Chii chinonzi Xarelto?

Zvinodhaka Info

Kunyangwe iwe uchida post-yekuvhiya mishonga yekudzivirirakugwamba kweropakana kuderedza njodzi dzinokonzerwa neatrial fibrillation,Xareltomushonga unowanzo shandiswa seanticoagulant. Ropa-kutetepa rakananga muromoanticoagulantinoderedza iyonjodzi yekuvhara ropainokonzerwa nematambudziko akasiyana siyana, anosanganisira coronary artery chirwere uyepulmonary embolism.

Ndokumbirawo uverenge pazasi kuti uwane rumwe ruzivo paXarelto, muyero wayo uyemhedzisiro, uye kuti inofananidzwa sei nemimwe mishonga yekuchera ropa pamusika.

ChiiXarelto, uye chii chinoshandiswa?

Xarelto ndeimwe yezvazvinozita-zitamishonga yekubatana nerondedzero yekukuraanticoagulantzvinodhaka.Xareltoinoshandiswa zvakanyanya kudzivirirakugwambazvine chekuita nemoyo uyetsinga yeropamamiriro.Nezveutanonyanzvi munyika yose vakaraira izvi kupfuura Mamiriyoni makumi mana nguva kune avo vanoda mishonga yekuderedzakuvhara ropanjodzi.

Xareltoinozivikanwawo se rivaroxaban powder , uye hapana generic vhezheni yemushonga.Rivaroxaban powderarichinhu Nechekare inhibitoruye inosarudzwa seanticoagulant. Mushonga uyu unogadzirwa neJanssen Pharmaceuticals uye unongova mushonga-mushonga chete.

Izvo zvinobatsira avo vane akasiyana moyo nemoyo uyetsinga yeropamamiriro, kusanganisira:

• Atrial fibrillationkanakurova kwemoyo zvisina kujairika
• Coronary tsinga chirwere
• Yakadzika tsinga thrombosis(yakajairika njodzi shure-hudyu uyekuvhiya mabvi)
• Peripheral tsinga chirwere
• Pulmonary embolism
• Kuvhiya / kusavhiya muchipatara

AnticoagulationneXarelto

Mamiriro akasiyana siyana anoisa varwere panjodzi yekuvhara ropa, kubvaatrial fibrillationkune kumwe kuvhiya.Anticoagulantmishonga yakakosha mukuderedza iyo njodzi. Zvinoteveramamiriro ekurapainowanzo kurapwakuvhara ropauchishandisaanticoagulantsengeXarelto:

Yakadzika tsinga thrombosis

TOkuvhara ropakuumba mune yakadzika mutsinga zvinokonzerayakadzika tsinga thrombosis(DVT), kazhinji mumakumbo kana muchiuno. Njodzi zvinhu zveDVTinosanganisira :

• Kutsemuka kana kukuvara kwemhasuru kunosanganisira tsinga
• Kuvhiya kukuru (kunyanya mabvi /hudyu kutsiva kuvhiya)
• Kunonoka kuyerera kweropa
• Kuwedzera kweestrogen mazinga
• Chirwere chemwoyo / mapapu
• Gomarara
• Nhoroondo yemhuri

Kana ikasarapwa,DVTzvinogona kukonzera kuremara, zvirwere zvakakomba, uye mune zvakakomba zviitiko, kufa.Nezveutanovanopa kurairaXareltokuvarwere varinjodzi huruyekuvandudzaDVT.Xareltoinozotetepa ropa, ichigadzira kuyerera kuri nani kuburikidza netsinga.

Kana aDVTinofamba ichidarika neropa uye ichienda mumapapu, kuvharika kunodaidzwa kunzi a pulmonary embolism (PE) inoitika.Xareltoinogona kushandiswa kudzivirira nekubata maPS.

Atrial fibrillation

Inowanzozivikanwa seAfib, atrial fibrillation ndeimwe yeanorapwa zvakanyanyakurova kwemoyo zvisina kujairikamamiriro. Munhu ane AFib anorohwa zvisina kujairika mumakamuri epamusoro emoyo, zvichikonzera kushomeka kweropa kwakakodzera.

