Tramadol vs. Hydrocodone: Misiyano, kufanana, uye ndeipi iri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Tramadol uye hydrocodone mishonga miviri inoshandiswa kurapa marwadzo asiri nyore kurerutswa neasina opioid analgesic. Ose ari maviri mishonga anogona kurapa zvine mwero kusvika pakurwadziwa kwakanyanya mushure mekuvhiyiwa kana mune zvisingaperi mamiriro senge kenza. Zvisinei, kune dzakawanda zviitiko zvekurwadziwa, isiri-opioid kurapa inowanzoedzwa kutanga.
Ese maviri tramado l uye hydrocodone anoshanda nekusunga kune mu opioid receptors kuti achinje maitiro anoita munhu marwadzo. Semishonga yekunyorera maopioid, iwo ane simba zvakanyanya kupfuura ako epakati pamusoro-e-e-pari kurwadziwa marwadzo. Naizvozvo, iyi mishonga inoda kushanyirwa nachiremba kuti uone marwadzo ako.
Ndeupi mutsauko mukuru pakati peTramadol neHydrocodone?
Tramadol izita rakajairika reUltram, Ultram ER, uye ConZip. Iyo Chirongwa IV narcotic zvinoenderana neDEA zvinoreva kuti ine imwe mikana yekushungurudzwa. Ipo ichisunga mu mu opioid receptors, inogona zvakare kuwedzera chiitiko cheimwe huropi maurotransmitter senge norepinephrine uye serotonin.
Hydrocodone izita rakajairika reZohydro ER uye Hysingla ER. Hydrocodone inotorwawo semubatanidzwa piritsi neacetaminophen pasi pemazita ezita Vicodin kana Lortab. Kusiyana ne tramadol, hydrocodone iShedhiyo II DEA inodzorwa mishonga ine njodzi huru yekushungurudzwa.
| Misiyano mikuru pakati peTramadol neHydrocodone | ||
|---|---|---|
| Tramadol | Hydrocodone | |
| Kirasi yemishonga | Opioid | Opioid |
| Brand / generic chinzvimbo | Shanduro yeGeneric inowanikwa | Shanduro yeGeneric inowanikwa |
| Chii chinonzi generic zita? Chii chinonzi zita rechiratidzo? | Generic: Tramadol Mutengo: Ultram, Ultram ER | Generic: Hydrocodone Mutengo: Zohydro ER, Hysingla ER, Vicodin (inosanganiswa neacetaminophen), Lortab (inosanganiswa neacetaminophen), Norco (inosanganiswa neacetaminophen) |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa remuromo Oral piritsi, yakawedzerwa-kusunungurwa Oral capsules Kumiswa kwemuromo | Hwendefa remuromo Oral piritsi, yakawedzerwa-kusunungurwa Oral capsules Oral solution |
| Ndeipi muyero wakajairwa? | Ultram: 50 kusvika 100 mg maawa mana kusvika matanhatu sezvaanodiwa Ultram ER: 100 mg maawa makumi maviri nemasere | Zohydro ER: 10 mg maawa gumi nemaviri ese Hysingla ER: 20 mg maawa makumi maviri nemana Vicodin, Lortab, Norco (inosanganiswa neacetaminophen): 5 kusvika 10 mg maawa mana kusvika matanhatu sezvaanodiwa |
| Yakareba sei iyo yekurapa? | Mazuva ese sezvazvinodiwa. Nguva yekurapa inoenderana nemirairo yechiremba wako. | Mazuva ese sezvazvinodiwa. Nguva yekurapa inoenderana nemirairo yechiremba wako. |
| Ndiani anowanzoshandisa mushonga? | Vakuru vane makore gumi nemasere zvichikwira | Vakuru vane makore gumi nemasere zvichikwira |
Mamiriro ezvinhu akarapwa neTramadol uye Hydrocodone
Tramadol uye hydrocodone zvese zvinoratidzwa kwekutambudzika kwekutambudzika. Ivo vanowanzo gadzirirwa kana iwe uine zvine mwero kusvika kwakakomba kurwadziwa kusingaperi, kunyanya kubva kumamiriro akadai sekenza. Mishonga iyi miviri inowanzo shandiswa pakurwadziwa mushure mekukuvara nekuvhiyiwa.
