Cymbalta vs. Effexor: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Cymbalta (duloxetine) uye Effexor (venlafaxine) mishonga-zita remishonga inoshandiswa kurapa mamiriro epfungwa senge kushushikana uye kushushikana. Ivo vanowanzo gadzirirwa seanodzvinyirira kuti vabatsire kudzikamisa zviratidzo zvehukuru kushungurudzika kusagadzikana. Zviratidzo zvekushungurudzika kukuru kunogona kusanganisira kusuwa kusingaperi uye kurasikirwa kukuru kwekufarira zviitiko zvezuva nezuva.
Cymbalta naEffexor vese ndevekirasi yemishonga inonzi serotonin uye norepinephrine reuptake inhibitors (SNRIs). Ivo vanoshanda nekuwedzera kuwanikwa kweserotonin uye norepinephrine muuropi. Aya makemikari, kana maurotransmitter, anotendwa kuti anoita basa mukuitika kwehutano hwepfungwa.
Nezve zvinangwa zvekuenzanisa uku, zita rekuti Effexor rinogona zvakare kureva Effexor XR, iro chete zita rechiratidziro Effexor parizvino riri pamusika.
Ndeupi mutsauko mukuru pakati peCymbalta neEffexor?
Cymbalta
Cymbalta ndiro zita rezita reduloxetine. Inowanikwa semuromo wakanonoka-kuburitsa kapuleti nemasimba e20 mg, 30 mg, kana 60 mg. Iyo inowanzo dosed seimwe kapuleti nemuromo kamwe zuva nezuva zvichienderana nemamiriro ari kurapwa. Iyo yakanyanya dhosi pazuva ndeye 120 mg kunyangwe pasina humbowo hwekuti doses yakakura kupfuura 60 mg ipa kuwedzera kwakakosha mukubatsira.
Cymbalta ine hafu-yehupenyu hweanosvika maawa gumi nemaviri. Iyo inonyanya kugadziriswa uye kubviswa kuburikidza nechiropa neitsvo. Kushandiswa kwaro kunofanira kudzivirirwa kune avo vane chiropa chakakomba kana kukanganisika kweitsvo.
Effexor
Effexor ndiro zita rechiratidzo re venlafaxine. Zvisinei, zita rechiratidzo Effexor rinongowanikwa seEffexor XR, kana venlafaxine yakawedzerwa-kuburitsa mapiritsi. Pakarepo-kuburitswa Effexor kwakamiswa nekuti inoda kubviswa kakawanda mukati mezuva rese uye inokonzeresa kusvotwa kupfuura iyo yakawedzerwa-kuburitsa vhezheni.
Effexor XR inouya mumuromo macapsule ane simba e37.5 mg, 75 mg, uye 150 mg. Dosing inogona kusiyana zvichienderana nemamiriro ari kurapwa. Zvisinei, Effexor XR inowanzotorwa kamwe chete zuva nezuva nechinangwa chezuva nezuva che 75 mg uye huwandu hwezuva nezuva hwe225 mg.
SaCymbalta, Effexor inogadziriswa muchiropa uye ine hafu yeupenyu kusvika kumaawa gumi nerimwe . Inogona kushandiswa kune avo vane chiropa kana kukanganisika kweitsvo kana madosi epasi achitorwa.
| Misiyano mikuru pakati peCymbalta neEffexor | ||
|---|---|---|
| Cymbalta | Effexor | |
| Kirasi yemishonga | Serotonin uye norepinephrine reuptake inhibitor (SNRI) | Serotonin uye norepinephrine reuptake inhibitor (SNRI) |
| Brand / generic chinzvimbo | Brand uye generic vhezheni iripo | Brand uye generic vhezheni iripo |
| Chii chinonzi generic zita? | Duloxetine | Venlafaxine |
| Ndeapi mafomu (s) ayo mushonga unouya? | Oral capsule, yakawedzerwa-kusunungurwa | Oral capsule, yakawedzerwa-kusunungurwa |
| Ndeipi muyero wakajairwa? | 60 mg kamwe pazuva | 75 mg kamwe pazuva |
| Yakareba sei iyo yekurapa? | Nguva refu | Nguva refu |
| Ndiani anowanzoshandisa mushonga? | Vakuru nevechiri kuyaruka | Vakuru nevechiri kuyaruka |
Mamiriro ezvinhu akarapwa neCymbalta uye Effexor
Cymbalta is FDA inogamuchirwa kurapa zvakanyanya kushungurudzika kusagadzikana (MDD) uye yakajairika kusagadzikana kusagadzikana (GAD). Inogona zvakare kushandiswa kurapa marwadzo kubva ku fibromyalgia uye chirwere cheshuga neuropathy, pamwe nekurwadziwa kwakanyanya mumhasuru, tendon, ligaments, uye mapfupa. Cymbalta dzimwe nguva inogona kushandiswa kure-chitaridzi kune mamwe matambudziko ekuzvidya mwoyo.
