Kuru >> Zvinodhaka Info >> Trintellix mhedzisiro, kudyidzana, uye maitiro ekuzvidzivirira

Trintellix mhedzisiro, kudyidzana, uye maitiro ekuzvidzivirira

Trintellix mhedzisiro, kudyidzana, uye maitiro ekuzvidziviriraZvinodhaka Info

Trintellix mhedzisiro | Kurera huremu | Kurega | Inotora nguva yakareba sei mhedzisiro? | Yambiro | Kudyidzana | Maitiro ekudzivirira mhedzisiro

Trintellix (chinhu chinoshanda: vortioxetine) izita rezita remushonga mushonga unorapa kushushikana kukuru kwekushushikana (MDD). Vortioxetine, chinhu chinoshanda muTrintellix, zviyero serotonin muuropi, iyo inogona kubatsira kugadzirisa manzwiro, ndangariro, uyekugadzirisa basamune avo vane kushushikana. Trintellix mushonga unoshanda, asi inogona kunge isiri iyo chaiyo mishonga kune wese munhu nekuda kwemhedzisiro mhedzisiro.



RELATED: Dzidza zvakawanda nezve Trintellix | Tora Trintellix discounts



Zvakajairika mhedzisiro mhedzisiro yeTrintellix

Mhedzisiro inowanzoitika yeTrintellix ndeiyi:

  • Nausea
  • Manyoka
  • Muromo wakaoma
  • Dzungu
  • Kuzvimbirwa
  • Kusvipa
  • Kubata ropa
  • Zviroto zvisina kujairika
  • Itching
  • Kusagadzikana pabonde

Kukotsira hakuzivikanwe kuve kwakajairika divi mhedzisiro ye vortioxetine. Pane kudaro, vortioxetine inogona kuvandudza maitiro ekurara uye anobatsira kudzikisira kukotsira masikati.



Trintellix uremu hunoshanduka

Zvinodzvinyirira, kunyanya inosarudza serotonin reuptake inhibitors (SSRIs), inozivikanwa nekubatana nekurema kuwedzera, asi kana vari chaizvo kukonzera kurema kuwedzera kuri kure chokwadi . Trintellix, kune rumwe rutivi, inoita kunge iine mashoma mhedzisiro pahuremu hwemuviri. In zvidzidzo zvekiriniki iyo yakatevera varwere kweinopfuura mwedzi mitanhatu, Trintellix, yaidaidzwa kunzi Brintellix, yakanga isina chakakosha pahuremu hwemuviri. A gare gare kudzidza kwegore , zvakadaro, vakaratidza varwere vakawana avhareji yeimwe (1) pondo vachiri paTrintellix. Vangaita 18% yevadzidzi vakatora Trintellix vakawana kana kurasikirwa ne7% yehuremu hwavo hwepakutanga pakutanga kwekudzidza. Trintellix, saka, ine zvishoma zvainoita pahuremu kupfuura mamwe antidepressants, asi huremu shanduko inogoneka uye inosiyana nemunhu.

Trintellix kurega

Kunge mishonga yese inokanganisa serotonin muuropi, Trintellix haifanire kumiswa pakarepo. Kunyangwe mushonga uyu usiri muropa, iwo muyero unofanirwa kudzikira zvishoma nezvishoma kwemavhiki akati wandei usati wamira kudzivirira zviratidzo zvekumisa. Iwo anowanzozivikanwa Trintellix discontinuation zviratidzo ndeaya:

  • Nausea
  • Kudikitira
  • Kusagadzikana
  • Kushatirwa
  • Dzungu
  • Kufunganya
  • Kuvhiringidzika
  • Kusarara

Discontinuation syndrome zviratidzo zvinogona kutora maawa mashoma kusvika mazuva matatu kuoneka uye inogona kuramba iine vhiki imwe chete kana maviri. Kazhinji, izvi zviratidzo zvinogadzirisa pasina kurapwa muvhiki imwe chete kana mbiri.



