Kupindirana kwezvinodhaka zveCDD: Ko CBD yakachengeteka kutora nemishonga yekunyorera here?

Zvinodhaka Info

Kana iwe wakashanyira chitoro chinotengesa hutano uye zvigadzirwa zvekunaka nguva pfupi yadarika, ungangodaro wakacherekedza kuti zvigadzirwa zvine CBD, kana cannabidiol, zvinoita kunge hasha dzese. Oiri, chokoreti, zvinowedzera, kunyange zvinwiwa zvine kabhoni, zviri kuzadza masherufu — zvichinyengedza vatengi nezvikumbiro zvekuti kushandisa chimwe chezvinhu izvi kucharapa kushaya hope, kunoderedza kunetseka, kunoderedza kuzvimba, kana kurapa PTSD.

Uye vatengi vari kuitenga, sekutaura-mumwe mushumo uchangobva kuratidza wakaratidza izvozvo CBD kutengesa inotarisirwa kurova madhora gumi nematanhatu gore ra2026, kubva pamadhora anopfuura bhiriyoni rimwe chete muna 2018. Asi chii chaizvo chinonzi CBD, uye zvakachengeteka here kune vanhu vari kushandisa mishonga yekunyora? Usati waishandisa, zvakakosha kuti udzidze nezve zvingangoitika kusangana kweCDD zvinodhaka.

CBD mbanje here?

Kunyange CBD iri chimwe chezvinhu zvinoshanda mbanje, kushandisa CBD pachayo hakuzokwire kumusoro (chinhu icho chinoita icho chinonzi tetrahydrocannabinol, kana THC). CBD inongova mamorekuru mukati memhando dzakasiyana dzemuti wecannabis, uye panenge paine humbowo hwehushe uye kutanga kwekutsvaga kuratidza kuti kuburitsa kwakagadzirwa kubva mumorekuru iri kune zvimwe zvinobatsira pahutano.

CBD inofungidzirwa kuti inoshanda pane mamwe ma receptors muuropi hwako uye zvimwe zvikamu zvemuviri, munzira dzinogona kupedza marwadzo, kana kubatsira mamwe mamiriro ehutano, sekushushikana kwekubatwa kwehudiki. Nekudaro, sekune chero chigadzirwa chechisikigo, chokwadi chekuti chinobva kumiti hachiite kuti chive chisina mhosva. Kune vamwe vanhu, kunyanya avo vanonwa imwe mishonga yekunwa, kushandisa CBD kune njodzi. Iyo ine anticoagulant mhedzisiro inogona kutetepa ropa; inogona zvakare zvine mwero kudzikisa BP. Izvi zvinogona kuve nenjodzi kune vanhu vane mamwe marapirwo.

Mishonga yemakwenzi mishonga, anodaro Rita Alloway, Chiremba. , purofesa wekutsvagisa nephrology paYunivhesiti yeCincinnati College yeMishonga. Kungoita kuti [chimwe chinhu] chiri chemushonga… hazvireve kuti hazvigone kudyidzana nechero mishonga inogadzirwa nemishonga yaunogona kutora.

Ko CBD inopindirana nemishonga here?

Nyaya iripo: tacrolimus , mushonga unodzivirira muviri unoshandiswa kudzivirira kurambwa kwemuviri muvarwere vane moyo, chiropa, kana itsvo. CBD inopindirana ne metabolism yetacrolimus, sekureva tsvagiridzo yakaitwa naDr. Alloway , uyo anonyanya kugadzirisa post-transplant immunosuppression. Uye nekuti tacrolimus inorapa nzira yekurapa indekisi (zvichireva kuti hwindo riri pakati pekushanda uye huturu hwakanyanya kwazvo), kupindira uku kunogona kutungamira kumhedzisiro yezvakakomba zvisina kunaka (senge matambudziko eitsvo kana kurambwa kwechirongo), anodaro.

