Estrace vs. Premarin: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Kana iwe ukawana zviratidzo zvekumira kwemwedzi, senge kupisa kunopisa, husiku hweziya , matambudziko ekurara, uye kuoma kwechikadzi, wako mupi wezvehutano anogona kunge akataura nezvehomoni kutsiva kurapwa kana estrogen kurapwa. Zviratidzo zvekuguma kuenda kumwedzi zvinoitika kana muviri ukaita mashoma esrogen, saka mishonga inotsiva estrogen inogona kubatsira kugadzirisa zviratidzo izvi, uye zvakare kubatsira kudzivirira osteoporosis.
Mune vakadzi vane chibereko, kurapa kwehomoni inosanganisira zvese estrogen uye progesterone. Mune vakadzi vane chibereko, estrogen yega inowedzera njodzi yekenza yemendometri.
Vakadzi vasina chibereko (vane hysterectomy) havadi kutora progesterone ine estrogen. Vakadzi ava vanogona kushandisa zvigadzirwa zveesrogen-chete seEstrace kana Premarin.
Estrace uye Premarin mishonga miviri-yemazita inoratidzirwa pakurapa zviratidzo zvekuguma kuenda kumwedzi. Ose madhiragi anotenderwa neUnited States Chikafu neDrug Administration (FDA). Ivo vari mukirasi yemishonga inonzi inonzi estrogens uye inozivikanwa zvakare sehomoni kutsiva kurapa. Ivo vanowanikwa mune akasiyana mafomati, anosanganisira makirimu uye mapiritsi. Kunyangwe zvese zviri zviviri Estrace uye Premarin zvine estrogen, iwo haana kunyatso kufanana. Enderera kuverenga kuti udzidze zvakawanda nezve Estrace uye Premarin.
Ndeupi mutsauko mukuru pakati peEstrace nePremarin?
Estrace inowanikwa mu brand uye generic fomu uye ine chinongedzo estradiol . Estrace inowanikwa semukadzi echikadzi estrogen cream, uye zvakare sehwendefa remuromo.
Premarin inowanikwa sezita-zita zvinodhaka chete. Iyo ine conjugated estrogens, yakanatswa kubva kune nhumbu mares 'weti (saka zita rekuti Premarin- PREgnant MARes urINe). Premarin inowanikwa seyakadzi estrogen kirimu, piritsi remuromo, kana jekiseni.
| Misiyano mikuru pakati peEstrace uye Premarin | ||
|---|---|---|
| Estrace | Premarin | |
| Kirasi yemishonga | Estrogens / hormone kutsiva kurapa | Estrogens / hormone kutsiva kurapa |
| Brand / generic chinzvimbo | Brand uye generic | Brand |
| Chii chinonzi generic zita? | Estradiol | Yakagadziriswa estrogens |
| Ndeapi mafomu (s) ayo mushonga unouya? | Vaginal cream, yemuromo piritsi | Vaginal cream, yemuromo piritsi, jekiseni |
| Ndeipi muyero wakajairwa? | Kirimu: 2 kusvika ku4 magiramu vaginally zuva nezuva kwevhiki 1-2, uye zvishoma nezvishoma kudzikira kune yekuchengetedza dosi ye1 gramu 1-3 nguva pasvondo Mahwendefa: anosiyana | Kirimu: 0,5 magiramu mukati memadzimai kaviri pavhiki Mahwendefa: anosiyana |
| Yakareba sei iyo yekurapa? | Zvinosiyana | Zvinosiyana |
| Ndiani anowanzoshandisa mushonga? | Vakadzi vePostmenopausal, pano neapo muvarume kune zvimwe zvinoratidza (ona pazasi) | Vakadzi vePostmenopausal, pano neapo muvarume kune zvimwe zvinoratidza (ona pazasi) |
Mamiriro ezvinhu akarapwa naEstrace uye Premarin
Estrace cream uye Premarin kirimu inobata zvine mwero kune zvakanyanya zviratidzo zvevakadzi uye vulvar atrophy (kuonda, kuomesa, uye kuzvimba) nekuda kwekuguma kuenda kumwedzi.
