Armodafinil vs. modafinil: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Iwe unogona kunetseka nekurara zvakanyanya mukati mezuva kana iwe ukashanda husiku hwekuchinja. Asi nekurapwa kwakakodzera senge Armodafinil (Nuvigil) kana modafinil (Provigil), unogona kuramba wakamuka uye unzwe kungwarira. Iyi mishonga inogona kupihwa kana iwe uchinge waonekwa uine switch yebasa kusagadzikana (SWD), narcolepsy, kana inodzivirira kurara kufema (OSA). Sevamuki-vanosimudzira vamiririri, armodafinil uye modafinil vane zvinokurudzira-zvakafanana mhedzisiro.
Kunyange nzira yavo chaiyo yekuita isingazivikanwe, armodafinil uye modafinil vanofungidzirwa kuti vanoshanda munzvimbo yepakati yetsinga (CNS) uye inosimudzira chiitiko che dopamine muuropi. Migumisiro yavo inogona kunge yakafanana nezvimwe zvinokurudzira zvakadai seamphetamine (Adderall) uye methylphenidate (Concerta). Zvisinei, ivo vakasiyana zvakasiyana pane zvimwe zvinokurudzira.
Ose ari maviri armodafinil uye modafinil ndiwo Chirongwa IV zvinodhaka izvo zvine mukana wakaderera wekushungurudzwa uye kuvimba. Izvo zvinhu zvinodzorwa zvinongowanikwa nemushonga.
Ndeupi mutsauko mukuru pakati pearmodafinil uye modafinil?
Armodafinil, inotengeswa pasi pezita rekuti Nuvigil, mushonga mutsva kana uchienzaniswa nemodafinil. Yakagamuchirwa mu2007 seR-enantiomer yemodafinil. Enantiomers mamorekuru ayo ari girazi mifananidzo yeumwe neumwe-funga kuruboshwe uye kurudyi-ruoko magurovhosi. Nenzira iyi, armodafinil ine chimiro chakasiyana chemakemikari ichienzaniswa nemodafinil.
Armodafinil inogona kuva nehafu yeupenyu hwakareba ichienzaniswa ne modafinil (zita rekuti Provigil). Mune zvimwe zviitiko, armodafinil inogona kutorwa semushonga wakasimba uine mhedzisiro yekumuka. Kunyange madhiragi ese ari maviri achigona kuve nemhedzisiro, mamwe mhedzisiro anogona kunge akajairika mune mumwe mushonga kana mumwe.
| Misiyano mikuru pakati pearmodafinil uye modafinil | ||
|---|---|---|
| Armodafinil | Modafinil | |
| Kirasi yemishonga | Inokurudzira-senge zvinodhaka Kumuka kusimudzira mumiriri | Inokurudzira-senge zvinodhaka Kumuka kusimudzira mumiriri |
| Brand / generic chinzvimbo | Brand uye generic vhezheni zviripo | Brand uye generic vhezheni zviripo |
| Chii chinonzi zita rechiratidzo? | Nuvigil | Provigil |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa remuromo | Hwendefa remuromo |
| Ndeipi muyero wakajairwa? | 150 mg kamwe pazuva | 200 mg kamwe pazuva |
| Yakareba sei iyo yekurapa? | Yenguva refu kana sekurairwa nachiremba | Yenguva refu kana sekurairwa nachiremba |
| Ndiani anowanzoshandisa mushonga? | Vakuru nevakuru vechidiki makore gumi nemanomwe zvichikwira | Vakuru nevakuru vechidiki makore gumi nemanomwe zvichikwira |
Unoda mutengo wakanakisa pane armodafinil?
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Mamiriro ezvinhu anorapwa nearmodafinil uye modafinil
Armodafinil uye modafinil mishonga inonyorerwa FDA-inogamuchirwa kurapa hope dzemasikati dzine chekuita nekurara, kushanduka kwebasa rekuita, uye kutadza kufema kufema. Aya mamiriro ekurapa anoonekwa nekushaya kukwana kwekuzorora kunoguma nekunyanyisa kurara. Ose madhiragi anovandudza kumuka kune avo vanorwisana nekuneta zvakanyanya uye kurara zuva rese.
Armodafinil uye modafinil zvakare akave akafundwa nekuda kwekunze-chitambi zvinangwa. Vamwe zvidzidzo ratidza kuti modafinil inogona kuve inoshanda kurapwa sarudzo yekuneta kunoitika semhedzisiro yegomarara nekenza kurapwa. Muvanhu vakuru vari kunyatso kurapwa kurapwa nekenza, modafinil inogona kubatsira kudzikisira kuneta kwakanyanya kubva chemotherapy.