Varwere vane AFib vari pangozi yakanyanya yekugwamba kweropanekuda kweropa risina simba kuyerera kuenda uye kubva pamoyo. Kuti kuderedze njodzi, vanachiremba vanopa mishongaropa rinoondasengeXareltokune avo vane AFib.

Mushure mekuvhiyiwa

Kumwe kuvhiya kwakafanana nemabvi uyehudyu kutsivahuya nehure-kuvhiyanjodzi yekuvhara ropa. Vanachiremba vanogona kunyoreraXareltomushure mekuvhiyiwa kudzivirira kwakakosha kunetseka.

Zvinoita seiXareltobasa?

Xarelto(rivaroxaban powder) inononokakuvhara ropanekumisa yakatarwakugwambaChinhu chinonzi Xa. Kazhinji, kumisikidzwa kweX chikamu chekukweva icho chinogadzirakugwamba kweropa.Rivaroxaban powdermumiririri uyo anoshanda kudzikamisa iyo Xa factor's activation, pakupedzisira achichengeta ropa kubvakugwamba.

Iyo yakasimba iyo dose yerivaroxaban powder, iyo inodzivirira zvakanyanya iri paX factor. Iyo yakawedzera dosi inozopedzisira yamisa iyo Xa factor kugona kubatsira kuburitsakugwamba.

Sei kutoraXarelto

Xareltoinowanikwa mufomu yepiritsi uye madosi anosiyana zvichienderana nekurapa uye kuomarara kweiyokugwambanjodzi. Zvichienderana nezvinodiwa,XareltoMahwendefa anouya musimba ina:

• 2.5 mg
• 10 MG
• 15 mg
• 20 mg

Iyo mishonga ichatanga kuonda ropa mukati maawa mashoma mushure mekutora muyero wekutanga. Kana murwere akamira kuitora,Xareltoichapera mukati maawa makumi maviri nemana. Tevera zvirevo zvechiremba uye rairo yakapihwa naXareltopamusoro penzira yekumwa mushonga.

Iyi inotevera tafura inoratidza madhisiki akajairwa akatemerwa mamiriro akasiyana.

Mamiriro	Xarelto chipimo chemushonga (mg)	Kakawanda
AFib	15-20 MG	Kamwe pazuva (nechikafu)
DVT/ PE Kurapa	15-20 MG	15 mg kaviri pazuva nechikafu chemazuva makumi maviri nerimwe, uyezve 20 mg kamwe pazuva nechingwa
DVT/ PE Kuderedza Njodzi	10 MG	Kamwe pazuva
Coronary / Pulmonary Artery Zvirwere	2.5 mg	Kaviri pazuva, pamwe chete neaspirin

KubvaXareltoinowanzo kutorwa kamwe kana kaviri pazuva, zvakachengeteka kuitora zuva rega rega kunze kwekunge zvataurwa neimwe nzira nanezveutanomupi anonyora piritsi.

Kana uchinetseka kumedza mapiritsi, unogona kupwanyaXareltoMahwendefa uye uvasanganise nezvikafu zvakapfava zvekudya, semaapurauce, pakarepo usati washandisa. Nekudaro, zvingave zvakanaka kana iwe ukangoita izvi sezviri madikanwa. Kana zvichibvira, omedza piritsi rose.

Mashoma ezasi (2.5 uye 10 mg) eXareltoinogona kutorwa pasina hanya nechikafu, asi zvinowanzokurudzirwa kuitora pamwe nekudya kana zvichibvira. Kana mushonga wacho uri wepiritsi rimwe zuva rega rega, zvinokurudzirwa kuutora pamwe nekudya kwemanheru. Kana ikatorwa kaviri pazuva, vanachiremba vanokurudzira kuitora nechingwa uye iyokudya kwemanheru.

