Eliquis vs. Xarelto: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Eliquis naXarelto mazita maviri ezita anoshandiswa kurapa kusagadzikana kwekugwamba. Ose madhiragi aya ari emuromo anticoagulants akaiswa muboka remishonga inonzi factor Xa inhibitors. Ivo vanoshanda nekuvharira chinhu Xa, iyo inoburitsa thrombin, chinodikanwa chinogadzirwa mukugadzirwa kwe clot. Nekuvharira chinhu Xa, mishonga inoderedza kugadzirwa kwemachete. Enderera kuverenga pazasi kuti udzidze zvakawanda nezvaEliquis naXarelto.
Ndeupi mutsauko mukuru pakati paEliquis naXarelto?
Eliquis (apixaban) uye Xarelto (rivaroxaban powder) maNOACs (inoverengeka yemuromo anticoagulants), iri boka revatsva veropa. Ivo vanozivikanwa zvakare seDOAC (yakanangana nemuromo anticoagulants). Kusiyana neCoumadin (warfarin), inozivikanwa uye yekare anticoagulant, varwere vanotora Eliquis kana Xarelto havadi kuongororwa bvunzo dzeropa nguva nenguva kuti vatarise mazinga. Vaviri Eliquis naXarelto vanozivikanwa se factor Xa inhibitors, asi vane misiyano.
Eliquis naXarelto vese vanobvumidzwa neDFA yekushandisa mushonga uye vanowanikwa muzita rezita chete. Hapana generic inowanikwa zvakadaro yemushonga; zvisinei, generic Eliquis inofanira kuva inowanikwa munguva pfupi . Eliquis inogadzirwa naBristol-Myers Squibb. Xarelto inogadzirwa naJanssen Pharmaceuticals. Zvese zvinodhaka zvinoshandiswa nevakuru, uye muyero unosiyana nechiratidzo.
| Misiyano mikuru pakati paEliquis naXarelto | ||
|---|---|---|
| Eliquis | Xarelto | |
| Kirasi yemishonga | Chinhu Xa inhibitor | Chinhu Xa inhibitor |
| Brand / generic chinzvimbo | Brand | Brand |
| Chii chinonzi generic zita? | Apixaban | Rivaroxaban powder |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa, yekutanga pack | Hwendefa, yekutanga pack |
| Ndeipi muyero wakajairwa? | 2.5 mg kana 5 mg kaviri pazuva Chipimo chemushonga chinosiyana nechiratidzo | 10 mg kusvika 20 mg kamwe pazuva Chipimo chemushonga chinosiyana nechiratidzo |
| Yakareba sei iyo yekurapa? | Zvinosiyana | Zvinosiyana |
| Ndiani anowanzoshandisa mushonga? | Vakuru | Vakuru |
Unoda mutengo wakanakisa pana Eliquis?
Saina kuEququis mutengo wekuzivisa uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu akarapwa naEliquis naXarelto
Eliquis naXarelto vane zviratidzo zvinoverengeka zvakafanana - kuderedza njodzi yekurohwa uye embolism kune varwere vane nonvalvular atrial fibrillation (AFib, kana irregular heartbeat), kudzivirira yakadzika vein thrombosis (DVT) muvarwere vakave nehudyu kana mabvi kutsiva, bata DVT, bata PE, uye kudzikisira njodzi yekudzokorora DVT kana PE inotevera kurapwa kwekutanga.
Pamusoro pezvo, Xarelto ine zvimwe zviviri zvinoratidza. Xarelto inogona kudzivirira venous thromboembolism (VTE) uye kufa kwakabatana neVTE. Xarelto inogona kupihwa panguva yekugara muchipatara uye mushure mekuregedzwa muvakuru varwere vari panjodzi yezvinetso nekuda kwekutadziswa kufamba uye zvimwe zvinenjodzi. Nekudaro, Xarelto haifanirwe kupihwa kune varwere vane njodzi huru yekubuda ropa. Xarelto inoshandiswa zvakare neaspirin kudzikisa njodzi yezviitiko zvikuru zvemoyo zvakaita sekufa, kurwiswa nemoyo, uye kurohwa nevarwere vane chirwere chisingaperi checoronary arteriosis (CAD) kana peripheral artery chirwere (PAD).
