Diuretics: Zvishandiso, zvakajairika zvigadzirwa, uye ruzivo rwekuchengetedza

Zvinodhaka Info

Dhiureti runyorwa | Chii chinonzi diuretics? | Mashandiro avo | Zvishandiso | Mhando | Ndiani anogona kutora diuretics? | Kudzivirirwa | Zvimwe zvinokanganisa | Mariro

Diuretics, inowanzozivikanwa semapiritsi emvura, inowedzera huwandu hwemvura inodzingwa mumuviri kuburikidza neweti. Imwe yeanonyanya kuzivikanwa, echinyakare diuretics ndeye caffeine, inowanzo kuwanikwa mukofi netii. Nekudaro, caffeine ine hunyoro diuretic mhedzisiro uye haiwanzoshandiswa sedhiureti mune ekurapa marongero.

Nhoroondo yemazuva ano ye diuretics yakatanga mukati 1919 apo mudzidzi wekurapa akawana kuti majekiseni ane mercury aishanda pakuburitsa mvura muvarwere vechirwere. Yakanga isiri iyo iyo iyo 1950s nema1960 izvo zvinowanzoiswa thiazides uye loop diuretics zvakawanikwa uye zvakashandiswa zvakanyanya. Nhasi, diuretics inowanzo gadzirirwa kurapa yakakwira BP uye mamwe mamiriro.

Enderera kuverenga kuti udzidze zvakawanda nezve akasiyana marudzi e diuretics, mashandisiro avo, uye mhedzisiro.

Chinyorwa che diuretics
Zita reBrand (zita regeneral)	Avhareji yemari mutengo	SingleCare mutengo	Dzidza ZVIMWE
Microzide (hydrochlorothiazide)	$ 56 pa 30, 25 mg mahwendefa	Tora hydrochlorothiazide coupons	Hydrochlorothiazide ruzivo
Hygroton (chlorthalidone)	$ 31 pa 30, 25 mg mahwendefa	Tora chlorthalidone coupon	Chlorthalidone ruzivo
Lozol (indapamide)	$ 46 pa 30, 2.5 mg mahwendefa	Tora indapamide coupon	Indapamide ruzivo
Zaroxolyn (metolazone)	$ 105 pamakumi matatu, 2.5 mg mahwendefa	Tora metolazone coupon	Metolazone ruzivo
Bumex (bumetanide)	$ 91 pa 30, 1 mg mahwendefa	Tora bumetanide coupons	Bumetanide ruzivo
Lasix (furosemide)	$ 26 pa 30, 20 mg mahwendefa	Tora furosemide coupons	Furosemide ruzivo
Demadex (torsemide)	$ 35 pa 30, 20 mg mahwendefa	Tora torsemide coupons	Torsemide ruzivo
Edecrin (ethacrynic acid)	$ 95 pa 4, 25 mg mahwendefa	Tora ethacrynic acid coupons	Ethacrynic acid ruzivo
Midamor (amiloride)	$ 42 pa 30, 5 mg mahwendefa	Tora amiloride coupons	Amiloride ruzivo
Dyrenium (triamterene)	$ 478 pa 30, 50 mg mahwendefa	Tora triamterene coupons	Triamterene ruzivo
Aldactone (spironolactone)	$ 30 pa30, 25 mg mahwendefa	Tora spironolactone coupons	Spironolactone ruzivo
Inspra (eplerenone)	$ 235 pa 30, 25 mg mapiritsi	Tora eplerenone coupon	Eplerenone ruzivo

Dzimwe diuretics

• Dhiyabhorosi (chlorothiazide)
• Naturaltin (bendroflumethiazide)
• Enduron (methyclothiazide)
• Renese (polythiazide)
• Saluron (hydroflumethiazide)
• Diamox (acetazolamide)
• Daranide (dichlorphenamide)
• Neptazane (methazolamide)
• Diurex (pamabrom)
• Osmitrol (mannitol)

Chii chinonzi diuretics?

