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Omeprazole mhedzisiro uye maitiro ekuzvidzivirira

Zvinodhaka Info

Omeprazole (zita rekuti Prilosec) mushonga uye wepamusoro-the-counter mishonga inoderedza acidity yemudumbu. Kuva mumhuri yemishonga inonzi proton pump inhibitors, omeprazole inodzivirira kugona kwemudumbu kuburitsa acid. Kazhinji kazhinji inotorwa sekapsule kana piritsi, omeprazole inoshandiswa kurapa chirungurira , chiratidzo chegastroesophageal Reflux chirwere ( GERD ), kuputika kwesophagitis, gastric ulcers, duodenal ulcers, Helicobacter pylori hutachiona hwemudumbu, uye zvisingawanzo mamiriro ezvehutano akadai seZollinger-Ellison syndrome inokonzeresa kugadzirwa kwemudumbu acid.

Kunyangwe omeprazole inogona kutengwa pasina mushonga, mushonga unemimwe mhedzisiro, zvimwe zvakakomba. Kuongorora kwakazara kwemhedzisiro, yambiro, zvinopesana, uye kudyidzana kwezvinodhaka zvinogona kubatsira kuona kana omeprazole iri mishonga chaiyo yekutora.

RELATED: Dzidza zvakawanda nezve omeprazole | Tora omeprazole discounts

Zvakajairika mhedzisiro mhedzisiro ye omeprazole

Mhedzisiro inowanzoitika yemhedzisiro ye omeprazole ndeiyi:

Kutemwa nemusoro
Marwadzo emudumbu
Nausea
Manyoka
Kusvipa
Kubata ropa
Utachiona hwepamusoro hwekufema
Kuzvimbirwa

Omeprazole dzimwe nguva inosanganiswa nemishonga inorwisa mabhakitiriya clarithromycin uye amoxicillin kurapa hutachiona hweH pylori hwemudumbu, hutachiona hunosanganisirwa negastritis (kutsamwa kwemudumbu) uye ulcer kuumbwa. Kana zvabatanidzwa nemishonga iyi inorwisa mabhakitiriya, mhedzisiro inowanzoitika omeprazole mubatanidzwa wemishonga ndeiyi:

Manyoka
Edza shanduko
Kutemwa nemusoro
Rurimi kushanduka
Kuzara kwemhino

Yakakomba mhedzisiro mhedzisiro ye omeprazole

Matambudziko akakomba haawanzo kuwanikwa omeprazole uye anosanganisira:

Clostridium hutachiona hwakaoma: C. difficile ndiko hutachiona hutachiona hwekoloni hunokonzera manyoka akakomba nefivha.
Chiropa chirwere: Omeprazole inogona kushandura chiropa kushanda uye dzimwe nguva inotungamira kuchiropa chirwere, kufa kwechiropa matishu, kana inogona kuuraya chiropa kutadza.
Lupus: Omeprazole inogona kukonzera kutanga kana kuwedzera kwe lupus erythematosus, iyo autoimmune mamiriro anoonekwa nekuputika uye kutsvuka kweganda.
Allergic maitiro: Hypersensitivity reaction inogona kuve yakapfava kusvika kune yakaoma inosanganisira anaphylaxis, kukurumidza kuzvimba kweganda (angioedema), kukuvara kweganda kwakakomba, kunetseka kufema, uye kuzvimba muitsvo filtration machubhu (interstitial nephritis).

Mimwe mhedzisiro yakaipa inosanganisirwa nekushandisa kwenguva refu kwe omeprazole. Nekuda kweizvi, iyo yekumisikidza ruzivo inotaura kuti omeprazole inofanira kushandiswa pane yakaderera inoshanda dosi kwenguva ipfupi yenguva. Izvi zvinogona kusanganisira:

Bone kutsemuka : Ichishandiswa zvisingagumi, omeprazole inoderedza calcium muropa nekudzikisa kugaya kwekudyiwa kweiyo calcium. Muviri unoyera kurasikirwa uku nekudhonza calcium kubva mumapfupa, zvichitungamira ku osteoporosis uye nenjodzi yakawedzera yekutyoka. Varwere vanotora omeprazole vachienderera mberi pamusoro penguva yakareba (gore rimwe chete kana kupfuura) vanogona kurairwa kutora macalcium ekuwedzera uye / kana mushonga wemishonga kubatsira kudzivirira osteoporosis uye kudzikira kwengozi yekutyoka.
Kukura : Omeprazole yave ichibatanidzwa pamwe nekuvandudzwa kwe gastric fundic gland polyps, zvinowanzo kuve zvine hutachiona pamwe chete nedumbu. Zvakanyanya kunyanya asi zvisingawanzoitika, omeprazole yakave zvakare ichibatanidzwa nemamota anononoka kukura (carcinoids) mune duodenum, chikamu chekutanga chemukati mudumbu, mune varwere vane Zollinger-Ellision syndrome.
Yakaderera magnesium : Yakareba-nguva omeprazole kushandiswa kunogona zvakare kudzikisa magnesium mazinga mumuviri. Low magnesium (hypomagnesemia) inotungamira kune akati wandei kusvika kune zvakakomba mhedzisiro inosanganisira yemwoyo mutinhimira matambudziko kana kubatwa.
Atrophic gastritis uye yakaderera vhitamini B - 12 : Kugara omeprazole kushandiswa kunogona zvakare kukonzera atrophic gastritis (kuzvimba uye kutsamwa kwemudumbu wakadzika). Atrophic gastritis inotungamira kukushomeka kwevhitamini B-12, mamiriro anozopedzisira akonzera kupererwa neropa (kushomeka kwemasero matsvuku eropa). Nokufamba kwenguva, atrophic gastritis inoparadza mudumbu uye inomutsa njodzi yekenza yemudumbu.
Kurera huremu : Kushandiswa kwenguva refu kwe omeprazole kunowedzera njodzi yekuwedzera uremu kune varwere vane GERD.

Omeprazole uye kuwedzera uremu

Kukosha kwehuremu kwakabatana neyakareba-makore kushandiswa kwe omeprazole uye mamwe maPPI (proton pump inhibitors) kurapa chirungurira kana zviratidzo zveGERD. Zvikonzero zvacho hazvina kujeka asi zvinofungidzirwa kuti zvinogona kunge zviri nekuda kwekuwedzera kwekudya chikafu kana zviratidzo zvadzorwa zviri nani. Ramba uchifunga kuti omeprazole inongotarisirwa kurapwa kwenguva pfupi kwechirungurira, GERD, uye mamwe mamiriro emudumbu. Yekushandisa-kwenguva refu inongokurudzirwa chete kune vanhu vane zvisingawanzo mamiriro ehutano ayo anokonzera hypersecretion yemudumbu asidhi. Kana kuora moyo kana GERD kuchida kurapwa kwenguva refu omeprazole, taura nachiremba wezvehutano nezve mamwe madhiragi, chikafu, kana sarudzo yemararamiro ekugadzirisa zvirinani.

Omeprazole nekenza

Iko kune yakakurumbira pfungwa yekuti omeprazole uye mamwe maPPI anogona kuwedzera njodzi yekenza yemudumbu. Tsvagurudzo pamubatanidzwa we omeprazole nekenza yemudumbu yakavhenganiswa. Zvimwe zvidzidzo kuratidza omeprazole (kana chero PPI) kunogona kuwedzera njodzi yekenza yemudumbu. Omeprazole inosimudza njodzi yeatrophic gastritis, kana kutsamwa uye kuzvimba kwemudumbu. Atrophic gastritis inoonekwa semberi yekenza yemudumbu.

Zvinotonyanya kukosha, omeprazole inogona kuvhara zviratidzo zvekenza yemudumbu. Izvi zvakakosha zvikuru. Vanhu vanogona kutanga kutora omeprazole yechirungurira, asi zviratidzo zvinogona kukonzerwa nehutachiona. Zviratidzo zvakadai sekurwadzisa kwechimbichimbi kazhinji zvinofanirwa kuongororwa nemupi wezvehutano.

Inguva yakareba sei omeprazole mhedzisiro mhedzisiro?

