Lovenox vs. heparin: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Unogona kunyorerwa Lovenox (enoxaparin) kana heparin kurapa kana kudzivirira ropa rinovhara. Lovenox uye heparin mishonga inobaya jekiseni iri chikamu cheboka rakakura remishonga inonzi anticoagulants. Seanticoagulants, kana kuwonda kweropa, Lovenox uye heparin anobatsira kurapa uye kudzivirira yakadzika vein thrombosis (DVT) uye pulmonary embolism (PE).
Ose maviri Lovenox uye heparin vane zvakafanana maitiro ekuita. Ivo vanoshanda nekusunga kune kadiki protein protein molecule inonzi antithrombin uye ichivharira zviito zve thrombin, factor Xa, uye mamwe maenzyme ane chekuita nekugwamba kweropa. Kunyangwe Lovenox akarongedzwa seakaderera mamorekuru uremu heparin (LMWH), haina kufanana neyakajairwa heparin.
Ndeupi mutsauko mukuru pakati paLovenox ne heparin?
Lovenox ndiro zita rekuti enoxaparin. Iyo LMWH inogadzirwa naSanofi-Aventis. Lovenox jekiseni subcutaneously (pasi peganda), uye inowanikwa mumatunhu maviri: 100 mg / ml uye 150 mg / ml.
Masipirisi akazara eLovenox anouya musimba rakasiyana uye anowanikwawo mu 300 mg / 3 ml yakawanda-mazamu magaba.
Lovenox ane hafu-yehupenyu yekutenderera 4,5 kusvika ku7 maawa mushure mekutonga, uye ayo anticoagulant mhedzisiro anogara kusvika maawa gumi nemaviri. Nekuda kwehafu yayo yehafu-yehupenyu uye zvinofungidzirwa mhedzisiro, Lovenox haidi kuongororwa kwakanyanya kana kutarisa kuitisa.
Heparin, inozivikanwawo seyakajairwa heparin kana isina kubviswa heparin (UFH), iri generic jekiseni. Heparin inoendawo nemazita ezita saHep-Lock.
Heparin inowanzo kupihwa intravenously (kuburikidza nevevheni) kana subcutaneously (pasi peganda). Inowanikwa mune imwechete-dhizaini uye akawanda-madhiza mafomu ane masimba akasiyana anokwanisa kusanganisira chiuru USP zviyero / ml, zviuru zveUSP zviyero / ml, uye zviuru gumi zveUSP zviyero / ml.
Inofananidzwa naLovenox, heparin ine ipfupi hafu-hupenyu hwe0,5 kusvika 2 maawa. Heparin inoda kupihwa kakawanda kupfuura Lovenox, uye inowanzo kupihwa muchipatara. Iyo anticoagulant mhedzisiro ye heparin inoda kuongororwa nekuti mhedzisiro yacho haina kufungidzira kupfuura yakaderera mamorekuru uremu heparin.
| Misiyano mikuru pakati paLovenox ne heparin | ||
|---|---|---|
| Lovenox | Heparin | |
| Kirasi yemishonga | Anticoagulant | Anticoagulant |
| Brand / generic chinzvimbo | Brand uye generic vhezheni iripo | Brand uye generic vhezheni iripo |
| Chii chinonzi generic zita? | Enoxaparin | Heparin izita rakajairika reHeparin Sodium ADD-Vantage |
| Ndeapi mafomu (s) ayo mushonga unouya? | Mhinduro yejekiseni | Mhinduro yejekiseni |
| Ndeipi muyero wakajairwa? | 40 mg subcutaneous kamwe pazuva. Chipimo chemushonga chinogona kusiyana zvichienderana nemamiriro ari kurapwa. | Mauniti zviuru zvishanu pasi pega maawa masere kusvika gumi nemaviri. Chipimo chemushonga chinogona kusiyana zvichienderana nemamiriro ari kurapwa. |
| Inguva yakareba sei kurapwa kwacho? | Mazuva manomwe, zvishoma kana zvishoma zvichienderana nemamiriro ari kurapwa | Mazuva manomwe, zvishoma kana zvishoma zvichienderana nemamiriro ari kurapwa |
| Ndiani anowanzoshandisa mushonga? | Vakuru, vana, uye vacheche | Vakuru, vana, uye vacheche |
Unoda akanakisa mutengo paLovenox?
