Viibryd vs. Lexapro: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwemishonga & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Viibryd (vilazodone) uye Lexapro (escitalopram) mazita ekurapa zvinodhaka zvinoshandiswa kurapa kushushikana kukuru kwekushushikana (MDD). Zvese zvinodhaka zvinogona kubatsira kubata zviratidzo zvekuora mwoyo, izvo zvinogona kusanganisira manzwiro akareba ekusuwa, kupera kwesimba, uye kurara shanduko. Viibryd kana Lexapro inogona kupihwa mushure mekuongororwa kwechiremba nemupi wezvehutano anonyanya kugadzirisa chirwere chepfungwa.
Vese Viibryd neLexapro mishonga yekudzvinyirira iyo inonyanya kushanda kuwedzera chiitiko che serotonin muuropi. Serotonin ikemikari yeurotransmitter iyo inofungidzirwa kuti inoita basa rakakosha mumanzwiro uye nemanzwiro ehupenyu hwakanaka. Viibryd neLexapro vanoshanda se serotonin reuptake inhibitors (SSRIs), iyo inobatsira kuwedzera huwandu hweserotonin muuropi.
Kunyangwe zvese zviri zviviri zvinodhaka zvinogona kushandiswa kurapa kushushikana, zvine misiyano pamashandisirwo uye mashandiro avanoshanda.
Ndeupi mutsauko mukuru pakati peViibryd neLexapro?
Viibryd
Viibryd izita rechiratidzo che vilazodone. Pakutanga yakagamuchirwa neKudya neDrug Administration (FDA) muna2011 kurapa kushushikana kukuru. Ikozvino hapana generic vhezheni inowanikwa pamusika. Pamusoro pekusarudzwa seSSRI, Viibryd iriwo chikamu che5-HT1A receptor agonist.
Viibryd inouya se10 mg, 20 mg, uye 40 mg piritsi remuromo rinotorwa kamwe chete zuva nezuva nechikafu. Viibryd inogona kusashanda futi kana ikasatorwa nechikafu. Inosvika pakakwirira muropa mushure memaawa mashanu uye ine hafu yehupenyu hwe anenge maawa makumi maviri nemashanu .
Lexapro
Lexapro ndiro zita rekuti escitalopram. Yaive FDA yakatenderwa muna 2002 kurapa MDD mune vese vakuru uye vachiri kuyaruka vane makore gumi nemaviri kusvika gumi nemanomwe. Mukuwedzera pakuora mwoyo, Lexapro inogona kubata chirwere chekuzvidya mwoyo. Shanduro dzeGeneric dzeLexapro dzinowanikwawo pamusika.
Lexapro inogona kutorwa sehwendefa remuromo musimba re5 mg, 10 mg, kana 20 mg. Inowanzo kutorwa kamwe chete zuva nezuva kana kana pasina chikafu. Lexapro inosvika pakakwirira muropa mukati maawa mashanu uye ine hafu yeupenyu kusvika maawa makumi matatu nemaviri .
| Misiyano mikuru pakati peViibryd neLexapro | ||
|---|---|---|
| Viibryd | Lexapro | |
| Kirasi yemishonga | Inosarudza Serotonin Reuptake Inhibitor (SSRI) Chikamu 5-HT1A agonist | Inosarudza Serotonin Reuptake Inhibitor (SSRI) |
| Brand / generic chinzvimbo | Hapana generic vhezheni iripo | Brand uye generic vhezheni iripo |
| Chii chinonzi generic zita? | Vilazodone | Escitalopram |
| Ndeapi mafomu (s) ayo mushonga unouya? | Hwendefa remuromo | Hwendefa remuromo |
| Ndeipi muyero wakajairwa? | 20 mg kamwe pazuva | 20 mg kamwe pazuva |
| Yakareba sei iyo yekurapa? | Nguva refu | Nguva refu |
| Ndiani anowanzoshandisa mushonga? | Vakuru | Vakuru nevechiri kuyaruka |
Mamiriro ezvinhu akarapwa naViibryd naLexapro
Viibryd neLexapro ndeye FDA-inogamuchirwa antidepressants ayo anoshandiswa kurapa kwakanyanya kushushikana kwepfungwa. Chero mushonga unogona kupihwa mukubatana ne psychotherapy uye shanduko yemararamiro kubatsira kudzikisira zviratidzo zvekuora mwoyo.
