Lorazepam vs. diazepam: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Lorazepam uye diazepam mishonga yakajairika inoshanda kurapa kusagadzikana, pakati pemamwe mamiriro ehutano hwepfungwa. Mishonga iyi miviri inorondedzerwa se benzodiazepines. Ivo vanoshanda nekuwedzera chiitiko cheGABA, kana gamma-aminobutyric acid, muuropi. Iyo neurotransmitter GABA kiriniki inodzivirira iyo inovhara zvimwe zviratidzo zvetsinga, inowedzera mweya, uye inosimudzira pfungwa yekudzikama.
Ose malorazepam uye diazepam zvirongwa zveShedhiyo IV, sekureva kweDrug Enforcement Administration (DEA). Izvi zvinoreva kuti mishonga iyi, senge mamwe ma benzodiazepines, anotakura njodzi yekuvimbika uye kushungurudzwa. Naizvozvo, ivo vanofanirwa chete kushandiswa senge-yenguva pfupi kurapa pasi pekutarisirwa kwemubatsiri wezvehutano.
Verenga pamusoro kuti udzidze nezveimwe misiyano pakati pe lorazepam ne diazepam.
Ndeupi mutsauko mukuru pakati pe lorazepam vs. diazepam?
Musiyano mukuru pakati pe lorazepam ne diazepam ndewekuti diazepam inogara mumuviri kwenguva refu kupfuura lorazepam. Lorazepam, rinova iro zita rekuti Ativan, rine hafu yeupenyu kusvika 18 maawa . Kune rimwe divi, diazepam, rinova iro zita rekuti Valium, rine hafu yeupenyu inosvika Maawa makumi mana nemasere . Naizvozvo, lorazepam inoonekwa sepakati-kuita benzodiazepine, uye diazepam inoonekwa seyakareba-inoshanda benzodiazepine.
Lorazepam uye diazepam inogadziriswawo, kana kugadziriswa, mumuviri zvakasiyana. Lorazepam inogadziriswa muchiropa nemaitiro inozivikanwa se glucuronidation . Diazepam inogadziriswa muchiropa nema cytochrome enzymes. Nekuda kweizvozvo, diazepam ine yakawanda mikana yekudyidzana nemamwe madhiragi kupfuura lorazepam.
Lorazepam inowanikwa mumapiritsi egeneral ane simba e0.5 mg, 1 mg, uye 2 mg. Izvo zvinouyawo semhinduro yemuromo uye mhinduro yejekiseni. Ativan inowanikwa muma generic mahwendefa emuromo aine masimba e2 mg, 5 mg, uye 10 mg. Ativan inogona zvakare kupihwa seyemuromo mhinduro, mhinduro yejekiseni, uye rectal gel.
| Misiyano mikuru pakati pe lorazepam vs. diazepam | ||
|---|---|---|
| Lorazepam | Diazepam | |
| Kirasi yemishonga | Benzodiazepine | Benzodiazepine |
| Brand / generic chinzvimbo | Brand uye generic vhezheni iripo | Brand uye generic vhezheni iripo |
| Chii chinonzi zita rechiratidzo? | Ativan | Valium |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa remuromo Oral solution Mhinduro yejekiseni | Hwendefa remuromo Oral solution Mhinduro yejekiseni Rectal gel |
| Ndeipi muyero wakajairwa? | Nezve kufunganya: Kutanga dosi: 2 kusvika 3 mg nemuromo 2 kusvika katatu pazuva Maintenance dose: 2 kusvika 6 mg 2 kusvika katatu pazuva | Nezve kufunganya: 2 kusvika 10 mg nemuromo 2 kusvika 4 nguva pazuva |
| Inguva yakareba sei kurapwa kwacho? | Pasina kupfuura mwedzi mina | Pasina kupfuura mwedzi mina |
| Ndiani anowanzoshandisa mushonga? | Vakuru nevana vane makore gumi nemaviri zvichikwira | Vakuru, vana, uye vacheche mwedzi mitanhatu zvichikwira |
Mamiriro ezvinhu anorapwa ne lorazepam vs. diazepam
Lorazepam uye diazepam vanoita seanodzvinyirira kudzikisira zviratidzo zvekushushikana, sekushushikana kwakanyanya uye kunetseka kufunga zvakajeka. Lorazepam uye diazepam ese ari maviri FDA anotenderwa kurapa kusagadzikana uye kusagadzikana kwekushushikana, sekushushikana kwekutya uye kutya kwekutyisa.