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Mamiriro ezvinhu anorapwa naLovenox uye heparin
Ose maviri Lovenox uye heparin anotenderwa muU.S. kurapwa kwe venous thromboembolism (VTE) , mamiriro ayo anosanganisira yakadzika vein thrombosis uye pulmonary embolism. Ropa rakagwamba rinowanzo gadzira mumakumbo kana maoko (yakadzika vein thrombosis / DVT) uye inogona kuenda kumapapu uko kwaanozonogara mumidziyo yeropa (pulmonary embolism / PE).
Lovenox uye heparin anoshandiswa zvakare mukudzivirira kuwanda kweropa, kunyanya mushure mekuvhiyiwa sekuvhiyiwa kwemabvi kana kuvhiyiwa kwechiuno. Kuzorora kwemubhedha mushure mekuvhiyiwa ndeimwe yeakanyanya njodzi mikana yekuvhara ropa. Zvimwe zvengozi zvinokonzerwa nekugwamba kweropa zvinosanganisira nhoroondo yemhuri yezvirwere zvekuvhara ropa, nhumbu, kufutisa, kusvuta, uye gomarara.
Heparin inobvumidzwawo kudzivirira nekubata ropa rakagwamba rinogona kuumbika kubva atrial fibrillation . Zvakare, Lovenox inobvumidzwa kurapa uye kudzivirira kusagadzikana muvanhu vanoona mamwe marudzi echipfuva marwadzo (asina kugadzikana angina) uye kurwiswa kwemoyo (isiri-Q-wave myocardial infarction).
| Mamiriro | Lovenox | Heparin |
| Kurapa uye kudzivirira venous thromboembolism | Ehe | Ehe |
| Kurapa uye kudzivirira kweropa clots mushure mekuvhiyiwa | Ehe | Ehe |
| Kudzivirira uye kurapwa kwematambudziko kubva kuatrial fibrillation | Kunze-chitaridzi | Ehe |
| Kudzivirira kwezvinetso kubva kune isina kugadzikana angina uye kurwiswa kwemoyo | Ehe | Kunze-chitaridzi |
Ko Lovenox kana heparin inoshanda zvakanyanya here?
Lovenox uye heparin zvese zvinoshanda pakurapa nekudzivirira kuwanda kweropa. Ivo vanoshanda nenzira dzakafanana kubvumira ropa kuyerera zvakasununguka zvakanyanya. Kuda kweimwe mushonga pamusoro peumwe kunoenderana nemutengo, mhedzisiro, uye manejimendi.
Inofananidzwa ne heparini, Lovenox ane akareba hafu yeupenyu. Zvinoreva, inogara kwenguva yakareba uye inogona kupihwa kamwe chete zuva nezuva. Dosing inonyatso fungidzirwa neLovenox, kunyangwe varwere vane huremu hwemuviri hwakanyanya vachida kuwedzerwa dosing, senge jekiseni rimwe kaviri pazuva.
Mune meta-ongororo kubva ku Zvinyorwa zveThrombosis uye Haemostasis , enoxaparin uye isina kubviswa heparin yakafananidzwa nekudzivirira kuwanda kweropa muzvipatara varwere. Makumi mana emakiriniki emiedzo akaverengerwa meta-ongororo uye akaongorora huwandu hwevarwere mazana matatu nemazana matanhatu. Mhedzisiro yakawana kuti, tichienzanisa neparparin, enoxaparin yakadzora zvakanyanya kuwanda kweropa pasina kuwedzera njodzi yekubuda ropa kukuru.
Imwe bakoat yekushandisa Lovenox ndeyekuti iyo dosi inoda kugadziriswa mune varwere vane renal kutadza. Zvikasadaro, kune mukana wekuwedzera wekubuda ropa. Mukurapa kwekurapa, isina kubviswa heparin inosarudzwa kune vanhu vane hurema hweitsvo.
