Losartan vs. lisinopril: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Kana iwe uri mumwe wemamirioni 103 emamerica ane BP , chiremba wako anogona kunge akataura nezvako kutanga iwe pamushonga kudzikisa yako BP. Losartan uye lisinopril ese ari maviri mishonga inonyorwa yemishonga inoshandiswa kurapa BP. neBP ). Losartan ndeye angiotensin II receptor blocker (ARB) uye lisinopril angiotensin-inoshandura enzyme inhibitor (ACE inhibitor).
Mishonga iyi yese inoshanda pachikamu chemuviri chinonzi renin-angiotensin system asi nenzira dzakasiyana. Mune renin-angiotensin system, ACE inhibitors inovhara chinhu chinonzi angiotensin II kubva pakugadzirwa. Angiotensin II inoderedza mitsipa yeropa uye inowedzera kuwedzera kweropa, saka nekuvhara kugadzirwa kweangiotensin II, BP inoderedzwa. MaARB anovharira angiotensin II kubva pakusunga kune zvinogamuchirwa, zvichideredza BP.
Ndeapi misiyano mikuru pakati peLosartan uye lisinopril?
Losartan iARB, inowanikwa muzita rezita uye fomu yepiritsi, seCozaar (kana Hyzaar painosanganiswa nehydrochlorothiazide, diuretic inowanzo pfupikiswa seHCTZ). Iyo yakajairwa dosi inotangira kubva 25 mg kusvika 100 mg zuva nezuva.
Lisinopril iCE inhibitor inowanikwa mutafura fomu nemazita ezita Prinivil kana Zestril (kana Zestoretic kana yakabatana neHCTZ). Iyo inowanikwawo semhinduro yemumuromo inonzi Qbrelis. Iyo yakajairwa dosi inotangira kubva ku5 mg kusvika ku40 mg zuva nezuva.
RELATED: Losartan ruzivo | Lisinopril ruzivo
| Misiyano mikuru pakati pe losartan uye lisinopril | ||
|---|---|---|
| Losartan | Lisinopril | |
| Kirasi yemishonga | Angiotensin receptor blocker (ARB) | ACE inhibitor |
| Brand / generic chinzvimbo | Brand uye generic | Brand uye generic |
| Chii chinonzi zita rechiratidzo? | Cozaar Hyzaar (losartan / HCTZ) | Prinivil Zestril Qbrelis (wemuromo mhinduro) Zestoretic (lisinopril / HCTZ) |
| Ndeapi mafomu (s) ayo mushonga unouya? | Piritsi (roga uye rakabatana neHCTZ) | Piritsi (roga uye rakabatana neHCTZ) |
| Ndeipi muyero wakajairwa? | 25 kusvika 100 mg zuva nezuva | 5 kusvika 40 mg zuva nezuva |
| Inguva yakareba sei kurapwa kwacho? | Nguva refu | Nguva refu |
| Ndiani anowanzoshandisa mushonga? | Vakuru, vana (zvinoenderana nechiratidzo) | Vakuru, vana (zvinoenderana nechiratidzo) |
Unoda mutengo wakanakisa pasisinopril?
Saina ma lisinopril mutengo wekuzivisa uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu anorapwa na losartan vs. lisinopril
Losartan inoratidzirwa kurapwa kwehypertension (HTN), kana kuwedzerwa kweropa. Inoshandiswa zvakare kudzikisa njodzi yekurohwa nevarwere vane yakakwira BP uye kuruboshwe ventricular hypertrophy, uye inoshandiswawo kurapa chirwere cheshuga nephropathy mune vamwe varwere.
Lisinopril inoratidzirwa pakurapa kweHTN, sechirevo chekurapa mu congestive moyo kutadza, uye kugadzirisa kupona mushure mekurwadziwa kwemoyo.
Ose mairi madhiragi anewo asiri-ekushandisa mashandisirwo, akatsanangurwa pazasi.
