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Furosemide mhedzisiro uye maitiro ekuzvidzivirira

Drug Info Furosemide ndeye diuretic inorapa edema uye hypertension asi inogona kuburitsa mhedzisiro. Tarisa uone yedu runyorwa rweyakajairika uye yakakomba mhedzisiro.

Furosemide (zita rezita: Lasix ) generic prescription diuretic inobata edema (kuchengetedza kwemvura) nekuda kwekushushikana kwemoyo kukundikana, cirrhosis yechiropa, kana chirwere cheitsvo. Furosemide inobatawo kuwedzera kweBP (yakakwira BP) uye pulmonary edema (fluid mumapapu).

Furosemide inowedzera huwandu hwemvura uye munyu unobuditswa mumuguta, zvichideredza zvinwiwa mumatumbu emuviri pamwe neropa. Seye loop diuretic, furosemide inoshanda pane imwe nharaunda anatomical muitsvo, ichiita kuti ibudirire kune vanhu vane hurema hweitsvo basa.

Kufanana neese diuretics, furosemide inogona kuburitsa mhedzisiro, kubatana nemamwe madhiragi, uye kuwedzera mamiriro ehutano aripo.

RELATED: Dzidza zvakawanda nezve furosemide

Zvakajairika mhedzisiro mhedzisiro ye furosemide

Furosemide ine mamwe mhedzisiro anokanganisa imwe kana akawanda masisitimu mumuviri.Tanowanzozivikanwa kwenguva pfupi mhedzisiro zvinosanganisira:

Kuwedzera weti
Low electrolyte mazinga (pasi sodium, magnesium, calcium, kana potassium mazinga)
Dzungu
Nausea
Kusvipa
Manyoka
Dumbu rinorwadza
Kupererwa nechido
Kamwe kamwe kudonha kweropa kana wakamira (orthostatic hypotension)
Tsandanyama tsandanyama
Kushaya simba
Unhu
Kurira munzeve
Kutemwa nemusoro
Kuona kwakashata
Akawedzera mashuga eropa (hyperglycemia)
Yakawedzera cholesterol nemafuta (triglycerides) muropa
Kuwedzeredza uric acid (hyperuricemia)
Kuwedzera kwechiropa enzymes
Jekiseni saiti kurwadziwa (paunopihwa furosemide jekiseni)
Rash kana kuchenesa
Kunzwisisa kuchiedza (photosensitivity)

Yakakomba mhedzisiro mhedzisiro ye furosemide

Furosemide ine akati wandei zvakakomba uye zvinogona kuve nenjodzi mhedzisiro. Izvi zvinosanganisira:

Kupera mvura mumuviri
Yakanyanya electrolyte kupera
Ropa rakaderera vhoriyamu (hypovolemia)
Yakawedzera ropa pH (metabolic alkalosis)
Nzeve kukuvara (ototoxicity) uye kurasikirwa kwekunzwa
Kuderera kana kurasikirwa kwehuropi hunoshanda nekuda kwechiropa kusagadzikana (hepatic encephalopathy) mune vanhu vane chirwere chechiropa
Kuzvimba kwepancreas ( chirwatata )
Jaundice
Zvinetso zveropa zvinosanganisira anemia, aplastic anemia, hemolytic anemia, agranulocytosis, eosinophilia, thrombocytopenia, uye leukopenia
Kuwedzera kweanogadzirisika akadai seanaphylaxis, kukanganisa kwakanyanya kweganda, uye kuzvimba tsinga dzeropa (systemic vasculitis)

Anotora nguva yakareba sei furosemide mhedzisiro?

Mazhinji emhedzisiro yemafurosemide madiki mhedzisiro, sekuwedzera weti kana dambudziko rekugaya, anowana zvirinani sezvo mushonga unopera, kazhinji maawa matanhatu kusvika masere . Mamwe matambudziko akadai sekushomeka kwemvura, kusaenzana kwe electrolyte, hyperglycemia, cholesterol yakakwidziridzwa, uye kugadzikana kwehutachiona zvinotora nguva yakareba kugadzirisa uye zvingangoda kurapwa.