Zvikasadaro inozivikanwa semapiritsi emvura, diuretiki mishonga inowedzera huwandu hwemunyu nemvura yakaburitswa kubva mumuviri. Iyi mishonga inowedzera kugadzirwa kweweti inogadzirwa muitsvo, izvo zvinotungamira mukuwedzera weti kuyerera, kana diuresis. Diuretics inowanzo shandiswa kurapa BP (neBP) uye kuchengetedza kwemvura, kana edema, inova chiratidzo chekutadza kwemoyo, matambudziko eitsvo, uye kutadza kwechiropa. Mamwe diuretics anogona zvakare kushandiswa kurapa kuzvimba muhuropi kunokonzerwa nekukuvara kwakanyanya kwemusoro kana kuzvimba mumaziso anokonzerwa nemamiriro eziso senge glaucoma .

Diuretics inoshanda sei?

Diuretics inoshanda nekushandura muyero wemvura, munyu, uye maelectrolyte mumuviri.

Kunyanya zvakanyanya, zvine mhedzisiro pane akasiyana maitiro muitsvo dzinoita basa mune sodium uye electrolyte reabsorption. Kune akatiwandei akasiyana marudzi e diuretics. Imwe yeayo anogona kushanda munzvimbo dzakasiyana dzeiyo itsvo , iyo yekusefa nhengo yemuviri. Nekuda kwekuwedzera kwekuwedzera kwesodiyamu yakaburitswa kubva muitsvo, mvura yakawanda inoburitswa kunze kwemuviri weti.

Zvinogona kuve zvakakosha kuti unzwisise chimiro cheitsvo uye kuti inoshanda sei kuti unzwisise zvizere kuti diuretics inoshanda sei. Itsvo yega yega ine vanopfuura miriyoni imwe nephrons, ayo ari mafirita efirita anobvisa marara uye anogadzira weti mumuviri. Zvichienderana nerudzi rwe diuretic, iyi mishonga inowanzo shanda mune yakasarudzika yakanyungudutswa tubule, iyo inokwira chikamu chechiuno cheHenle, iyo distal yakasanganiswa tubule, kana iyo yekuunganidza tubule.

Chii chinonzi diuretics chinoshandiswa?

Diuretics inogona kushandiswa kurapa akasiyana mamiriro akasiyana anokanganisa moyo, itsvo, uye chiropa. Izvo zvinoshandiswawo sema antihypertensives kudzikisa BP. Dhiureti dzimwe nguva anoshungurudzwa neavo vane dambudziko rekudya kuitira kuti vadzikire. Diuretics inogona kuwanikwa chete nechinyorwa uye inogona kushandiswa kurapa zvinotevera:

• Kutadza kwemoyo
• Kuruboshwe ventricular kutadza
• Kuwedzera kweropa
• Chakakomba itsvo kutadza
• Oliguric renal kutadza
• Itsvo matombo
• Kukuvara kwetsvo kwakanyanya
• Chirwere cheitsvo
• Chiropa chirwere
• Pulmonary edema
• Yakakwirira mazinga eropa calcium (hypercalcemia)
• Yakakwira mazinga eropa potasium (hyperkalemia)
• Nephrogenic chirwere cheshuga insipidus
• Kumusoro kusingagadzirisike kumanikidza
• Glaucoma

Mhando dze diuretics

Thiazide diuretics

Thiazides inotarisa iyo sodium-chloride cotransporter yekudzorerazve reaborption yesodium, iyo inobatsira kudzora sodium uye kuwanda kweropa mazinga. Sekirasi yemishonga, thiazide diuretics inodzivirira kuitwazve kweinenge 5% ye sodium mune distal inogadziriswa tubule. Thiazides zvakare inodzivirira iyo reabsorption ye potassium, iyo inogona kutungamira mukunyanyisa kubviswa kwe potassium kubva mumuviri. Low potassium mazinga (hypokalemia) inogona kutungamira kune zvisina kujairika moyo mutinhimira, pakati pemamwe matambudziko. Nekuda kwemhedzisiro yavo, thiazides inowanzo shandiswa seyekutanga-kurapwa kurapwa kwehypertension pane ACE inhibitors. Mienzaniso yeiazides inosanganisira Microzide (hydrochlorothiazide) uye Hygroton (chlorthalidone).