Muviri unobvisa omeprazole mumaawa mashoma, mhedzisiro yakawanda inozopera panguva iyoyo. Nekuti mhedzisiro ye omeprazole padumbu mudumbu, zvisinei, kazhinji inogara kwemazuva matatu kana anopfuura, mamwe emudumbu mhedzisiro mhedzisiro inogona kuramba kwemazuva mashoma mushure mekumisa omeprazole. Mhedzisiro inokonzereswa nekubatanidza omeprazole nemishonga inorwisa mabhakitiriya, senge kukanganiswa kwekuravira kana kushanduka kwerurimi, ichagadzirisa mazuva mashoma mushure mekunge maantibayoti amiswa. Yakakomba mhedzisiro mhedzisiro inosangana ne omeprazole, zvisinei, sekurasikirwa kwepfupa, yakaderera chena yeropa masero kuverenga, chirwere chechiropa, kana matambudziko eitsvo, zvinogona kutora nguva yakareba kugadzirisa. Mhan'ara mhedzisiro kumubatsiri wako wehutano.

Omeprazole contraindications & yambiro

Omeprazole uye imwe proton pump inhibitors mishonga inoshanda uye ine yakaderera zviitiko zvemhedzisiro kana ichishandiswa munguva pfupi-pfupi. Nekudaro, omeprazole inogona kunge isiri yemunhu wese, kunyanya kana ichishandiswa pamusoro penguva refu.

Kuvimbika

Kugara uchishandisa omeprazole kunogona kutungamira kune zvakakomba uye kunetesa mhedzisiro. Kunyanya, vanhu vanotora omeprazole kwenguva yakareba vachakura rudzi rwekutsamira panyama . Omeprazole inogadzira mhinduro loop mudumbu. Mushure mekushandisa kusingaperi kwe omeprazole, mudumbu unotanga kuwedzeredza dumbu acid. Kune vanhu vazhinji, kurega kushandisa kwenguva refu omeprazole zvinoreva kudzoka nekukurumidza kweacid reflux uye chirungurira.

Allergies

Omeprazole haifanire kutorwa nemunhu chero ane hypersensitivity kune omeprazole kana chero chinhu chisina basa mumushonga.

Vanhu vane matambudziko echiropa

Omeprazole ndizvo inogadziriswa nechiropa . Varwere vane matambudziko echiropa vanogona kutora omeprazole (kana ichibvumidzwa nachiremba wako), asi muyero unogona kunge uri mudiki pane zvakajairwa.

Vanhu verudzi rweAsia

Vanhu verudzi rweAsia vane njodzi yekuwedzera kuora mwoyo kubva proton pump inhibitors senge omeprazole. Kuenzaniswa nevamwe vanhu, a yakakwira muzana maAsia gaya omeprazole zvishoma nezvishoma - 20% zvichienzaniswa neinenge 3%.Iyo yekumisikidza ruzivo rwe omeprazole inokurudzira yakaderera dosi mune ava varwere.

Vana

Chinyorwa omeprazole inogamuchirwa kurapa GERD zviratidzo uye erosive esophagitis muvana vari pakati pemakore 1 ne16 . Over-the-pakaunda omeprazole haisi , saka haifanirwe kupihwa vana. Kana iyo yekuumbwa kwemvura (mapaketi ekumiswa pamuromo) isingawanikwe, mushonga unogona kusanganiswa neyakaunganidzwa chemishonga. Kana, izvo zvirimo muhombodo zvinogona kusanganiswa nepuniki yeapurosiuce uye nekukurumidza ichidyiwa, pamwe negirazi remvura.

Vakuru

Mumakiriniki ekuedzwa , omeprazole yaive nechengetedzo imwechete muvakuru vakuru sezvazvinoita kune vamwe vakuru.

Kubata uye kuyamwisa

Iko hakuna kumwe kutsvagisisa nezvekuchengetedza kwe omeprazole kushandiswa panguva yekuzvitakura. Ruzivo rwekupa mazano runopa zano kuti vakadzi vane nhumbu vanofanirwa kushandisa omeprazole chete kana zvichinyanya kudikanwa.

Omeprazole inowanikwa mumukaka wemukaka mune zvishoma. Nekuda kwenjodzi dzinogona kuitika kumucheche mwana, iyo FDA inokurudzira kuti vanaamai vatsva vanotora omeprazole vanorega kuyamwisa kana kurega omeprazole.