Zvimwe zvakakomba mhedzisiro senge kurwara kwepascreatitis kana kusagadzikana kweropa kungangoda kurapwa kwechipatara. Kunzwa kurasikirwa uye tinnitus kunogona kudzoserwa kana furosemide yagumiswa, asi inogona kuzove mamiriro ekugara mune vamwe vanhu. Hepatic encephalopathy ndeye inogona kutyisidzira hupenyu mhedzisiro mhedzisiro iyo inoda kurapwa uye inopfuurira kune avhareji ye Maawa makumi mana nemasere . Hepatic encephalopathy ndeye inodzoserwa mamiriro, asi iyo yekupona iri pasi.

Furosemide zvinopesana & yambiro

Furosemide inogona kunge isingakodzere munhu wese. Kushandisa zvisirizvo, kuwandisa, uye shanduko mune aripo mamiriro ezvehutano zvese zvikonzero mukugadza kuchengetedzeka kwemushonga uyu.

Kushungurudzwa uye kuvimba

Furosemide haina kukonzera kutsamira panyama kana nepfungwa. Furosemide inogona, zvisinei, inokonzeresa zvenguva pfupi ekurega zviratidzo kana yarega. Furosemide inoshandura muviri wehormonal mashandiro ekugadzirisa weti (diuresis), inonzi renin-angiotensin-aldosterone system, kana RAAS. Kana furosemide ikatorwa pamusoro penguva refu uye nekukasira ikamiswa, muviri unowedzera nekuchengetedza mvura yakawanda uye munyu, zvichikonzera kuyerera kwemvura kana BP . Mhedzisiro yacho inopera mumazuva mashoma, asi vanhu vane chirwere chakakomba chemwoyo vangangoda kuongororwa panguva ino.

Ovhadhozi

Iyo furosemide overdose inokonzeresa kukurumidza diuresis (kubviswa kwemvura) zvichikonzera kushaya mvura uye kupera simba kwe electrolyte. Zviratidzo zvinosanganisira kunyanyisa nyota, kunzwa kupisa, kushaya simba, kudikitira, kana kupera simba. Kuwedzeredza kunowedzerawo njodzi yekurasikirwa kwekunzwa. Kana ovhadhozi inofungidzirwa, enda pakarepo kuchimbichimbi kamuri.

Kurambidzwa

Furosemide ndeye FDA-inogamuchirwa kuti ishandiswe mune vanhu vakasiyana siyana, kubva kune vacheche vasati vazvarwa kusvika kuvanhu vezera rezera. Nekuda kwekukwanisa kushaya mvura uye kupera simba kwe electrolyte, munhu wese anotora furosemide anozotariswa huwandu hwemvura uye huwandu hwemagetsi. Anopa hutano anodzidzisa varwere zviratidzo zvekushayikwa nemvura kana kupera kwemagetsi. Potassium inowedzera inogona kukurudzirwa kudzivirira yakaderera ropa potasium (hypokalemia).

Furosemide haina kumbopihwa vanhu:

Une itsvo dzisingaburitse weti (anuria)
Ndivanaani vakave neakanyanya kukanganiswa nemushonga

Furosemide inoshandiswa nehungwaru kune mamwe mazera emakore kana mamiriro ekurapa:

Vachangoberekwa vacheche ingangoda kuongororwa nekuda kwenjodzi ye itsvo matombo (nephrolithiasis) kana calcium deposits muitsvo (nephrocalcinosis).
Vanhu vakura kupfuura makumi matanhatu nemashanu inogona kutanga pamutero wepasi nepasi uye kuongororwa nguva dzose.
Vanhu vane nhoroondo yemoyo arrhythmias vanofanirwa kuongororwa.
Vanhu vane matambudziko eitsvo (kukanganiswa kweitsvo) kana matambudziko echiropa inogona kupihwa madosi madiki uye kuongororwa nguva zhinji.
Vanhu vane matambudziko ekuchengetedza weti Unogona kuona zviratidzo zvavo zvichiwedzera nekuda kwekuwedzera kweuwandu weti weti mudundira.
Furosemide inogona kunge isinganyanyoita uye inogona kukonzera kurasikirwa kwekunzwa muvanhu vane nephrotic chirwere .
Vanhu vane chirwere cheshuga achanyeverwa pamusoro pekugona kuwedzera kweshuga yeropa. Ivo vanogona kukumbirwa kuongorora mashuga eropa nguva dzose.
Vanhu vane gout vanogona kuona zviratidzo zvavo zvichiwedzera. Uric acid mazinga muropa angangoda kuongororwa.
Furosemide inogona kumisa kana kuwedzera lupus .

Furosemide haisati yakatemwa seyakachengeteka kutora panguva yekuzvitakura kana kuyamwa. Vanachiremba vanorayirwa kuti vanyatsoongorora kukura kwechibereko muvakadzi vanotora furosemide. Kuchenjerera kunodikanwa zvakare kana uchitora furosemide uchiyamwisa. Furosemide ese anopinda mumukaka wemukaka uye anoderedza lactation. Muzviitiko zvese, chiremba anonyatsorondedzera njodzi uye zvakanakira kutora furosemide paunenge uine pamuviri kana mukoti.

Furosemide kudyidzana

Mimwe mishonga yemishonga uye inopfuura-the-counter (OTC) zvinodhaka zvine kudyidzana kwakakura nefurosemide. Chiremba, wemishonga, kana mupi wezvehutano anozove anonyatsoziva mukudyidzana kwezvinodhaka izvi uye nekukwanisa kugadzirira vanhu kusangana kwekuita kwemishonga.

Nekuda kwekudyidzana kwezvinodhaka, furosemide haina kumboshandiswa ne desmopressin kana Marplan (isocarboxazid). Kubatanidza furosemide ne desmopressin kunogona kukonzeresa zvine njodzi sosiamu, nepo isocarboxazid uye furosemide zvingakonzera kuderera kweropa kune ngozi.

Kumwe kudyidzana kwezvinodhaka kunoda kungwarira uye kunyatso tarisisa. Iyi mishonga inosanganisira:

Laxatives, corticosteroids, proton-pump inhibitors, uye bronchodilators (beta-2 agonists): Kubatanidza furosemide nechero ipi yemishonga iyi kunosimudzira njodzi yekushaya mvura uye kusaenzana kwemagetsi.
Aminoglycoside mishonga inorwisa mabhakitiriya: Kubatanidza furosemide nemamwe ototoxic zvinodhaka zvinowedzera njodzi yekukuvara nzeve uye kurasikirwa kwekunzwa.
NSAIDs (nonsteroidal anti-inflammatory drug) uye salicylates
Platinum-based cancer cancer: Kubatanidza furosemide nemishonga senge cisplatin kana carboplatin inowedzera mukana weiyo madhiragi anokuvadza itsvo, mwongo wemabhonzo, kana nzeve.
Ropa kumanikidza zvinodhaka: Kubatanidza furosemide nemamwe madhiragi ayo anoderedza BP anogona kukonzera njodzi yakaderera BP (hypotension).
Antipsychotic, sedatives, barbiturates, opioid, uye erectile dysfunction mishonga: Kubatanidza iyi mishonga ne furosemide kunowedzera njodzi ye hypotension, saka vanhu vane yakaderera BP vangatofanira kugara vachiongororwa kana kuwedzerwa mashandisirwo.

Maitiro ekudzivirira furosemide mhedzisiro

Furosemide inowanzo kupihwa intravenously muzvipatara varwere, asi vanhu vazhinji vanotora mushonga sehwendefa kana mhinduro yemuromo kamwe kana kupfuura pazuva. Iko hakuna muganho pakureba kwenguva furosemide inogona kutorwa, asi vanhu vanogara vachitora furosemide vanofanirwa kutevedzera mashoma matipi ekubatsira kugadzirisa mhedzisiro.

