthritis: Kuburitsa nekukurumidza 300 mg kaviri kana katatu pazuva kana 400 kusvika 500 mg kaviri pazuva. Yakawedzerwa-kuburitswa 400 kusvika 1000 mg kamwe pazuva. Usapfuure yakakwira dhosi ye1200 mg pazuva. | Kwemarwadzo: 200 kusvika 400 mg maawa mana kusvika matanhatu sezvaanodiwa. Usapfuure yakakwira dhosi ye1200 mg pazuva kana kunze kwekunge waudzwa nachiremba. Kune osteoarthritis kana rheumatoid arthritis: 400 kusvika 800 mg katatu kana kana zuva nezuva. Usapfuure yakakwira dosi ye3200 mg pazuva. |
| Inguva yakareba sei kurapwa kwacho? | Nguva yekurapa inoenderana nehutano mamiriro, kuomarara kwekutambudzika, uye zvimwe zvinhu. Kurapa kunogona kunge kuri kwenguva pfupi kana kwenguva refu. | Nguva yekurapa inoenderana nehutano mamiriro, kuomarara kwekutambudzika, uye zvimwe zvinhu. Kurapa kunogona kunge kuri kwenguva pfupi kana kwenguva refu. |
| Ndiani anowanzoshandisa mushonga? | Vakuru nevana makore matanhatu zvichikwira | Vakuru nevana 6 months zvichikwira |
Mamiriro ezvinhu anorapwa etodolac uye ibuprofen
Etodolac uye ibuprofen zvakanyorwa kurapa kurwadziwa. Ivo anowanzo kutorwa kurapa hunyoro kusvika pakati nepakati kurwadziwa kwakanyanya kubva kumazino maitiro, migraines , kana tsandanyama aches (myalgia).
Etodolac uye ibuprofen zvinonyanya kubatsira uye FDA inogamuchirwa yekurapa kurwadziwa uye kuzvimba kubva kuosteoarthritis uye rheumatoid arthritis. Simba repamusoro rinowanzo fanirwa kugadzirisa kurwadziwa kwakanyanya kwemajoini kana kurwadziwa kwepfupa kwakabatana neArthritis. Mune zvimwe zviitiko, vana vari pamusoro peyakaganhurirwa zera muganho vanogona zvakare kurapwa neaya maNSAID e vechidiki idiopathic arthritis .
Over-the-counter ibuprofen yakanyorwa kurapa fivha uye kumwedzi kurwadza (primary dysmenorrhea). Iyo jekiseni fomu yeibuprofen inonzi NeoProfen inoshandiswa kurapa patent ductus arteriosus (PDA), rudzi rwehurema hwemwoyo, muvacheche vasati vazvarwa.
| Mamiriro | Etodolac | Ibuprofen |
| Kurwadziwa | Ehe | Ehe |
| Osteoarthritis | Ehe | Ehe |
| Rheumatoid arthritis | Ehe | Ehe |
| Wechidiki idiopathic arthritis | Ehe | Ehe |
| Kupindwa nechando | Kwete | Ehe |
| Yakanyanya dysmenorrhea | Kwete | Ehe |
| Patent ductus arteriosus | Kwete | Ehe |
Etodolac kana ibuprofen inoshanda zvakanyanya here?
Ose etodolac uye ibuprofen anoshanda maNSAID ekurwadziwa kwekurwadziwa. Ivo vaviri anovhara cyclooxygenase (COX) enzymes kudzora kuzvimba uye kuderedza marwadzo kune avo vane arthritis. Nekudaro, mhedzisiro yeetodolac inogara kwenguva yakati rebei. Naizvozvo, vamwe vanhu vanogona kusarudza etodolac yeiyo yepazasi-frequency dosing.
Muchidzidzo chebofu-bofu kuenzanisa etodolac uye ibuprofen , 1,446 varwere vane rheumatoid arthritis vakapihwa 150 mg etodolac kaviri pazuva, 500 mg etodolac kaviri pazuva, kana 600 mg yebuprofen kanomwe pazuva. Ose madhiri eetodolac akawanikwa akafanana mukushanda kune iyo ibuprofen dosage. Panyaya yemhedzisiro, avo vanotora etodolac vakasangana nekuzvimbirwa kushoma, kuputika, uye kubuda ropa mudumbu pane avo vanotora ibuprofen. Zvisinei, izvi zvinogona kunge zvine chekuita nemari yevarwere vezvinodhaka vakapihwa.
