Tresiba vs. Lantus: Misiyano, kufanana, uye izvo zviri nani kwauri
Zvinodhaka Vs. ShamwariKuongorora kwezvinodhaka & misiyano mikuru | Conditions kurapwa | Kubudirira | Inishuwarenzi kufukidza uye mutengo kuenzanisa | Zvimwe zvinokanganisa | Kubatana kwezvinodhaka | Yambiro | MIBVUNZO
Chirwere cheshuga chirwere icho inobata pamusoro pe10% yehuwandu hwevanhu vemuUnited States, vane miriyoni imwe nemazana mashanu nezana rezviitiko vachangobva kuongororwa gore rega rega. Chirwere cheshuga chinowanikwa muzvimiro zviviri: Type 1 uye Type 2. Ne Type 1 chirwere cheshuga, muviri hauburitse iyo insulin inodiwa kudzora zvakakwana mwero wehuga yeropa, dzimwe nguva inonzi shuga yeropa. Mune ino kesi, insulin majekiseni ndiyo yekutanga-kurapwa kurapwa. Mutumbi werudzi rwechipiri chirwere cheshuga unogadzira insulin asi usingaishandise nemazvo. Rudzi rwechipiri rwakanyanya kuwanda muUnited States. Mune zvimwe zviitiko, kudya, kurovedza muviri, uye / kana muromo wemashuga mishonga inogona kudzora zvakakwana shuga yeropa. Muzviitiko zvakawanda, zvakadaro, jekiseni re insulin inogona kudikanwa kudzora huwandu hweropa reropa reRudzi rwechipiri chirwere cheshuga zvakare.
Tresiba naLantus mienzaniso miviri ye basal insulin, dzimwe nguva inonzi kumashure kana kwenguva refu-inoshanda insulin. Rudzi urwu rwe insulini rinovimbisa inowirirana mashuga eropa mukati mezuva rese.
Ndeupi musiyano mukuru pakati paTresiba naLantus?
Tresiba (insulin degludec) inonyorwa-inongobaya jekiseni basal insulini inoshandiswa pakurapa kwese Type 1 uye Type 2 chirwere cheshuga mellitus uye inogadzirwa naNovo Nordisk, Inc. Insulin inoitawo basa mukugadzirisa mafuta uye mapuroteni metabolism. Biosynthetic insulins inoshanda senzira yekutsiva kurapa kubatsira varwere vane chirwere cheshuga kudzorera mafuta avo, mapuroteni, uye mashandisiro ehydrohydrate.
Hafu-yeupenyu hwaTresiba maawa makumi maviri neshanu uye haana pachena pachena. Nguva yakareba yekuita kwaTresiba inopa kuringana kweshuga yekudzora shuga mukati mezuva rese ichingoiswa kamwe chete zuva nezuva. Iko hakuna generic vhezheni yeTresiba inowanikwa.
Lantus (insulin glargine) zvakare inonyorwa-chete jekiseni basal insulin inoshandiswa pakurapa kwese Type 1 uye Type 2 chirwere cheshuga mellitus. Lantus inogadzirwa naSanofi. Lantus naTresiba vanoshanda nenzira yakafanana kusimudzira kushandiswa kwakakodzera kwemafuta, mapuroteni, uye makabhohaidhiretsi mune varwere vane chirwere cheshuga. Hafu yeupenyu yeLantus ingangoita maawa gumi nemaviri uye inowanzoiswa kamwe pazuva. Lantus inounzwa nenzira yepashure uye inowanikwa seyakavharika mhinduro mune 10 ml vial mune yakasungirirwa zana mayuniti / ml. Iyo zvakare inowanikwa muLantus Solostar peni yekuendesa chishandiso mune imwechete kusangana.