| Mamiriro | Tramadol | Hydrocodone |
| Pakati nepakati kusvika pakurwadziwa kwakanyanya | Ehe | Ehe |
| Kurwara kusingaperi | Ehe | Ehe |
| Marwadzo kubva mukukuvara kana mushure mekuvhiyiwa | Ehe | Ehe |
| Kanzera kurwadziwa | Ehe | Ehe |
Ko Tramadol kana Hydrocodone inoshanda zvakanyanya here?
Tramadol uye hydrocodone ese ari maviri anoshanda anonyorwa opioid ekurwadziwa. Kune zvidzidzo zvakati wandei zvichienzanisa kugona kwazvo. Nekuti hydrocodone iShedhiyo II opiate, inogona kutariswa seine simba kunyangwe ichiuya iine mukana wepamusoro wekushungurudzwa. Tramadol inogona kunge iine mukana wakaderera wekushungurudza pamwe nemhedzisiro yakaipa.
Mune imwe kudzidza kwakawanda , tramadol ine acetaminophen yakafananidzwa nehydrocodone ine acetaminophen kune varwere vane marwadzo kubva kumakumbo emakumbo. Vakakomberedza mazana mana evarwere vakapatsanurwa kuita mapoka maviri vachigamuchira mumwe mushonga kana mumwe. Mhedzisiro yakawana kuti ese ari maviri mishonga anopa akafanana marwadzo ekurwadziwa mukati maawa mana maringe ne placebo.
Mune imwe kliniki kuyedzwa , hydrocodone ine acetaminophen yakafananidzwa ne tramadol mu68 varwere. Varwere ava vaive vasvika padhipatimendi rekukurumidzira remaronda musculoskeletal mumajoini, mapfupa, kana mhasuru. Mhedzisiro yakawana kuti hydrocodone ine acetaminophen inopa zororo rekurwadziwa kana ichienzaniswa netramadol inoenderana nemarwadzo ezviyero zvine chiyero cheanalogog (VAS).
Mune kaviri-bofu kuyedzwa , hydrocodone ine acetaminophen yakafananidzwa ne tramadol mu118 varwere vane kurwadziwa kusingaperi kubva kugomarara. Tramadol yakaratidza kuzorora kwekurwadziwa mu62% yevarwere zvichienzaniswa ne56.5% yevarwere vane hydrocodone. Zvisinei, kusununguka kwekutambudzika kwakafanana mumapoka maviri aya. Tramadol yakawanikwa zvakare ichiburitsa yakaipa mhedzisiro maringe nehydrocodone.
Kunyangwe iwe wakatemerwa tramadol kana hydrocodone inotsamira zvakanyanya padanho remarwadzo ako. Paunenge uchitarisa marwadzo ako, chiremba wako achatarisa nhoroondo yako yakazara yekurapa, chero nhoroondo yekushandisa zvinodhaka, uye chero mishonga inogona kukonzera kusangana kwemishonga. Naizvozvo, mishonga yekurwadziwa yakasarudzika zvakanyanya uye inoda kubvunza kwachiremba kuti uone kuti ndezvipi zvinonyanya kushanda kwauri.
Kufukidza uye kuenzanisa kwemutengo weTramadol vs. Hydrocodone
Tramadol inowanikwa seyakajairika mushonga. Iyo inowanzo kufukidzwa neMedare uye mazhinji zvirongwa zveinishuwarenzi. Ivhareji mutengo wekuwanikwa kwemakumi matanhatu emakumi mashanu emadhigiramu e-tramadol ari madhora makumi mana. Iwe unochengetedza zvakawanda neSingleCare koponi ye generic tramadol kukomisheni yemunharaunda yako.