Kunge mamwe benzodiazepines, lorazepam uye diazepam inogona kushandiswa kurapa kusagadzikana kwekubatwa, kana pfari. Izvo zvinogona zvakare kushandiswa semberi yemishonga usati wavhiyiwa kuitira chinangwa chekunyaradza.
Diazepam zvakare FDA inogamuchirwa kurapa doro rekusiya chirwere uye mhasuru spasms. Pamusoro pekurapa kusagadzikana, lorazepam inobvumidzwawo kurapa kushaya hope kunokonzerwa nekushushikana. Zvimwe zvekushambadzira-zvinyorwa zvinogona kuwanikwa mutafura iripazasi.
| Mamiriro | Lorazepam | Diazepam |
| Kushungurudzika kusagadzikana | Ehe | Ehe |
| Kushaya hope kunokonzerwa nekushushikana | Ehe | Kunze-chitaridzi |
| Doro rekusiya chirwere | Kunze-chitaridzi | Ehe |
| Tsandanyama mhasuru | Kunze-chitaridzi | Ehe |
| Kushungurudzika kwepfungwa | Ehe | Ehe |
| Mamiriro epilepticus | Ehe | Ehe |
| Sedation kana preedication usati wavhiyiwa | Ehe | Ehe |
Ko lorazepam vs. diazepam inoshanda here?
Inofananidzwa ne placebo, kana pasina mushonga, ese lorazepam uye diazepam anoshanda pakurapa kusagadzikana. Iyo inoshanda zvakanyanya benzodiazepine inoenderana nemamiriro ari kurapwa, mimwe mishonga iri kutorwa, uye chero marapirwo akamboedzwa kare.
Randomized, inodzorwa kiriniki miedzo yakanyanya kuratidza kuti lorazepam uye diazepam zvakaenzana mukuita pakurapa kusagadzikana. Bofu-bofu kliniki kuyedzwa kuenzanisa lorazepam uye diazepam mu134 varwere vanonetseka kwevhiki ina vakaona kuti ese ari maviri madhiragi ainyanya kushanda kupfuura placebo. Nekudaro, lorazepam yakawanikwa ichinyanya kushanda muvarwere vaive nezviratidzo zvakaipisisa pakutanga. Sedation yakanzi ndeye yakakosha mhedzisiro muboka rinotora lorazepam.
Mune network meta-ongororo , midazolam, lorazepam, uye diazepam vakafananidzwa pakurapa chimiro epilepticus, kubatwa kwakanyanya kwenguva refu, muvana. Dhata rakanyorwa kubva ku16 akasiyana emakiriniki miedzo yakawana kuti midazolam uye lorazepam zvainyanya kushanda kupfuura diazepam.
Iyi fananidzo ndeyezvizhinji ruzivo ruzivo. Tsvaga zano rekurapa kubva kuna chiremba kana mupi wezvehutano usati washandisa benzodiazepine. Anokupa hutano anozoongorora nezvekurapa kuti aone kuomarara kwemamiriro ako uye kutonga mamwe mamiriro ehutano hwepfungwa.
Kuvhara uye mutengo kuenzanisa kwe lorazepam vs. diazepam
Generic lorazepam inowanzo kufukidzwa neakawanda maMedare uye zvirongwa zveinishuwarenzi. Pasina inishuwarenzi, avhareji yemutengo wemari unogona kuva $ 25 kwemakumi matatu, 0.5 mg mapiritsi. ImweCareCare lorazepam coupon inogona kuunza mutengo pasi kusvika pamadhora mapfumbamwe.