Lexapro zvakare FDA inogamuchirwa kurapa zvakajairika kusagadzikana kusagadzikana (GAD). Kunyangwe isina kubvumidzwa kunetseka, Viibryd yakadzidzwa mumakiriniki ekuedzwa yekurapa kushushikana. Viibryd kana Lexapro dzimwe nguva inogona kushandiswa kure-chitambi kurapa obsessive-kumanikidza kusagadzikana (OCD).
| Mamiriro | Viibryd | Lexapro |
| Huru kushungurudzika kusagadzikana | Ehe | Ehe |
| Chirwere chekuzvidya mwoyo | Kunze-chitaridzi | Ehe |
| Kutarisa-kumanikidza kusagadzikana | Kunze-chitaridzi | Kunze-chitaridzi |
Viibryd kana Lexapro inoshanda zvakanyanya here?
Mune imwe yakasarudzika, kliniki kuyedzwa, vilazodone uye escitalopram vakafananidzwa musoro-kumusoro-pakati pemuenzaniso wevarwere ve50. Hamilton Kuzvidya Mwoyo Scale (HAM-A) uye Hamilton Kushungurudzika Kukoshesa Scale (HAM-D) zvikoro zvakadzikiswa mumapoka ese ekurapa. Nekudaro, escitalopram yakawanikwa ichidzikisa yakazara HAM-A uye HAM-D mamaki kupfuura vilazodone (P<0.0001).
Mukuongorora kwakarongeka, escitalopram yaive uchienzaniswa nemamwe matanhatu anodzvinyirira , inosanganisira fluoxetine, citalopram, uye sertraline. Ichi chidzidzo chakaongorora akawanda meta-ongororo uye ndokuona kuti escitalopram yainyanya kushanda uye kudzikisira kushushikana zviratidzo nekukurumidza kupfuura mamwe maSSRI.
Inofananidzwa ne placebo, kana pasina kurapwa, Viibryd neLexapro ndiwo maitiro anoshanda ekurapa kushushikana. Zvisinei, misiyano yemabatiro anoita munhu inogona kutora chinzvimbo chakakosha mukuita kwekudzvinyirira. Naizvozvo, zvakakosha kubvunza kune wehutano mupi wezano rekurapa kana uchitanga kana kuchinjira kune mutsva wekudzvinyirira .
Kuvhavha uye mutengo kuenzanisa kweViibryd vs. Lexapro
Viibryd inongowanikwa chete sezita-zita mishonga. Neichi chikonzero, inogona kunge iri nzira inodhura ichienzaniswa nemamwe madhiragi ekudzvinyirira. Mamwe maMedare uye zvirongwa zveinishuwarenzi zvinogona kuvhara Viibryd. Mari yepakati yemari yeViibryd iri madhora mazana matatu nemakumi mapfumbamwe nemapfumbamwe. Kushandisa CouponCare Viibryd coupon kunogona kudzikisa mutengo kusvika pamadhora mazana maviri nemakumi masere nemasere mafarmacy.
Lexapro inowanikwa sezita-zita uye generic mishonga. Kuenzaniswa neViibryd, iri sarudzo isingadhuri. Iyo yakafukidzwawo neakawanda Medicare uye zvirongwa zveinishuwarenzi. Ivhareji yemari mutengo wegeneral Lexapro iri kutenderera $ 177. Nekadhi rakaderera kubva kuSingleCare, unogona kuwana generic kweinenge $ 15.
| Viibryd | Lexapro | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Zvakawanda | 20 mg kamwe chete pazuva (huwandu hwemapiritsi e30) | 20 mg kamwe chete pazuva (huwandu hwemapiritsi e30) |
| Chaizvoizvo Medicare copay | $ 1– $ 11 | $ 0– $ 30 |
| SingleCare mutengo | $ 278 + | $ 15 + |
Zvakajairika mhedzisiro mhedzisiro yeViibryd vs. Lexapro
Mhedzisiro inowanzoitika yeViibryd manyoka, kusvotwa, kuoma muromo, kutemwa nemusoro, uye kuwedzera kudikitira. Zvimwe zvinokonzeresa mhedzisiro zvinosanganisira dzungu, kurara, kushaya hope, uye marwadzo akabatana (arthralgia), pakati pevamwe.