Chiremba wako anokupa anticoagulant yakanakisa yemamiriro ako. Iyo anticoagulant inoshanda kwazvo ichagadziriswa zvichienderana neyakaitika nhoroondo yako yekurapa.
Kuvhavha uye mutengo kuenzanisa kwaLovenox vs. heparin
Mazhinji Medicare uye zvirongwa zveinishuwarenzi zvichafukidza Lovenox. Nekudaro, inishuwarenzi iri mukana wekuvhara generic Lovenox, uye vangangotadza kubhadhara iyo yakazara mutengo. Wepakati mutengo wekutengesa weLovenox uri madhora mazana matatu nemakumi masere. Kana iwe uri kutenga jekiseni reLovenox rekushandisa pamba kubva kukhemisi, unogona kushandisa kadhi reLovenox SingleCare kuchengetedza mari. Panzvimbo pekubhadhara mutengo wakazara weLovenox, unogona kubhadhara isingasvike $ 75 yemakumi gumi nemajekiseni akafanirwa.
Heparin inowanzo kufukidzwa neMedare uye zvirongwa zveinishuwarenzi. Iyo zvakare inowanzo kuve isingadhuri pane Lovenox. Zvakadaro, avhareji wekutengesa mutengo we heparin iri $ 120, zvinoenderana nehuwandu uye muyero. Uine CouponCare koponi, unogona kuiwana isingasvike $ 50 kuma pharmacies anotora chikamu.
| Lovenox | Heparin | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 40 mg subcutaneous kamwe pazuva (huwandu hwegumi) | Zviyero zviuru zvishanu pasi pega maawa masere kusvika gumi nemaviri (huwandu hwegumi) |
| Chaizvoizvo Medicare copay | $ 5– $ 58 | $ 1– $ 3 |
| SingleCare mutengo | $ 71 + | $ 45 + |
Tora kadhi rekudzikisira chemishonga
Zvakajairika mhedzisiro mhedzisiro yeLovenox vs. heparin
Rwunonyanya kuzivikanwa mhedzisiro yeLovenox uye heparin jekiseni saiti maitiro. Mushure mekubaya Lovenox kana heparin majekiseni, unogona kurwadziwa, kusagadzikana, kutsamwa, kana kuzvimba uchitenderedza nzvimbo yejekiseni. Nekudaro, iyi mhedzisiro mhedzisiro inowanzove yakapfava uye inoenda yega.
Sezvo Lovenox uye heparin zvichidzivirira kugwamba kweropa, zvinogona kukonzera kubuda ropa mhedzisiro. Paunenge uchishandisa Lovenox kana heparin, unogona kusangana nekupwanya kazhinji. Anticoagulants inogona zvakare kukonzera kubuda ropa kwakanyanya. Zviratidzo zvekubuda ropa kwakanyanya zvinosanganisira kupwanya kwakanyanya uye ropa mune chigaro kana weti. Tsvaga kurapwa kana iwe ukaona zviratidzo zvekubuda ropa zvakanyanya.
Ona chati iri pazasi yemamwe mhedzisiro mhedzisiro.
| Lovenox | Heparin | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Marwadzo, kutsamwa, kuzvimba kwakatenderedza jekiseni saiti | Ehe | * | Ehe | * |
| Kubuda ropa | Ehe | * | Ehe | * |
| Yakakwirira chiropa makemikari | Ehe | * | Ehe | * |
| Nausea | Ehe | * | Kwete | - |
| Manyoka | Ehe | * | Kwete | - |
* haina kutaurwa
Kakawanda hakubvi pane data kubva kumusoro-kuenda-kumusoro kutongwa. Izvi zvinogona kunge zvisiri rondedzero izere yemhedzisiro mhedzisiro inogona kuitika. Ndokumbira utarise kuna chiremba wako kana mupi wezvehutano kuti udzidze zvimwe.