Mune fomu yepiritsi, Estrace naPremarin vanobata mamwe mamiriro akasiyana akanyorwa muchati pazasi.
| Mamiriro | Estrace | Premarin |
| Moderate kune zvakakomba zviratidzo zvevulvar / vaginal atrophy nekuda kwekuguma kuenda kumwedzi | Hongu (kirimu) | Hongu (kirimu) |
| Kurapa kwe hypoestrogenism nekuda kwe hypogonadism, castration, kana yekutanga ovarian kutadza | Hongu (hwendefa) | Hongu (hwendefa) |
| Kurapa kwekenza yemazamu (yekunyaradza chete) mune vamwe vakadzi nevarume vane metastatic chirwere | Hongu (hwendefa) | Hongu (hwendefa) |
| Kurapa kwepamberi uyerogen-inotenderera carcinoma yeprostate (yekungopora chete) | Hongu (hwendefa) | Hongu (hwendefa) |
| Kudzivirira postmenopausal osteoporosis yevakadzi vari panjodzi huru, apo mishonga isiri-estrogen isina kukodzera | Hongu (hwendefa) | Hongu (hwendefa) |
| Kurapa kweatrophic vaginitis uye kraurosis vulvae | Kunze-chitaridzi | Hongu (kirimu) |
| Kurapa kwepakati nepakati zvakanyanya dyspareunia (kusangana kunorwadza) nekuda kwekuguma kuenda kumwedzi | Kunze-chitaridzi | Hongu (kirimu) |
| Kurapa kwekuenzanisira kusvika kwakakomba zviratidzo zvevasomotor nekuda kwekuguma kuenda kumwedzi | Hongu (hwendefa) | Hongu (hwendefa) |
Estrace kana Premarin inoshanda here?
Zvidzidzo zvinoratidza kuti kana tichienzanisa zvigadzirwa zveesrogen, estradiol (chinongedzo muEstrace) uye conjugated estrogens (chinongedzo muPremarin) zvinoshanda zvakaenzana pakurapa zviratidzo zvekuguma kuenda kumwedzi. Vaginal makirimu zvinoshanda uye zvakanaka-akashivirira.
Mubatsiri wako wehutano anogona kuona kuti ndeupi mushonga unokodzera iwe, uchifunga nezvezviratidzo zvako, mamiriro ekurapa, uye nhoroondo yekurapa.
Kuvhavha uye mutengo kuenzanisa kweEstrace vs. Premarin
Inishuwarenzi uye Medicare zvirongwa zvemishonga zvinowanzovhara Estrace uye Premarin.
Yakajairika generic Estrace kunyorerwa ndeyechubhu yekirimu uye inodhura madhora makumi matatu nemasere kana iwe uchibhadhara muhomwe, asi kushandisa mahara SingleCare koponi kunogona kuunza mutengo pasi kungangoita madhora matanhatu.
Chairo chinyoreso chechubhu Premarin inodhura madhora mazana maviri nemakumi mashanu ekubuda muhomwe. Kadhi reSingleCare rinogona kuunza mutengo kusvika pasi kusvika $ 198.
Sezvo zvirongwa zvichisiyana, bata wako inishuwarenzi mupi wezve kufukidza ruzivo.
| Estrace | Premarin | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Zvakawanda | 1 chubhu | 1 chubhu |
| Chaizvoizvo Medicare copay | $ 1- $ 36 | $ 2- $ 451 |
| SingleCare mutengo | $ 6 + | $ 198 + |
Zvakajairika mhedzisiro mhedzisiro yeEstrace vs. Premarin
Iwo akajairika mhedzisiro mhedzisiro yeEstrace uye Premarin kirimu inosanganisira yekushandisa saiti maitiro sekurumwa, kubuda, uterine kubuda ropa, uye kuzvimba. Uyezve, kurwadziwa nemusoro uye kurwadziwa kwepamuviri kunogona kuitika. Iyo muzana yemhedzisiro haina kusanganisirwa mune yekutsanangura ruzivo rweEstrace.