Kunyange pasina mimwe miedzo yemakiriniki yakafananidza zvakananga etodolac uye ibuprofen, zvidzidzo zvakasiyana zvakafananidza dzimwe NSAID kune etodolac kana ibuprofen. Imwe meta-ongororo yakawana kuti iyo huwandu hwezuva nezuva diclofenac inoshanda zvakanyanya kupfuura yakanyanya mazuva ese madhayeti ebuprofen, naproxen, uye celecoxib (asi iyo yakaderera inoshanda dosi yeNSAID inogara ichikurudzirwa). Imwe meta-ongororo yakawana kuti mamwe maNSAID akaita sepiroxicam uye azapropazone vane njodzi huru yekuita chepfu nepo yakaderera-dose ibuprofen ine yakaderera njodzi yehuturu. Pakazara, zvinogona kutaurwa kuti maNSAID anowanzosiyana zvakanyanya mukuchengeteka pane kushanda.
Nekuda kweakasiyana siyana esarudzo yekurwadziwa, zvakakosha kuti ubvunze mupi wezvehutano nezve yakanakisa yekurapa sarudzo. Chiremba kana mupi wezvehutano anogona kupa rakakodzera kurapwa kuraira kune chaiwo marapirwo mamiriro.
Kuvhavha uye mutengo kuenzanisa etodolac vs. ibuprofen
Mahwendefa eGeneric etodolac anowanzo kufukidzwa neMedare uye zvirongwa zveinishuwarenzi. Kana iwe uine mamiriro ekurapa senge arthritis, zvirongwa zveinishuwarenzi zvinogona kuvhara etodolac yemarwadzo. Mari yepakati yekutengesa etodolac inogona kusiyana zvichienderana nedosi, asi iwe unogona kubhadhara madhora makumi mashanu etodolac uchishandisa SingleCare coupon kuma Pharmacies ari kutora chikamu.
Sezvo ibuprofen inowanikwa pane-the-counter, mamwe mafomu anogona kunge asina kuvharwa nezvirongwa zveinishuwarenzi. Nekudaro, mazhinji Medicare Chikamu D uye zvirongwa zveinishuwarenzi zvinofanirwa kuvhara mushonga-simba ibuprofen mapiritsi zvichienderana nerejimeni yekurapa. Kazhinji, ibuprofen inodhura kupfuura etodolac. Shandisa imwecheteCare coupon ye ibuprofen kana uine mushonga kubva kune wako wekuchengeta hutano.
| Etodolac | Ibuprofen | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Hongu (mapiritsi emishonga-esimba) |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 300 mg 2 kusvika katatu pazuva zuva nezuva | 400 kusvika 800 mg katatu kanokwana kana pazuva |
| Chaizvoizvo Medicare copay | $ 0– $ 76 | $ 0– $ 22 |
| SingleCare mutengo | $ 40- $ 80 | $ 4– $ 24 |
Zvakajairika mhedzisiro mhedzisiro yeetodolac vs. ibuprofen
Iwo akanyanya kukanganisika mhedzisiro yeNSAIDs, kusanganisira etodolac uye ibuprofen, ndeyekusvotwa, indigestion (dyspepsia), kupatira, manyoka, uye kurwadziwa kwepamuviri kana mudumbu. Zvimwe kunze kwematumbo mhedzisiro mhedzisiro, maNSAID anogona zvakare kukonzera dzungu, kuzvimba mumaoko kana tsoka (edema), musoro, kuputika, uye kurira munzeve (tinnitus). Mhedzisiro mhedzisiro yeetodolac uye ibuprofen yakapfava uye inoenda yega.