Iko hakuna FDA inogamuchirwa generic yeLantus. Basaglar, zvakare insulin glargine, ndeye biosimilar insulin kuenda kuLantus uye inogona kuve inodhura mune dzimwe nguva. Toujeo, zvakare insulini glargine, chigadzirwa chitsva chakanyanya kuiswa pamazana matatu / ml. Ichi chigadzirwa chinogona kubatsira muvarwere pamadosi epamusoro kudzora jekiseni vhoriyamu.
| Misiyano mikuru pakati paTresiba naLantus | ||
|---|---|---|
| Tresiba | Lantus | |
| Kirasi yemishonga | Biosynthetic insulin (insulin analog) | Biosynthetic insulin (insulin analog) |
| Brand / generic chinzvimbo | Brand | Brand |
| Chii chinonzi generic zita? | Jekiseni jekiseni | Insulin glargine |
| Ndeapi mafomu (s) ayo mushonga unouya? | Injekiseni mhinduro mune yeFlexPen dhiraivhu dhizaini | Injekiseni mhinduro mune vial kana Solostar peni dhizaini dhizaini |
| Ndeipi muyero wakajairwa? | Kunotsamira pamazinga eropa eropa | Kunotsamira pamazinga eropa eropa |
| Inguva yakareba sei kurapwa kwacho? | Isingaperi | Isingaperi |
| Ndiani anowanzoshandisa mushonga? | Vana nevakuru | Vana 6 uye vakuru, vakuru |
Unoda mutengo wakanakisa paTresiba?
Nyoresa Tresiba yemitengo yambiro uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Mamiriro ezvinhu akarapwa naTresiba naLantus
Tresiba naLantus imwe neimwe inoratidzwa pakurapwa kweType 1 uye Type 2 chirwere cheshuga mellitus. Vanhu vane Type 1 chirwere cheshuga vanoshaya insulin, uye majekiseni ejekiseni ebiosynthetic akadai saTresiba neLantus anoita sekutsiva kurapwa. Vanhu vane Rudzi rwechipiri vanogona kunge vasina kukwana muinsulini, asi zvakare vari insulini inodzivirira, zvichireva kuti muviri wavo haushandise iyo insulin inogadzira nemazvo. Tresiba naLantus vanoita se insulin kutsiva uye kuwedzera mune iyi mhando yechirwere.
| Mamiriro | Tresiba | Lantus |
| Chirwere cheshuga mellitus Rudzi rwekutanga | Ehe | Ehe |
| Chirwere cheshuga mellitus Rudzi rwechipiri | Ehe | Ehe |
Tresiba kana Lantus inoshanda zvakanyanya here?
Meta-ongororo ye 15 kiriniki zvidzidzo rakaburitswa mu2019 rakatarisa data kubva kune vanopfuura zviuru gumi nevatanhatu vakabatanidzwa. Tresiba yakaburitsa kuderera kwakakura mumashuga eropa, asi zvakazara, mhedzisiro yaTresiba naLantus pane hemoglobin A1C (HbA1C) yakanga yakafanana. Tresiba aive nemukana wakakura mushoma wekukonzera hypoglycemia. Vatsvakurudzi vakagumisa kuti nepo huwandu hweglycemic control hwaive hwakafanana, Tresiba inogona kusarudzwa nekuda kwekuderera kwemukana we hypoglycemia.
TO meta-ongororo rakaburitswa muna 2018 raive nezvakafanana Tresiba yaive isinganyanye kukonzeresa zviitiko zve hypoglycemia. Neichi chikonzero, Tresiba anogona kusarudzwa kupfuura Lantus.
Ichi chinyorwa hachina kuitirwa kupa kuraira kwekurapa. Mutapi wako wezvehutano achasarudza kuti ndeapi marudzi einsulini akanakira iwe.
Unoda mutengo wakanakisa paLantus?
Saina kuLantus yemitengo yambiro uye uone kana mutengo uchinja!
Wana machenjedzo emitengo
Kuvhara uye kuenzanisa kwemutengo kweTresiba vs. Lantus
Tresiba imishonga inorayirwa insulin iyo inowanzo kufukidzwa neinishuwarenzi yekutengesa uye zvirongwa zvemishonga zveMedare. Nezvimwe zvirongwa, panogona kunge paine zvirevo zvemafomula, uye iwe ungangoda kutarisa kufukidza kwako nehurongwa hwako kana chemishonga. Wepakati mutengo weimwe 3 ml peni yeTresiba Flextouch 100 yuniti / ml inenge madhora mazana mana pasina inishuwarenzi. Iwe unogona kubhadhara mutengo wakaderedzwa unosvika madhora mazana matatu nemakumi matatu nekoponi kubva kuSingleCare.