Yakakomba mhedzisiro mhedzisiro yeTrintellix

Trintellix inogona kukonzera zvakakomba mhedzisiro inosanganisira:

  • Kuzviuraya pfungwa uye maitiro
  • Serotonin chirwere
  • Zvinetso zvekubuda ropa
  • Mania kana hypomania mune varwere vane bipolar kusagadzikana
  • Angle-kuvhara glaucoma
  • Low sodium mazinga
  • Yakanyanya kugarisana, kusanganisira anaphylaxis kana angioedema

Kuzviuraya

Trintellix inouya neiyo FDA nhema bhokisi inonyevera kuti vana, vachiri kuyaruka, uye vechidiki vari mungozi yekuzviuraya uye maitiro. Kana uchitora Trintellix, varwere vadiki vanofanirwa kutariswa zvakanyanyazviratidzo zvekuzviurayazvakaita se:

  • Pfungwa kana kutaura pamusoro pekuzviuraya
  • Kuedza kuzviuraya
  • Mamiriro asina kujairika anochinja
  • Hasha, kutsamwa, kana hukasha
  • Kusagadzikana kana kusagadzikana
  • Nyowani kana kuwedzera kushushikana
  • Nyowani kana kuwedzera kunetseka
  • Kutya kwekutya
  • Maitiro asina kujairika
  • Maitiro ekutora njodzi kana mafungiro ane njodzi

Serotonin chirwere

Mishonga yekudzvinyirira senge vortioxetine inogona kukonzera serotonin syndrome, mamiriro anogona kuva nenjodzi anokonzerwa neserotonin yakawandisa muuropi. Rega Trintellix nekukurumidza uye tsvaga kurapwa pazviratidzo zve serotonin syndrome, senge:



  • Kusagadzikana
  • Hallucinations
  • Kurasikirwa kwekubatana
  • Tsvina ichinyemwerera
  • Mitsipa yakaoma
  • Kukurumidza kurova kwemoyo
  • Yakakwira kana yakaderera BP
  • Kudikitira
  • Kupindwa nechando
  • Kusvotwa kana kurutsa
  • Kuvhiringidzika
  • Maitiro anochinja
  • Manyoka
  • Kufenda

Yakaderera ropa sodium

Serotonergic zvinodhaka senge vortioxetine inogona kukonzera SIADH, dambudziko nehormone iyo inodzora kubviswa kwemuviri wemvura nemaelectrolyte kubva mumuviri. SIADH zvakare inogona kukonzera kuwanda kwemunyu (sodium) muropa kudonha, mamiriro anonzi hyponatremia. Low blood sodium inogona kuva yakakomba uye inogona kuva nengozi mamiriro ekurapa, saka tsvaga kurapwa pazviratidzo zvehyponatremia inosanganisira:

  • Kuvhiringidzika
  • Kurasikirwa kwendangariro
  • Kutemwa nemusoro
  • Nausea
  • Zvakaoma kuisa pfungwa
  • Kusadzikama
  • Hallucinations
  • Kufenda
  • Kufenda
  • Idya

Angle-kuvhara glaucoma

Angle-kuvhara glaucoma zvinogona kuitika kamwe-kamwe uye kukonzera kurasikirwa kwemaonero kana hupofu mumaawa mashoma kana mazuva. Izvo zvinoitika kana iyo yekudonha gadziriro yeziso iri pakati pe iris uye iyo cornea yakavharwa, zvichikonzera fluid kuti ikurumidze kuunganidzwa mukati meziso. Tarisa zviratidzo zvakadai se:

  • Kurwadziwa kweziso
  • Chiono chinoshanduka
  • Akatsvuka kana kuzvimba maziso
  • Kutemwa nemusoro

Vanhu vane makona matete pakati peiris uye cornea vari panjodzi yekuvandudza glaucoma yekona. Kuongororwa kwemakona madiki kunogona kuitwa panguva yekuongororwa kwemaziso. Makona mapfupi anorapwa kuburikidza nekuvhiya.



Yakareba sei Trintellix mhedzisiro mhedzisiro?

