Trintellix vs. Zoloft: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Trintellix naZoloft ndidzo nzira mbiri dzekurapwa kweimwe yematambudziko epfungwa muAmerica, kushushikana kukuru. Huru kushushikana kwekushushikana (MDD) kunoonekwa nenguva yemasvondo maviri apo murwere anonzwa kushushikana kana kurasikirwa kwechido mumabasa anowanzounza mufaro. MDD inogona kukonzera kukanganisika kukuru kune hutano hwepfungwa. Inogona zvakare kukonzera nyaya nekurara, kudya, kuisa pfungwa, uye simba.
Trintellix (vortioxetine) inoonekwa se serotonin modulator uye inosimudzira uye ndeye pharmacologically yakasarudzika kana ichienzaniswa nezvimwe zvinodzvinyirira. Zoloft.
Ndeupi mutsauko mukuru pakati peTrintellix vs. Zoloft?
Trintellix imushonga yemishonga inoratidzwa mukurapa kwehukuru kushushikana kwepfungwa. Iyo inorondedzerwa se serotonin modulator uye inosimudzira, ichiita kuti ive yakasiyana nedzimwe mishonga yekudzvinyirira iripo pari zvino. Nepo iyo chaiyo mashandiro ekuita ari akaomarara kupatsanura, inofungidzirwa kuwedzera serotonin chiitiko kuburikidza nekudzivirira kweserotonin mutakuri muiyo neuron synapse. Izvo zvakaratidzirwa kuvharidzira akawanda serotonin receptors, nepo zvakare ichikurudzira imwe chete serotonin receptor, 5-HT1A. Nzvimbo dzepamusoro dzeserotonin inowanikwa inosanganisirwa nekunatsiridzwa kwemanzwiro uye masimba emagetsi.
Trintellix pakutanga yakaunzwa kumusika pasi pezita rekutengeserana Brintellix, asi kunetsekana nezve zvingangoitika zvikanganiso nekuda kwekufananidzwa kuri muzita neropa rakapfava Brilanta yakatungamira iyo FDA kuchinja zita rayo muna Chikumi wa 2016. Trintellix inowanikwa sehwendefa remuromo musimba re 5 mg, 10 mg, uye 20 mg.
Zoloft, uye yayo generic fomu sertraline, zvakare iri mishonga yemishonga inoratidzwa mukurapa kwekushungurudzika. Zoloft inorondedzerwa senge yakasarudzika serotonin reuptake inhibitor uye inoshanda nekuvharira iyo reuptake yeserotonin pane iyo neuronal synapse.
Zoloft inowanikwa sehwendefa remuromo musimba re25 mg, 50 mg, uye 100 mg. Iyo zvakare inowanikwa mune yemumuromo yakanyatsogadziriswa mhinduro iyo 20 mg / ml.
| Misiyano mikuru pakati peTrintellix vs. Zoloft | ||
|---|---|---|
| Trintellix | Zoloft | |
| Kirasi yemishonga | Serotonin modulator uye inosimudzira | Inosarudza serotonin reuptake inhibitor |
| Brand / generic chinzvimbo | Brand inongowanikwa chete | Brand uye generic inowanikwa |
| Chii chinonzi generic zita? | Vortioxetine | Sertraline |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa remuromo | Oral piritsi, yakanyatsogadziriswa mhinduro yemuromo |
| Ndeipi muyero wakajairwa? | 20 mg zuva nezuva | 50 mg zuva nezuva |
| Inguva yakareba sei kurapwa kwacho? | Mwedzi kusvika makore | Mwedzi kusvika makore |
| Ndiani anowanzoshandisa mushonga? | Vakuru | Vana nevechiri kuyaruka |
Mamiriro ezvinhu akarapwa naTrintellix vs. Zoloft
Trintellix inongotakura chiratidzo chimwe chakabvumidzwa, kushushikana kukuru kwekushungurudzika. Zoloft inoratidzwa zvakare mukurapa kwekushungurudzika kukuru kwekushungurudzika, asi ine zvimwewo zvinoshandiswa zvakare.