Zvakajairika mhedzisiro mhedzisiro yeEstrace uye Premarin mune fomu rehwendefa akawedzera maitiro. Mimwe yemhedzisiro iyi inosanganisira kurwadziwa mudumbu kana musana, kushaya simba, kuzvimba, kurwadziwa nemusoro, kuzvimbirwa, gasi, kusvotwa, kuwedzera huremu, kushushikana, kutya, dzungu, kunyorova kwepazamu / kurwadziwa / shanduko, uye kubuda kwemukadzi, kubuda ropa, kana mbiriso chirwere.
Iyi haisi rondedzero izere yemhedzisiro. Mimwe mhedzisiro yakaipa inogona kuitika. Bvunza wako mupi wezvehutano kuti utaure nezvemativi mhedzisiro aunotarisira, uye maitiro ekugadzirisa.
| Estrace kirimu | Premarin kirimu | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Kutemwa nemusoro | Ehe | % haina kutaurwa | Ehe | 3-5% * |
| Kurwadziwa kwepamuviri | Ehe | % haina kutaurwa | Ehe | 4% |
| Itching | Ehe | % haina kutaurwa | Ehe | 1-2% |
| Kusangana nemukadzi | Kwete | - | Ehe | 3-4% |
| Kubuda ropa muchikadzi | Ehe | % haina kutaurwa | Ehe | 1-2% |
| Vaginal kuzvimba | Ehe | % haina kutaurwa | Ehe | 1-2% |
| Vaginal hutachiona / mbiriso hutachiona | Ehe | % haina kutaurwa | Ehe | 3-4% |
* zvinoenderana nesero frequency
Kwayaka: DailyMed ( Estrace kirimu ), Zuva Nezuva ( Premarin kirimu )
Kubatana kwezvinodhaka zveEstrace vs. Premarin
Estrace kana Premarin inogona kukanganiswa nemamwe madhiragi anogadziriswa neiyo enzyme inonzi cytochrome-p 450 3A4. Zvinodhaka zvinodzivisa iyo enzyme zvinogona kudzora kugadziriswa kwemuviri weEstrace kana Premarin, zvichireva kuti Estrace kana Premarin inogona kugara mumuviri kwenguva yakareba, ichikonzera mimwe mhedzisiro. Zvakare, mishonga inokonzeresa iyo enzyme inogona kukonzera kuti muviri utore Estrace kana Premarin nekukurumidza, ichiita kuti isanyanya kushanda. Bvunza wako mupi wezvehutano nezve zvinobvira kudyidzana zvinodhaka.
| Zvinodhaka | Kirasi yemishonga | Estrace | Premarin |
| Clarithromycin Erythromycin Muchero wemazambiringa Itraconazole Ketoconazole Ritonavir | CYP3A4 enzyme inhibitors | Possible | Possible |
| Carbamazepine Phenobarbital Rifampin Wort St. | CYP3A4 enzyme inducers | Possible | Possible |
Yambiro dzeEstrace uye Premarin
Estrace uye Premarin vane yambiro yebhokisi , inova yambiro yakasimba inodiwa neDFA. Nekuti systemic yekumwa inogona kuitika neEstrace kana Premarin kirimu, yambiro dzinoshanda kune ese mafomati.
Estrogen chete:
- Kushandisa estrogen yoga (isina progestin) mumukadzi ane chibereko kunowedzera mukana wekenza yemendometri. Kuwedzera progestin kurapa estrogen kunogona kudzikisa njodzi yekenza yemendometri (asi inogona kuwedzera njodzi yekenza yemazamu). Vakadzi vePostmenopausal vane kubuda ropa zvisina kujairika vanofanirwa kuyedzwa kuti vatonge kunze kwekuipa.