Kufanana nemamwe madhiragi akajairika, diazepam inowanzo kufukidzwa neMedare uye zvirongwa zveinishuwarenzi. Mari yepakati yemari yegeneral diazepam ingangoita madhora makumi maviri nemana makumi matatu, 0.5 mg mapiritsi. Inofananidzwa ne lorazepam, diazepam inogona kunge iri yakachipa zvishoma zvichienderana nefesi yako. Kushandisa CouponCare diazepam coupon kunogona kudzikisa mutengo kusvika kumadhora manomwe pamishonga yemishonga.
| Lorazepam | Diazepam | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 2 kusvika 6 mg 2 kusvika katatu pazuva | 2 kusvika 10 mg nemuromo 2 kusvika 4 nguva pazuva |
| Chaizvoizvo Medicare copay | $ 0– $ 25 | $ 0– $ 12 |
| SingleCare mutengo | $ 8 + | $ 6 + |
Zvakajairika mhedzisiro mhedzisiro ye lorazepam vs. diazepam
Lorazepam uye diazepam, sedzimwe benzodiazepines, zvinonyanya kukonzera mhedzisiro mune yepakati tsinga system (CNS). Kazhinji mhedzisiro ye lorazepam , kana Ativan, sedation, dzungu, kushaya simba, uye kusagadzikana, kana kurasikirwa kwekubatana. Mhedzisiro inowanzoitika mhedzisiro ye diazepam, kana Valium, kukotsira, kuneta, kushaya simba kwemhasuru, uye kurasikirwa nekubatana.
Mimwe mhedzisiro inogona kuitika inogona kusanganisira ndangariro matambudziko. Iko kuitika kwemhedzisiro kunowanzoenderana nedosi yemushonga wakatorwa. Zvimwe zvakakomba mhedzisiro mhedzisiro zvinonzi zvine yakakwira doses ye benzodiazepines. Matambudziko akakomba, anosanganisira mweya wekufema, kana kufema zvishoma, zvinogona kuratidza zvekukurumidzira kwekurapa.
| Lorazepam | Diazepam | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kugara | Ehe | 16% | Ehe | * |
| Kukotsira | Ehe | * | Ehe | * |
| Kuneta | Ehe | * | Ehe | * |
| Dzungu | Ehe | 7% | Ehe | * |
| Kushaya simba | Ehe | 4% | Ehe | * |
| Kukanganisika kubatana | Ehe | 3% | Ehe | * |
| Matambudziko ekurangarira | Ehe | * | Ehe | * |
* haina kutaurwa
Kakawanda hakubvi pane data kubva kumusoro-kuenda-kumusoro kutongwa. Izvi zvinogona kunge zvisiri rondedzero izere yemhedzisiro mhedzisiro inogona kuitika. Ndokumbira utarise kuna chiremba wako kana mupi wezvehutano kuti udzidze zvimwe.
Kwayaka: DailyMed ( Lorazepam ), Zuva Nezuva ( Diazepam )
Kubatana kwemishonga ye lorazepam vs. diazepam
Lorazepam uye diazepam inonyanya kudyidzana nemimwe mishonga inobata iyo yepakati nervous system (CNS). Kutora aya benzodiazepines nemishonga senge maopioid, barbiturates, antipsychotic, antidepressants, uye anticonvulsants zvinogona kutungamira mukuwedzera CNS-inoshungurudza mhedzisiro, senge dzungu, kuvhiringidzika, uye kukotsira. Iyo antigout mishonga probenecid inogona kukanganisa metabolism ye benzodiazepines uye inotungamira kune yakawedzera mhedzisiro.
Iko kushandiswa kweiyo theophylline kana aminophylline kunogona kupokana nekunyaradza mhedzisiro ye benzodiazepines. Udza chiremba wako kana ukatora imwe yemishonga iyi usati watanga benzodiazepine.
Diazepam inogadziriswa nemamwe maP450 enzymes nepo lorazepam isiri. Mimwe mishonga inokwanisa kuvhara aya maenzayimu, ayo anokanganisa mashandiro anoita diazepam mumuviri. Izvi zvinogona kukonzeresa kusanganisa mhedzisiro mhedzisiro ye diazepam. Zvinodhaka senge ketoconazole, cimetidine, uye omeprazole inogona kusangana ne diazepam uye inotungamira mukuwedzera sedation.