Lantus inorondedzerwa insulini iyo inowanzo kufukidzwa neinishuwarenzi yekutengesa pamwe nezvakawanda zvirongwa zveMedare. Zvirongwa zvemafomula zvinogona kukanganisa zvakare kufukidzwa kweLantus. Wepakati mutengo weimwe 3 ml peni inenge madhora zana, asi nekoponi kubva kuSingleCare, unogona kubhadhara madhora makumi manomwe.
Izvo zvakakosha kuti uzive kuti imwe peni yemhando yega yega ye insulin haigare yakaenzana nguva yemurwere mumwe nemumwe. Izvi zvinoenderana neiyo insulin dosi yakatemerwa murwere wega wega.
| Tresiba | Lantus | |
| Kazhinji yakafukidzwa neinishuwarenzi? | Ehe | Ehe |
| Inowanzo kufukidzwa neMedare Chikamu D? | Ehe | Ehe |
| Standard muyero | 1, 3 ml Flextouch 100 yuniti / ml peni | 1, 3 ml Solostar 100 unit / ml peni |
| Chaizvoizvo Medicare copay | Zvinosiyana zvichienderana nehurongwa zvinhu | Zvinosiyana zvichienderana nehurongwa zvinhu |
| SingleCare mutengo | $ 350 + | $ 70 + |
Zvakajairika mhedzisiro mhedzisiro yaTresiba vs. Lantus
Tresiba naLantus vese vane mukana wekukonzera hypoglycemia, kana shuga shoma yeropa. Iyi tsika inowanzosiyana zvichienderana nezvinhu zvakaita sekunge murwere ari Type 1 kana Type 2 chirwere cheshuga, ndeipi imwe insulin kana kurapwa kweshuga murwere angave achishandisa, uye kudya. Paunenge uchishandisa Tresiba kana Lantus ine pfupi-inoshanda kana nekukurumidza-kuita insulins, iyi njodzi inowedzera.
Varwere vanofanirwa kuve nekwaniso yekutarisa yavo yeropa glucose mazinga pamwe neyechinyakare mita kana inoenderera glucose yekutarisa system (CGMS). Varwere vanofanirwawo kudzidziswa zviratidzo nezviratidzo zveakanyanya hypoglycemia, sezvo inogona kutyisidzira hupenyu. Izvi zvinosanganisira kuzungunuka, kuchena musoro, kuvhiringidzika kwepfungwa, kuda kurutsa, kuona kwakashata, uye kutemwa nemusoro. Hypoglycemia inogona kudzoserwa nekumwa kweshuga kana kuitiswa kwejekiseni Glucagon.
Injection saiti saiti inogona kunetsa kumurwere. Izvi zvinogona kusanganisira kutsvuka, kuchenesa, kana kupwanya. Rotating jekiseni nzvimbo dzinogona kubatsira kudzikisa kana kurerutsa zviratidzo izvi.
Iyi rondedzero haina kuitirwa kuti ive yakazara runyorwa rweanogona kuve mhedzisiro mhedzisiro. Ndokumbirawo ubvunze wako wekuchengeta hutano kuti uwane yakazara runyorwa.
| Tresiba | Lantus | |||
| Side maitiro | Zvinoshanda? | Kakawanda | Zvinoshanda? | Kakawanda |
| Allergic maitiro | Ehe | 0.9% | Ehe | Hazvina kutsanangurwa |
| Itching | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Mapundu | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Jekiseni saiti yekuita | Ehe | 3.8% | Ehe | Hazvina kutsanangurwa |
| Ganda kuomesa kana kukanda panzvimbo yejekiseni (lipodystrophy) | Ehe | 0.3% | Ehe | Hazvina kutsanangurwa |
| Kutemwa nemusoro | Ehe | 12% | Ehe | 5-10% |
| Kurera huremu | Ehe | Hazvina kutsanangurwa | Ehe | Hazvina kutsanangurwa |
| Hypoglycemia (yakaderera ropa shuga) | Ehe | 10-12% | Ehe | 6-10% |
| Kuzvimba kwemaoko nemakumbo (peripheral edema) | Ehe | 0.9-3% | Ehe | makumi maviri% |
Kwayaka: Tresiba ( Zuva Nezuva Lantus ( Zuva Nezuva )
Kubatana kwezvinodhaka kwaTresiba vs. Lantus
Kune makirasi mazhinji emishonga inorwisa chirwere cheshuga, uye kazhinji, vanhu vane Type 2 chirwere cheshuga vangangoda mubatanidzwa wezvirwere zvakasiyana-siyana zvekudzivirira hyperglycemia (yakakwira shuga yeropa). Nehurombo, kusanganiswa kwemishonga yakawanda inoitirwa kudzikisa shuga yeropa kunogona kudzikisira huwandu hweglucose zvakanyanya, zvichikonzera hypoglycemia. Varwere vanofanirwa kuongororwa zvakanyanya pavanoshandisa Tresiba neLantus pamwe chete nemimwe mishonga inorwisa chirwere cheshuga senge metformin uye glyburide. Thiazolidinediones, senge pioglitazone, inogona kuita kuti varwere vakanyanya kutarisana ne hypoglycemia. Yako dose yeTresiba kana Lantus ingangoda kuchinjika kazhinji.