Zoloft inogamuchirwa mukurapa kwekusaziva-kusagadzikana kusagadzikana pamwe nehutano hwevanhu kusagadzikana. Izvo zvakare zvinogamuchirwa kurapa zviratidzo zvekuvhunduka kusagadzikana uye post-inoshungurudza kusagadzikana kusagadzikana (PTSD). Zoloft ine akawanda asiri-echiratidzo anoshandisa, kana mashandisiro asina kubvumidzwa zviri pamutemo neKudya neDrug Administration (FDA). Izvi zvinoshandiswa-zvisiri-zvinoshandiswa zvinosanganisira zvakajairika kusagadzikana kusagadzikana (GAD), kupatsanura kusagadzikana kusagadzikana, kupisa kunopisa kwakabatana nekuguma kuenda kumwedzi, uye ejaculation isati yakwana.
Iyi tafura inotevera inonyora zvimwe zvekushandisa kunozivikanwa kwaTrintellix naZoloft. Chiremba wako chete ndiye anogona kusarudza kuti ndeupi mushonga ungave wakakodzera mamiriro ako.
| Mamiriro | Trintellix | Zoloft |
| Huru kushungurudzika kusagadzikana | Ehe | Ehe |
| Kucherekedza kusagadzikana kusagadzikana (OCD) | Kwete | Ehe |
| Kushungurudzika kwevanhu munharaunda | Kwete | Ehe |
| Chirwere chekuzvidya mwoyo | Kwete | Kunze-chitaridzi |
| Kuparadzanisa kunetseka kusagadzikana | Kwete | Kunze-chitaridzi |
| Panic kusagadzikana | Kwete | Ehe |
| Post-inoshungurudza kusagadzikana kusagadzikana | Kwete | Ehe |
| Kupisa kunopisa kwakabatana nekuguma kuenda kumwedzi | Kwete | Kunze-chitaridzi |
| Nguva isati yakwana ejaculation | Kwete | Kunze-chitaridzi |
| Premenstrual dysphoric disorder (PMDD) | Kwete | Ehe |
Trintellix kana Zoloft inoshanda here?
Vatsvakurudzi vakatsvaga kuenzanisa kushanda uye kushivirira kwevanodzvinyirira zvakanyanya. Kuregedza mwero wezvinodzvinyirira zvinodhaka zvemhando dzakasiyana zvinogona kuve chikonzero chekushushikana kana vatapi vezvehutano vachisarudza marapirwo evarwere vavo.
TO meta-ongororo uchifananidza akawanda anodzvinyirira mune zvese kushanda uye kushivirira. Izvo zvinoshandiswa zvinoshandiswa zveTrintellix neZoloft zvaisanganisira. Vatsvagiri vakaona kuti ese antidepressant ainyanya kushanda kupfuura placebo. Trintellix yakaverengerwa mune runyorwa rweanodzvinyirira anoshanda kupfuura mamwe, nepo Zoloft anga asiri. Nekudaro, ese ari maviri madhiragi akawanikwa ari mamwe emamwe anodzvinyirira antidepressants, zvichitungamira kudzikisa kuregedza mwero.
Yakaparadzaniswa ongororo yemabhuku akatarisa Trintellix senzira yechipiri yekurapa kune avo vanokundikana kuwana mhinduro yakakwana kumaSSRIs saZoloft. Kuongorora uku kwakaongorora varwere vaive nemhinduro isina kukwana kune imwechete kurapwa neSSRI uye vakachinjirwa kune imwe nzira yekurapa. Avo vakachinjira kuTrintellix vakaona yakakwira kuregererwa mitengo kana ichienzaniswa nedzimwe nzira dzokurapa.
Trintellix inoita kunge ingango fanika, kana isiri yepamusoro kune, SSRI senge Zoloft. Iko kushiviririka kwemaviri madhiragi kuri kuita kwakanaka kana uchienzaniswa nemamwe anodzvinyirira akazara. Chete mupi wako wekuchengetedza hutano ndiye anogona kusarudza kuti ndeupi mushonga wakakukodzera.
