Celebrex vs. ibuprofen: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka uye misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Arthritis inozivikanwa nekukonzeresa kurwadziwa uye kurwadziwa. Kune mishonga yakawanda kwazvo kunze uko yekurwadziwa kweArthritis iyo inogona kuvhiringidza kuti ndeipi yekutora. Mishonga miviri yakajairika muNSAID (nonsteroidal anti-inflammatory drug) chikamu ndiCelebrex (celecoxib) uye ibuprofen.
NSAIDs dzinogona kushanda mukurapa osteoarthritis uye rheumatoid arthritis, pamwe nemamwe mamiriro akasiyana. Ose maviri maCelebrex uye ibuprofen anowanikwa mune generic fomu. Kunyange Celeelex ichingowanikwa nemushonga chete, unogona kutenga madosi ezasi ebuprofen pamusoro peiyo-counter. Yepamusoro doses yeIbuprofen inowanikwa nemushonga. Nekuti Celebrex uye ibuprofen vari mukirasi imwechete yemishonga, ivo vakafanana, asi zvakare vane mamwe misiyano inozivikanwa.
Ndeupi mutsauko mukuru pakati peLexapro vs. Zoloft?
| Misiyano mikuru pakati peCelebrex vs. ibuprofen | ||
|---|---|---|
| Celebrex | Ibuprofen | |
| Kirasi yemishonga | NSAID, COX-2 inhibitor | NSAID |
| Brand / generic chinzvimbo | Brand uye generic | Rx: generic OTC: brand uye generic |
| Chii chinonzi generic zita? Chii chinonzi zita rechiratidzo? | Generic: celecoxib | Mutengo: Motrin, Advil (OTC) |
| Ndeapi mafomu (s) ayo mushonga unouya? | Makapu (50, 100, 200, 400 mg) Fomu remvura yevana inosanganiswa neyemishonga | Mapiritsi ekunyora-simba: 400 mg, 600 mg, 800 mg OTC: 200 mg mapiritsi / makapisi / softgels, akasiyana chewables, zvinwiwa, uye madonhwe |
| Ndeipi muyero wakajairwa? | Vakuru: 200 mg zuva nezuva nechikafu; kunosvika mazana mana pazuva Imwe nzira: 100 mg kaviri pazuva Vana makore maviri zvichikwira: zvinoenderana nehuremu | Vakuru: 200 kusvika 800 mg katatu kana kana zuva nezuva nechingwa; huwandu hwehuwandu hunosiyana zvichienderana nemamiriro acho Vana: zvinosiyana zvichienderana nezera, huremu, uye kuumbwa |
| Inguva yakareba sei kurapwa kwacho? | Zvinosiyana: mavhiki kusvika makore | Zvinosiyana: mazuva kusvika mavhiki, vamwe varwere vanotora kwemwedzi kana makore |
| Ndiani anowanzoshandisa mushonga? | Vana vane makore maviri zvichikwira; vakuru | Vana vane mwedzi mitanhatu zvichikwira; vakuru |
Unoda mutengo wakanakisa paCelebrex?
Saina kuCelebrex yambiro yemitengo uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu akarapwa naCelebrex naIbuprofen
Celebrex, nonsteroidal anti-inflammatory drug (NSAID), iri yakaratidza kune inotevera mamiriro: osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis muvarwere makore maviri zvichikwira, ankylosing spondylitis, kurwadziwa kwakanyanya, primary dysmenorrhea, uye yemhuri adenomatous polyposis sechibatanidziro kune zvakajairwa kutarisirwa.
Ibuprofen zvakare iri NSAID uye inoratidzirwa kuzorora kwezviratidzo nezviratidzo zve osteoarthritis uye rheumatoid arthritis, nyoro kusvika pakati nepakati marwadzo, uye yekutanga dysmenorrhea.