Mune avo vane multiple sclerosis , madosi ezasi emodafinil anogona kuve anoshanda pakurapa zviratidzo zvekuneta. Nekudaro, yakawanda data inoratidza kuti modafinil haifanire kushandiswa seyekutanga-mutsara sarudzo yeichi chiitiko.
Zvimwe zvekusiya-zvinyorwa zvinoshandiswa zvinosanganisira kurapwa kwehutano hwepfungwa senge kuora mwoyo uye kucherechedzwa kusakwana-kusagadzikana kwehutano (ADHD). Armodafinil kana modafinil inogona kushanda pakurapa zviratidzo zvezvinetso izvi asi hazvikurudzirwe senzira dzekutanga dzekurapa.
| Mamiriro | Armodafinil | Modafinil |
| Narcolepsy | Ehe | Ehe |
| Shift basa kusagadzikana | Ehe | Ehe |
| Kurambidza kufema kufema | Ehe | Ehe |
| Kuneta kwakabatana neCancer | Kunze-chitaridzi | Kunze-chitaridzi |
| Multiple sclerosis-inoenderana nekuneta | Kunze-chitaridzi | Kunze-chitaridzi |
| Matambudziko epfungwa senge kushushikana uye ADHD | Kunze-chitaridzi | Kunze-chitaridzi |
Unoda mutengo wakanakisa pamodafinil?
Saina ma modafinil emitengo yemaonero uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Armodafinil kana modafinil inoshanda here?
Armodafinil uye modafinil zvakafanana zvinoshanda pakurapa hope kubva kumatambudziko ekurara senge narcolepsy, inotadzisa kufema kufema, uye shanduko yebasa rekuchinja. Zvisinei, armodafinil inogona kuva nemigumisiro yakareba kwenguva refu kana ichienzaniswa ne modafinil.
Mune gumi nemaviri-masvondo akasarudzika, kliniki kuyedzwa, ese ari maviri armodafinil uye modafinil kunatsiridza kurara mune zvidzidzo zvinoshanda nguva yekuchinja. Mhedzisiro yakawana kuti armodafinil uye modafinil zvaifananidzwa nechengetedzo yakafanana zvikoro.
Mune meta-ongororo uchienzanisa armodafinil uye modafinil yekudzivirira kufema kufema, zvese zvinodhaka zvakawanikwa zvichishanda pakurapa kurara. Varwere vanotora chero chinodhaka chinoshivirirwa mhedzisiro uye vane ruzivo rwakagadziriswa masikati.
Armodafinil yakaratidzirwa kuve iine yepamusoro plasma kuwanda mumuviri mushure mezuva. Matanho epamusoro earmodafinil mumuviri anogona kukonzeresa kumuka zvirinani uchienzaniswa ne modafinil.
Kunyangwe chero mushonga ungashandiswa semushonga wekurara zvakanyanya, zvakanaka kubvunza chiremba kuti vapiwe mazano ekurapa. Parizvino, hapana zvirevo zvakajeka zvinoti chimwe chinoshanda kupfuura chimwe.
Kuvhara uye mutengo kuenzanisa kwearmodafinil vs. modafinil
Armodafinil inowanzo sarudzwa se 250 mg piritsi inotorwa kamwe pazuva. Inowanikwa kwese semushonga wemageneric unovharwa neMedare uye zvirongwa zveinishuwarenzi. Generic Nuvigil inogona kudhura avhareji mutengo wekutengesa unopfuura $ 500. Uyu mutengo unogona kuburutsirwa pasi neSingleCare kadhi rekudzikisa. Panzvimbo pekubhadhara mitengo yakakwira, armodafinil inogona kutengwa zvakaderera se $ 277.