Kuvhara uye kuenzanisa kwemutengo weTrintellix vs. Zoloft
Trintellix imishonga yemishonga inowanzo kuvharwa neMedare uye zvirongwa zveinishuwarenzi zvekutengesa. Mutengo wekunze kwehomwe wemwedzi mumwe weTrintellix 20 mg unogona kunge wakakwira kunge $ 660. Neponi kubva kuSingleCare, unogona kubhadhara isingasviki $ 400.
Zoloft zvakare iri mishonga yemishonga iyo inowanzo kufukidzwa neese ari maviri Medicare uye ezvokutengeserana zvirongwa zvemishonga. Mutengo wekunze-muhomwe wezita-zita Zoloft unogona kunge wakakwira kunge $ 105, asi nekoponi kubva kuSingleCare, unogona kubhadhara zvishoma seUS $ 10 yeiyo generic.
| Trintellix | Zoloft | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 30, 20 mg mahwendefa | 30, 50 mg mahwendefa |
| Chaizvoizvo Medicare copay | Variable zvichienderana nechirongwa | $ 10 kana pasi |
| SingleCare mutengo | $ 357 | $ 10 |
Zvakajairika mhedzisiro mhedzisiro yeTrintellix vs. Zoloft
Trintellix naZoloft imwe neimwe inokanganisa nzira dzeserotonin, uye nekudaro yavo mhedzisiro mhedzisiro yakafanana asi inogona kuitika munzvimbo dzakasiyana. Imwe yeaya madhiragi angangokonzeresa gastrointestinal mhedzisiro senge kusvotwa, kurutsa, manyoka, uye / kana kupatira. Nausea inowanikwa mune vakawanda sevatatu muvatatu vanotora Trintellix, uye 1 muvarwere vana vanotora Zoloft.
Zoloft inonzi inokonzera kushushikana mu11% yevarwere vanoitora, nepo Trintellix zvinyorwa zvisingataure kushushikana sekukanganisa mhedzisiro.
Kusagadzikana pabonde kunoita kunge kunoitika padanho repamusoro neTrintellix kana ichienzaniswa neZoloft, 30-35% maringe ne6% zvichiteerana. Zvepabonde mhedzisiro mhedzisiro zvakakosha kufunga sezvo zvingatungamira varwere kuti vasiye mushonga. Hapana zvinodhaka zvinomiririra kukosha kwekurasikirwa kana kuwedzera huremu.
Iyi inotevera rondedzero haina kuitirwa kuti ive izere runyorwa rweakashata zviitiko. Ndokumbirawo ubvunze wemishonga, chiremba, kana mumwe chiremba wezvekurapa kuti uwane yakazara rondedzero yemhedzisiro inogona kuitika.
| Trintellix | Zoloft | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Nausea | Ehe | 32% | Ehe | 26% |
| Muromo wakaoma | Ehe | 8% | Ehe | 14% |
| Kudikitira | Kwete | n / a | Ehe | 7% |
| Manyoka | Ehe | 7% | Ehe | makumi maviri% |
| Kuzvimbirwa | Ehe | 6% | Ehe | 6% |
| Dyspepsia | Kwete | n / a | Ehe | 8% |
| Kusvipa | Ehe | 6% | Ehe | 4% |
| Dzungu | Ehe | 9% | Ehe | 12% |
| Kukotsira | Kwete | n / a | Ehe | gumi neimwe% |
| Zviroto zvisina kujairika | Ehe | 3% | Kwete | n / a |
| Pruritus | Ehe | 3% | Kwete | n / a |
| Kuderedza kudya | Kwete | n / a | Ehe | 3% |
| Kubata ropa | Ehe | 1% | Kwete | n / a |
| Yakadzikira libido | Ehe | 30-35% | Ehe | 6% |
Kwayaka: Trintellix ( Zuva Nezuva Zoloft ( Zuva Nezuva )
Kubatana kwezvinodhaka zveTrintellix vs. Zoloft
Iko kushandiswa panguva imwe chete kweTrintellix kana Zoloft ine monoamine oxidase inhibitors kunogona kutungamira kune yakawedzera chiitiko che serotonin syndrome. Serotonin syndrome inoratidzirwa nekunzwa kushushikana, kutenderera, kana kuve nekuwedzera kwemoyo kana kuwedzerwa kweropa. Izvi zvinoitika kana paine mwero wepamusoro serotonin mumuviri. Mimwe mishonga inogona kutungamira kuserotonin syndrome painoshandiswa neTrintellix kana Zoloft inosanganisira fentanyl, lithium, tramadol, buspirone, uye St. John's Wort.