Kwayaka: DailyMed ( Lovenox ), Zuva Nezuva ( Heparin )
Kubatana kwezvinodhaka kwaLovenox vs. heparin
Lovenox uye heparin vane kusangana kwezvinodhaka zvakafanana. Platelet inhibitors, kana antiplatelet vamiririri, iri rakasiyana boka remishonga iro rinogona zvakare kubatsira kudzivirira kuwanda kweropa. Kubatanidza antiplatelets senge clopidogrel, ticagrelor, kana prasugrel naLovenox kana heparin kunogona kuwedzera njodzi yekubuda ropa.
Nonsteroidal anti-inflammatory drugs (NSAIDs) inogona kukanganisa iyo mashandiro emaplatelet . Ngozi yekubuda ropa inogona kuwedzerwa kana uchitora maNSAID pamwe neLovenox kana heparin. Udza chiremba wako kana uri kutora NSAID usati watanga kurapwa paLovenox kana heparin.
| Zvinodhaka | Kirasi yemishonga | Lovenox | Heparin |
| Aspirin Ibuprofen Indomethacin Celecoxib | Nonsteroidal anti-anogumbura zvinodhaka (NSAIDs) | Ehe | Ehe |
| Clopidogrel Ticagrelor Prasugrel Dipyridamole | Antiplatelet vamiririri | Ehe | Ehe |
Bvunza nyanzvi yezvehutano kune kumwe kudyidzana kwezvinodhaka
Yambiro dzaLovenox uye heparin
Anticoagulants saLovenox uye heparin inogona kuwedzera njodzi yekubuda ropa kukuru, kana kubuda ropa. Kubuda ropa kunogona kuve kwakakomba uye kunowanzo kuratidzwa nezviratidzo zvakaita seropa mune weti kana chigaro. Ngozi yekubuda ropa inogona zvakare kuve yakakwira kune vanhu vane nhoroondo yekutambudzika kwekubuda ropa.
Heparin inogona kukonzera heparin-inosimudzira thrombocytopenia (HIT) , chakakomba mamiriro anozivikanwa neakaderera maplatelet kuverenga. Nepo vanhu vasingawanzo kuve nezviratidzo zvakajeka zveHIT, iri dambudziko rinogona kutyisidzira hupenyu rinogona kukonzera kubuda ropa zvakanyanya kana kufa. Kuenzaniswa naLovenox, heparin ine njodzi yakanyanya yeHIT. Kushandiswa kweHeparin kunowanzo kuongororwa zvakanyanya nekuda kwechikonzero ichi.
Lovenox inotakura njodzi yakawedzera yemuzongoza epidural hematoma, kana kuunganidzwa kweropa rakatenderedza musana. Iyo spinal epidural hematoma inogona kutungamira kumatambudziko kana kuora mitezo. Iyo njodzi inowedzerwa kana iwe wakambove neyakare kana inodzokororwa musana kana epidural puncture; urikutora maNSAID, platelet inhibitors, uye anticoagulants; kana iwe uine inogara induru epidural catheter.
Bvunza wako mupi wezvehutano nezve zvimwe zvekuchengetedza zvine chekuita neLovenox uye heparin.
Inowanzo bvunzwa mibvunzo nezve Lovenox vs. heparin
Chii chinonzi Lovenox?
Lovenox inorwisa anticoagulant, kana ropa rakatetepa. Iyo zvakare yakarongedzwa seyakaderera mamorekuru uremu heparin. Lovenox inowanikwa muzvikamu zve100 mg / ml uye 150 mg / ml. Inowanzo kupihwa kamwe chete kana kaviri zuva nezuva sejekiseni rinotsvedza. Zita rakajairika raLovenox ndi enoxaparin.
Chii chinonzi heparin?
Heparin inozivikanwawo seyakajairwa kana isina kubviswa heparini . Inowanikwa mune zvakajairika kana zita-zita shanduro. Heparin inoitiswa seyakavharika kana jekiseni rinotsvedza. Inowanzo kupihwa muchipatara, kunyangwe mamwe marudzi eheparin anogona kupihwa kumba.
Ko Lovenox uye heparin zvakafanana here?