| Mamiriro | Eliquis | Xarelto |
| Deredza njodzi yekurohwa uye embolism mune varwere vane nonvalvular atrial fibrillation | Ehe | Ehe |
| Prophylaxis yeakadzika vein thrombosis (DVT), iyo inogona kutungamira kune pulmonary embolism (PE), mune varwere vakave nekuvhiiwa kwechiuno kana mabvi. | Ehe | Ehe |
| Kurapa kweDVT | Ehe | Ehe |
| Kurapa kwe PE | Ehe | Ehe |
| Deredza njodzi yekudzokorora DVT uye PE zvichitevera kurapwa kwekutanga | Ehe | Ehe |
| Prophylaxis ye venous thromboembolism (VTE) uye VTE-inoenderana nerufu panguva yekuchipatara uye yekubuda-kuchipatara kuburitswa mune vanhu vakuru varwere vakabvumirwa chirwere chakakomba chekurapa avo vari panjodzi yezvinetso zvepromboembolic nekuda kwekutadza kufamba / zvimwe zvinhu zvine njodzi uye kwete panjodzi huru yekubuda ropa. | Kwete | Ehe |
| Mukubatana neaspirini, kudzikisa njodzi yezviitiko zvikuru zvemoyo: kufa kwemoyo, myocardial infarction (MI) uye kurohwa nevarwere vane chirwere chisingaperi checoronary arteriosis (CAD) kana peripheral artery chirwere (PAD) | Kwete | Ehe |
Eriquis kana Xarelto inoshanda zvakanyanya here?
TO kudzokorora uye meta-ongororo yeEliquis naXarelto yeacous venous thromboembolism (VTE) yakagumisa kuti zvese zvinodhaka zvaive zvakafanana asi kuti Eliquis inogona kuva yakachengeteka. Varwere vakarapwa naXarelto vakasangana nekubuda ropa zvakanyanya — zvikuru nezvidiki.
Chimwe chidzidzo akaongorora Eliquis naXarelto, uye Pradaxa (imwe nyowani anticoagulant) uye Coumadin (warfarin, anticoagulant yechinyakare). Vanyori vakapedzisa kuti Eliquis yaive neakanakisa kushanda, kuchengetedzeka, uye kuteerera kwemurwere.
Mushonga wakanakisa kwauri unogona kungotariswa nemupi wako wezvehutano, uyo anogona kufunga nezve mufananidzo uzere wehutano hwako (s), nhoroondo yezvokurapa, uye mimwe mishonga yaunotora iyo inogona kudyidzana naEliquis kana Xarelto.
Unoda akanakisa mutengo paXarelto?
Sign up kune Xarelto mutengo chenjedzo uye tsvaga kana mutengo uchinja!
Wana machenjedzo emitengo
Kuvhavha uye mutengo kuenzanisa kwaEliquis vs. Xarelto
Eliquis inowanzo kufukidzwa neinishuwarenzi uye Medicare Chikamu D, asi macopay anosiyana zvakanyanya. Chinyorwa chinowanzoitwa naEliquis chemwedzi mumwe chete (mahwendefa makumi matanhatu emashanu mg) angangodhura madhora mazana manomwe kana iwe uchibhadhara muhomwe. Iwe unogona kushandisa imwecheteCare kadhi kutenga Eliquis yemari iri pasi pe $ 450.