Effexor XR is FDA inogamuchirwa kurapa kwakanyanya kushushikana kwepfungwa (MDD), yakajairwa kunetseka kusagadzikana (GAD), kusagadzikana kwevanhu kusagadzikana (SAD), uye panic disorder (PD). Iyo zvakare dzimwe nguva inoshandiswa kure-chitambi kurapa obsessive-kusagadzikana kusagadzikana (OCD), premenstrual dysphoric disorder (PMDD), uye kurwadziwa.
| Mamiriro | Cymbalta | Effexor |
| Huru kushungurudzika kusagadzikana | Ehe | Ehe |
| Chirwere chekuzvidya mwoyo | Ehe | Ehe |
| Kushungurudzika kwevanhu munharaunda | Kunze-chitaridzi | Ehe |
| Panic kusagadzikana | Kunze-chitaridzi | Ehe |
| Dhiyabhorosi peripheral neuropathic kurwadziwa | Ehe | Kunze-chitaridzi |
| Fibromyalgia | Ehe | Kunze-chitaridzi |
| Husingaperi musculoskeletal kurwadziwa | Ehe | Kunze-chitaridzi |
| Kutarisa-kumanikidza kusagadzikana | Kwete | Kunze-chitaridzi |
| Premenstrual dysphoric kusagadzikana | Kwete | Kunze-chitaridzi |
Cymbalta kana Effexor inoshanda zvakanyanya here?
Kubudirira kweCymbalta kana Effexor kunoenderana nemamiriro ari kurapwa. Zvidzidzo zvishoma kwazvo zvakaenzanisa zvakananga Cymbalta neEffexor. Zvisinei, kana ichienzaniswa ne placebo, Cymbalta neEffexor zvese zvinoshanda zvakanyanya pakurapa mamiriro akaita sekuora mwoyo kukuru.
Chimwe chidzidzo chakabatanidza kliniki dzinoverengeka uye vakaona kuti venlafaxine iri nani pfupi-yekurapa sarudzo yekushungurudzika kukuru kupfuura duloxetine. Venlafaxine, chinhu chinoshanda cheEffexor, chinogona zvakare kusarudzwa kune avo vasingapindure zvakanaka pakurapwa kwekutanga nesarudzo yakasarudzika serotonin reuptake inhibitors (SSRIs) kana tricyclic antidepressants (TCAs). Nekudaro, chidzidzo ichi chakaona kuti pakange pasina misiyano yakakosha mukupindura uye chiyero chekupindura pakati pe duloxetine ne venlafaxine.
Imwe ongororo yakarongeka uchifananidza venlafaxine, duloxetine, uye mamwe maanodzvinyirira senge paroxetine, fluoxetine, uye fluvoxamine. Kuenzaniswa nedzimwe sarudzo, venlafaxine yakawanikwa iri imwe yeanoshanda zvakanyanya mishonga yekudzvinyirira. Nekudaro, ese venlafaxine uye duloxetine akaiswa sevamwe veanodzvinyirira antidipressants, zvine chekuita nemhedzisiro.
Bvunza mupi wezvehutano uyo anonyanya kugadzirisa chirwere chepfungwa kuti akupe kurapa kwakanakira iwe.