Kuwirirana kweOmeprazole

Kufanana nemishonga yese, omeprazole inopindirana nemimwe mishonga kana zvinhu.

Kazhinji, chikafu hachikanganisi kumunwa kana kushanda kwe omeprazole. Nekudaro, sezvo chinangwa chiri chekudzikisa mudumbu acid, pamwe hazvinzwisisike kutora omeprazole wobva wadya zvekudya zvinowedzeredza dumbu acid kudonhedza senge zvikafu zvinonhuwirira, chikafu chine mafuta, masoda, doro, kana kofi.

Rilpivirine

Mishonga yeHIV rilpivirine inopesana kuti ishandiswe ne omeprazole nekuti omeprazole mhedzisiro padumbu acidity inoderedza kunwa kwemuviri we rilpivirine. Izvi zvakaenzana nekudzikisa muyero we rilpivirine, mushonga unobata HIV / AIDS, chirwere chinogona kuuraya.

Mimwe mishonga iyo isina kunyanyo nyudzwa nemuviri kana ichibatanidzwa ne omeprazole inosanganisira:

Zvakawanda mishonga inorwisa antifungal dzakadai ketoconazole
Mimwe mishonga inorwisa mabhakitiriya dzakadai se amoxicillin uye ampicillin
Mimwe mishonga inorwisa HIV senge atazanavir uye nelfinavir
Mimwe mishonga yegomarara dzakadai erlotinib
Utachiona mahormone
Vamwe iron inowedzera

Omeprazole kudyidzana neropa vatete (anticoagulants)

Omeprazole inopindirana neropa rakatetepa warfarin, uye inogona kukonzera kubuda kweropa zvisina kujairika kana kutofa. Kana iwe uri pane omeprazole uye warfarin, chiremba wako anokucherekedza zvakanyanya uye angangoda kugadzirisa muyero wemishonga yako (s).

Omeprazole zvakare inopindirana nemaantiplatelet agents Plavix (clopidogrel) uye Pletal (cilostazol). Plavix haifanire kutorwa ne omeprazole. Imwe antiplatelet mushonga inofanira kushandiswa. Kana iwe ukatora Pletal ne omeprazole, iyo muyero wePletal unofanirwa kuchinjwa.

Kufambidzana kweOmeprazole kunowedzera mhedzisiro

Omeprazole inosimudza huturu uye njodzi yemhedzisiro yemamwe madhiragi emushonga nekuwedzera kuwedzerwa kwavo kana kudzikisira metabolism yemuviri wechirwere. Iyi mishonga inosanganisira:

Iyo immune-inodzvinyirira zvinodhaka methotrexate uye tacrolimus
ADHD mishonga
Benzodiazepines akadai diazepam
Mamwe maanticonvulsants zvakadai se phenytoin uye fosphenytoin
Mushonga weHIV saquinavir
Mushonga wemwoyo digoxin

Iyi mishonga inogona kutorwa pamwe ne omeprazole, asi nyanzvi yehutano ingangoda kuongorora kurapa uye kudzikisa madosi kana zvichidikanwa.

Mimwe mishonga inowedzera mukana we omeprazole mhedzisiro kana maviri akatorwa pamwechete. Izvi zvinosanganisira:

Mimwe cystic fibrosis zvinodhaka
Cannabidiol
Iyo antifungal drug voriconazole

Kuwirirana kweOmeprazole kunoderedza kushanda

Mimwe mishonga inomhanyisa metabolism yemuviri we omeprazole, ichideredza kushanda kwayo. Izvi zvinosanganisira:

Iyo mishonga inorwisa mabhakitiriya rifampin, rifapentine, uye rifabutin
Dzimwe mhando dze anticonvulsant zvinodhaka
Dzimwe mhando dze antiviral zvinodhaka senge ritonavir
Barbiturates dzakadai sebutalbital uye phenobarbital
Cystic fibrosis zvinodhaka lumacaftor / ivacaftor
Wort St.

Omeprazole kudyidzana ne diuretics (mapiritsi emvura)

Kutora diuretics ne omeprazole kunosimudzira njodzi ye low magnesium. Therapy ingangoda kuongororwa kana kuchinjwa.