Xarelto inowanzo kuvharwa neinishuwarenzi uye Medicare Chikamu D, asi macopay anosiyana. Yakajairwa Xarelto kunyorerwa kwemwedzi mumwe chete (mahwendefa makumi maviri emakumi maviri emamiriyoni) yaigona kuita madhora mazana matanhatu nemakumi maviri pamutengo wekutengesa. Iwe unogona kushandisa imwecheteCare koponi kutenga Xarelto kweinenge $ 430.
| Eliquis | Xarelto | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | # 60, 5 mg mahwendefa | # 30, 20 mg mahwendefa |
| Chaizvoizvo Medicare Chikamu D copay | $ 19- $ 541 | $ 19- $ 508 |
| SingleCare mutengo | $ 447- $ 483 | $ 428- $ 471 |
Zvakajairika mhedzisiro mhedzisiro yeEliquis vs. Xarelto
Mhedzisiro yakajairika yemaviri madhiragi ane hukama nekubuda ropa, senge kubuda ropa mumhino, kusagadzikana (kupwanya), ropa mumurini, kana matadza ekubuda ropa. Iko kuitika kwekubuda ropa mhedzisiro kunogona kusiyana. Pazviitiko zvisingawanzoitika, kubuda ropa kunogona kuve kwakakomba kana kutyisidzira hupenyu.
Mimwe mhedzisiro mhedzisiro inogona kuitika neEliquis inosanganisira kuneta, kupera kwesimba, kushaya simba, kufema kwekufema, uye kusvotwa.
Mimwe mhedzisiro mhedzisiro inogona kuitika neXarelto inosanganisira yepamu kana yekurwadziwa musana, kuneta, dzungu, kurumwa, kushushikana, kushushikana, uye / kana kushaya hope.
Iri harisi rondedzero izere yemhedzisiro. Bvunza wako mupi wezvehutano kuti uwane rumwe ruzivo nezve zvakashata maitiro aEliquis naXarelto.
| Eliquis | Xarelto | |||
| Side Migumisiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kubuda ropa | Ehe | Zvinosiyana | Ehe | Zvinosiyana |
| Marwadzo emudumbu | Ehe | Hazvina kujairika | Ehe | 2.7% |
| Kuneta | Ehe | Zvakajairika | Ehe | 1.7% |
| Kupera simba | Ehe | Zvakajairika | Kwete | - |
| Kushaya simba | Ehe | Zvakajairika | Kwete | - |
| Kufema kwekufema | Ehe | Zvakajairika | Kwete | - |
| Kutambudzika shure | Kwete | - | Ehe | 2.9% |
| Dzungu | Ehe | Hazvina kujairika | Ehe | 2.2% |
| Kufunganya | Kwete | - | Ehe | 1.4% |
| Nausea | Ehe | Zvakajairika | Kwete | - |
| Kushungurudzika | Kwete | - | Ehe | 1.2% |
| Kusarara | Kwete | - | Ehe | 1.6% |
| Itching | Ehe | <1% | Ehe | 2.2% |
Kwayaka: DailyMed ( Eliquis , Chigadzirwa Monograph ( Eliquis ), Zuva Nezuva ( Xarelto )
Kubatana kwezvinodhaka kwaEliquis naXarelto
Eliquis naXarelto vanobatana nemimwe mishonga inogadziriswa neiyo enzyme. Kana enzyme inhibitor zvinodhaka zvikashandiswa naEliquis kana Xarelto, iwo mazinga eEliquis kana Xarelto mumuviri wako anowedzera, izvo zvinokuisa panjodzi yekuwedzera kubuda ropa. Kana iwe uchifanira kutora uyu mubatanidzwa wemishonga, zvinokwanisika kuti chiremba wako achaderedza dhizaini yako yeEliquis kana Xarelto uchinge uri pamishonga iyi miviri.
Kune rimwe divi, kana inducme inducers ikatorwa neEliquis kana Xarelto, kune kudyidzana uko iyo mishonga inogadzira Eliquis kana Xarelto metabolism nekukurumidza, uye haugone kuwana yakakwana yeiyo Eliquis kana Xarelto dose.
Zvakare, kushandisa Eliquis kana Xarelto nemamwe anticoagulants, antiplatelet madhiragi, NSAIDs (nonsteroidal anti-anogumbura zvinodhaka), uye mamwe antidepressants anogona kuwedzera njodzi yekubuda ropa.