Mhedzisiro inowanzoitika yeLexapro kushungurudzika, kutemwa nemusoro, manyoka, kuwedzera kudikitira, uye kuoma muromo. Zvimwe zvinogona kuitika mhedzisiro yeLexapro inogona kusanganisira kuvharirwa uye nezviratidzo zvehururu.
Viibryd uye Lexapro, semamwe mishonga yekudzvinyirira , inogona kukonzera shanduko mukuda kudya. Izvi zvinogona kutungamira mukurema kana kurema kwevamwe vanhu.
Vaviri Viibryd naLexapro zvinogona zvakare kukonzera bonde mhedzisiro . Iko kushandiswa kweanodzvinyirira kunogona kukonzera kudzikira kwepabonde drive (libido). Viibryd uye Lexapro zvinogona zvakare kukonzera kusagadzikana pabonde, senge erectile dysfunction, uye matambudziko ne ejaculation. Nekuti Viibryd inoshandawo sechikamu che5-HT1A receptor agonist, inogona kunge iine njodzi yakaderera yemitezo yepabonde kupfuura Lexapro.
| Viibryd | Lexapro | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Manyoka | Ehe | 26% | Ehe | 8% |
| Kuzvimbirwa | Kwete | - | Ehe | 3% |
| Kuwedzera kudikitira | Ehe | * | Ehe | 5% |
| Nausea | Ehe | 22% | Ehe | gumi neshanu% |
| Muromo wakaoma | Ehe | 8% | Ehe | 6% |
| Kuzvidya mwoyo | Ehe | piri% | Ehe | 3% |
| Zviratidzo zvakaita sefuru | Kwete | - | Ehe | 5% |
| Kutemwa nemusoro | Ehe | gumi neshanu% | Ehe | 24% |
| Dzungu | Ehe | 6% | Ehe | 5% |
| Kukotsira | Ehe | 4% | Ehe | 6% |
| Kusarara | Ehe | 7% | Ehe | 9% |
| Palpitations | Ehe | 1% | Ehe | * |
| Kuwedzera kudya | Ehe | 1% | Ehe | * |
| Kurera huremu | Ehe | 1% | Ehe | * |
| Kuderedza kudya | Ehe | * | Ehe | 3% |
| Joint kurwadziwa | Ehe | piri% | Ehe | * |
| Erectile kusagadzikana | Ehe | 3% | Ehe | 3% |
| Ejaculation kusagadzikana | Ehe | 1% | Ehe | 9% |
| Yakadzikira libido | Ehe | 4% | Ehe | 3% |
* haina kutaurwa
Kakawanda hakubvi pane data kubva kumusoro-kuenda-kumusoro kutongwa. Izvi zvinogona kunge zvisiri runyorwa ruzere rwemhedzisiro mhedzisiro inogona kuitika. Ndokumbira utarise kuna chiremba wako kana mupi wezvehutano kuti udzidze zvimwe.
Kwayaka: DailyMed ( Viibryd ), Zuva Nezuva ( Lexapro )
Kubatana kwezvinodhaka zveViibryd vs. Lexapro
Viibryd uye Lexapro inofanirwa kudzivirirwa painotora monoamine oxidase inhibitors (MAOIs), senge selegiline uye phenelzine. Viibryd kana Lexapro haifanire kutorwa mukati memazuva gumi nemana ekumisa MAOI kana panogona kuve nenjodzi yakawedzera yeserotonin syndrome. Viibryd neLexapro inofanirwawo kudzivirirwa kana kuongororwa nemamwe madhiragi eserotonergic seanodzvinyirira, ayo anogona kuwedzera njodzi yeserotonin syndrome.
Iko kushandiswa kweViibryd kana Lexapro kunofanirwa kuongororwa pachinotora nonsteroidal anti-inflammatory drug (NSAID) kana anticoagulant. Kutora mishonga iyi pamwechete kunogona kuwedzera njodzi yekubuda ropa.