Zoloft inogona kusangana nemamwe makirasi emishonga uye inokonzeresa mhando yemoyo arrhythmia inozivikanwa seyakareba nguva yeQTc. Izvi zvinogona kuitika nemishonga inowanzo shandiswa seyththyromycin kana gatifloxacin. Izvo zvinogona zvakare kuitika neantipsychotic senge ziprasidone kana chlorpromazine. Izvo zvakakosha kuti wako prescriber azive nezve ako akazara rondedzero yemishonga usati akutsanangure iwe nyowani.
Iyi inotevera rondedzero haina kuitirwa kuti ive izere runyorwa rwekudyidzana zvinodhaka. Zvakanakisisa kubvunza wako mupi kana wemishonga kune yakazara runyorwa.
| Zvinodhaka | Kirasi yemishonga | Trintellix | Zoloft |
| Selegiline Phenelzine Linezolid Isocarboxazid | Monoamine oxidase inhibitors (MAOIs) | Ehe | Ehe |
| Citalopram Escitalopram Fluoxetine Paroxetine | Kusarudza serotonin reuptake inhibitors (SSRIs) | Ehe | Ehe |
| Desvenlafaxine Venlafaxine Duloxetine Levomilnacipran | Kusarudza norepinephrine reuptake inhibitors (SNRIs) | Ehe | Ehe |
| Amitriptyline Desipramine Doxepin Imipramine Nortriptyline | Tricyclic antidepressants | Ehe | Ehe |
| Almotriptan Eletriptan Frovatriptan Naratriptan Rizatriptan Sumatriptan Zolmitriptan | Triptans | Ehe | Ehe |
| Clopidogrel Heparin Warfarin | Platelet inhibitors | Ehe | Ehe |
| Aspirin | Nonsteroidal anti-inflammatory drug (NSAIDs) | Ehe | Ehe |
| Phenytoin | Anti-pfari | Kwete | Ehe |
| Ziprasidone Iloperidone Chlorpromazine Droperidol | Anti-psychotic | Kwete | Ehe |
| Erythromycin Gatifloxacin Moxifloxacin | Mishonga inorwisa mabhakitiriya | Kwete | Ehe |
| Quinidine Procainamide Amiodarone Sotalol | Antiarrhythmics | Kwete | Ehe |
Yambiro yeTrintellix vs. Zoloft
Varwere vane kushushikana kukuru kwekushushikana vanogona kusangana nekuwedzera kwekushushikana kana kuzviuraya pfungwa pamwe kana vasina kurapwa nemishonga yekunyorera seTrintellix kana Zoloft. Zviratidzo izvi zvinogona kuwedzera kusvika kuregererwa kweMDD kwaitika. Trintellix naZoloft zvinogona kutungamira mukuwedzera kuzviuraya muvechidiki uye vechidiki, kunyanya mumatanho ekutanga ekurapwa. Varwere ava vanofanirwa kuongororwa zvakanyanya, uye shanduko yekurapa inogona kudikanwa kana zviratidzo zvitsva zvikamuka kana kuwedzera kuipa.