Iwo akanyanya kuwanda Trintellix mhedzisiro ndeechinguvana uye anowanzo kupera mukati memazuva mashoma mushure mekunge mushonga wamiswa. Mhedzisiro yakakomba mhedzisiro, zvisinei, zvinogona kutora nguva yakareba kuti zvigadziriswe. Zviitiko zvakapfava zve serotonin syndrome zvinowanzogadzirisa mukati memazuva maviri kana matatu ekurega mushonga, asi zviitiko zvakakomba zvinoda kurapwa nekukurumidza. Muzviitiko zvinoratidza zviratidzo zveropa yakaderera yerodium, Trintellix inofanira kumiswa uye mupi wezvehutano anofanirwa kutaurwa naye. Mhosva dzakakomba dzeropa rakaderera sosi mazinga angangoda kuchipatara.

Trintellix zvinopesana & yambiro

Trintellix inogona kunge isiri iyo chaiyo mishonga kune wese munhu. Nezvikonzero zvakasiyana siyana, vamwe vanhu vanogona kutadza kutora mishonga iyi vamwewo vangangwarira vasati vatanga.

Allergies

Chero ani ane chirwere chakakomba kuTrintellix haafanire kutora mushonga.



MAO inhibitors

Vanhu vanotora monoamine oxidase inhibitors (MAOIs), kirasi yemishonga inosanganisira mamwe marudzi eanodzvinyirira, maantibayoti, kana madhiragi anorapa chirwere cheParkinson, haazopihwa Trintellix kudzamara varega kutora MAO inhibitors kwemazuva gumi nemana.

Varombo metabolism

Vamwe vanhu havatyori vortioxetine zvakanyanya. Mushonga uyu unoramba uripo kwenguva yakareba mumuviri pakukwirisa, zvichiwedzera njodzi yemhedzisiro. Neraki, vanhu vanogona kuongororwa majini. Varombo metabolizers inongotenderedzwa kune yakanyanya zuva nezuva dhizaini yemamirigiramu gumi (mg).

Vana

Trintellix is ​​FDA inogamuchirwa kuti ishandiswe muvakuru vane makore 18 zvichikwira. Trintellix haisati yakatemwa seyakachengeteka kana inoshanda muvana.

Vakuru

Mumakiriniki ekuedzwa , Trintellix yakaratidzirwa kuve inoshanda uye yakachengeteka kune varwere vane makore anodarika makumi matanhatu nemashanu. Hapana gadziridzo yedosi inodiwa.

Kubata uye kuyamwisa

Iko hakuna kukwana kwakaringana kana ruzivo rwunoona kuti Trintellix yakachengeteka kutora panguva yekuzvitakura. Vanhu vane nhumbu kana vanofunga nezvepamuviri vanofanirwa kutsvaga zano rezvechiremba kubva kune wezvehutano vasati vatanga kana kurega Trintellix.

Saizvozvowo, hapana kukwana kwakaringana kana ruzivo rwekuti Trintellix inopinda mumukaka wemukaka kana kukanganisa mwana anoyamwa. Iyo Dhiragi uye Lactation Dhatabhesi (National Raibhurari yeMishonga) kundichakuwona gare gare vanaamai vari kutora Trintellix kuchinjira kumimwe mishonga vasati vayamwisa mwana. Imwe nzira kutsvaga imwe nzira yekudyisa mucheche.

Trintellix kudyidzana

Trintellix ine kudyidzana kwezvinodhaka uko kunogona kukonzera akasiyana mhedzisiro.

Trintellix uye MAO inhibitors

Trintellix haifanire kutorwa ne monoamine oxidase inhibitors (MAOIs). Kubatanidza Trintellix ne MAO inhibitor kunogona kukonzera serotonin syndrome. Iyi mishonga inosanganisira:

  • Mushonga (tranylcypromine)
  • Marplan (isocarboxazid)
  • Nardil (COM) phenelzine )
  • Zyvox (linezolid)
  • Sivextro (tedizolid)
  • Emsam (selegiline)
  • Xadago (safinamide)
  • Methylene bhuruu jekiseni

Trintellix uye serotonergic zvinodhaka

Zvinodhaka zvinokwidziridza mazinga eserotonin anonzi serotonergic zvinodhaka. Mimwe yemishonga iyi ine simba guru pane serotonin, nepo vamwe vasina. Njodzi yeserotonin syndrome yakanyanya kuderera asi inowedzera kana maviri kana anopfuura madhiragi eserotonergic akatorwa pamwechete. Neichi chikonzero, kubatanidza mimwe serotonergic zvinodhaka naTrintellix inofanirwa kudzivirirwa. Izvi zvinosanganisira:

  • Zvinodzvinyirira zvakaita se
    • Tricyclic antidepressants
    • SSRIs (inosarudza serotonin reuptake inhibitors), senge citalopram, paroxetine, sertraline, kana fluoxetine
    • SNRIs (inosarudza serotonin uye norepinephrine reuptake inhibitors), senge duloxetine kana venlafaxine
    • Wellbutrin (bupropion)
  • Kunetseka mishonga senge buspirone
  • Zvinokurudzira
  • Zvinodhaka zvinorapa kana kudzivirira kusvotwa
  • Kosora mishonga iine dextromethorphan
  • Migraine mishonga kusanganisira triptans uye ergot zvinodhaka
  • Opioid senge tramadol kana fentanyl
  • Antipsychotic
  • Anticonvulsants senge carbamazepine kana phenytoin
  • Mishonga yaPasinson
  • Lithium
  • Mishonga inowedzera dzakadai saSt. John's wort, tryptophan, kana Yohimbe

Trintellix uye ropa rakatetepa (anticoagulants)

Trintellix inomutsa njodzi yematambudziko ekubuda ropa, saka kurapwa kuchada kuongororwa kana munhu achitorawo-vanocheka ropa, senge warfarin kana Plavix (clopidogrel). Nonsteroidal anti-inflammatory drugs (NSAIDs), senge aspirin uye ibuprofen, zvakare inopindira nekugwamba kweropa, saka inofanirwa kushandiswa zvishoma pakutora Trintellix. Mimwe anticancer zvinodhaka zvakare zvinomutsa njodzi yekubuda ropa zvikamu kana zvatorwa naTrintellix. Chekupedzisira, steroids inogona kukonzera kubuda kwemudumbu. Ngozi yematambudziko ekubuda ropa inowedzera kana mishonga iyi ikatorwa neTrintellix.

Vanhu vazhinji havazive kuti zvimwe zvinozivikanwa zvekudya uye zvemakwenzi zvinowedzera zvinokanganisa kuvhara ropa, saka izvi, zvakare, zvinofanirwa kushandiswa zvishoma pakutora Trintellix. Zvinosanganisira:

marapirwo echirume mbiriso hutachiona kumba
  • Garlic
  • Ginkgo
  • Krill mafuta
  • Akaona palmetto
  • Willow kuhukura

Trintellix uye diuretics

Trintellix inomutsa njodzi yemazinga epasi e-sodium muropa. Diuretiki (mapiritsi emvura) anogona kubatsira kuchinetso nekuwedzera kubuda kwesodium. Therapy ine diuretics ingangoda kuongororwa kana kuchinjwa. Sulfonylurea zvinodhaka, zvakatemerwa kudzora shuga yeropa mune varwere vane mhando 2 chirwere cheshuga, vachadaro zvakare kuwedzera njodzi yesodiyamu yakaderera muvanhu vanotora Trintellix.

Mishonga inoderedza kushanda kweTrintellix

Mimwe mishonga inomhanyisa metabolism yemuviri wevortioxetine, ichideredza kushanda kwayo. Izvi zvinosanganisira:

  • Iyo mishonga inorwisa mabhakitiriya rifampin, rifapentine, rifamycin, rifaximin, uye rifabutin
  • Dzimwe mhando dze anticonvulsant zvinodhaka
  • Dzimwe mhando dze antiviral zvinodhaka
  • Barbiturates dzakadai sebutalbital uye butabarbital

Paunenge uchitora iyi mishonga, iyo Trintellix dose inogona kuda kuwedzerwa.

Zvinodhaka zvinowedzera mhedzisiro yeTrintellix

Mimwe mishonga inoderedza metabolism yemuviri wevortioxetine, ichiwedzera kuitika uye kuomarara kwemhedzisiro inogona kuitika. Izvi zvinosanganisira:

  • Vamwe mishonga inodzvinyirira saWellbutrin (bupropion), Paxil (paroxetine), kana Prozac (fluoxetine)
  • Mimwe mishonga inobata isina kujairika kurova kwemoyo zvakadai sequinidine

Mubatsiri wezvehutano angangoda kudzikisa iyo Trintellix dose neinosvika hafu kana yatorwa nemishonga iyi.