Kuvhavha uye mutengo kuenzanisa kweCymbalta vs.Expexor
Cymbalta izita-zita rekunyorerwa mushonga rinoshandiswa pakuora mwoyo. Iyo generic vhezheni, duloxetine, inowanzo kufukidzwa neMedare uye zvirongwa zveinishuwarenzi. Kwekupihwa kwemazuva makumi matatu, avhareji mutengo wekutengesa unogona kudarika $ 470. Iine SingleCare Cymbalta coupon, mutengo weiyo generic vhezheni inotanga pamadhora gumi nemashanu kumafarmacy anotora chikamu.
Mahwendefa eExexor XR anowanikwa kutengwa nemushonga. Mahwendefa eGeneric Effexor XR anowanzo kufukidzwa neMedare uye zvirongwa zveinishuwarenzi. Nemutengo wepakati wepakati pe $ 145, Effexor XR yakachipa pane Cymbalta. Zvisinei, kushandisa Effexor XR coupon kubva kuSingleCare kunogona kuunza mutengo pasi zvakanyanya. Kumbira wemishonga wako weiyo generic uye uwane icho kweinenge $ 15.
| Cymbalta | Effexor | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Zvakawanda | Mahwendefa makumi matatu | Mahwendefa makumi matatu |
| Chaizvoizvo Medicare copay | $ 0– $ 89 | $ 0– $ 1 |
| SingleCare mutengo | $ 15 + | $ 15 + |
Zvakajairika mhedzisiro mhedzisiro yeCymbalta vs. Effexor
Mhedzisiro inowanzoitika yeCymbalta inosanganisira kuda kurutsa, kurwadziwa nemusoro, kuoma muromo, kushushikana kana kukotsira, kupatira, uye kupera simba. Cymbalta inogona zvakare kukonzera manyoka, kudzikira kwechido, kuwedzera kudikitira, uye kurwadziwa nemudumbu, pakati pemimwe mhedzisiro.
Mhedzisiro inowanzoitika yeEffexor kushungurudzika, kurwadziwa nemusoro, kuoma muromo, kushaya simba, uye kusaziva. Effexor inogona zvakare kukonzera kushaya hope, kuzvimbirwa, dzungu, manyoka, uye kudzikira kwekuda kudya.
Ose maCymbalta neEffexor anogona zvakare kukonzera kudzikira kwepabonde drive (libido). Nekudaro, Effexor yakaratidzirwa kukonzera mamwe matambudziko ekusagadzikana pabonde kupfuura Cymbalta.
Ona tafura iri pazasi yezvimwe zvakajairika mhedzisiro yeCymbalta uye Effexor.
| Cymbalta | Effexor | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Nausea | Ehe | 2. 3% | Ehe | 4% |
| Kutemwa nemusoro | Ehe | 14% | Ehe | piri% |
| Muromo wakaoma | Ehe | 13% | Ehe | gumi neshanu% |
| Kukotsira | Ehe | 10% | Ehe | piri% |
| Kushaya simba | Kwete | - | Ehe | piri% |
| Kuneta | Ehe | 9% | Kwete | - |
| Kusarara | Ehe | 9% | Ehe | piri% |
| Kuzvimbirwa | Ehe | 9% | Ehe | 9% |
| Dzungu | Ehe | 9% | Ehe | 16% |
| Manyoka | Ehe | 9% | Ehe | 8% |
| Kuderedza kudya | Ehe | 7% | Ehe | * |
| Kuwedzera kudikitira | Ehe | 6% | Ehe | 1% |
| Marwadzo emudumbu | Ehe | 5% | Ehe | * |
| Yakadzikira libido | Ehe | 3% | Ehe | 5% |
| Asina kujairika kuona | Ehe | 3% | Ehe | 4% |
| Mwoyo palpitations | Ehe | piri% | Ehe | piri% |
* haina kutaurwa
Kakawanda hakubvi pane data kubva kumusoro-kuenda-kumusoro kutongwa. Izvi zvinogona kunge zvisiri runyorwa ruzere rwemhedzisiro mhedzisiro inogona kuitika. Ndokumbira utarise kuna chiremba wako kana mupi wezvehutano kuti udzidze zvimwe.
Kwayaka: DailyMed ( Cymbalta ), Zuva Nezuva ( Effexor )
Kubatana kwezvinodhaka zveCymbalta vs. Effexor
Cymbalta neEffexor hazvifanirwe kushandiswa ne monoamine oxidase inhibitors (MAOIs) senge selegiline uye phenelzine. Cymbalta kana Effexor haifanire kushandiswa mukati memazuva gumi nemana ekumisa MAOI. Zvikasadaro, kune njodzi yakawedzera yeserotonin syndrome, iyo yakaoma mamiriro ayo angangoda kurapwa kwenjodzi.