| Mamiriro | Losartan | Lisinopril |
| Kurapa kwehypertension (HTN) | Ehe | Ehe |
| Deredza njodzi yekurohwa nevarwere vaneHTN uye kuruboshwe ventricular hypertrophy (LVH) | Ehe | Kunze-chitaridzi |
| Kurapa kweshuga nephropathy ine yakakwira serum creatinine uye proteinuria mune varwere vane mhando 2 chirwere cheshuga uye nhoroondo yeHTN | Ehe | Kunze-chitaridzi |
| Adjunctive kurapwa mune manejimendi yemoyo kukundikana mune varwere vasiri kupindura zvakakwana kune diuretics uye digitalis | Kunze-chitaridzi | Ehe |
| Kurapa kwevarwere vane hemodynamically vakagadzikana mukati memaawa makumi maviri nemana eacute myocardial infarction (MI) kugadzirisa kupona | Kunze-chitaridzi | Ehe |
| Kukundikana kwemoyo nechikamu chiduku cheejection | Kunze-chitaridzi | Kunze-chitaridzi |
| Marfan syndrome kudzikisa chiyero cheaortic dilatation | Kunze-chitaridzi | Kunze-chitaridzi |
| Manejimendi yevarwere vane isiri-ST-kukwirira kwakanyanya coronary syndrome | Kunze-chitaridzi | Kunze-chitaridzi |
| Itsvo kuisira vanogamuchira | Kunze-chitaridzi | Off-label (mune varwere vane post-transplant erythrocytosis) |
| Varwere vane proteinuric chisingaperi itsvo chirwere | Kunze-chitambi (mune vane chirwere cheshuga) | Kunze-chitambi (mune chirwere cheshuga kana nondiabetic varwere) |
| Yakagadzikana coronary artery chirwere | Kunze-chitaridzi | Kunze-chitaridzi |
Is losartan kana lisinopril inoshanda zvakanyanya?
Muongororo yezvidzidzo makumi matanhatu neshanu tichienzanisa maARB (kusanganisira losartan) neACE inhibitors (kusanganisira lisinopril), ese mapoka emishonga akawanikwa aine zvakafanana mhedzisiro yenguva refu paBP. Vanyori vakapedzisawo kuti ese makirasi emishonga ane mhedzisiro yakaenzana pakufa, zviitiko zvemoyo, zviitiko zvakakomba zvakashata, hupenyu hwehupenyu, uye zvinhu zvine njodzi zvakaita seepidid mazinga, chirwere cheshuga mellitus, uye akasiya ventricular mashoma uye mashandiro.
Mune diki kudzidza yevarwere vane chirwere cheitsvo, losartan uye lisinopril vakave nemhedzisiro yakafanana pabasa reitsvo uye kuwedzerwa kweropa.
Mushonga unoshanda kwazvo kwauri unofanirwa kusarudzwa nachiremba wako, uyo anogona kutarisa pamufananidzo uzere wehutano hwako (s), nhoroondo, uye mimwe mishonga yauri kutora.
Kuvhavha uye mutengo kuenzanisa kwe losartan vs. lisinopril
Ose losartan uye lisinopril akafukidzwa neinishuwarenzi uye Medicare Chikamu D mune generic fomu. Iwo marita ezita ezita anogona kuvharwa pane yakakwira copay. Kunze kwehomwe mutengo wemapiritsi makumi matatu esolartan 100 mg inogona kubva pamadhora makumi maviri nemasere- $ 70, uye iyo Medicare Chikamu D copay ingangoita madhora 0- $ 13. Iine CouponCare koponi, mutengo wemitengo iri $ 9- $ 16 zvinoenderana nekamesi iri kutora chikamu. Kunze kwehomwe mutengo wemapiritsi makumi matatu e10 mg lisinopril ingangoita madhora gumi neshanu, uye iyo Medicare Chikamu D copay ingangoita $ 0- $ 7. Iwe unogona kusevha mari pane lisinopril nekushandisa iyo ImweCare dhisikaundi kadhi kana coupon.
Edza kadhi reSpecialCare rekutora kadhi
| Losartan | Lisinopril | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare? | Ehe | Ehe |
| Standard muyero | # 90, 100 mg mahwendefa | # 90, 20 mg mahwendefa |
| Chaizvoizvo Medicare copay | $ 0- $ 13 | $ 0- $ 7 |
| SingleCare mutengo | $ 28- $ 70 | $ 9- $ 26 |
Zvakajairika mhedzisiro mhedzisiro yelosartan vs. lisinopril
Mhedzisiro inowanzoitika ye losartan inosanganisira kukosora, dzungu, chirwere chepamusoro chekufema, kuneta, uye manyoka.
Mhedzisiro inowanzoitika yelisinopril inosanganisira kukosora, dzungu, kurwadziwa nemusoro, kupera simba uye manyoka.