Kirasi yakajairika yemishonga inodzvinyirira inozivikanwa seangiotensin-inoshandura enzyme (ACE) inhibitors yakaratidzirwa kuwedzera insulin senzwi. Paunenge uchishandisa madhiragi aya kurapa kukwirisa kweropa mune varwere vane chirwere cheshuga vachitorawo Tresiba kana Lantus, njodzi yehypoglycemia inowedzerwa. Varwere vanofanirwa kuongororwa nezviratidzo zve hypoglycemia kana musanganiswa uyu ukaonekwa wakakodzera.
Izvi hazviitirwe kuve runyorwa ruzere rwekudyidzana kwezvinodhaka kwaTresiba naLantus. Ndokumbirawo ubvunze wemishonga wako kana mupi wezvehutano kuti uwane runyorwa rwakakwana.
| Zvinodhaka | Kirasi yemishonga | Tresiba | Lantus |
| Benazepril Captopril Enalapril Fosinopril Lisinopril Quinapril | Angiotensin-inoshandura enzyme (ACE) inhibitors | Ehe | Ehe |
| Isocarboxazid Selegiline Phenelzine | Monoamine oxidase (MAO) inhibitors | Ehe | Ehe |
| Metformin Glyburide Glipizide Repaglinide Pioglitazone Sitagliptin Saxagliptin | Antidiabetic zvinodhaka | Ehe | Ehe |
| Sulfamethoxazole | Sulfonamide mishonga inorwisa mabhakitiriya | Ehe | Ehe |
| Hydrochlorothiazide Furosemide Chlorthalidone | Diuretics | Ehe | Ehe |
| Prednisone Methylprednisolone | Corticosteroids | Ehe | Ehe |
| Chlorpromazine Fluphenazine Prochlorperazine | Zvigadzirwa zvePhenothiazine | Ehe | Ehe |
| Lithium Clozapine Olanzapine | Antipsychotic | Ehe | Ehe |
| Estradiol Ethinyl Estradiol Norethindrone Norgestimate Desogestrel Progesterone | Mishonga yekudzivirira | Ehe | Ehe |
| Atenolol Bisoprolol Carvedilol Labetalol Metoprolol Sotalol | Beta anovharira | Ehe | Ehe |
| Levothyroxine Liothyronine | Utachiona mahormone | Ehe | Ehe |
| Aspirin Magnesium salicylate Bismuth subsalicylate | Salicylates | Ehe | Ehe |
| Fluoxetine | Kusarudza serotonin reuptake inhibitor (SSRI) | Ehe | Ehe |
Yambiro dzaTresiba naLantus
Tresiba naLantus vane njodzi yehypoglycemia, kana yakaderera ropa glucose mazinga. Varwere paTresiba kana Lantus vanofanirwa kuziva zviratidzo nezviratidzo zve hypoglycemia, izvo zvinosanganisira kuzungunuka, hura hwakareruka, kuvhiringidzika kwepfungwa, kuda kurutsa, kuona kwakashata, uye musoro.
Hypokalemia, kana yakaderera potasiamu mazinga, zvakare chiitiko chinokanganisa chine chekuita neTresiba kana Lantus kushandiswa. Izvi zvinonyanya kukosha kufunga kune varwere vane hutachiona hwakakanganisika basa kana vangave vari potassium-kurasa mishonga yakadai se furosemide.