Panogona zvakare kuve nenjodzi yeserotonin syndrome apo Cymbalta kana Effexor inotorwa padivi peimwe serotonergic drug. Serotonergic zvinodhaka zvinosanganisira kusarudza serotonin reuptake inhibitors (SSRIs) uye tricyclic antidepressants (TCAs). Kuchenjerera kunofanirwa kushandiswa kana uchishandisa serotonergic zvinodhaka neCymbalta kana Effexor.
Zvinodhaka zvakaita separoxetine kana fluoxetine zvinogona kukanganisa metabolism yeCymbalta uye kuwedzera huwandu hweropa. Izvi zvinogona kutungamira kune yakanyanya njodzi yemhedzisiro mhedzisiro neCymbalta.
Cymbalta neEffexor dzinofanirwa kushandiswa nekuchenjerera kana kudzivirirwa neasina-steroidal anti-anogumbura zvinodhaka (NSAIDs) uye anticoagulants. Kushandisa iyi mishonga pamwe chete kunogona kuwedzera njodzi yekubuda ropa.
| Zvinodhaka | Kirasi yemishonga | Cymbalta | Effexor |
| Selegiline Phenelzine Rasagiline | Monoamine oxidase inhibitors (MAOIs) | Ehe | Ehe |
| Paroxetine Sertraline Fluoxetine | Kusarudza serotonin reuptake inhibitors (SSRIs) | Ehe | Ehe |
| Amitriptyline Clomipramine Nortriptyline | Tricyclic antidepressants (TCAs) | Ehe | Ehe |
| Aspirin Ibuprofen Naproxen Diclofenac | Nonsteroidal anti-anogumbura zvinodhaka (NSAIDs) | Ehe | Ehe |
| Warfarin | Anticoagulants | Ehe | Ehe |
Bvunza nyanzvi yezvehutano kune kumwe kudyidzana kwezvinodhaka
Yambiro dzeCymbalta uye Effexor
Kukundikana kwechiropa kwakataurwa pamwe nekushandiswa kweCymbalta. Mune avo vane nhoroondo yekunwa doro zvisina kufanira kana kusagadzikana kwechiropa, Cymbalta inofanirwa kudzivirirwa. Iko kushandiswa kweCymbalta kunofanirwa kumiswa kune avo vanokudziridza zviratidzo zvechiropa kutadza, senge jaundice.
Iko kushandiswa kweCymbalta kana Effexor kunotakura njodzi yeserotonin syndrome, inoitika kana paine kuwandisa kweserotonin muuropi. Zviratidzo zve serotonin syndrome zvinogona kusanganisira kukurumidza kurova kwemoyo, kuwedzerwa kweropa, kudikitira, kudedera, uye fivha.
Cymbalta uye Effexor zvinogona kukonzera kuwedzera kweropa. Avo vane nhoroondo yehigh blood pressure vanofanirwa kuongororwa pavanenge vachirapwa neCymbalta kana Effexor.
Cymbalta uye Effexor inofanira kushandiswa nekuchenjerera kune avo vane nhoroondo yebipolar kusagadzikana kana kugumburwa. Izvi zvinodzvinyirira zvinogona kuita mania, hypomania, kana kubatwa mune vamwe vanhu.
Bvunza mubatsiri wezvehutano kune zvimwe zvinonyeverwa uye matanho neCymbalta neEffexor.
Inowanzo bvunzwa mibvunzo nezve Cymbalta vs. Effexor
Chii chinonzi Cymbalta?
Cymbalta ndiro zita re duloxetine. Iyo inoshandiswa pakurapa kwekutambudzika kukuru uye kusagadzikana kwekushushikana. Iyo inoshandiswawo kurapa marwadzo kubva kune chirwere cheshuga neuropathy uye fibromyalgia. Cymbalta inowanikwa mukuwedzera-kuburitswa makapuru musimba e20 mg, 30 mg, kana 60 mg.
Chii chinonzi Effexor?