Hydrocodone mushonga unowanzoitika unowanzo kuvharwa neMedare uye mazhinji zvirongwa zveinishuwarenzi. Mutengo wehydrocodone unosiyana pakati pezvirongwa zveinishuwarenzi zvakasiyana. Norco iyo ine hydrocodone uye acetaminophen inogona kumhanya pamutengo wepakati we $ 317. Uine CouponCare koponi, unogona kutarisira kuchengetedza zvimwe pane mushonga wehydrocodone ine acetaminophen.
| Tramadol | Hydrocodone | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare? | Ehe | Ehe |
| Standard muyero | 50 mg mapiritsi (kupihwa makumi matanhatu) Zvinoenderana nezvakanyorwa nachiremba wako | 5-325 mg mapiritsi (kupihwa zana) Zvinoenderana nezvakanyorwa nachiremba wako |
| Chaizvoizvo Medicare copay | $ 40 | $ 317 |
| SingleCare mutengo | $ 15 | $ 18 |
Zvakajairika mhedzisiro mhedzisiro yeTramadol uye Hydrocodone
Tramadol uye hydrocodone zvinogona kukonzeresa mhedzisiro. Nekuti zvese zviri zviviri zvinokanganisa iyo yepakati tsinga system (CNS), ivo vese vanogona kukonzera dzungu, kurara, uye kuneta. Iyi mishonga inogona zvakare kukonzera gastrointestinal mhedzisiro mhedzisiro sekuzvimbirwa kana kurwadziwa nemudumbu. Nausea, kurutsa, kuoma muromo, uye kutemwa nemusoro mimwe mhedzisiro yakagovaniswa.
Tramadol inogona zvakare kukonzera manyoka, kuzvimba, uye kudikitira mune vamwe vanhu. Kune rimwe divi, hydrocodone inogona zvakare kukonzera fluid buildup (edema) kana mhasuru spasms mune vamwe vanhu. Pakazara, zvinowanzoitika mhedzisiro zvinogona kusangana pakati pemishonga iyi miviri sezvo vari mukirasi imwechete.
Zvimwe zvisingawanzo asi zvakakomba mhedzisiro ye tramadol uye hydrocodone inogona kusanganisira kushushikana, kushushikana, kana kumwe kukanganisa kwepfungwa. Allergic reaction inokwanisika uye inogona kusanganisira kuputika, kupwanya, uye kurwadziwa pachipfuva.
| Tramadol | Hydrocodone | |||
| Side Migumisiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kuzvimbirwa | Ehe | 24-46% | Ehe | gumi neimwe% |
| Dzungu | Ehe | 26-33% | Ehe | 3% |
| Nausea | Ehe | 24-40% | Ehe | 10% |
| Kutemwa nemusoro | Ehe | 18-32% | Ehe | 4% |
| Kukotsira | Ehe | 16-25% | Ehe | 5% |
| Kusvipa | Ehe | 9-17% | Ehe | 3% |
| Kuchenesa (Pruritus) | Ehe | 8-11% | Ehe | 3% |
| Kushaya simba | Ehe | 6-12% | Ehe | 4% |
| Kudikitira | Ehe | 6-9% | Kwete | - |
| Kuzvidya mwoyo | Ehe | 5-13% | Kwete | - |
| Muromo wakaoma | Ehe | 5-10% | Ehe | 3% |
| Manyoka | Ehe | 5-10% | Kwete | - |
| Edema | Kwete | - | Ehe | 1% |
| Kufema utachiona | Kwete | - | Ehe | 1% |
| Tsandanyama mhasuru | Kwete | - | Ehe | 1% |
| Kutambudzika shure | Kwete | - | Ehe | 1% |
* Bvunza chiremba kana wemishonga kune zvese zvinokanganisa mhedzisiro.
Kunobva: Mazuva ese (Tramadol HCl) , Zuva Nezuva (Zohydro ER) .
Kubatana kwezvinodhaka zveTramadol vs. Hydrocodone
Tramadol uye hydrocodone zvine kudyidzana kwakafanana nemamwe madhiragi. Nekuti ivo vanogadziriswa muchiropa, vanowanzo batana nemimwe mishonga inobata maenzymes echiropa.