Nekuti Viibryd neLexapro vanonyanya kugadziriswa muchiropa, kunwa kwavo kunogona kukanganiswa nemishonga inoshandura mamwe enzyme echiropa. Mamwe maantifungal uye maantibayoti anogona kuwedzera iwo mazinga eViibryd neLexapro muropa, izvo zvinogona kuwedzera njodzi yemhedzisiro. Mimwe mishonga senge mamwe maanticonvulsants anogona kudzikira huwandu hweropa hweViibryd neLexapro, izvo zvinogona kudzikisira kushanda kwavo kwese.
Lexapro inozivikanwa kuti ingangoita kukonzeresa kwemoyo mutinhimira unonzi QT kuwedzera. Kutora Lexapro nemamwe antipsychotic zvinodhaka seAripiprazole kana quetiapine zvinogona kuwedzera njodzi yekuwedzera kweQT.
| Zvinodhaka | Kirasi yemishonga | Viibryd | Lexapro |
| Selegilin Phenelzine Rasagiline | Monoamine oxidase inhibitors (MAOIs) | Ehe | Ehe |
| Paroxetine Sertraline Fluoxetine | Kusarudza serotonin reuptake inhibitors (SSRIs) | Ehe | Ehe |
| Venlafaxine Desvenlafaxine Duloxetine | Serotonin norepinephrine reuptake inhibitors (SNRIs) | Ehe | Ehe |
| Amitriptyline Clomipramine Nortriptyline | Tricyclic antidepressants (TCAs) | Ehe | Ehe |
| Bupropion | Aminoketone | Ehe | Ehe |
| Buspirone | Anxiolytic | Ehe | Ehe |
| Aspirin Ibuprofen Naproxen Diclofenac | Nonsteroidal anti-anogumbura zvinodhaka (NSAIDs) | Ehe | Ehe |
| Warfarin | Anticoagulants | Ehe | Ehe |
| Digoxin | Cardiac glycoside | Ehe | Ehe |
| Sumatriptan Rizatriptan Eletriptan | Triptans | Ehe | Ehe |
| Ketoconazole Itraconazole | Antifungals | Ehe | Ehe |
| Ritonavir | Protease inhibitors | Ehe | Ehe |
| Clarithromycin | Mishonga inorwisa mabhakitiriya | Ehe | Ehe |
| Carbamazepine Phenytoin | Anticonvulsants | Ehe | Ehe |
| Aripiprazole Clozapine Quetiapine | Antipsychotic | Kwete | Ehe |
Bvunza nyanzvi yezvehutano kune kumwe kudyidzana kwezvinodhaka.
Yambiro dzeViibryd uye Lexapro
Mishonga yekudzvinyirira senge Viibryd kana Lexapro inogona kuwedzera njodzi yekuzviuraya pfungwa, kunyanya kune vechidiki varwere. Vaya vanotora Viibryd kana Lexapro vanofanirwa kuongororwa nekuda kwekuwedzera kushushikana uye pfungwa dzekuzviuraya.
Kusarudza serotonin reuptake inhibitors (SSRIs) ine mikana yekukonzera serotonin syndrome, mamiriro anogona kunge akakomba anoitika kana paine serotonin yakawandisa muuropi. Njodzi inowedzerwa kana mishonga yekudzvinyirira ikatorwa pamwe nemamwe madhiragi eserotonergic. Zviratidzo nezviratidzo zve serotonin syndrome zvinogona kusanganisira kukurumidza kurova kwemoyo, kuwedzerwa kweropa, kudikitira, kudedera, uye fivha.
Vamwe vanhu vanogona kuongororwa nhoroondo yebipolar kusagadzikana vasati vatanga kurapwa neViibryd kana Lexapro. Izvi zvinodzvinyirira zvine mukana wekumisikidza mania kana hypomania kune vamwe vanhu vane bipolar kusagadzikana.
Viibryd neLexapro dzinofanirwa kutapurwa kana kumiswa zvishoma nezvishoma kana zvichidikanwa. Kuregedza nekukurumidza kweanodzvinyirira kunogona kuwedzera njodzi yekubvisa zviratidzo.
Bvunza mupi wezvehutano nezve zvimwe zvinogona kunyeverwa uye matanho.
Inowanzo bvunzwa mibvunzo nezve Viibryd vs. Lexapro
Chii chinonzi Viibryd?