Zvichienderana nehurongwa hweinishuwarenzi, modafinil inogona kuvharwa. Muchokwadi, Medicare uye mazhinji inishuwarenzi zvirongwa zvinofukidza modafinil kune zvinotenderwa zvinangwa. Ivhareji mutengo we modafinil unogona kuita pamusoro pe $ 600. Pamapurmesi ari kutora chikamu, unogona kushandisa kadhi reSingleCare kuchengetedza mari. Kuchengetedza modafinil kunogona kukonzeresa mutengo wakaderera we $ 35- $ 280 zvinoenderana nekombiji yaunoshandisa.
| Armodafinil | Modafinil | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare? | Ehe | Ehe |
| Standard muyero | 150 mg mapiritsi | 200 mg mapiritsi |
| Chaizvoizvo Medicare copay | $ 15- $ 217 | $ 11- $ 392 |
| SingleCare mutengo | $ 277 | $ 35- $ 280 |
Zvakajairika mhedzisiro mhedzisiro yearmodafinil vs. modafinil
Mhedzisiro inowanzoitika inosanganisirwa nearmodafinil uye modafinil musoro wekurwadziwa, kuda kurutsa, dzungu, uye kushaya hope. Modafinil inogona kunge ichikonzera zvimwe mhedzisiro sekushushikana, kuzara kwemhino (rhinitis), manyoka, uye kurwadziwa musana.
Ose ari maviri mishonga anogona zvakare kukonzera mukanwa wakaoma, indigestion (dyspepsia), uye kusagadzikana. Mhedzisiro mhedzisiro inoenderana nekudzikira uremu inogona zvakare kuitika. Vamwe vanhu vanotora armodafinil kana modafinil vanogona kunzwa kuderera kwechido.
Zvimwe zvisingawanzo asi zvakakomba mhedzisiro zvinosanganisira allergic reaction senge kuputika uye kufema kwekufema. Psychiatric mhedzisiro mhedzisiro senge kushushikana kana psychosis zvinokwanisika. Tsvaga kurapwa kana iwe ukawana izvi mhedzisiro.
| Armodafinil | Modafinil | |||
| Side Migumisiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kutemwa nemusoro | Ehe | 17% | Ehe | 3. 4% |
| Nausea | Ehe | 7% | Ehe | gumi neimwe% |
| Kutya | Ehe | 1% | Ehe | 7% |
| Kusarara | Ehe | 5% | Ehe | 5% |
| Dzungu | Ehe | 5% | Ehe | 5% |
| Manyoka | Ehe | 4% | Ehe | 6% |
| Kutambudzika shure | Kwete | - | Ehe | 6% |
| Kuzara kwemhino | Kwete | - | Ehe | 7% |
| Kuzvidya mwoyo | Ehe | piri% | Ehe | 5% |
| Muromo wakaoma | Ehe | 4% | Ehe | 4% |
| Kufunganya | Ehe | 4% | Ehe | 5% |
| Kuderedza kudya | Ehe | 1% | Ehe | 4% |
Iri rinogona kunge risiri runyorwa rwakakwana. Bvunza chiremba wako kana wemishonga kuti uwane mhedzisiro.
Kwayaka: DailyMed ( armodafinil ), Zuva Nezuva ( modafinil )
Kubatana kwemishonga kwearmodafinil vs. modafinil
Armodafinil uye modafinil vanogovana akawanda emamwe mashandisiro emishonga. Iyi mishonga inogona kuita sevanokuchidzira iyo CYP3A4 enzyme uye inhibitors yeiyo CYP2C19 enzyme. Mune mamwe mazwi, anogona kukanganisa maitiro mamwe madhiragi anoitwa mumuviri.
Armodafinil uye modafinil inogona kuderedza kushanda kwe steroidal mishonga yekudzivirira . Dzimwe nzira dzekudzivirira nhumbu dzinokurudzirwa panguva yekurapwa nearmodafinil kana modafinil uye kwemwedzi mumwe mushure mekurega kwemishonga iyi.
Armodafinil uye modafinil inogona kuwedzera kubviswa kwecyclosporine kubva mumuviri. Kana ikatorwa pamwechete, kushanda kwecyclosporine kunogona kuderedzwa. Kune rimwe divi, armodafinil uye modafinil inogona kuwedzera mazinga emamwe madhiragi anozivikanwa seCYP2C19 substrates. Kuwedzera kwematanho emishonga kunogona kutungamira kumhedzisiro.
| Zvinodhaka | Kirasi Yezvinodhaka | Armodafinil | Modafinil |
| Ethinyl estradiol Norethindrone | Steroidal yekudzivirira | Ehe | Ehe |
| Cyclosporine | Immunosuppressant | Ehe | Ehe |
| Omeprazole Phenytoin Diazepam | CYP2C19 substrates | Ehe | Ehe |
Izvi zvinogona kunge zvisiri runyorwa ruzere rwe zvese zvinobvira kusangana kwemishonga. Bvunza chiremba nemishonga yose yaungave uri kutora.