Mishonga inodzivisa CYP3A4 uye CYP2D6 enzyme yechiropa inosanganisira erythromycin, ketoconazole, uye ritonavir iyo inogona kuwedzera mwero wemaopioid mumuviri uye kuwedzera njodzi yemhedzisiro. Zvinodhaka zvinokonzeresa CYP3A4 enzymes echiropa anosanganisira carbamazepine uye phenytoin iyo inogona kudzikisa huwandu hweopioid mumuviri uye kudzikisira kushanda kwayo.
Tramadol uye hydrocodone inogona zvakare kudyidzana nemamwe madhiragi ane CNS mhedzisiro. Aya marudzi emishonga anosanganisira antidepressants, anticonvulsants, benzodiazepines, mhasuru relaxers, uye zvimwe zvakawanda. Kutora maopioid nemishonga yekudzvinyirira iyo inowedzera serotonin inogona kuwedzera njodzi yeserotonin syndrome, mamiriro akakomba anoda kurapwa kwenjodzi.
Sekureva kweiyo FDA drug label, tramadol inogona zvakare kusangana ne digoxin uye warfarin. Mishumo yakawana zvisingawanzo zviitiko zve digoxin chepfu uye zvakachinja warfarin mhedzisiro. Iyo FDA label yehydrocodone inotaura zvakare kuti laxatives yakasimba inogona kudzora mhedzisiro yehydrocodone mumuviri.
Hazvikurudzirwi kunwa doro uchishandisa opioid. Doro rinogona kusanganisa mhedzisiro yemopioid yakadai sekukotsira uye dzungu.
| Zvinodhaka | Kirasi Yezvinodhaka | Tramadol | Hydrocodone |
| Erythromycin Clarithromycin Telithromycin Rifampin | Mishonga inorwisa mabhakitiriya | Ehe | Ehe |
| Ketoconazole Itraconazole | Antifungal mumiriri | Ehe | Ehe |
| Ritonavir Atazanavir Darunavir Indinavir Lopinavir Saquinavir | Protease inhibitor | Ehe | Ehe |
| Phenytoin Carbamazepine | Anticonvulsant | Ehe | Ehe |
| Escitalopram Fluoxetine Paroxetine Sertraline Citalopram | Kusarudza serotonin reuptake inhibitor (SSRI) antidepressant | Ehe | Ehe |
| Venlafaxine Milnacipran Duloxetine Desvenlafaxine | Serotonin-norepinephrine reuptake inhibitor (SSNRI) inodzvinyirira | Ehe | Ehe |
| Doxepin Amitriptyline Clomipramine Desipramine Imipramine Nortriptyline | TCA inodzvinyirira | Ehe | Ehe |
| Naratriptan Rizatriptan Sumatriptan Zolmitriptan | Triptan | Ehe | Ehe |
| Alprazolam Clonazepam Diazepam Lorazepam | Benzodiazepine | Ehe | Ehe |
| Rasagiline Isocarboxazid Phenelzine Selegiline Tranylcypromine | Monoamine oxidase inhibitor (MAOI) | Ehe | Ehe |
| Cyclobenzaprine Metaxalone | Tsvina inozorodza | Ehe | Ehe |
| Lactulose | Laxative yakasimba | Kwete | Ehe |
| Digoxin | Cardiac glycoside | Ehe | Kwete |
| Warfarin | Anticoagulant | Ehe | Kwete |
* Iri rinogona kunge risiri runyorwa ruzere rweese mukana wekupindirana kwezvinodhaka. Bvunza chiremba nemishonga yose yaungave uri kutora.
Yambiro yeTramadol uye Hydrocodone
Tramadol uye hydrocodone zvinotakura yambiro yekupindwa muropa nekushungurudzwa kana zvisina kushandiswa sekurairwa. Kupindwa muropa kunogona kutungamira mukutsamira panyama izvo zvinogona kukonzeresa kubvisa zviratidzo kana mushonga ukamiswa chero chikonzero. Kurega zviratidzo zvinogona kusanganisira kushushikana, kushaya hope, uye kusagadzikana.