- Usashandise estrogen yega kudzivirira chirwere chemwoyo kana kuora mwoyo. IWomen's Health Initiative (WHI) kudzidza akawana njodzi yakawedzera yekurohwa uye DVT (yakadzika vein thrombosis, kana kuvhara ropa mugumbo) mune vakadzi vanotevera postopaopausal vakatora estrogen voga (vasina progestin).
- Chidzidzo ichi chakaratidzawo njodzi yekuwedzera kuora mwoyo mumadzimai ekumapedza kuenda kumwedzi vakatora estrogen voga.
Estrogen pamwe neprogestin:
- Usashandise estrogen pamwe neprogestin kudzivirira chirwere chemwoyo kana kuora mwoyo. Chidzidzo cheWHI chakawana njodzi dzakakwira dzeDVT, PE (pulmonary embolism), sitiroko, uye MI mune vakadzi vanoteveraopaopausal vakatora estrogen pamwe neprogestin Chidzidzo ichi chakaratidzawo njodzi yakakwira yekuve neundangariro muvakadzi vanotevera kuenda kumwedzi vakatora estrogen pamwe neprogestins.
- Chidzidzo cheWII chakaratidzawo njodzi yakawedzera yekenza yemazamu inopinda neestrogen pamwe neprogestin.
Naizvozvo, estrogens, zvisinei nekuti yakatemwa pamwe kana isina progestin, inofanirwa kupihwa pane yakaderera dhosi uye kwenguva pfupi yenguva. Taura nemupi wako wezvehutano nezve njodzi kana mabhenefiti emhando dzakasiyana dzehormone kutsiva kurapwa.
Chiremba wako anokupa rairo yekurapa pakuongorora. Vakadzi vese vanofanirwa kuve nekuongororwa zamu kwegore negore nachiremba wehutano uye vozviongorora wega wega pamwedzi. Vakadzi vese vanofanirwawo kunge vane mammography zvinoenderana nezera, njodzi zviitiko, uye nhoroondo.
Dzimwe yambiro dzeEstrace uye Premarin inotevera.
Usashandise Estrace kana Premarin kana iwe uine:
- Kusaziva zvisina kujairika kubuda ropa
- Kenza yemazamu (inozivikanwa, inofungidzirwa, kana nhoroondo)
- Estrogen-inoenderana neoplasia (inozivikanwa kana kufungidzirwa)
- DVT kana pulmonary embolism (inoshanda kana nhoroondo)
- Kushanda kana nhoroondo yetromboembolic chirwere (sitiroko, MI)
- Yapfuura anaphylactic reaction kune estrogen
- Chiropa chirwere
- Thrombophilic kusagadzikana
- Kubata (kunozivikanwa kana kufungidzirwa)
Kubatanidzwa kwehomoni yekurapa (estrogen pamwe neprogestin) kunogona kuwedzera njodzi yekenza yemazai.
Vakadzi vePostmenopausal vanotora estrogen vane kuwedzera kwenjodzi yechirwere chenduru chinoda kuvhiyiwa.
Mune vanhu vanotora estrogens, matambudziko ekuona akaitika. Tsvaga kurapwa nekukurumidza kana iwe uchinge warasikirwa nechiono (chakasarudzika kana chakakwana), zvakapetwa kaviri, ziso kuputika, kana migraine.
Muzviitiko zvisingawanzoitika, kusagadzikana kweanenge aitika. Kana iwe uine mikoko, kuchenesa, kunetseka kufema, kurutsa, kana kuzvimba kwechiso, miromo, rurimi, maoko, kana tsoka, tsvaga kurapwa kwechimbichimbi ipapo ipapo. Estrogen mishonga inogona kuwedzera angioedema zviratidzo mumadzimai ane nhaka angioedema.