Kana iwe ukarasikirwa neiyo dose yeXareltouye urikutora iyo 15 mg kaviri regimen yezuva nezuva, tora muyero nekukurumidza paunenge uchirangarira pazuva rimwe chetero kuona 30 mg ichipedzwa. Kana iwe uchinge warasikirwa nedosi uye uri kutora 2.5 mg kaviri pazuva, ruka iro rakarasika dosi uye tangazve madosi panguva inotevera yakatarwa nguva. Kune mamwe maratidziro eakaenzana zuva nezuva Xarelto, tora iyo yakarasika dhizai nekukurumidza kana uchinge warangarira wozotangazve madosi kazhinji pazuva rinotevera Kana ukakanganwa kuitora kwemaawa anopfuura makumi maviri nemana, bata wakonezveutanomupiki kana wemishonga kune mirairo.

Zvakakosha kusamborega kutoraXareltopasina mvumo yechiremba.Xareltozvinogona kukonzera matambudziko kana akamiswa nekukasira, saka vanachiremba vanofanirwa kubatsira kururamisa varwere kubva pamushonga.

Panogona kuve nezvimwe zviratidzo zvekuregera mushure mekumiraXarelto. Zviratidzo zvinogona kuitika mukati maawa gumi nemaviri kusvika makumi maviri nemana asi zvinomira mukati mevhiki. Kurega zviratidzo kubvaXareltoinogona kusanganisira:

• Kutemwa nemusoro
• Dzungu uye kusvotwa
• Kuneta
• Mwoyo palpitations
• Kuwedzera kweropa

Izvo zvinokwanisika kunyanyisa pamusoroXarelto, uye mhedzisiro yacho inogona kuuraya. Kana murwere achinyudza zvimwerivaroxaban powderkupfuura zvakatemwa, vanogona kukura kubuda ropa zvakanyanya. Iyi ingangoita dambudziko rinouraya.

Xareltohaiuyi nemirairo chaiyo yekuchengetedza mushonga. Varwere vanofanira kuchengeta mapiritsi patembiricha yekamuriuye kure nehunyoro uye kupisa kukuru. Iyo mishonga inofanirwawo kuchengetwa pasingasvike kune vana vadiki, pamwe nekuparadzaniswa kubva kune imwe mishonga (kunyanya iri mubhodhoro rayo) kudzivirira kunetsa kukuvara kwakanyanya.

Xareltoruzivo rwekuchengetedza

Ona pazasi kuti uwane ruzivo rwakakosha nezve kuchengetedzeka maereranoXarelto.

Kurambidzwa

Xareltoinofanirwa kutorwa chete neavo vanoda kudzikisakuvhara ropanjodzi kubva kune yemoyo kanatsinga yeropamamiriro.

Nepo pasina kukwana kwakaringana kiriniki maringe nezve Xareltoanoshandiswa nevakadzi vane nhumbu , zvinogona kukonzera kubuda ropa muchibereko kana amai. Varwere vane nhumbu kana kuronga kuita nhumbu vanofanirwa kutaura navonezveutanonyanzvi usati watangaXarelto uye pamwe ichazopihwa mamwe anticoagulants neruzivo rwakawanda rwuripo muhuwandu hwevanhu.Kuyamwisazvinogona zvakare kunge zvisina kuchengetedzeka uchitora izvianticoagulant.

Yambiro

Pane yambiro mbiri dzakakomberedza kushandiswa kweXarelto.

• Kumisa kushandiswa kwemushonga kare kare kunogona kuwedzera njodzi yekunyanyisakuvhara ropa.
• Iyo FDA zvakare inoyambira kutiepiduraluye musana hematomas zvakaitika kune varwere vakatoraXareltoapo uchiita akumusanauye kugamuchira neuraxial anesthesia. Mhedzisiro yacho inogona kuve yekuremara zvachose.

Kana iwe wakarongerwa kuvhiyiwa, rega kutoraXareltomazuva maviri kana matatu pamberi pematanho makuru uye zuva rimwe pasati maitwa madiki. Varwere vanogona kutangazve mushonga mushure mekuvhiyiwa. Iko kune inoshandura mumiririri wehupenyu hunotyisidzira kubuda ropa nekuda kweXarelto inowanikwa seIv infusion, iyo inoshandiswa pamwe chete nematanho anotsigira anowirirana.