Migumisiro yakakomba yeNSAID inogona kusanganisira kugadzirisa kwehutano, zvakadai sekumhanya kwakanyanya kana anaphylaxis, kubva kune zvinoshanda kana zvisingaiti zvigadzirwa. Zvimwe zvakakomba mhedzisiro zvinosanganisira gastrointestinal zvakashata mhedzisiro senge kubuda mudumbu kubuda uye maronda eronda . Bvunza wako mupi wezvehutano kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiropa muropa, kana kurasikirwa nemuviri zvakanyanya.
| Etodolac | Ibuprofen | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Nausea | Ehe | 1% -10% | Ehe | 1% -3% |
| Marwadzo emudumbu | Ehe | 1% -10% | Ehe | 1% -3% |
| Kuzvidya mwoyo | Ehe | 1% -10% | Ehe | 1% -3% |
| Kuzvimbirwa | Ehe | 1% -10% | Ehe | 1% -3% |
| Manyoka | Ehe | 1% -10% | Ehe | 1% -3% |
| Dzungu | Ehe | 1% -10% | Ehe | 1% -3% |
| Edema | Ehe | 1% -10% | Ehe | 1% -3% |
| Kutemwa nemusoro | Ehe | 1% -10% | Ehe | 1% -3% |
| Mapundu | Ehe | 1% -10% | Ehe | 1% -3% |
| Tinnitus | Ehe | 1% -10% | Ehe | 1% -3% |
Izvi zvinogona kunge zvisiri rondedzero izere yemhedzisiro mhedzisiro inogona kuitika. Ndokumbira utarise kuna chiremba wako kana mupi wezvehutano kuti udzidze zvimwe.
Kwayaka: DailyMed ( Etodolac ), Zuva Nezuva ( Ibuprofen )
Kubatana kwezvinodhaka etodolac vs. ibuprofen
Nekuti ivo vanovhara iyo COX-1 enzyme, iyo inoita basa mukugadzirwa kweplatelet uye kugwamba kweropa, NSAID dzinogona kukanganisa mhedzisiro yevanocheka ropa. NSAID dzinogona kuwedzera njodzi yekubuda ropa kubva kune antiplatelet vamiririri vakaita saasipurini uye anticoagulants senge warfarin.
Etodolac uye ibuprofen zvinogona kukonzera kuti muviri uchengete mvura uye kukanganisa kushanda kweitsvo. Nekuda kweizvozvo, maNSAID aya anogona kuwedzera kuwedzera kweropa. Kana iwe uri zvakare kutora yakakwira BP (antihypertensive) mishonga, senge lisinopril kana losartan, yako BP ingangoda kuongororwa uchitora NSAID.
Etodolac uye ibuprofen zvinogona kukanganisa kuti cyclosporine, digoxin, kana methotrexate inojekeswa sei kubva mumuviri. Kutora NSAID kunogona kutungamira kune yakawedzera njodzi yecyclosporine, digoxin, kana methotrexate chepfu.
Tsvaga kumwe kuwirirana kwekushandisa zvinodhaka pazasi.
| Zvinodhaka | Kirasi yemishonga | Etodolac | Ibuprofen |
| Aspirin | Antiplatelet | Ehe | Ehe |
| Warfarin | Anticoagulant | Ehe | Ehe |
| Lisinopril Captopril Ramipril | Angiotensin-inoshandura enzyme (ACE) inhibitor | Ehe | Ehe |
| Losartan Valsartan Olmesartan | Angiotensin receptor blocker (ARB) | Ehe | Ehe |
| Furosemide Hydrochlorothiazide | Diuretic | Ehe | Ehe |
| Lithium | Maitiro ekudzikamisa | Ehe | Ehe |
| Methotrexate Pemetrexed | Antimetabolite | Ehe | Ehe |
| Cyclosporine | Immunosuppressant | Ehe | Ehe |
| Digoxin | Cardiac glycoside | Ehe | Ehe |
Bvunza nyanzvi yezvehutano kune kumwe kudyidzana kwezvinodhaka.
Yambiro dze etodolac uye ibuprofen
Etodolac uye ibuprofen, kunge mamwe maNSAID, anogona kuwedzera njodzi yezviitiko zvakakomba zvemoyo zvemwoyo zvakadai sekurwadziwa kwemoyo nekurohwa. Kushandiswa kweNSAID kunofanirwa kudzivirirwa kana kuongororwa kune vanhu vane matambudziko emwoyo sekutadza kwemoyo, chirwere chemwoyo, uye kuwedzerwa kweropa.
Iko kushandiswa kwe etodolac kana ibuprofen kunogona kutungamira kune yakawedzera njodzi yezve gastrointestinal (GI) zviitiko zvakashata, senge kubuda mudumbu kubuda uye maronda eronda. Pasina kurapwa kwakakodzera, kuzvimba, uye kubuda ropa mune iyo GI turakiti zvinogona kuuraya. Vakwegura vanogona kuve nenjodzi yakakwira yezviitiko zvakakomba zveGI zvakashata.