Lovenox uye heparin havana kufanana. Lovenox yakaderera mamorekuru uremu heparin (LMWH), iyo yakasiyana neyakajairwa kana isina kubviswa heparin (UFH). Kunyangwe Lovenox uye heparin ese ari maviri anticoagulants, ane mutsauko mukuumbwa uye FDA-inogamuchirwa mashandisiro.
Ko Lovenox kana heparin zvirinani?
Lovenox uye heparin zvese zvinoshanda pakurapa uye kudzivirira mamiriro ekuvhara ropa senge yakadzika vein thrombosis (DVT) uye pulmonary embolism (PE). Lovenox ine yakawanda inofungidzirwa dosing uye yekutarisa parameter uye nekudaro, inonyanya kufarirwa kushandiswa kwemusha. Iyo yakareba hafu-hupenyu hwaLovenox zvinoreva kuti inogona kudhonzwa kamwe zuva nezuva.
Inofananidzwa neLovenox, heparin inoda kuderedzwa kakawanda uye pamadosi epamusoro nekuda kweiyo ipfupi hafu-yehupenyu. Heparin yakachipa pane Lovenox, uye inowanzo kupihwa munzvimbo yekuchipatara uko kuongororwa kwemhedzisiro yakaipa kuri nyore.
Ndinogona here kushandisa Lovenox kana heparin ndichiri nepamuviri?
Lovenox kana heparin inowanzo chengeteka uye inoshanda pakurapa kusagadzikana kwetombo panguva yekuzvitakura . Ose anticoagulants haayambuki placenta. Nekudaro, yakaderera mamorekuru uremu heparin (LMWHs), saLovenox, anosarudzwa pakurapa kuwanda kweropa mune vakadzi vane nhumbu.
Ndinogona here kushandisa Lovenox kana heparin nedoro?
Vanoona nezvehutano vanokurudzira kudzikisira kana kunwa doro uchishandisa Lovenox kana heparin. Doro inogona kuita seropa rakatetepa , izvo zvinogona kukonzeresa kuwedzera njodzi yekubuda ropa kana doro rikasanganiswa nemushonga weanticoagulant.
Chii chingashandiswa pane heparin?
Low molecular weight heparins (LMWHs) anowanzo shandiswa panzvimbo ye heparin. Lovenox (enoxaparin), Fragmin (dalteparin), uye Innohep (tinzaparin) mienzaniso yeLMWHs inogona kushandiswa kurapa kana kudzivirira kuwanda kweropa. Arixtra (fondaparinux) ndeimwe antithrombotic mumiririri, yakasiyana neLMWH neUFH, iyo inogona kudzvinyirira factor Xa uye kurapa kugwamba kweropa.
Tungamira emuromo anticoagulants (DOACs), ayo anouya muchimiro chemapiritsi, anoshandiswawo zvakanyanya panzvimbo peheparin. Mienzaniso yeDoACs inosanganisira Xarelto (rivaroxaban powder), Pradaxa (dabigatran), uye Eliquis (apixaban).
Chii chinonzi Lovenox chinoshandiswa?
Lovenox (enoxaparin) inoshandiswa anticoagulation uye thromboprophylaxis. Inogona kubatsira kubata kana kudzivirira kuwanda kweropa kunogona kuumba mumidziyo yeropa. Lovenox inogona kubatsira kurapa kuwanda kweropa uko kunogadzika mumakumbo kana maoko (deep vein thrombosis) kana kugwamba kunozoiswa mumapapu (pulmonary embolism). Lovenox inobatsirawo kudzivirira kusagadzikana kubva kune isina kugadzikana angina uye mamwe marudzi ekurwadziwa kwemoyo.
Ko Lovenox mishonga ine njodzi huru here?
Lovenox ine njodzi-yakakura, kana yepamusoro-yekumwarira mishonga. Kunyangwe iri mishonga yakachengeteka, Lovenox inogona kukonzera kukuvara kwakanyanya uye kunetsekana kana ikashandiswa zvisirizvo. Kana Lovenox ikapihwa yakanyanya kudhizaini, pane mukana wekuwedzera wekubuda ropa nemhedzisiro. Lovenox inongofanirwa kushandiswa nemushonga uye gwara rakakodzera kubva kune anopa hutano.