Mune Kurume 2019 kugadzirisa pakati paJohnson & Johnson naBayer,Xareltovashandisi vakagadzirisa anopfuura makumi maviri nemashanu ematare edzimhosva. Sutu iyi yakati vagadziri havana kunyevera vashandisi vezvakakomba mhedzisiro, kusanganisira kubuda ropa kusingadzoreki uye kubuda ropa. Izvo zvakanyanyamhedzisiroizvozvi zvakanyorwa pamushonga wekunyevera wemushonga.

Zvimwe zvinokanganisa

Bata chiremba wako nekukurumidzamazano ekurapakana ukasangana neneutachionakuXarelto. Zviratidzo zvinosanganisira mikoko, kunetseka kufema, uye kuzvimba munzeve, mhino, uye pahuro nzvimbo.

Izvi ndizvo zvakajairikamhedzisiroyekushandisaXarelto:

• Tsandanyama mhasuru
• Kupwanya kuri nyore
• Itching

Kana chimwe cheizvi chakakombamhedzisirokuitika, bata chiremba wako nekukurumidza:

• Kubuda ropa kwakanyanya uye kusingadzoreke
• Mhino dzemhino
• Rash kana kuchenesa
• Kunetseka kufema
• Kutemwa nemusoro uye nedzungu
• Marwadzo kana kuzvimba kwakatenderedza maronda
• Zviratidzo zvemuzongozakuvhara ropa(Kurwadziwa kumashure / chiveve, kurasikirwa kwedundira kudzora)

Kudyidzana

Iko hakuna zvekudya zvinorambidzwa zvinodiwa kana uchishandisaXareltosaka unogona kuenderera nedhayeti yako senguva dzose. Zvisinei, kunwa doro uchitoraXarelto unogona kuwedzera yakonjodzi yekubuda ropa. Kunwa doro kunowedzera ropa. Pamusoro pezvo, kuchinja kwechiropa kwechiropa kunokonzerwa nekunwa kunogona zvakare kuchinjaXarelto‘Kubudirira.

Zvinokurudzirwa kurega doro uchirapwakugwambanjodzi neropa rakatetepa.

Kune mashoma mashandisirwo emushonga nemushonga weropa-kutetepa.

• Anticoagulants uye Xarelto : Kutora mumwe mushonga wekuonda ropaXareltoinogona kuwedzera zvakanyanya njodzi yako yekubuda ropa kusingadzorwe.
• Aspirin uye Xarelto : Kunze kwekunge chiremba wako akuraira, dzivisa kutora aspirin uchiripoXarelto. Aspirin inopinza ropa, iro rinonyanya kuwedzera iyonjodzi yekubuda ropakana yawedzerwa kuXarelto. Nekudaro, vanachiremba vanogona kupa yakaderera-dhizaini aspirin regimen ine yakaderera dosi yeXarelto.

Xareltoinobatana nemishonga yakasiyana-siyana inotetepa ropa. Kana chiremba wako achida kunyoraXarelto, zvakakosha kuti vazive kana iwe ukatora chero anotevera emishonga, nekuti anogona kukonzera kusangana kwakanyanya:

• Clarithromycin
• Defibrotide
• Eliquis
• Nizoral
• Ritonavir
• Savaysa
• Warfarin(coumadin)
• Zydelig

Chii chausingafanire kutora nachoXarelto?

Dzivisa marwadzo akawanda anodzora kananonsteroidal anti-anogumbura zvinodhaka(NSAIDs), kusanganisira aspirin,naproxen, Excedrin, uyeibuprofen. Kana iwe uchida mushonga unodzikamisa marwadzo, acetaminophen (Tylenol) haina kuzivana kudyidzana nayoXarelto.