| Mamiriro | Celebrex | Ibuprofen |
| Osteoarthritis | Ehe | Ehe |
| Rheumatoid arthritis | Ehe | Ehe |
| Juvenile rheumatoid arthritis (mune varwere vane makore maviri zvichikwira) | Ehe | Kwete |
| Ankylosing spondylitis | Ehe | Kwete |
| Kurwadziwa kwakanyanya | Ehe | Kwete |
| Yakanyanya dysmenorrhea | Ehe | Ehe |
| Inozivikanwa adenomatous polyposis sechirevo chekurapa | Ehe | Kwete |
| Hunyoro kusvika pakati nepakati marwadzo | Kwete | Ehe |
NSAID zvinodhaka zvinoshanda nekudzivirira prostaglandin (prostaglandin inokonzera kurwadziwa nekuzvimba) kubva pakugadzirwa. Prostaglandin inogadzirwa nema enzymes maviri, cyclooxygenase-1 (COX-1) uye cyclooxygenase-2 (COX-2).
Ko Celebrex kana Ibuprofen inoshanda zvakanyanya here?
Celebrex inozivikanwa sekusarudza COX-2 inhibitor. Ipo ichiri NSAID senge ibuprofen, Celebrex inovhara COX-2, kupesana nebuprofen, iyo inovhara ese ari maviri COX-1 uye COX-2. Izvi zvinorevei? COX-2 inhibitor inogona kuve nyore padumbu, ine njodzi yakaderera yekukonzeresa maronda emudumbu.
In zvidzidzo zvekiriniki pakubudirira, Celebrex yakaratidza:
- Akaderedza marwadzo akabatana muosteoarthritis varwere
- Yakaderedza marwadzo akabatana uye kuzvimba mu rheumatoid arthritis varwere
- Kuvandudza kwevarwere vane vechidiki rheumatoid arthritis
- Kuvandudza kwevarwere vane ankylosing spondylitis (mukurwadziwa kwakanyanya, chirwere chiitiko, uye kusagadzikana kwekushanda)
- Ruregerero rwepakati nepakati pakurwadziwa kwakakonzerwa nekurwadziwa kwekuvhiya kana dysmenorrhea
Mune kiriniki zvidzidzo zvekubudirira, ibuprofen kuratidzwa :
- Mhedzisiro yakafanana kune aspirin mune varwere vane osteoarthritis uye rheumatoid arthritis yekurwadziwa uye kuzvimba
- Ruregerero rwekurwadziwa kubva episiotomy, mazino maitiro, uye dysmenorrhea
Ndeipi mishonga inoshanda? Zvakaoma kutaura. Mune imwe kudzidza , Celebrex yakaratidzirwa kuve inoshanda senge ibuprofen yevarwere vane osteoarthritis yemabvi. Zvimwe zvidzidzo zvinoratidza ibuprofen kuti ibudirire, asi vamwe vachipedzisa Celebrex inogona kushanda zvakanyanya.
Panyaya yekuchengetedzeka, kiriniki miedzo yeCelebrex, pamwe neNSAIDs dzisingasarudze (senge ibuprofen) yemakore anosvika matatu dzakaratidza njodzi yakawedzera yezviitiko zvakakomba zvemoyo, myocardial infarction, uye sitiroko, izvo zvinogona kuuraya. Naizvozvo, ese maNSAID (anosanganisira ese Celebrex uye ibuprofen) anogona kunge aine hukama nenjodzi iyi. Zvakare, ese maNSAID, anosanganisira Celebrex uye ibuprofen, ane njodzi yakawedzera yezviitiko zveGI, sekubuda ropa uye maronda.
Mushonga wakanakira iwe unogona chete kusarudzwa nemupi wako wezvehutano, ndiani anogona kufunga nezve mufananidzo wese wehutano hwako (s), njodzi zviitiko, nhoroondo yehutano, uye mimwe mishonga yauri kutora.
Unoda yakanakisa mutengo paIbuprofen?
Saina kuIbuprofen mutengo wekuzivisa uye uone kana mutengo wachinja!
Wana machenjedzo emitengo
Kuvhavha uye mutengo kuenzanisa kweCelebrex vs. Ibuprofen
Celebrex inowanzo kufukidzwa neinishuwarenzi uye Medicare Chikamu D mune yayo generic fomu ye celecoxib. Chairo chinyoreso chingave chemakumi matatu macapsule e200 mg celecoxib. Mutengo wekunze kwehomwe ungangoita madhora mazana maviri nemakumi manomwe nemanomwe asi iwe unogona kuwana celecoxib yemadhora zana nemakumi mashanu neshanu nemashanu kumafarmasi anotora chikamu ane kopi reSingleCare.