Izvo zvakakosha kuti urangarire kuti zvinodhaka zvakaita saTrintellix naZoloft hazviunze kuregererwa kwekukurumidza kwezviratidzo. Zvinogona kutora angangoita mavhiki maviri kuti uone chero rudzi rwechiratidzo shanduko, uye kusvika kumavhiki mana kusvika matanhatu kuti uone kuzara kwechirwere. Izvo zvakakosha kuti varwere vanzwisise iyi yakatarwa nguva kuitira kuti varege kukurumidza kurega mushonga nekuda kwekushaya mhedzisiro.
Serotonin syndrome, inokonzerwa neasina kujairika mazinga eserotonin, inogona kuitika naTrintellix naZoloft. Izvo zvinogona kukonzeresa kunzwa kwekushushikana, dzungu, uye zvichitungamira kuwedzerwa kurova kwemoyo.
Trintellix inofanira kushandiswa nekuchenjerera kune varwere vane nhoroondo kana nhoroondo yemhuri yemania, hypomania, kana bipolar kusagadzikana. Trintellix yave ichizivikanwa nekumisikidza mania uye hypomania episiti mune varwere vanoitora kuora mwoyo.
Inowanzo bvunzwa mibvunzo nezve Trintellix vs. Zoloft
Chii chinonzi Trintellix?
Trintellix mushonga unodzvinyirira unoshandiswa pakurapa kushushikana kukuru. Trintellix yakasarudzika mukuti iyo serotonin modulator uye inosimudzira. Trintellix inowanikwa mumapiritsi emuromo mu5 mg, 10 mg, uye 20 mg simba.
Chii chinonzi Zoloft?
Zoloft mushonga unodzvinyirira unoshandiswa pakurapa kushushikana kukuru pamwe nekumwe kushushikana uye kusagadzikana kwepfungwa. Zoloft iri mukirasi yemishonga inozivikanwa sekusarudza serotonin reuptake inhibitors (SSRIs). Zoloft inowanikwa semapiritsi emuromo mu25 mg, 50 mg, uye 100 mg simba, pamwe nekunwa mvura yemumuromo.
Trintellix naZoloft zvakafanana here?
Kunyange vese vari vaviri Trintellix naZoloft vachibata rakakura dambudziko rekushungurudzika nekuwedzera iripo serotonin, vanozviita mune akasiyana mafashoni uye nekudaro haasi iwo mumwe mushonga.
Trintellix kana Zoloft zviri nani here?
Kunyange zvazvo Trintellix neZoloft vari kushivirira zvinodzvinyirira kana zvichienzaniswa nemimwe mishonga, zvimwe zvidzidzo zvekiriniki zvinoratidza kuti Trintellix inogona kunge iri sarudzo yakanakisa yevarwere vakatokundikana kurapwa neSSRIs senge Zoloft.
Ndinogona here kushandisa Trintellix kana Zoloft ndichiri nepamuviri?
Chikafu neDrug Administration (FDA) inofunga zvese zviri zviviri Trintellix uye Zoloft nhumbu yechikamu C, zvichireva kuti pakange pasina zvakakwana zvidzidzo zvevanhu kuona kuchengetedzeka. Kazhinji, chero chinodhaka chinofanira kungoshandiswa chete nerubatsiro kuna amai zvakajeka zvinopfuura njodzi kumucheche.
Ndinogona here kushandisa Trintellix kana Zoloft nedoro?
Doro rinogona kuwedzera huturu hwezvinhu zviviri Trintellix uye Zoloft. Kunwa doro uchinwa mishonga iyi kunogona kukonzera kukanganisika kwepfungwa, uye nekuda kwechikonzero ichi, varwere vanorayirwa kuti vadzivise doro kana vakatora mumwe wemishonga iyi.
Trintellix inobatsira kunetseka here?
Trintellix haina kuratidzwa kurapa chero rudzi rwekushushikana kusagadzikana.
Trintellix inosiyana sei nedzimwe SSRIs?
Trintellix zvese serotonin modulator uye inosimudzira. Aya zviito zvinoshanda kugadzira yakawanda yemahara serotonin inotungamira kune zvirinani mamood uye mashoma ekuora mwoyo zviratidzo.