Iri harisi runyorwa ruzere rwekubatana kwezvinodhaka. Bvunza wako mupi wezvehutano kuti uwane rumwe ruzivo.
| Zvinodhaka | Kirasi Yezvinodhaka | Eliquis | Xarelto |
| Itraconazole Ketoconazole Ritonavir | Yakasimba enzyme inhibitors (CYP3A4 uye P-gp) | Ehe | Ehe |
| Carbamazepine Phenytoin Rifampin Wort St. | Yakasimba enzyme inducers (CYP3A4 uye P-gp) | Ehe | Ehe |
| Citalopram Desvenlafaxine Duloxetine Escitalopram Fluoxetine Fluvoxamine Paroxetine Sertraline Venlafaxine | SSRIs uye SNRI antidepressants | Ehe | Ehe |
| Clopidogrel Enoxaparin Heparin NSAIDs (kwenguva refu) ● Aspirin ● Ibuprofen ● Meloxicam ● Nabumetone ● Naproxen Warfarin (coumadin) | Anticoagulants uye antiplatelets | Ehe | Ehe |
Yambiro dzaEliquis naXarelto
Eliquis naXarelto vane yambiro yebhokisi (nhema bhokisi), iri yambiro yakasimba inodiwa neDFA. Dzimwe yambiro dzinosanganisira:
- Kurega Eliquis kana Xarelto nguva isati yakwana kunowedzera njodzi yechiitiko chinovhara.
- Epidural kana musana hematoma inogona kuitika kune varwere vari kugamuchira neuraxial (pakati pe vertebrae) anesthesia kana kupenya kwemuzongoza. Iyo hematoma inogona kukonzeresa kwenguva refu kana zvachose kuora mitezo. Iyo njodzi yakakwira kune varwere vane epidural catheters, varwere vanotora mimwe mishonga inokanganisa kuyerera kweropa, varwere vane nhoroondo yekutambudzika / kudzokororwa punctures, uye / kana varwere vane nhoroondo yekuremara kwemusana kana kuvhiyiwa. Varwere vanofanirwa kugara vachiongororwa zviratidzo / zviratidzo zvekushaya simba kwehuropi (chiveve / kushaya simba kwemakumbo, ura / dambudziko redundira), uye kana paine nyaya dzinoitika, murwere anofanirwa kutsvaga kurapwa nekukurumidza.
- Kubuda ropa kunogona kuitika uye kunogona kuve kwakakomba (kukuru kubuda ropa) kana kunogona kuuraya. Kushandisa Eliquis kana Xarelto nemamwe madhiragi (anticoagulants, antiplatelet zvinodhaka, NSAIDs, SSRI uye SNRI antidepressants) zvinowedzera mukana wekubuda ropa. Varwere vane kubuda ropa vanofanirwa kutsvaga kurapwa nekukurumidza. Mushonga unofanirwa kumiswa mune varwere vane hemorrhage inoshanda.
- Reversal mumiriri inowanikwa, kudzoreredza mhedzisiro ye factor Xa inhibition.
- Eliquis kana Xarelto hazvikurudzirwe nevarwere vane prosthetic moyo mavharuvhu.
- Eliquis kana Xarelto hazvikurudzirwe seimwe nzira kune heparin yekurapa kwekutanga kwevarwere ve PE vane hemodynamic kusagadzikana (kuvhunduka / moyo kutadza).
- Eliquis kana Xarelto haifanire kushandiswa muvarwere vane hutatu-hwakanaka antiphospholipid syndrome (APS) nekuda kwekuwedzera njodzi yekugwamba.
- Kana uine chinetso chechiropa kana cheitsvo, taura nemupi wako wezvehutano usati watora Eliquis kana Xarelto.