Ibuprofen inowanzo kufukidzwa neinishuwarenzi uye Medicare Chikamu D, musimba remushonga we400 mg, 600 mg, uye 800 mg. Zvinyorwa zvechiremba zvinosiyana. Semuenzaniso, mutengo wekutengesa wemapiritsi makumi matatu e800 mg ibuprofen inodhura chero kupi kubva pamadhora 6-30. Uine SingleCare koponi, mutengo weibuprofen i $ 4-8.
| Celebrex | Ibuprofen | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe; generic | Ehe; simba remishonga |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe; generic | Ehe; simba remishonga |
| Standard muyero | 30, 200 mg capsules egeneral celecoxib | 30, 800 mg mahwendefa ebuprofen |
| Chaizvoizvo Medicare Chikamu D copay | $ 0-150 | $ 0-14 |
| SingleCare mutengo | $ 105-145 | $ 4-8 |
Side mhedzisiro yeCelebrex vs. Ibuprofen
Zviitiko zvinowanzoitika zvakashata zveCelebrex uye ibuprofen zvinosanganisira kurwadziwa mudumbu, manyoka, kuzvimba uye kutemwa nemusoro. Ona chikamu chekuyambira kuti uwane rumwe ruzivo nezve njodzi yemoyo uye njodzi yekubuda ropa kweGI.
| Celebrex | Ibuprofen | |||
| Side Migumisiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda * |
| Marwadzo emudumbu | Ehe | 4.1% | Ehe | 3-9% |
| Manyoka | Ehe | 5.6% | Ehe | 3-9% |
| Dyspepsia (indigestion) | Ehe | 8.8% | Ehe | 3-9% |
| Kutemwa nemusoro | Ehe | 15.8% | Ehe | 3-9% |
Kakawanda kwemhedzisiro yakaipa yeibuprofen haina kupihwa neruzivo rwezvinodhaka; chete izvo zviitiko izvi zvakaitika mu3-9% yevarwere.
Kunobva: DailyMed (Celebrex) , Zuva Nezuva ( ibuprofen )
Iri harisi runyorwa rwakakwana; mimwe mhedzisiro inogona kuitika. Tsvaga nemubatsiri wako wehutano kuti uwane ruzivo.
Kubatana kwemishonga kweCelebrex neIbuprofen
Celebrex uye ibuprofen zvine hukama hwakawandisa pamwe chete nemimwe mishonga yemishonga. Yese mishonga inobatana nevanoonda ropa senge Coumadin (warfarin), mimwe mishonga yeropa (ACE inhibitors, maARB, uye beta blockers), antidepressants, uye diuretics senge hydrochlorothiazide uye methotrexate. Bvunza wako mupi wezvehutano kuti akutungamire.
Doro rinofanira kudziviswa kana uchitora Celebrex kana ibuprofen. Kushandisa imwe yemishonga iyi nedoro kunogona kuwedzera njodzi yeGI (mudumbu) kubuda ropa kana kuzvimba. Iko kusanganisa kunogona zvakare kukonzera kukuvara kweitsvo kana kukundikana kweitsvo.
Iri runyorwa rudiki rwekudyidzana kwezvinodhaka. Bata wako mupi wezvehutano kuti uwane rumwe ruzivo.
| Zvinodhaka | Kirasi Yezvinodhaka | Celebrex | Ibuprofen |
| Coumadin (warfarin) | Anticoagulant | Ehe | Ehe |
| Zestril (lisinopril), Cozaar (losartan), nezvimwe | ACE inhibitors, maARB | Ehe | Ehe |
| Tenormin (atenolol), Toprol XL kana Lopressor (metoprolol) | Beta anovharira | Ehe | Ehe |
| Diflucan (fluconazole) | Antifungal | Ehe | Kwete |
| Lasix (furosemide), hydrochlorothiazide | Diuretics | Ehe | Ehe |
| Naproxen, Mobic (meloxicam) | Dzimwe NSAIDs | Ehe | Ehe |
| Methotrexate | Antimetabolite | Ehe | Ehe |
| Zoloft (sertraline), Paxil (paroxetine), Prozac (fluoxetine), Effexor (venlafaxine), Desyrel (trazodone), Elavil (amitriptyline), nezvimwe | Zvinodzvinyirira | Ehe | Ehe |
| Doro | Doro | Ehe | Ehe |
Yambiro yeCelebrex neIbuprofen
Celebrex inofanirwa kudzivirirwa mune varwere vane allergiki kune NSAIDs, pamwe nevarwere vari allergic kune sulfa. Ibuprofen inofanirwa kudzivirirwa mune varwere vane allergiki kune maNSAID.
