FDA inodhonza ese mafomu e ranitidine kubva kumusika weUS

Nhau

Ranitidine, inowanzozivikanwa nezita rayo rechiratidzoZantac, mushonga unoderedza kugadzirwa kwemudumbu asidi. Inowanzo kutorwa kurapa chirungurira uye GERD. Musi waSeptember 13, 2019 iyo U.S. Chikafu uye Dhijitari Administration (FDA) yakaburitsa a chirevo kuzivisa kuvapo kunozivikanwa kwekusachena kwe nitrosamine inonzi N-nitrosodimethylamine (NDMA) mune mimwe mishonga yeRititidine, kusanganisira Zantac - zvichikurudzira zvimwe zvitoro zvezvinodhaka kumisa kutengeswa kwezvigadzirwa zvese zveRititidine Musi waApril 1, 2020, iyo FDA yakabvunza vagadziri vezvinodhaka kuti vatore mhando dzese dzeRititidine kubva kumusika weU.S.

Nei ranitidine ichirangarirwa?

Iyo FDA yanga ichiongorora NDMA uye imwe nitrosamine yakasviba mukumanikidza kweropa uye nemoyo kutadza mishonga inonzi Angiotensin II Receptor Blockers (ARBs) kubvira gore rapfuura, chirevo chekutanga chakaverengwa. Panyaya yeARBs, iyo FDA yakurudzira akawanda ekurangarira sezvaakawana zvisingagamuchirike mazinga enitrosamines.

Tiye chirevo chepakutanga akagumisa kuti bvunzo dzekutanga dzakasimbisa ranitidine ine yakaderera masosi e NDMA. Izvi zvakakonzera makambani emishonga Novartis (ayo anoita ese Zantac uye generic vhezheni yemarititidine mishonga) uye Apotex (iyo inoita Wal-Zan) kurangarira zvese zvavo generic ranitidine zvigadzirwa zvinotengeswa muUS.

Maketani makuru emakemikari akaburitsa Zantac kubva pamashefu avo. Mune chirevo , CVS yakaburitsa pachena kuti chiito ichi chiri kutorwa kunze kwekuwanda kwekuchenjerera, uye danho rekudhonza ranitidine zvigadzirwa kubva mumashalofu zvakaitwa zvakananga mukupindura kune chenjedzo yechigadzirwa kubva kuUS Food and Drug Administration (FDA) ichiti ranitidine zvigadzirwa zvinogona kunge zvine yakaderera nhanho NDMA.

MunaGunyana, Ramzi Yacoub, Chief Pharmacy Officer weSingleCare, akatsanangura, Iyo FDA ichangobva kuona kumwe kusviba mune zvimwe zvigadzirwa zveRititidine uye yakapa yekuzvidira kuyeuka panguva ino. Izvi hazvikanganise zvigadzirwa zve ranitidine panguva ino. Iyo FDA iri kuenderera kuyedza ranitidine zvigadzirwa kubva kwakasiyana zvigadzirwa kuti ienderere mberi kuongorora izvo zvinogona kuve mhedzisiro.

MunaEpril wegore rino, iyo FDA yakazivisa kuti mushure mekumwe kuferefetwa, sangano rakawana huwandu hweNDMA hunowedzera nekufamba kwenguva mune zvakajairika mamiriro ekuchengetedza. Matanho eNMDA akawanikwa zvakare achiwedzera zvakanyanya kana ranitidine ichengetwa pamatembiricha akanyanya. Zvinoreva, vatengi vanogona kuburitswa kune yakatowanda yakawanda NDMA. Izvi zvakawanikwa zvakakurudzira iyo FDA kuburitsa yakaomesesa rangarira chikumbiro .

Zvokuita kana iwe ukatora ranitidine

Mamirioni evaAmerican anoshandisa ranitidine - mushonga-simba uye pamusoro-pekutengesa - kugadzirisa matambudziko akasiyana ekugaya. Iyo inoshandiswa zvakanyanya kushandiswa H2 blocker mishonga inovhara chiito che histamine uye inoderedza acid-kugadzirwa mudumbu. Muchokwadi, zvakajairika kuti vanhu vatore kaviri pazuva, kana kupfuura. Avo vanoonekwa kuti vane Zollinger-Ellison syndrome kazhinji vanotora ranitidine katatu pazuva.

Iyo FDA inokurudzira kuti utaure nachiremba wako kana uri kutora mushonga-simba ranitidine usati wamisa mushonga. Chero ani anotora simba repamusoro-re-rekodhi anofanira kurega kuitora, ongorora dzimwe nzira nerubatsiro rwewemishonga, uye adzosere mishonga yekudzoserwa. Iwe unogona zvakare kumhan'arira chero kusagadzikana kusagadzikana kana nyaya dzemhando yepamusoro kune iyo FDA's MedWatch Yakashata Chiitiko Kuzivisa chirongwa.

Ndedzipi dzimwe nzira?

Kunyangwe ranitidine ichirangarirwa, chero munhu anoda iyo asidhi-inoderedza mishonga unogona kuwana zororo. Mamwe maH2 blockers, senge Pepcid uye Tagamet , achiri kuwanikwa pamusoro pekambani kuti ape chirungurira uye kugadzikana kwekugaya, uye hazvina kumborangarirwa.

Antacids senge Rolaids , Matumamu , uye Mylanta inogona kuva sarudzo dzakanaka dzekurwadziwa pahuro uye kugadzikana kwekugaya. Pamusoro pezvo, proton pump inhibitors (PPIs) senge Nexium , Prilosec , uye Prevacid inogona zvakare kupa zororo pasina kunetseka nezve NDMA. Zvisinei, maPPI ane simba uye ane mamwe mapako anofanira kutaurwa nachiremba wako.

Taura nachiremba wako kutanga

Kana uchichinja mishonga, taura nehunyanzvi uye dzidza chokwadi nezve izvo zviripo uye zvinofungidzirwa senzira yakachengeteka yezvaunoda chaizvo. Iyo FDA inoratidza kutarisa zvimwe zvigadzirwa zveOTC zvemamiriro ako, kana zvakakodzera. Nekuti mishonga yakawanda-yekudzikisa asidhi inongoshandiswa pakurapa kwenguva pfupi, chiremba wako anogona zvakare kusarudza kurega mushonga.

Varwere vanoshuva kurega ranitidine uye vachichinjira kune imwe nzira yekurapa vanofanirwa kukurukura izvi nachiremba, Dr. Yacoub vanopa zano. Kune mimwe mishonga inowanikwa mukirasi imwechete iyi kana mamwe makirasi ekurapa mamiriro ako-asi varwere vanofanira kutaurirana nachiremba wavo kana chiremba vasati vaita shanduko.