Antacids senge calcium carbonate uye magnesium hydroxide inogona kudzikisa kunwa kwe diazepam mumuviri. Izvi zvinogona kuchinja mashandiro anoita diazepam.
| Zvinodhaka | Kirasi yemishonga | Lorazepam | Diazepam |
| Oxycodone Hydrocodone Codeine Morphine | Opioid | Ehe | Ehe |
| Phenobarbital Pentobarbital Achiparanga | Barbiturate | Ehe | Ehe |
| Clozapine Lurasidone Olanzapine | Antipsychotic | Ehe | Ehe |
| Fluoxetine Fluvoxamine Amitriptyline Doxepin | Kushungurudzika | Ehe | Ehe |
| Valproate Phenytoin Clobazam | Anticonvulsant | Ehe | Ehe |
| Wedzerikure | Antigout mumiriri | Ehe | Ehe |
| Kwayedza Aminophylline | Methylxanthine | Ehe | Ehe |
| Ketoconazole | Antifungal mumiriri | Kwete | Ehe |
| Cimetidine | H2-anogamuchira anopikisa | Kwete | Ehe |
| Omeprazole | Proton pombi inhibitor | Kwete | Ehe |
| Calcium kabhoni Magnesium hydroxide | Antacid | Kwete | Ehe |
Bvunza nyanzvi yezvehutano kune kumwe kudyidzana kwezvinodhaka.
Yambiro dzerorazepam vs. diazepam
Iko kushandiswa kweopioid ine benzodiazepines kunofanirwa kudzivirirwa. Kana ikashandiswa pamwechete, benzodiazepines uye maopioid zvinogona kuwedzera njodzi yekufema kushushikana, coma, uye kunyangwe kufa. Varwere vanofanirwa kutariswa zvakanyanya kana aya makirasi maviri emishonga achitorwa pamwechete.
Lorazepam uye diazepam vari Purogiramu IV zvinodhaka . Avo vane nhoroondo yakapfuura yedoro kana kushandisa zvisina kufanira zvinodhaka vanogona kunge vari panjodzi yakanyanya yekutsamira uye kushungurudzwa ne benzodiazepines. Kuvimba uye kushungurudzwa kunogona kuwedzera njodzi yekuwedzeredza ne benzodiazepines. Zviratidzo nezviratidzo zve benzodiazepine overdose zvinosanganisira kurasikirwa kwakanyanya kwekubatana, zvine ngozi kudzikira kweropa (hypotension), mweya wekufema, uye koma.
Iyo chete yakaderera inoshanda dosi ye lorazepam kana diazepam ndiyo inofanira kushandiswa. Bvunza chiremba kana nyanzvi yezvehutano pane dzimwe yambiro pamwe nechengetedzo.
Inowanzo bvunzwa mibvunzo nezve lorazepam vs. diazepam
Chii chinonzi lorazepam?
Lorazepam izita rakajairika reAtivan. Icho chikamu chekirasi yemishonga inozivikanwa se benzodiazepines. Lorazepam inowanikwa sehwendefa remuromo musimba re0.5 mg, 1 mg, uye 2 mg. Inogona zvakare kupihwa semhinduro yemumuromo kana jekiseni. Lorazepam inobvumidzwa kurapa kushushikana uye kushaya hope kunokonzerwa nekushushikana. Inogona zvakare kushandiswa sekurapa kwekutadza kwekubata kana preedication usati wavhiyiwa.
Chii chinonzi diazepam?
Diazepam inozivikanwa zvakare nezita rayo rezita, Valium. Iyo benzodiazepine iyo FDA inogamuchirwa kurapa kunetseka, doro rekusiya chirwere, uye mhasuru . Inogona zvakare kushandiswa pakubata kusagadzikana uye sedative zvinangwa usati wavhiyiwa. Diazepam inowanikwa mu2 mg, 5 mg, uye 10 mg mapiritsi emuromo. Izvo zvinouyawo semhinduro yemumuromo, jekiseni, uye rectal gel.