Kutora zvinopfuura chiyero chakatemwa cheopioid kunogona kuwedzera njodzi yekuwedzeredza, coma, uye kufa. Hupenyu-hunotyisidzira mhedzisiro senge yakanyanya kufema kufema kushushikana uye kugona kugona kunogona kuitika nekuwedzeredza. Neichi chikonzero, maopioid haakurudzirwe muvana nekuda kwekuwedzera kwenjodzi ye matambudziko ekufema uye kufa .
Hazvikurudzirwi kunwa doro kana kutora mamwe maCS zvinodhaka nemaopioid. Izvi zvinodaro nekuti vanowedzera njodzi ye CNS mhedzisiro senge sedation, kunonoka kufema, coma, uye kufa. Kunyangwe paine imwe data inodiwa, nyowani tsvagiridzo inoratidza kuti tramadol inogona kuve nenjodzi yakakwira yekufa kwese ichienzaniswa nemishonga inorwisa-kupisa.
Ese maviri tramadol uye hydrocodone ari muchikamu chepamuviri C. Naizvozvo, ivo havawanzokurudzirwa kuvakadzi vane nhumbu kana kuyamwisa nekuda kwenjodzi yekukuvadza mwana asati azvarwa. Tsvaga mazano ekurapa kana iwe uri nepamuviri kana kuronga nhumbu.
Inowanzo bvunzwa mibvunzo nezve Tramadol vs. Hydrocodone
Chii chinonzi tramadol?
Tramadol mushonga weopioid unoshandiswa kurapa zvine mwero kusvika pakurwadziwa kwakanyanya. Iyo Chirongwa IV chinodhaka chinoda mushonga uye kuongororwa kwekurwadziwa nachiremba. Inowanikwa mune yekukurumidza-kuburitsa uye yakawedzerwa-kuburitsa fomu zvichienderana nekurwadziwa kuomarara.
Chii chinonzi hydrocodone?
Hydrocodone imishonga yeopioid iyo inogona kubata zvine mwero kusvika pakurwadziwa kwakanyanya. Iyo Chirongwa II chinodhaka chinogona kuve nemukana wakakura wekushungurudzwa uye kuvimba. Inowanikwa mune yakawedzeredzwa-kuburitsa fomu pamwe nekubatanidza piritsi ine acetaminophen.
Ko tramadol uye hydrocodone zvakafanana here?
Kunyangwe ese ari maviri maopioid, tramadol uye hydrocodone hazvina kufanana. Ivo vane zvakafanana zvinoshandiswa zvinoenderana nekurwadziwa kwauri kuita. Asi ivo vanouyawo nenzira dzakasiyana siyana uye vane mimwe mhedzisiro uye kusangana kwemishonga.
Ko tramadol kana hydrocodone zvirinani here?
Zvidzidzo zvinoratidza kuti tramadol uye hydrocodone zvese zviri zviviri zvichienzaniswa zvinoshanda pakurwadziwa. Mimwe mishumo inoratidza kuti tramadol ine yakaipa mhedzisiro mhedzisiro kana ichienzaniswa nehydrocodone. Nekudaro, zvimwe zvidzidzo zvinoratidza kuti hydrocodone ine simba uye inogadzira zororo rakawanda kune vamwe vanhu.
Ko tramadol yakasimba kudarika codeine here?
Ose tramadol uye codeine anogona kubvisa marwadzo uye ese ari maviri anoonekwa seasina opioid. Nekudaro, ivo vanogona kusiyanisa mune yavo mhedzisiro mhedzisiro uye mashandisiro. Kusiyana ne tramadol, codeine inogona zvakare kushandiswa seyekudzvinyirira kukosora.
Ko tramadol opiate here?
Ehe. Tramadol ndeye opiate narcotic. Iyo yakagadzirwa uye iri mukirasi imwechete yemishonga seimwe marwadzo eopioid anodzora. SeShedhiyo IV chinodhaka, ine zvishoma mukana wekushungurudzwa uye kuvimba uchienzaniswa nemamwe maopioid.
Iko hydrocodone opioid here?
Ehe. Hydrocodone opioid. Iyo semi-synthetic opioid ine mhedzisiro yakafanana kune mamwe maopioid echisikigo senge morphine kana kodhiine.