Nekuti ese ari maviri maNSAID, Celebrex uye ibuprofen vane yambiro imwechete. Ivo vane yambiro yebhokisi (yambiro yakasimba sekudiwa neKudya neDrug Administration, kana FDA). Celebrex kana ibuprofen inogona kuwedzera njodzi yezviitiko zvakakomba zvemoyo, MI (myocardial infarction, kana chirwere chemwoyo), uye sitiroko, zvese izvo zvinogona kuuraya. Ese maNSAID ane njodzi yakafanana, iyo inowedzera iyo yakareba iwe kuishandisa. Varwere vane chirwere chemwoyo kana vane vane njodzi yemoyo njodzi vari panjodzi huru. Celebrex kana ibuprofen haifanire kushandiswa pakurwadziwa panguva yekuvhiyiwa arteri bypass graft (CABG) kuvhiya.
Zvakare mune yambiro yebhokisi ndeye njodzi yeakakomba GI, kana zviitiko zvemudumbu, zvinosanganisira kubuda ropa, ulceration, uye kupora kwemudumbu kana ura, izvo zvinogona kuuraya. Chero chezviitiko izvi zvinogona kuitika chero nguva, uye pasina yambiro zviratidzo. Vakwegura varwere uye avo vane nhoroondo yezvironda kana GI kubuda ropa vari pangozi yakanyanya yezviitiko zvakakomba zveGI.
Zvimwe zveCelebrex uye ibuprofen yambiro zvinosanganisira:
- Ngozi yemakemikari eropa akakwidziridzwa uye, kashoma, zvakanyanya kukanganiswa kwehuropa
- Zviitiko zvitsva kana kuwedzera kwehypertension (yakakwira BP). Shandisa nekuchenjerera muhutachiona hwevarwere; chengetedza kuwedzera kweropa zvakanyanya panguva yekurapa.
- Kuchengetedza kwemvura uye edema. Shandisa nekuchenjerera kune varwere vane fluid chengetedzo kana moyo kutadza
- Renal papillary necrosis / kumwe kukuvara kwetsvo nekushandisa kwenguva refu. Shandisa nekuchenjerera kune vakwegura, varwere vane hurema hwekushaya basa, moyo kutadza, chiropa kusagadzikana, uye varwere vanotora diuretics, ACE inhibitors, kana angiotensin II blockers.
- Anaphylactoid maitiro. Usashandise kune varwere vane Samteri wemutatu .
- Kuita kwakakomba kweganda kunogona kuitika senge exfoliative dermatitis, Stevens-Johnson syndrome (SJS), uye chepfu epidermal necrolysis (TEN), inogona kuuraya uye ikaitika pasina yambiro. Regedza Celebrex uye utsvage kurapwa nekukurumidza kana kuputika kana kugadzirisa kweganda kuchiitika.
Iko kune mashoma data pane maNSAID anoshandiswa mukuzvitakura. Iko kushandiswa kwemaNSAID ese, kusanganisira ese Celebrex uye ibuprofen, panguva yetatu trimester yepamuviri, inowedzera njodzi kuvharwa nguva isati yasvika ye fetal ductus arteriosus . Naizvozvo, NSAIDs hadzifanirwe kushandiswa mushure memasvondo makumi matatu ekuberekwa.
Bvunza wako mupi wezvehutano nezveCelebrex kana ibuprofen kushandiswa mukuzvitakura. Kana iwe uri kutotora Celebrex kana ibuprofen uye uone kuti iwe une nhumbu, bata wako wezvehutano mupi wekutungamira.