NSAIDs hadzifanirwe kushandiswa musati mamberi kana mushure mekuita kwemoyo kudanwa coronary artery bypass graft (CABG) kuvhiya .
Avo vane chirwere cheitsvo vanogona kunge vari panjodzi yekuwedzera yezvinetso zveitsvo pavanotora maNSAID.
Tsvaga wako mupi wezvehutano nezve zvimwe zvekuchengetedza usati watora NSAID.
Inowanzo bvunzwa mibvunzo nezve etodolac vs. ibuprofen
Chii chinonzi etodolac?
Etodolac is nonsteroidal anti-inflammatory drug (NSAID) inoshandiswa kurapa kurwadziwa nekuzvimba. Iyo FDA inogamuchirwa kurapa osteoarthritis uye rheumatoid arthritis muvanhu vakuru. Generic etodolac inogona kuwanikwa chete nemushonga.
Chii chinonzi ibuprofen?
Ibuprofen inowanzozivikanwa nemazita emazita akadai saAdvil naMotrin. Inowanikwa pamusoro pe-iyo-piritsi yekurapa marwadzo epakati nepakati, fivhiri, uye kurwadza kwekuenda kumwedzi. Yakakwirira-simba ibuprofen inogona kuwanikwa nemushonga yekurapa kurwadziwa nekuzvimba kubva kuosteoarthritis uye rheumatoid arthritis.
Etodolac uye ibuprofen zvakafanana here?
Etodolac uye ibuprofen hazvina kufanana. Ipo ivo vari ese maNSAID, ivo vane misiyano mune dosing uye mashandisiro avo. Etodolac imishonga yemishonga inonyanyo shandiswa kuvanhu vakuru vane arthritis. Ibuprofen inowanikwa zvakanyanya seyed-the-counter drug yekurwadziwa uye kupisa muviri.
Etodolac kana ibuprofen iri nani here?
Iyo NSAID iri nani inoenderana nedosi iwe yaunotora uye zvauri kutora iwe. Inofananidzwa ne ibuprofen, etodolac inogara kwenguva refu mumuviri, uye nekudaro, inogona kutorwa kashoma pazuva. Zvisinei, inogona kunge yakadhura kupfuura ibuprofen. Kubva pane yako yakazara mamiriro, chiremba wako anogona kukurudzira mumwe pamusoro peumwe.
Ndinogona here kushandisa etodolac kana ibuprofen ndichiri nepamuviri?
Etodolac uye ibuprofen hazviwanzo kukurudzirwa panguva yekuzvitakura. Iko kushandiswa kweNSAID panguva yekuzvitakura kunosanganisirwa nenjodzi yakawedzera yekuremara kwekuberekwa kana kupererwa nepamuviri, kunyanya panguva yekupedzisira kubata pamuviri. Bvunza wako mupi wezvehutano kana iwe uri kufunga nzira dzekurapa uchiri nepamuviri .
Ndinogona here kushandisa etodolac kana ibuprofen nedoro?
Kunwa doro shoma kunogona kunge kwakanaka pane dzimwe nguva paunenge uchitora NSAID. Zvisinei, kunwa doro rakawandisa kunogona kutungamirira kune ngozi yakawanda yehutachiona hwemigumisiro yakaipa neNSAIDs. Doro uye NSAIDs inogona kutsamwisa dumbu uye ura hwemukati, izvo zvinogona kutungamira kune maronda kana kubuda ropa.
Etodolac inorwadza inouraya here?
Etodolac mushonga unorwadza unoshanda. Iyo inonyanya kushanda pakurapa kurwadziwa uye kuzvimba kunokonzerwa neArthritis. Izvo zvinobatsirawo pakurapa kurwadziwa kwakanyanya mushure meimwe nzira senge kuvhiyiwa mazino.
Etodolac yakasimba pane naproxen?
Kubudirira kweNSAID kunoenderana nedosi yakatorwa, pakati pezvimwe zvinhu. Zvinhu zvese zvakaenzana, etodolac uye naproxen zvakaenzana maererano nekubudirira. Zvinoenderana nekaviri-bofu zvidzidzo, etodolac uye naproxen ndizvo zvakafanana zvinobudirira yekurapa rheumatoid arthritis. Ose madhiragi aya anorerukirwawo zvakanaka maererano nemhedzisiro.