Maitiro ekudzivirira omeprazole mhedzisiro

Kana inotorwa sekurairwa kwenguva shoma, omeprazole ine mashoma mhedzisiro. Matipi mashoma anogona kubatsira kuchengetedza mhedzisiro padiki.

1. Tora omeprazole sekurairwa

Tora muyero wezuva nezuva sekurairwa panguva yakatarwa. Over-the-counter omeprazole inofanira kutorwa mangwanani usati wadya kudya kwemangwanani. Pamushonga omeprazole, chiremba anonyora kana mumwe nyanzvi yezvehutano anotsanangura nguva yezuva yekutora mushonga. Usawedzere kana kudzikisa dosi. Usasvetuke muyero wezuva rimwe kana maviri kana kutora dhivhosi yakapetwa panzvimbo yedosi rakarasika. Mushonga unofanirwa kutorwa zuva nezuva pamusoro penguva izere kuti uone mabhenefiti azere.

2. Dzivisa kutora omeprazole kwenguva refu

Ingotora omeprazole kwenguva pfupi, chero kubva pamazuva gumi kusvika kumavhiki masere. Hushoma kwazvo mamiriro ekurapa anoda kuti omeprazole itorwe kwenguva yakareba. Kuenderera mberi kwekushandisa omeprazole hakungorere chete njodzi yemhedzisiro, asi zvakare kunowedzera njodzi yemamwe mhedzisiro. Kana mushonga wacho uchiita seunoda kushandiswa kwenguva yakareba, taura nemubatsiri wezvehutano nezve dzimwe nzira dzokurapa.

3. Udza chiremba wako nezvese mamiriro ako ekurapa nemishonga

Nekuda kwenjodzi yemhedzisiro, iwe unofanirwa kutaurira chiremba wako nezve:

Chero mamiriro epanyama aungave uine, kunyanya
- Kurwadziwa pachifuva
- Nausea, kurutsa, kurwadziwa nemudumbu, kana kusanzwisisika kuonda
- Kuputika kweganda, kuneta, kana kurwadziwa pamwe chete
- Low magnesium nhanho
- Zvinetso zvechiropa
- Kubata kana kuyamwisa
Yese mishonga yauri kutora parizvino, kunyanya
- Rilpivirine
- Ropa rakapfava / antiplatelets
- Methotrexate kana
- Rifampin
All over-the-counter mishonga uye zvinowedzera zvaunotora, kunyanya
- Wort St.

4. Taura nenyanzvi yezvehutano usati watora OTC omeprazole

Omeprazole inogona kutengwa zviri nyore pasina mushonga. Zvakadaro, nekuda kwenjodzi yekunyanyisa kushandiswa, kutsamira panyama, uye mhedzisiro, tsvaga kuraira kubva kuna chiremba wezvehutano usati watora omeprazole. Panogona kunge paine dzimwe nzira dziri nani dzinosanganisira mimwe mishonga, chinja dhayeti, uye mararamiro maringe

5. Tora omeprazole maminitsi makumi matatu kusvika makumi matanhatu usati wadya

Mikana ndeyekunyorerwa nachiremba, gwara remishonga, kana pasuru ichave nemirairo inoverengwa, Tora usati wadya. Muitiro wakajairika kutora omeprazole Maminitsi makumi matatu kusvika makumi matanhatu usati wadya.

6. Dzivisa kudya kunowedzera asidi uye zvinodhaka

Zvikafu zvakawanda kana zvinodhaka zvinomutsira mudumbu mbichana kuti iwedzere kugadzirwa kweasidhi. Izvi zvinosanganisira chikafu chinonaka, chikafu chakakangwa, nyama ine mafuta, cheeses, mhiripiri, michero yemucitrus, chokoreti, kofi, doro, soda pop, aspirin, peppermint, uye mamwe mamineral anowedzera. Kudya zvinwiwa zvinwiwa uye kutora omeprazole hakuwedzere njodzi ye omeprazole mhedzisiro, zvisinei, zvichawedzera huwandu hweacid mudumbu, kukanganisa maitiro emushonga.