Iko kune mashoma data paCelebrex uye ibuprofen nekuyamwisa; bvunza chiremba wako kuti akutungamire.
Inowanzo bvunzwa mibvunzo nezve Celebrex vs. Ibuprofen
Chii chinonzi Celebrex?
Celebrex is nonsteroidal anti-inflammatory drug (NSAID) inoratidzirwa kune inotevera mamiriro: osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis muvarwere makore maviri zvichikwira, ankylosing spondylitis, kurwadziwa kwakanyanya, primary dysmenorrhea, uye yemhuri adenomatous polyposis sechirevo chenguva dzose. hanya.
Chii chinonzi Ibuprofen?
Ibuprofen iNSAID uye inoshandiswa kurapa zviratidzo nezviratidzo zve osteoarthritis, rheumatoid arthritis, nyoro kusvika pakati nepakati marwadzo, uye yekutanga dysmenorrhea.
Ko Celebrex neIbuprofen zvakafanana here?
Nekuti ese ari maviri maNSAID, iwo akafanana uye ane akafanana mhedzisiro mhedzisiro uye yambiro. Izvo zvakasiyana muzviratidzo uye mutengo. Ona kumusoro kuti uwane zvimwe nezve kufanana uye misiyano.
Celebrex kana Ibuprofen iri nani here?
Ose madhiragi anogona kushanda zvakanyanya pakurapa arthritis pamwe nemamwe mamiriro. Zvichienderana nemamiriro ezvinhu (a) auri kurapa, uye uchifunga nezve chero mamwe marapirwo uye njodzi zvinhu zvaunazvo, pamwe nemimwe mishonga yauri kutora, chiremba wako anogona kubatsira kukurudzira mushonga wakakodzera iwe.
Ndinogona here kushandisa Celebrex kana Ibuprofen ndichiri nepamuviri?
Kana iwe ukaona kuti une nhumbu uye uchishandisa Celebrex kana ibuprofen bata wako mupi wezvehutano kuti akurudzire.
Vakadzi vane pamuviri havafanirwe kushandisa maNSAID aya mushure memasvondo makumi matatu ekuberekwa. Kushandisa Celebrex uye ibuprofen panguva yetatu trimester yepamuviri kunogona kuwedzera njodzi yekuvharwa nguva isati yasvika ye fetal ductus arteriosus.
Ndinogona here kushandisa Celebrex kana Ibuprofen nedoro?
Kwete . Kushandisa imwe yemishonga iyi nedoro kunogona kuwedzera njodzi yeGI (mudumbu) kubuda ropa kana kuzvimba kwemudumbu. Iko kusanganisa kunogona zvakare kukonzera kukuvara kweitsvo kana kukundikana kweitsvo.
Ko Celebrex inoshanda kupfuura ibuprofen?
Ose madhiragi anogona kushanda zvakanyanya pakurapa arthritis marwadzo pamwe nemimwe mamiriro. Bvunza wako mupi wezvehutano kuti udzidze kuti ndeupi mushonga wakanakira iwe kupihwa mamiriro ako (s), nhoroondo yehutano, uye mimwe mishonga yaungave uchitora.
Sei vakatora Celebrex kubva pamusika?
Celebrex ichiri pamusika kubva nhasi. Vioxx (rofecoxib), mumwe mushonga wakafanana kunaCelebrex, aive kubviswa kubva kumusika nemugadziri wayo, Merck, mu2004, nekuda kwekuwedzera njodzi yezviitiko zvemoyo pamwe nekushandisa kusingaperi. Muna 2005, mumwe mushonga wakafanana, Bextra (valdecoxib), yaive akabvisa pamusika nemugadziri Pfizer nekuda kwezvikonzero zvakafanana.
Celebrex ndeye painkiller here?
Celebrex iNSAID (nonsteroidal anti-inflammatory) mushonga unobatsira nezviratidzo zvekurwadziwa uye kuzvimba kubva kune akasiyana mamiriro (ona pamusoro). Nekuti inongoshanda pane COX-2 enzymes, inogona kuve yakachengeteka mudumbu, kunyangwe pachine njodzi yeGI.