Mimwe mhedzisiro inogona kuitika. Bvunza nyanzvi yezvehutano kuti uwane yakazara rondedzero yemhedzisiro.
| Losartan | Lisinopril | |||
| Side Migumisiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kukosora | Ehe | 17-29% | Ehe | 3.5-69% |
| Dzungu | Ehe | 3% | Ehe | 5.4% |
| Kumusoro kufema hutachiona | Ehe | 8% | Ehe | 2.1% |
| Kuzara kwemhino | Ehe | piri% | Ehe | 0.4% |
| Kutambudzika shure | Ehe | piri% | Kwete | - |
| Kuneta | Ehe | > 4% | Ehe | 2.5% |
| Manyoka | Ehe | > 4% | Ehe | 2.7% |
| Nausea | Ehe | Hazvina kutaurwa | Ehe | piri% |
| Kutemwa nemusoro | Ehe | Hazvina kutaurwa | Ehe | 5.7% |
Kwayaka: DailyMed (losartan) , Zuva Nezuva (lisinopril)
Kubatana kwezvinodhaka zve losartan vs. lisinopril
Losartan kana lisinopril haifanire kushandiswa ne potassium kana mimwe mishonga inowedzera potasium (senge potassium-sparing diuretics), nekuda kwenjodzi yehyperkalemia. Pamusoro pezvo, bvunza chiremba wako nezve potasium mukudya kwako uye kana iwe uchifanira kudzivirira potassium-zvakapfuma zvekudya uye zvinotsiva munyu zvine potasium.
NSAIDs (nonsteroidal anti-inflammatory drug) haifanire kushandiswa musanganiswa ne losartan kana lisinopril, nekuti mubatanidzwa unogona kukonzera kukuvara kweitsvo kana kukundikana kweitsvo.
Losartan kana lisinopril haifanire kushandiswa musanganiswa neimwe ACE inhibitor, ARB, kana Tekturna (aliskiren) nekuti mubatanidzwa unowedzera njodzi yekuderera kweropa, potasium yakakwira, kupera simba, kukuvara kweitsvo, kana itsvo kutadza.
Bvunza wako mupi wezvehutano kuti uwane izere runyorwa rwekudyidzana kwezvinodhaka.
| Zvinodhaka | Kirasi Yezvinodhaka | Losartan | Lisinopril |
| Potassium | Electrolyte | Ehe | Ehe |
| Midamor (amiloride) Aldactone (spironolactone) Dyrenium (triamterene) Inspra (eplerenone) | Potassium-inodzivirira diuretics | Ehe | Ehe |
| Aspirin Motrin, Advil (ibuprofen) Aleve (naproxen) Mobic (meloxicam) Celebrex (celecoxib) Relafen (nabumetone) | NSAIDs | Ehe | Ehe |
| Vasotec (enalapril) Lotensin (benazepril) Kuwedzera (quinapril) Altace (ramipril) | ACE inhibitors | Ehe | Ehe |
| Diovan (valsartan) Edarbi Kurwisa (candesartan) Avapro (irbesartan) Micardis (telmisartan) Benicar (olmesartan) | MaARB | Ehe | Ehe |
| Tekturna (aliskiren) | Renin inhibitor | Ehe | Ehe |
| Lithium | Antimanic mumiriri | Ehe | Ehe |
Yambiro dze losartan uye lisinopril
Losartan uye lisinopril vese vanouya neyebhokisi yambiro, inova yambiro yakasimba sekudiwa neDFA. Zvinodhaka (senge losartan uye lisinopril) zvinoshanda pa renin-angiotensin system zvinogona kukonzera kukuvara kwakanyanya kwemucheche / kuremara kwekuberekwa kana kufa uye zvinofanirwa kumiswa kana nhumbu yagadziriswa.
Dzimwe yambiro dzinoshanda kune losartan uye lisinopril:
- Varwere vakashayiwa mvura kana kutora diuretics vanogona kukura yakaderera BP (hypotension).
- Shanduko mune renal basa, kusanganisira zvakanyanya renal kutadza, zvinogona kuitika. Njodzi yacho yakakwira kune varwere vane matambudziko eitsvo kana kukundikana kwakanyanya kwemoyo. Varwere ava vanogona kunge vasiri mukwikwidzi weACE inhibitor kana ARB. Kana mumwe wemishonga iyi ukatanga, basa reitsvo rinofanira kuongororwa.
- Potassium mazinga anofanira kuongororwa.