Kushandiswa kwepamuviri:
- Kune mashoma data pamusoro pekushandiswa kwaEliquis kana Xarelto mukuzvitakura. Kurapa neEliquis kana Xarelto kunogona kuwedzera njodzi yekubuda ropa panguva yepamuviri nepamuviri, uye kuwedzera mukana wekubuda ropa mumwana / mucheche. Kushandisa Eliquis kana Xarelto panguva yebasa kana kuendesa mukati mevakadzi vanogamuchira epidural kunogona kukonzera epidural kana musana hematoma Iyo pfupi-inoshanda anticoagulant inogona kushandiswa kana zvichidikanwa. Bvunza OB-GYN yako nezvekushandiswa kwaEliquis kana Xarelto panguva yepamuviri. Kazhinji, mushonga uyu unongoshandiswa chete kana mabhenefiti akakurisa njodzi (semuenzaniso, mune dzimwe nhumbu dzine njodzi), uye nekutarisisa. Kana iwe uri kutoshandisa Eliquis kana Xarelto uye uone kuti ndiwe nhumbu , bvunza OB-GYN yako kutungamirwa.
Inowanzo bvunzwa mibvunzo nezve Eliquis vs. Xarelto
Chii chinonzi Eliquis?
Eliquis izita rechiratidzo anticoagulant (ropa rakatetepa) rinoshandiswa kudzivirira kana kurapa kugwamba kweropa.
Chii chinonzi Xarelto?
Xarelto izita-zita anticoagulant, uye inobatsira kudzivirira kana kurapa kugwamba kweropa.
Eliquis naXarelto vakafanana here?
Eliquis naXarelto vese vanozivikanwa se factor Xa inhibitors. Ivo vakafanana chaizvo, asi kwete chaizvo zvakafanana. Misiyano yakatsanangurwa pamusoro. Zvimwe zvinhu Xa inhibitors ndiPradaxa (dabigatran), Arixtra (fondaparinux), Savaysa (edoxaban), uye Bevyxxa (betrixaban).
Eriquis kana Xarelto ari nani here?
Zvidzidzo (ona pamusoro kuti uwane ruzivo) zvakaratidza kuti Eliquis naXarelto vanoshanda zvakafanana, kana kuti Eliquis inogona kunge ichinyatsoita. Eliquis anoita kunge ane njodzi yakaderera yekubuda ropa kupfuura Xarelto. Kumbira chiremba wako kana Eliquis kana Xarelto akakukodzera.
Ndinogona here kushandisa Eliquis kana Xarelto ndichiri nepamuviri?
Kazhinji, Eliquis naXarelto havashandiswe pakuzvitakura. Nekudaro, kumwe kusarudzika kunogona kuitika mune vamwe varwere vari panjodzi huru yekuvhara. Bvunza wako mupi wehutano.
Ndinogona here kushandisa Eliquis kana Xarelto nedoro?
Doro rinogona kutetepa ropa. Kana iwe ukatora Eliquis kana Xarelto ukanwa doro, izvi zvinogona kuwedzera njodzi yekubuda ropa. Zvakare, doro rinogona kuwedzera mamwe marapirwo. Iwe unogona kubvunza wako mupi wezvehutano kana zvakachengeteka kunwa, uye zvakadii, nemishonga iwe yaunotora uye nemamiriro ekurapa (s) aunayo.
Xarelto yakachipa kudarika Eliquis?
Pamubhadharo wemwedzi mumwe, mutengo weXarelto nemutengo weEliquis zvakafanana. Mutengo waEliquis naXarelto uine cheteCare koponi unotanga pa $ 447 uye $ 428. Generic yaEliquis inofanira kuwanikwa munguva pfupi.
Ndeipi ropa rakatetepa rakachengeteka kushandisa?
Ropa rakapfava rakachengeteka kana richishandiswa sekurairwa. Nekudaro, nechero ropa rakatetepa, pane mukana wekubuda ropa, kunyangwe rakakura kana rinotyisa hupenyu ropa. Ropa rakapfava rinogona zvakare kuyanana nemimwe mishonga. Bvunza mupi wako wezvehutano kuti uone kuti ndeipi ropa rakatetepa rakakodzerana newe.
Inobata chiropa here?
Zvishoma pane 1% yevarwere paEliquis mumakiriniki ekuedzwa kwakange kwakajairika kuyedzwa kwechiropa. Iwe unofanirwa kuzivisa chiremba wako usati watora Eliquis kana Xarelto kana uine matambudziko echiropa.