1. Udza chiremba nezvese marapirwo uye mishonga

Pamberi furosemide yakatemwa, udza chiremba anorayira kana nyanzvi yehutano nezve:

Zvese zvazvino mamiriro ekurapa, kunyanya chirwere cheitsvo, chirwere chechiropa, matambudziko ekuti urine (sekuwedzera kweprostate kana kutsemuka kwedundira), gout, lupus, chirwere cheshuga, kusaenzana kwemagetsi
Kubata, kuyamwisa, kana chero zvirongwa zvekubata
Chero ipi inotevera glucose bvunzo yeropa
Chero ipi iri kuuya yekurapa scan iyo inosanganisira radioactive mutsauko madhayi
Chero kuvhiiwa kuri kuuya
Yese OTC uye mishonga yemishonga, zvinowedzera, uye mishonga yemakwenzi iri kutorwa, kunyanya desmopressin kana Marplan (isocarboxazid)

Tora furosemide sekurairwa

Tevedza ese madhairekisheni anonyorerwa tsamba kana kupihwa nachiremba wehutano. Usatora zvakawanda kana zvishoma pane zvakatemwa kusvikira wabvunza chiremba kana nyanzvi yehutano.

3. Dzivisa kupera mvura mumuviri kana kudzikira pamaelectrolyte

Furosemide inogona kukonzera mvura uye ma electrolyte mumuviri kudonha zvakanyanya. Kunyanya kushomeka kwemvura kunogona kukonzera itsvo kukuvara uye kutenderera kweropa. Electrolyte kupera kunogona kukwira kuita matambudziko akakomba kusanganisira coma, kufenda, uye chirwere chemwoyo. Kumbira nyanzvi yezvehutano kuti yakawanda sei uye mhando ipi yemvura inogona kutorwa mushure meiyo furosemide. Potassium kana zvimwe zvinowedzera zvinogona kudikanwa.

Paunenge uchitora furosemide, tarisa zviratidzo zvekushomeka kwemvura zvakaita semuromo wakaoma, maziso akaoma, kurwadza kwemhasuru, kurwadziwa kwemhasuru, kurara, kuneta uye kushaya simba. Unogona kukwanisa kunwa zvinwiwa kugadzirisa dambudziko, asi kana zvinwiwa zvikatadziswa, fonera nyanzvi yehutano kuti ubatsirwe nachiremba.

4. Ongorora mhedzisiro

Vamwe vanhu vanogona kubvunzwa kuti vaongorore mamiriro avo ekurapa senge BP kana huwandu hweshuga yeropa. Tarisa hunhu uhu nokutendeka uye unyore pasi mune dhayari remishonga. Kana iwo maitiro asina kujairika, fonera chiremba kana mumwe mupi wezvehutano kuti akubatsire.

5. Dzivisa NSAIDs uye laxatives

Kurwadziwa kwakakurumbira-senge aspirin uye ibuprofen kunogona kudzikamisa kushanda kwefurosemide uye kuwedzera njodzi kune itsvo kana kunzwa. Izvi zvinoshandawo kune bismuth subsalicylate , chinhu chinoshanda mu Pepto-Bismol . Izvo zvine hukama neasprini uye zvinokonzeresa matambudziko akafanana kana zvabatanidzwa ne furosemide.

Laxatives inowedzera kurasikirwa nemvura, saka inowedzera njodzi yekushaya mvura, kupera kwemagetsi, uye kukuvara kweitsvo kana uchitora furosemide. Taura nachiremba kana imwe nyanzvi yehutano usati watora chero eaya maOTC zvinodhaka uchitora furosemide.

6. Simuka zvishoma nezvishoma

Kana kumira kuchikonzera dzungu, edza kumira zvishoma nezvishoma. Dzungu rinogona kuda kugara pasi kwechinguva. Rara pasi kana dzungu rikanyanya kushata.