Lisinopril ine yambiro yekuwedzera:
- Iko kune mukana weanaphylactic reaction (yakaoma allergic reaction), kusanganisira angioedema (kuzvimba) kwechiso, magumo, miromo, rurimi, glottis, uye / kana larynx. Izvi zvinogona kuitika chero nguva panguva yekurapa. Angioedema inosangana ne laryngeal edema inogona kuuraya. Iko kune kubatanidzwa kwerurimi, glottis kana larynx, ingangoita kukanganiswa kwemhepo, kurapwa kwechimbichimbi kunokosha. Lisinopril inofanira kumiswa kana izvi zvikaitika.
- Pane njodzi diki yezvinetso zveropa; chiropa enzymes chinofanira kuongororwa.
- Nekuda kwekuparara kwechinhu chinonzi bradykinin, chikosoro chakaoma chinogona kuitika. Kamwe mushonga ukamiswa, kukosora kunofanira kuenda.
Inowanzo bvunzwa mibvunzo nezve losartan uye lisinopril
Chii chinonzi losartan?
Losartan ndeye angiotensin receptor blocker iyo inobatsira kudzikisa BP. Iyo inogona zvakare kushandiswa kune mamwe akasiyana mamiriro, akatsanangurwa pamusoro.
Chii chinonzi lisinopril?
Lisinopril ndeyeACE inhibitor iyo inobatsira kudzikisa BP. Iyo inoshandiswawo kune mamwe mamiriro ekurapa, akatsanangurwa pamusoro.
Losartan vs. lisinopril zvakafanana here?
Kunyangwe ese ari maviri mishonga anoshanda pane renin-angiotensin system, anoshanda munzvimbo dzakasiyana dzehurongwa, asi ese ari maviri mishonga anoderedza BP uye anoshandiswa kune mamwe moyo kana itsvo mamiriro. Ivo zvakare vane mimwe misiyano mune dosing, yambiro, uye mutengo.
Zvimwe zvakajairika ACE inhibitors (senge lisinopril) ungangodaro wakanzwa nezvazvo zvinosanganisira Lotensin (benazepril), Vasotec (enalapril), Accupril (quinapril), uye Altace (ramipril).
Mamwe maARB (senge losartan) ungangodaro wakanzwa nezvawo anosanganisira Edarbi (azilsartan - hapana generic inowanikwa), Atacand (candesartan), Avapro (irbesartan), Micardis (telmisartan), Diovan (valsartan), uye Benicar (olmesartan).
Is losartan kana lisinopril zvirinani?
Zvidzidzo zvakaratidza maARB senge losartan uye ACE inhibitors senge lisinopril kuva nemhedzisiro yakafanana. Bvunza wako mupi wezvehutano kuti uone kana mumwe wemishonga iyi wakakodzera iwe.
Ndinogona here kushandisa losartan kana lisinopril ndichiri nepamuviri?
Losartan kana lisinopril haifanirwe kutorwa uchiri nepamuviri. Zvese zvinodhaka zvine njodzi kumwana ari kukura uye zvinogona kukonzera kuremara kwakakomba kwekuberekwa kana kutofa kurufu. Kana iwe uri kutotora losartan kana lisinopril uye uone kuti iwe une nhumbu, bvunza chiremba wako nekukurumidza.
Ndinogona here kushandisa losartan kana lisinopril nedoro?
Kunwa doro uchitora losartan kana lisinopril kunogona kuwedzera dzungu, kana kukanganisa ropa rako kana zvimwe zvehutano. Bvunza chiremba wako nezve kushandiswa kwedoro ne losartan kana lisinopril.
Ndinofanira kutora lisinopril uye losartan pamwechete here?
Kwete. Kunyange hazvo mimwe mishonga yekumanikidza kweropa ichishandiswa pamwe chete (senge losartan kana lisinopril pamwe chete nedhiureti), lisinopril uye losartan havafanirwe kutorwa pamwechete. Kuita izvi kunowedzera njodzi yekudzikira kweropa, potasium yakakwira, uye kukuvara kune itsvo, izvo zvinogona kuve zvakakomba kana kutouraya.
Is losartan iACE inhibitor kana beta blocker?
Losartan ndeye angiotensin receptor blocker. Haisi iyo ACE inhibitor kana beta blocker.
Ko losartan inokonzeresa mhedzisiro pane lisinopril?
Zvese zvinodhaka zvine mhedzisiro, kunyangwe lisinopril inowanzo kukonzera kukosora kwakaoma uye ine njodzi yeangioedema (yakakomba yeergizia reaction). Bvunza nyanzvi yezvehutano kuti uwane yakazara rondedzero yemhedzisiro.