Loop diuretics

Kunge thiazides, loop diuretics inobatsirawo kudzora mwero we sodium mune itsvo. Nekudaro, loop diuretics inoshanda munhengo inokwira yeti loop yaHenle muNephron. Iyi mishonga inotarisa iyo sodium-potasium-chloride cotransporter kuvharisa sodium nemvura kudzokororwazve. Loop diuretics inogona zvakare kudzikisa kuiswa kwe potassium, izvo zvinogona kutungamira kune yakaderera potasiamu mumuviri. Loop diuretics inogona kushandiswa kurapa kutadza kwemoyo, itsvo kutadza, mazinga epotassium akawanda (hyperkalemia), yakakwira calcium mazinga (hypercalcemia), uye mhando zhinji dzeedema, senge pulmonary edema. Mienzaniso ye loop diuretics inosanganisira Bumex (bumetanide) uye Lasix (furosemide) , pamwe neDemadex (torsemide).

Potassium-inodzivirira diuretics

Potassium-inodzivirira diuretics haikonzere kuwedzera secretion ye potassium mumugini. Potassium-inodzivirira diuretics senge amiloride inosunga kune chiteshi sodiamu kudzora kudzokororazve kwesodium muropa. Izvi zvinowedzera kurasikirwa kwemvura pasina kudzikisira huwandu hwe potassium. Imwe potasium-inodzivirira diuretics senge spironolactone inoshanda mu distal tubule uye kuunganidza madhiri ekuvhara mhedzisiro yealdosterone, steroid hormone inowedzera sodium reabsorption. Mienzaniso ye potassium-sparing diuretics inosanganisira Midamor (amiloride), Dyrenium (triamterene), Aldactone (spironolactone), uye Inspra (eplerenone).

Carbonic anhydrase inhibitors

Carbonic anhydrase ndiyo enzyme inowanikwa munzvimbo dzakasiyana dzemuviri, kusanganisira masero matsvuku eropa uye proximal yakasanganiswa tubule yeitsvo. Iyi enzyme inobatsira muviri kudzoreredza sodium, bicarbonate, uye chloride. Carbonic anhydrase inhibitors inovhara iyi enzyme kuburitsa zvinhu izvi uye mvura yakawandisa kubva mumuviri. Carbonic anhydrase inhibitors inowanzo shandiswa kurapa glaucoma. Mienzaniso inosanganisira Diamox (acetazolamide) uye Neptazane (methazolamide).

Dzimwe diuretics

Xanthine diuretics rudzi rweiyo yakapfava diuretic iyo inovhara iyo reabsorption yemvura mune yakawedzera tubule yeitsvo. Mienzaniso ye xanthine diuretics inosanganisira caffeine uye Diurex (pamabrom). Osmotic diuretics shandisa maitiro eosmosis kuti utore mvura uye udzikise kuchengetedza kwemvura. Osmotic diuretics inonyanya kushanda mune proximal tubule uye chiuno cheHenle. Imwe inowanzo shandiswa osmotic diuretic ndiOsmitrol (mannitol), iyo inoshandiswa kudzikisira kusagadzikana kwekumanikidza uye kurapa kwakanyanya renal kutadza.

Ndiani anogona kutora diuretics?

Vakuru

Diuretics inowanzo shandiswa kurapa edema uye mamwe mamiriro emwoyo muvanhu vakuru. Iko kushandiswa kwema diuretiki muvakuru kunoenderana nemamiriro ekurapwa.

Vana

Vana vanogona kunyorerwa diuretics kuti vadzikise kuwanda kwemvura inokonzerwa ne congestive moyo kutadza uye renal kutadza. Iko kushandiswa kwema diuretiki muvana kunoenderana nemamiriro ekurapwa. Muyero we diuretics muvana unowanzo kuverengerwa nehuremu hwemuviri.

Ko diuretics yakachengeteka here?

Diuretics kazhinji mishonga yakachengeteka kana ichishandiswa sekurairwa. Nekuda kwemhedzisiro yavo pamvura, munyu, uye electrolyte kudzorerazve, zvinogona kukonzera kusaenzana kwemvura uye electrolyte. Kuwedzeredza kurasikirwa kwemvura kunogona zvakare kukonzera kushaya mvura mune vamwe varwere. Low potasiamu mazinga anogona zvakare kuve kunetsekana neakawanda diuretics kunze kwe potassium-sparing diuretics.

Iko kushandiswa kwakabatana kwe diuretics uye digoxin kana lithiamu inogona kuda kuongororwa kana kudzivirirwa. Taura nemubatsiri wezvehutano nezve kumwe kusangana kwekushandisa zvinodhaka ne diuretics.