Ko lorazepam vs. diazepam yakafanana here?
Lorazepam uye diazepam ese ari maviri benzodiazepines, asi haana kufanana. Ivo vanouya nenzira dzakasiyana uye vane akasiyana FDA-anotenderwa mashandisiro. Ivo zvakare vane akasiyana zanhuriro zera: Lorazepam haina kukurudzirwa muvana vari pasi pemakore gumi nemaviri ekuberekwa nepo diazepam isingakurudzirwe muvacheche vari pasi pemwedzi mitanhatu
Lorazepam kana diazepam iri nani here?
Lorazepam uye diazepam mese mishonga inoshanda. Diazepam inogara mumuviri wakareba kupfuura lorazepam. Zvisinei, izvi hazvirevi kuti uri nani mushonga. Kubudirira kwe benzodiazepine kunoenderana nemamiriro ari kurapwa, pakati pezvimwe zvinhu. Bvunza mupi wezvehutano kuti uone kurapa kwakanakira iwe.
Ndinogona here kushandisa lorazepam kana diazepam ndiine nhumbu?
Hazvikurudzirwi kutora lorazepam kana diazepam uchiri nepamuviri. Kunyangwe diazepam inogona kunge yakachengeteka zvishoma kupfuura lorazepam panguva yekuzvitakura, hazvina kukwana zvidzidzo zvakaratidza kuti benzodiazepines yakachengeteka zvachose panguva yepamuviri. Bvunza mupi wezvehutano usati watora benzodiazepine panguva yekuzvitakura.
Ndinogona here kushandisa lorazepam kana diazepam nedoro?
Kubatanidza doro uye benzodiazepines haina kukurudzirwa. Dzose doro nedoro benzodiazepines zvinogona kukonzera CNS mhedzisiro sekukotsira uye dzungu. Kutora zvinhu izvi pamwechete zvinogona kuwedzera njodzi yemhedzisiro uye ovhadhozi.
3 mg lorazepam yakawandisa here?
Muyero wakakodzera we lorazepam unoenderana nemamiriro ari kurapwa. Bvunza chiremba wezvehunyanzvi kuraira kwekurapa uye nemirayiridzo yakakodzera yekuti ungashandise sei mushonga uyu. Chiyero chakazara che lorazepam chinogona kunge chiri chero kubva pa2 kusvika pa6 mg nemuromo kaviri kusvika katatu pazuva.
Ko diazepam inogara kwenguva yakareba kupfuura lorazepam here?
Diazepam inogara kwenguva yakareba kupfuura lorazepam. Inofungidzirwa seyakareba-inoshanda benzodiazepine nehafu yehupenyu hunosvika maawa makumi mana nemasere. Yakareba-inoshanda benzodiazepines inosanganisira Valium (diazepam), Librium (chlordiazepoxide), uye Dalmane (flurazepam).
Zvakaipa kutora Ativan mazuva ese?
Izvo hazviwanzo kukurudzirwa kutora Ativan (lorazepam) kwenguva refu. Hazvina kukwana zvidzidzo zvakaitwa pamusoro pekuchengetedza uye kushanda kweAtivan mwedzi mina yekushandisa. Vamwe vanhu vanokudziridza kuvimba uye kushivirira kune Ativan, izvo zvinogona kukanganisa mashandiro azvo nekufamba kwenguva. Ativan inongofanirwa kushandiswa sekurairwa neanopa hutano.
Lorazepam inokurumidza kuita?
Lorazepam ari wepakati-anoshanda benzodiazepine. Mhedzisiro yelorazepam inogona kunzwika mukati me1 kusvika 1.5 maawa mushure mekutora. Hafu yeupenyu yelorazepam iri kutenderera gumi kusvika kumaawa makumi maviri. Zvimwe zviri pakati-kuita benzodiazepines zvinosanganisira Xanax (alprazolam), Klonopin (clonazepam), uye Restoril (temazepam).