Taura nemupi wako wezvehutano nezve njodzi idzi usati watora Estrace kana Premarin, kuti uone kana mushonga wacho wakachengeteka kwauri.
Inowanzo bvunzwa mibvunzo nezve Estrace vs. Premarin
Chii chinonzi Estrace?
Estrace mushonga unotsiva mahormone une estradiol. Iyo inoshandiswa kune akasiyana maratidziro, kazhinji kazhinji kune zviratidzo zvekuguma kuenda kumwedzi. Estrace inowanikwa seyakagwinya kamu cream pamwe chete nemuromo piritsi.
Chii chinonzi Premarin?
Premarin zvakare ihomoni kutsiva mushonga. Premarin ine conjugated estrogens. Iyo inoshandiswa pakuratidzira kwakati wandei, kazhinji kazhinji kune zviratidzo zvekuguma kuenda kumwedzi. Premarin inowanikwa sehwendefa remuromo, intravaginal cream, uye jekiseni.
Estrace uye Premarin zvakafanana here?
Estrace uye Premarin zvakafanana, asi kwete zvakangofanana. Ruzivo rwuri pamusoro rwunoratidzira mutsauko uripo pakati pemishonga iyi miviri.
Estrace kana Premarin zvirinani here?
Ose ari maviri mishonga anoshanda pakurapa kubuda kwemwedzi zviratidzo, zvisinei, iyi mishonga inouya nemhedzisiro uye njodzi. Taura nemupi wako wezvehutano kuti uone kana Estrace kana Premarin yakakukodzera.
Ndinogona here kushandisa Estrace kana Premarin ndichiri nepamuviri?
Kwete. Kana mishonga haifanirwe kushandiswa pakubata.
Ndinogona here kushandisa Estrace kana Premarin nedoro?
Kunwa doro pamwe chete neEstrace kana Premarin inogona wedzera njodzi yako yekenza yemazamu. Bvunza nyanzvi yezvehutano kuti utungamirirwe nedoro nekushandisa chero mamiriro ekurapa aunayo.
Ndeipi imwe sarudzo yakanakisa kune Premarin?
Estrace imwe nzira yakafanana kune Premarin. Mimwe mishonga ine estrogen inosanganisira iyo Vivelle Dot Patch, Climara Patch, kana vaginal estrogen muchimiro cheVagifem vaginal mapiritsi (mapiritsi echikadzi anoshandiswa nemukadzi anoshandisa) kana Estring Vaginal Ring. Taura nemupi wako wezvehutano kuti uone kana mumwe wemishonga iyi wakakodzera iwe.
Isrogen uye estradiol chinhu chimwe chete here?
Estradiol chimiro cheestrogen, ihormone yechikadzi. Zvese zvigadzirwa zveestradiol ndeye estrogen. Nekudaro, kune mamwe mafomu eestrogen pane kungoitwa estradiol. Semuenzaniso, conjugated estrogens (Premarin) ndeimwe nzira yesrogen.
Premarin inokonzera kuora mwoyo here?
Premarin (uye Estrace) ine yambiro yebhokisi nezve dementia. Iyo WHI Yekudzidza Yekudzidza yataurwa pamusoro yakawana njodzi yakawedzera yekukuvara kwekutadza kuora mwoyo mumadzimai ekumiraopaopausal avo vakatora estrogen voga kana estrogen ine progestin. Naizvozvo, iko kunyorera ruzivo kunokurudzira kuti estrogen, kunyangwe ikatorwa yega kana neprogestin, inofanirwa kupihwa padosi repasi uye kwenguva pfupi.
Estrace inowedzera here estrogen mazinga?
Estrace (uye Premarin) inowedzera mazinga eestrogen. Kunyangwe iri muchikadzi, pane systemic yekumwa, uye esrogen mazinga anowedzera. Mutapi wako wezvehutano anogona kuona kuti ndechipi chigadzirwa chakakodzera iwe.