Viibryd izita-zita rekunyorerwa mushonga rinoshandiswa kurapa kwakanyanya kushushikana kwepfungwa (MDD). Ndiro zita rechiratidzo che vilazodone. Viibryd inoshanda senge yakasarudzika serotonin reuptake inhibitor (SSRI) uye yakasarudzika 5-HT1A receptor agonist. Inowanzo kutorwa se 20 mg piritsi kamwe zuva nezuva nechikafu.
Chii chinonzi Lexapro?
Lexapro iri zita rezita-mushonga iro FDA rinogamuchirwa kurapa kwakanyanya kushungurudzika kusagadzikana (MDD). Iyo zvakare inogamuchirwa kurapa zvakajairika kusagadzikana kusagadzikana (GAD). Zita rekuti Lexapro ndiro escitalopram. Lexapro imushonga weSRI inotorwa kamwe chete zuva nezuva.
Viibryd naLexapro vakafanana here?
Viibryd naLexapro vanoshanda nenzira dzakafanana yekurapa mamiriro ehutano hwepfungwa, asi haana kufanana. Viibryd inoshanda seSSRI uye isina kukwana 5-HT1A agonist nepo Lexapro inoshanda zvakanyanya seSSRI. Kunyangwe Viibryd naLexapro vari vaviri vanobvumidzwa kurapa kushushikana kukuru, Lexapro inobvumidzwa kurapa kushushikana.
Viibryd kana Lexapro zvirinani here?
Iyo iri nani antidepressant ndiyo iyo iwe yaunopindura zvakanakira. Viibryd uye Lexapro ese ari maviri anoshanda mushonga mishonga yekuora mwoyo. Kuenzaniswa neLexapro, Viibryd inogona kukonzera mashoma mitezo yepabonde.
Ndinogona here kushandisa Viibryd kana Lexapro ndichiri nepamuviri?
Zvinodzvinyirira senge Viibryd kana Lexapro inogona kuva yakachengeteka kutora uine pamuviri. Nekudaro, hapana humbowo hwekiriniki hwakaringana kuratidza kuti Viibryd kana Lexapro vakachengeteka zvachose kana kuti vane njodzi kutora panguva yekuzvitakura. Iyi mishonga inofanirwa kutorwa chete kana mabhenefiti akakunda njodzi. Bvunza mupi wezvehutano nezvekurapa nezvekutora mishonga yekudzvinyirira uchiri nepamuviri.
Ndinogona here kushandisa Viibryd kana Lexapro nedoro?
Kunwa zvine mwero hakungakonzere chero kukuvara kana wanga uri pakurapa kusingagumi neViibryd kana Lexapro. Nekudaro, kushandisa doro kunogona kuwedzera njodzi yemhedzisiro, sedzungu, kutsimwaira, uye kuvhiringidzika. Bvunza mupi wezvehutano nezve kuchengetedzeka kweanodzvinyirira pavanonwa doro.
Viibryd yakanaka kune kushushikana here?
Chinhu chinoshanda muViibryd, vilazodone, chakave chidzidzo chekurapa kushushikana. Zvinoenderana nemakiriniki ekuedzwa, vilazodone inogona kunge iri inoshanda kurapa sarudzo yeakajairika kunetseka kusagadzikana (GAD). Kutsvaga kwakawanda kunodiwa hazvo. Parizvino, Viibryd haisi FDA inogamuchirwa kurapa kunetseka.
Ndeipi nguva yakanakisa yezuva yekutora Viibryd?
Viibryd inofanirwa kutorwa panguva imwechete mazuva ese. Zvichienderana nemhinduro yemuviri wako kumushonga, zvingave zviri nani kutora Viibryd mangwanani kana manheru. Vazhinji vanachiremba vanokurudzira kutora Viibryd mangwanani nekudya kwekuseni.
Chii chinoitika kana ndikatora Viibryd ndisina chikafu?
Viibryd inogona kunge isingabudirire kana ikatorwa pasina chikafu. Izvi zvinodaro nekuti Viibryd inodhonzwa zvirinani kana ikapihwa pamwe nekudya. Inofananidzwa nekudyiwa kwayo nechikafu, iko kunwiwa kweViibryd pasina chikafu kwakaderera neinenge makumi mashanu% .