Effexor ndiro zita rekuti venlafaxine. Iyo inoshandiswa pakurapa kweakanyanya kushushikana kusagadzikana, kwakajairika kusagadzikana kusagadzikana, kusagadzikana kwevanhu kusagadzikana, uye kutya chirwere. Nguva Dzose Effexor yamiswa; zvisinei, mapiritsi eExexor XR anowanikwa musimba re 37.5 mg, 75 mg, uye 150 mg.
Ko Cymbalta neEffexor zvakafanana here?
Cymbalta uye Effexor ese ari maviri serotonin uye norepinephrine reuptake inhibitors (SNRIs). Asi ivo havana kufanana mushonga. Kunze kwekurapa kushushikana kukuru uye kushushikana, Cymbalta iri zvakare FDA inogamuchirwa kurapa mamwe marudzi ekurwadziwa kwetsinga. Kune rimwe divi, Effexor is FDA inogamuchirwa kurapa kutyisidzira uye kushungurudzika munharaunda.
Cymbalta kana Effexor iri nani here?
Iyo iri nani antidepressant inoenderana nemamiriro ari kurapwa uye mimwe mishonga iyo munhu angave ari kutora. Venlafaxine inogona kunge iri nzira inoshanda yekurapa kwenguva pfupi yekushushikana. Nekudaro, inogona kuve nekushivirira kwakaderera kupfuura Cymbalta maererano nemhedzisiro, sekushomeka pabonde.
Ndinogona here kushandisa Cymbalta kana Effexor ndichiri nepamuviri?
Hapana ongororo dzakajeka dzakaratidza kuti Cymbalta kana Effexor inogona kunge yakachengeteka panguva yekuzvitakura. Anodzvinyirira anofanirwa chete kushandiswa panguva yekuzvitakura kana mabhenefiti akakunda njodzi dzinogona kuitika. Mune zvimwe zviitiko, Cymbalta kana Effexor ingangoda kushandiswa kudzora zviratidzo zvekuora mwoyo panguva yepamuviri. Bvunza mupi wezvehutano nezvezvehutano usati washandisa Cymbalta kana Effexor uchiri nepamuviri.
Ndinogona here kushandisa Cymbalta kana Effexor nedoro?
Doro zvine mwero zvinogona kunge zvakachengeteka uchitora Cymbalta kana Effexor. Nekudaro, kunwa doro uchitanga kurapwa neCymbalta kana Effexor kunogona kutungamira mukuwedzera dzungu kana kutsimwaira. Zvinogona kurairwa kuti urege kunwa doro kusvikira rave nemazuva mashoma mushure mekutanga kurapwa.
Effexor inokanganisa ndangariro here?
Iko hakuna humbowo hwekuti Effexor inobata zvakananga ndangariro. Effexor XR yave ichizivikanwa nekukonzera hyponatremia, kana yakaderera sodium mazinga muropa, kunyanya kana diuretics iri kutorwawo. Zviratidzo uye zviratidzo zvehyponatremia zvinosanganisira kutemwa nemusoro, kuvhiringidzika, uye kukanganisika kwendangariro. Chiremba wako anogona kukurudzira kumisa Effexor XR kusvikira iyo hyponatremia yagadzirisa.
Ndeipi imwe nzira yakanaka kune Cymbalta?
Cymbalta inosarudza serotonin uye norepinephrine reuptake inhibitor (SNRI). Dzimwe SNRI dzinosanganisira Effexor (venlafaxine), Pristiq (desvenlafaxine) , uye Savella (milnacipran). Taura nemupi wezvehutano nezve zvingangoita antidepressant kurapwa sarudzo iwe.
Zvakaipa sei kubviswa kweEffexor?
Muyero weEffexor unofanirwa kutapirirwa zvishoma nezvishoma kubatsira kudzivirira zvakakomba zviratidzo zvekudzora. Kuregedza kusagadzikana kweEffexor kunogona kutungamira kuzviratidzo senge kusvotwa, dzungu, kurutsa, kurota zvinotyisa, kushatirwa, uye kutemwa nemusoro. Zviratidzo zvekudzima zveEexexor zvinogona zvakare kusanganisira paresthesias, kana kupenya kwekunzwa paganda.