Yambiro dzearmodafinil uye modafinil
Ose ari maviri armodafinil uye modafinil anogona kukonzera kukomba kwakanyanya. Iyi mishonga inofanirwa kumiswa nekukasira mune zviitiko zvekupenga kwakanyanya. Usatore mishonga iyi kana iwe uine chaunofungidzira kuti chisimbwa nechimwe chezvinhu zvavo zvinoshanda.
Maitiro earmodafinil kana modafinil angangoda kuchinjiswa kuitira kuti uvandudze kurara masikati. Ndichiri kugadzirisa madosi, kuramba uchirara kunogona kuitika. Naizvozvo, zvakakosha kudzivirira kutyaira kana kutora chikamu mune zvine njodzi zviitiko kana uchitanga kutanga mushonga senge armodafinil kana modafinil.
Armodafinil uye modafinil zvinogona kukonzera zviratidzo zvepfungwa kunyanya kune avo vane nhoroondo ye psychosis , kuora mwoyo, kana mania. Iyi mishonga inofanirwa kuongororwa kana kutomiswa mune zvakakomba zviitiko zvepfungwa.
Zvinodakadza-senge zvinodhaka zvinogona kukonzera mhedzisiro mumoyo uye nemoyo system. Avo vane BP yakakwira vangangoda kuongororwa kana vatanga kutanga armodafinil kana modafinil. Bvunza chiremba kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchirwadza.
Inowanzo bvunzwa mibvunzo nezve armodafinil vs. modafinil
Chii chinonzi armodafinil?
Armodafinil inozivikanwa zvakare nezita rayo rekuti Nuvigil. Armodafinil inoshandiswa kurapa zvakanyanyisa kurara kubva kune narcolepsy uye zvimwe zvinokanganisa kurara. Iyo inouya mu50 mg, 150 mg, 200 mg, uye 250 mg mapiritsi.
Chii chinonzi modafinil?
Modafinil ndiro zita rekuti Provigil. Modafinil ndeye FDA-inogamuchirwa kurapa kurara kwemasikati kunobva kumatambudziko ekurara. Inogona kurapa kutadzisa kufema kufema, narcolepsy , uye chinja kusagadzikana pabasa
Armodafinil uye modafinil zvakafanana here?
Armodafinil uye modafinil zvine zvinhu zvakafanana asi hazvina kufanana. Armodafinil ine iyo R-enantiomer yemodafinil. Modafinil ine musanganiswa werudzi rweR- uye S-modafinil.
Armodafinil kana modafinil iri nani here?
Armodafinil uye modafinil zvakafanana mukushanda pamwe nekuchengetedza. Zvisinei, armodafinil inogona kunge iine mazinga epamusoro mumuviri nekufamba kwezuva. Mhedzisiro yearmodafinil inogona kugara kwenguva yakareba ichienzaniswa ne modafinil.
Ndinogona here kushandisa armodafinil kana modafinil ndichiri nepamuviri?
Kwete. Armodafinil uye modafinil hazviwanzo kukurudzirwa panguva yekuzvitakura. Kurukurai nezvekurapa nzira dzenyu nachiremba kana mune nhumbu kana kuyamwisa.
Ndinogona here kushandisa armodafinil kana modafinil nedoro?
Hazvikurudzirwi kutora armodafinil kana modafinil uchinwa doro. Kunwa doro uri paarmodafinil kana modafinil kunogona kukonzeresa mhedzisiro.
Unogona kutora armodafinil uye modafinil pamwechete?
Armodafinil uye modafinil hazviwanzo kutorwa pamwechete. Ose ari maviri armodafinil uye modafinil ane zvakafanana zvinoshandiswa zvinoshandiswa. Kutora armodafinil uye modafinil pamwechete zvinogona kuwedzera njodzi yemhedzisiro.
Ko armodafinil inoratidzira pane bvunzo yemushonga?
Kwete. Kuedzwa kwezvinodhaka hakuwanzo kuvharira armodafinil. Armodafinil haina amphetamine saka kunyepa kwekunyepedzera kweamphetamine hakuwanzo.
Unogona here kutora armodafinil mazuva ese?
Armodafinil inoshanda zvakanyanya kana ichitorwa zuva rega rega. Zvinokurudzirwa kutora imwe chete yedhodhi yeArmodafinil panguva imwechete mazuva ese, kazhinji mangwanani.