Dzivisa kutora Pepto-Bismol neXarelto, sezvo ichigona zvakare kuwedzera iyonjodzi yekubuda ropa. Mimwe mishonga yekurwadziwa pamoyo haina kuchengetedzeka kunwa nayoXarelto, kusanganisira cimetidine. Nekudaro, ichi chinorwadza pamoyo uye asidhi Reflux mishonga yakachengeteka:

• Famotidine (Tumamu, Pepcid)
• Omeprazole (Prilosec)

Xareltodzimwe nzira

Kune mishonga yakawanda-yekucheka ropa pamusika, uye yakonezveutanomupi achapa iyo yavanofunga kuti yakakunakira iwe.

• Eliquis vs. Xarelto : Mushonga wega wega unoshanda nenzira imwechete yekuvhara kugadzirwa kwekuvhara ropavamiririri. Eliquis 'zita regeneral iriapixaban, uye muyero wakajairika wakaderera paneXarelto. Zvidzidzo zvinoratidza kuti Eliquis inogona kuve yakachengeteka, zvichienderana nemurwere.
• Warfarin vs. Xarelto : Warfarininoshanda zvinobudirira kunyangwe ukarasikirwa nedosi, nepo uchishaya muyero weXareltozvinogona kukonzera matambudziko. Iko zvakare kune inowanikwa nyore nyore inodzosera mumiririri kana paitika kuwandisa, kunyangwe kuchinjika kwechokwadi kwechero anticoagulant kunopa kwavo kwakasarudzika matambudziko. Kusarudzwa kwewarfarininoda mwero weyero wakashata, saka kugara uchiongorora mwero weropa kunokosha.

Eliquis uyeXareltovese vane hupfupi hafu-hupenyu, zvichireva kuti mhedzisiro yemushonga inopera nekukurumidza.Warfarin(Coumadin) inogara kwenguva refu, saka akurasikirwa nedosihaina kusimba zvakanyanya, ichiita kuti ive yakachengeteka zvishoma mupfungwa iyoyo.

Zvisinei,warfarininoda macheki nguva nenguva kuti uone kukurumidza kwakokugwamba kweropakuve nechokwadi kuti iwe uri kuwana iyo chaiyo dosi. Kuchinja kwechikafu kunowedzera kana kudzikisa vhitamini K mumuviri kunogona kukanganisa chiyero chaunoda. Mimwe mishonga yakawanda uye zvinowedzera zvinowirirana nazvowarfarin. Mune ino kesi,Xareltouye Eliquis akachengeteka kushandisa.

Mushonga wega wega wekucheresa ropa wakachengeteka kushandisa munzira inorairwa nachiremba. Kana iwe uchida kuchinjira kumushonga wakasiyana, kurukura zvakanakira nekuipira kweumwe neumwe neakonezveutanomupi.

Maitiro ekuchengetedza paXarelto

Xarelto'S average retail price is $ 563.07 and most Medicare and insurance plans cover the cost. Varwere vazhinji vanozopedzisira vabhadhara pakati pe zero ne $ 40 mwedzi wega wega.

Kana iwe uchikodzera, unogona kusevha pamitengo neiyo Janssen CarePath Savings Chirongwa. Varwere vari pasi pechirongwa ichi vanobhadhara $ 10 paXareltozadza. Pane zvakawanda zvinodiwa kuti uve unokodzera, zvakanakira mabhenefiti gore rega rekarenda, uye varwere veMedare havakwanise kugamuchira kupihwa uku.

Janssen Sarudza imwe chirongwa chekugadzira chinogona kukubatsira kuchengetedza pairiXarelto. Kana iwe uchibhadhara zvinodarika madhora makumi masere nemashanu kuti uzadze bhodhoro rega rega, unogona kukodzera. Chirongwa ichi chakanangana nevarwere vasingakwanise kutenga mishonga nekuda kweinishuwarenzi blockade senge yakakwira mari inobviswa. Bata kwavari kuti uwane rumwe ruzivo nezve yavo chirongwa chekuchengetedza.

SingleCare inopawo macuponi ekuchengetedza nokutiXareltokuma pharmacies anotora chikamu munyika yose.