Diuretics inoyeuka

Iko hakuna ikozvino diuretic inoyeuka kubva munaKurume 2021.

Kurambidzwa kwedhiureti

Usatore diuretiki kana iwe uine allergies kune izvo zvinoshandiswa mune diuretics. Mimwe diuretics ine sulfa, iyo inogona kukonzeresa kugadzikana mune vanhu vakambosangana nemushonga unorwisa mishonga yesulfonamide se sulfamethoxazole.

Vamwe vanhu vakuru vangangoda kuongororwa vachitora diuretics. Dhiureti inogona kuwedzera njodzi yekuita dzungu kana kuwira kune vanhu vakuru nekuda kwe postural hypotension , kana kukurumidza kudzikira kweropa kana uchichinja pekugara uye pakamira nzvimbo.

Unogona here kutora diuretics uchiine nhumbu kana kuyamwisa?

Diuretics dzimwe nguva inorayirwa panguva yepamuviri yehypertension kana yemoyo mamiriro. Zvisinei, kuchengetedzeka kwavo hakuna kusimbiswa nezvidzidzo. Diuretics inofanira kungoshandiswa chete kana mabhenefiti akakunda njodzi. Kuwedzera kweiyo diuretics kunogona kukanganisa mukaka kupa uye kudzvinyirira lactation mune vakadzi vari kuyamwa. Bvunza mupi wezvehutano nezvekurapa usati washandisa diuretiki paunenge uine pamuviri kana kuyamwa.

Ko diuretics inodzorwa zvinhu here?

Kwete, diuretics haisi zvinhu zvinodzorwa.

Kazhinji diuretics mhedzisiro

Mhedzisiro inowanzoitika yemadhiureti anosanganisira:

• Kakawanda weti
• Dzungu
• Musoro wakareruka
• Kuneta kana kuneta
• Kutemwa nemusoro
• Mapundu
• Tsandanyama tsandanyama
• Manyoka
• Erectile kusagadzikana
• Kuwedzera kweshuga yeropa

Mhedzisiro yakakomba ye diuretics inosanganisira yakaderera potasiamu mazinga, kana hypokalemia, izvo zvinogona kutungamira kune zvisina kujairika moyo mutinhimira. Pasina kurapwa, mashoma potasium mazinga anogona kutungamira kumatambudziko anotyisidzira hupenyu. Potassium-inodzivirira diuretics haigone kukonzeresa iyi mhedzisiro asi inogona kukonzera yakakwira potasiamu mazinga (hyperkalemia). Diuretics inogona kukonzera kumwe kusaenzana kwe electrolyte senge yakaderera sodium mazinga (hyponatremia) uye yakaderera calcium mazinga (hypocalcemia).

Diuretics inogona zvakare kukonzera kupera mvura mumuviri nekuda kwekubuda kwemamwe mvura zhinji. Zviratidzo zvekushayiwa mvura zvinogona kusanganisira nyota yakanyanyisa, kuvhiringidzika, uye weti yakasviba.

Mamwe ma diuretiki akadai setiazide anogona kuwedzera kwenguva pfupi cholesterol mwero.

Udza chiremba wako kana iwe uine nhoroondo yechero yeanotevera mamiriro usati washandisa diuretic:

• Chirwere cheshuga
• Gout
• Zvinetso zveitsvo
• Kupera mvura mumuviri
• Pancreatitis
• Lupus
• Zvinetso zvekuenda kumwedzi

Taura nemubatsiri wezvehutano kuti udzidze nezvezvimwe zvinokanganisa miedzo, yambiro, uye chengetedzo inosanganisirwa ne diuretics

Mariureture yakawanda zvakadii?

Diuretics kazhinji mishonga yakachipa uye inodhura iyo inowanikwa muzita-zita uye generic vhezheni. Anenge ese Medicare uye zvirongwa zveinishuwarenzi zvichafukidza diuretics. Mari dzinogona kusiyana zvichienderana nehurongwa hweinishuwarenzi. Pasina inishuwarenzi, mutengo we diuretiki unosiyana zvichienderana nehuwandu hwemapiritsi akatemwa. Nekudaro, kushandisa kadhi rinodzora kubva kuSingleCare inogona kubatsira kudzikisa mutengo we diuretics.