Iko kukosheswa mune yekutengesa inowanikwa CBD yakakwira zvakakwana kuti ikonzere kudyidzana uku? Humbowo hautaure chaizvo nenzira imwe kana imwe. Tsvagiridzo yaDr. Alloway yaisanganisira chiyero chakakura cheCDD chaisazowanikwa mune chigadzirwa chekutengesa. Zvisinei, zvinoratidza kuti kudyidzana kwezvinodhaka kuriko, anodaro. Uyezve, tacrolimus inogadziriswa mumuviri neboka rema enzymes anonzi cytochrome P450 uye CBD inozivikanwa inhibitor kwemaitiro aya. Zvinorevei izvo? Kana CBD ichitadzisa metabolism yetacrolimus, murwere anogona kupedzisira aine akanyanya-mazinga etacrolimus mumuviri. Mukuona kweizvi, anokurudzira chero munhu anotora tacrolimus kuti ataure neboka ravo rekudyara vasati vashandisa CBD. Usawane tariro dzako, kunyangwe-kushandisa mishonga yemakwenzi, kunyanya avo vane mikana yekudyidzana, inowanzo shamiswa navanachiremba vanotarisira kuisirwa vanogamuchira (kusanganisira Dr. Alloway).

Kana ari mamwe madhiragi, zvakanaka, mazhinji haasati adzidzwa. Pane humbowo hwepakutanga hwekuti CBD inogona kuve nemhedzisiro yakafanana nejusi remuzambiringa, zvichikanganisa mashandisiro anoita muviri wako zvinodhaka, uye kukwidza maseru emishonga iyoyo mumuviri wako. Uye, nekuticytochrome P450 inokonzera metabolism yemishonga yakawanda , enderera nekungwarira usati wasanganisa chero mushonga wekurapa neCBD, Dr. Alloway anodaro.

Zvakadii nezveBDD's yekurapa mabhenefiti?

Kunyangwe isina-yakanyanya-kunaka nhau nezveCDD yevarwere vanoshandisa tacrolimus, kune vamwe vanhu, CBD iri kunyatso shandura hupenyu nenzira yakanaka. Mu2018, semuenzaniso, iyo CBD-yakatorwa mishonga Epidiolex yakagashirwa FDA tendero yekurapa kwaLennox-Gastaut syndrome uye Dravet syndrome, maviri asingawanzo uye akaomarara mafomu epfari.

Asi vanoti CBD inobatsira pakurapa kwehutano hwepfungwa uye hwepfungwa, usapfuure muster, anodaro Roger McIntyre, MD , purofesa wezvepfungwa uye wemishonga paYunivhesiti yeToronto.

Iko hakuna basa izvozvi kweCBD mukugadzirisa kusagadzikana kwepfungwa kwandino [kurapa], senge kushushikana, bipolar kusagadzikana ... kushushikana uye ADHD, anodaro. Isu hatina humbowo hunotsigira [i].

Uyezve, mishonga yakawanda yemishonga inoshandiswa kugadzirisa mamiriro aya inogadziriswa ne cytochrome P450, zvichiita kuti zvive nyore kwazvo kuti CBD inogona kupindira-pane kuwedzera-kurapwa.

Dr. McIntrye, uyo akabatanidza a 2018 kudzidza iyo yakagumisa kuti vatapi vezvehutano vanoda rumwe ruzivo nezve kudyidzana kwezvinodhaka-zvinodhaka neCDD uye psychotropic mishonga, inotaura zvakawanda zvemashoko kunze uko zvinovhiringidza uye zvinopesana. Naizvozvo, anodzokorora chirevo chaDr. Alloway chekuti zvakangwara kuti varwere vabvise kushandiswa kweCBD nachiremba wavo vasati vazvipa.

[Mupi] anoziva munhu uye anoziva mamwe marapirwo avanogona kana asiri kutora, anotsanangura Dr. McIntyre. Vane maonero epanoramic emishonga yemurwere, uye vangave ne [zano riri nani] rekuti murwere ari kutora mumwe mushonga uyo unogona kuve nekudyidzana.