Trintellix uye doro

Iko hakuna humbowo kunwa doro kunokonzeresa kukanganisika paunenge uchitora vortioxetine. Mugadziri, zvakadaro, anopa zano vanhu kuti vadzivise kunwa doro vachitora Trintellix.

Maitiro ekudzivirira Trintellix mhedzisiro

Haasi munhu wese anotora Trintellix anozove nemhedzisiro. Kune avo vanoita, mhedzisiro inowanzo kuve shoma. Kune, zvisinei, kune mashoma nzira dzekudzora njodzi yemhedzisiro:

1. Tora Trintellix sekurairwa

Tora dosi yakatemwa, kazhinji 5 kusvika 20 mg kamwe pazuva. Usatore mishonga yekuwedzera, cheka muyero, kana kusvetuka zuva kana maviri. Trintellix inogona kutorwa nekudya kana pane isina chinhu mudumbu.

2. Usarega kutora Trintellix pakarepo

Dzivisa kumisa Trintellix zvese kamwechete. Panogona kunge paine mhedzisiro. Kana mushonga wacho uchiratidzika kunge usiri kushanda kana mhedzisiro yakaoma kutora, taura nachiremba anorayira, wemishonga, kana mumwe nyanzvi yehutano nezve kushandura dhizaini kana kuchinjira kumushonga mutsva. Kana zvichibvumiranwa mushonga unofanirwa kumiswa, nzira yakanakisa ndeyekudzikamisa muyero zvinoenderana nemirayiridzo yemupi wezvehutano.

3. Usapotsa madhiri

Kufanana neanodzvinyirira ese, vanhu vanowana zvishoma kubatsirwa kubva kumushonga kana vakapotsa madosi. Kana akawandisa madosi akashayikwa mumutsara, zviratidzo zvechimiro chiri kurapwa zvinogona kudzoka. Izvo zvinobatsira kuchengeta diary yemushonga, kushandisa chirongwa chekurapa, kumisikidza bhokisi remapiritsi remazuva manomwe, kana kuseta alarm yezuva rega rega.

4. Udza chiremba nezvehutano hwese

Kugovera yakazara nhoroondo yezvokurapa kunogona kubatsira kudzivirira mhedzisiro. Usati watanga Trintellix, udza chiremba wako kana iwe uine chero cheanotevera:

  • Nhoroondo yekubatwa
  • Chero matambudziko ane yakaderera sodium
  • Chero matambudziko nekubuda ropa
  • Mania kana bipolar kusagadzikana
  • Glaucoma

Uyezve ita shuwa kuti iwe unotaurira chiremba nezve nhumbu, kuyamwisa, kana chero hurongwa hwekuita nhumbu kana kuyamwisa mwana.

5. Udza chiremba nezvemishonga yose iri kutorwa

Trintellix ine akawanda akashata mhedzisiro nekuda kwekubatana kwezvinodhaka. Udza chiremba anorondedzera nezve zvese iyo mishonga uye zvinowedzera zvaunotora, kunyanya:

  • Mishonga inobata manzwiro, kushushikana, psychosis, kana zvimwe zvinetso zvepfungwa
  • MAO inhibitors
  • Ropa rakapfava
  • Diuretics
  • Migraine mishonga
  • Mishonga inorwadza yakadai seopioid kana NSAIDs
  • Anticonvulsants
  • Rifampicin
  • Quinidine
  • Yese-pamushonga mishonga, zvinowedzera, uye mishonga yemakwenzi yaunotora, kunyanya St. John's wort uye tryptophan

Kana iwe usina chokwadi nezve mushonga, chiremba, wemishonga, kana mumwe mupi wezvehutano anogona kukubatsira kuti uzive. Kana iwe uri kutora maviri kana anopfuura emishonga ekurapa, chengeta rondedzero yeiyi ese mishonga iri paruoko. Iva wakagadzirira kubvunza rondedzero iyi kana uchitaura nachiremba wezvehutano.

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