Insulin kuendesa zvishandiso, senge Flextouch kana Solostar peni, pamwe nepeni tsono uye majekiseni, hazvifanirwe kugoverwa pakati pevarwere. Iko kune njodzi yekuyambuka-kusvibiswa nehutachiona hunokonzerwa neropa nezvirwere. Varwere vanofanirwa kuwana dzidzo uye kurairwa pamusoro pekutanga chirwere cheshuga, kusanganisira kushandiswa kwakachengeteka kwetsono.
Tresiba naLantus vanoitirwa subcutaneous dosing chete. Havafanirwe kupihwa mukati mehusimbe kana mukati.
Inowanzo bvunzwa mibvunzo nezve Tresiba vs. Lantus
Chii chinonzi Tresiba?
Tresiba (insulin degludec) ndeyekureba-kuita basal insulin iyo inowanzoiswa kamwe chete zuva nezuva. Inowanikwa chete sekunyora. Tresiba inowanikwa muFlexTouch peni kuburitsa system muzvikamu zvezana zviyero / ml uye mazana maviri / ml.
Chii chinonzi Lantus?
Lantus (insulin glargine) ndeyekureba-kuita basal insulin iyo inowanzo dosedwa kamwe chete zuva nezuva. Inowanikwa chete sekunyora. Lantus inowanikwa mune Solostar peni yekuendesa system mune yakasungirirwa zana mayuniti / ml uye mune 10 ml vial yeiyo 100 mayuniti / ml kusangana.
Tresiba naLantus vakafanana here?
Tresiba naLantus ndeimwe-yakareba-inoshanda, basal insulins, asi haina kufanana. Tresiba is insulin degludec uye ane hafu yeupenyu hwakareba maawa makumi maviri nemashanu. Lantus insulini glargine uye ine ipfupi hafu-hupenyu hwemaawa gumi nemaviri. Ose ari maviri akaiswa dosed kamwe zuva nezuva.
Tresiba kana Lantus zvirinani here?
Nepo glycemic kutonga kwakafanana pakati paTresiba naLantus, data rinoratidza kuti Tresiba inogona kunge isingaite mukana wekutungamira kune zvine njodzi hypoglycemic zviitiko. Neichi chikonzero, Tresiba anogona kusarudzika, kunyanya kune varwere vanogara kana vane nhoroondo ye hypoglycemia.
Ndinogona here kushandisa Tresiba kana Lantus ndichiri nepamuviri?
Tresiba anorondedzerwa sepamuviri nharaunda C neKudya neDrug Administration (FDA). Kune zvidzidzo zvemakiriniki zvekutsigira mashandisiro uye kuchengetedzeka pakubata. Lantus chikamu B nekuda kwekuti zvidzidzo zvakaratidza kuti kune njodzi yakaderera yekukuvara kwechibereko. Lantus inowanzoonekwa yakachengeteka pakubata.
Ndinogona here kushandisa Tresiba kana Lantus nedoro?
Iko kushandiswa panguva imwe chete kwaTresiba kana Lantus nedoro kunotakura njodzi ye hypoglycemia. Kunwa doro, kunyanya padumbu risina chinhu, kunotadzisa gluconeogenesis. Izvi zvinotungamira kunguva yakareba njodzi yeshuga yeropa shoma.
Ndeipi insulin yakafanana neLantus?
Basaglar biosimilar kuna Lantus, kunyange isiri FDA-inogamuchirwa generic yeLantus uye haina kutsiva Lantus. Ose maviri Lantus neBasaglar insulini glargine mune yakasungwa zana mayuniti / ml.
Ndeipi nguva yakanakisa yekutora Tresiba?
Tresiba inogona kupihwa chero nguva yezuva pasina hanya nenguva yekudya, asi zvakakosha kupa mushonga panguva imwechete mazuva ese.
Ndeipi imwe nzira yakanaka kune Tresiba?
Toujeo ndeye basal insulin inowanikwa mune yakakwira yakadzika mazana mazana matatu / ml. Kukwirira kwakanyanya mumasal insulins anotendera varwere vane yakakwira madhizaini kujowa mashoma vhoriyamu.
